Ontology type: schema:ScholarlyArticle Open Access: True
2017-07
AUTHORSRainer Kraehenmann, Dan Pokorny, Leonie Vollenweider, Katrin H. Preller, Thomas Pokorny, Erich Seifritz, Franz X. Vollenweider
ABSTRACTRATIONALE: Accumulating evidence indicates that the mixed serotonin and dopamine receptor agonist lysergic acid diethylamide (LSD) induces an altered state of consciousness that resembles dreaming. OBJECTIVES: This study aimed to test the hypotheses that LSD produces dreamlike waking imagery and that this imagery depends on 5-HT2A receptor activation and is related to subjective drug effects. METHODS: Twenty-five healthy subjects performed an audiorecorded guided mental imagery task 7 h after drug administration during three drug conditions: placebo, LSD (100 mcg orally) and LSD together with the 5-HT2A receptor antagonist ketanserin (40 mg orally). Cognitive bizarreness of guided mental imagery reports was quantified as a standardised formal measure of dream mentation. State of consciousness was evaluated using the Altered State of Consciousness (5D-ASC) questionnaire. RESULTS: LSD, compared with placebo, significantly increased cognitive bizarreness (p < 0.001). The LSD-induced increase in cognitive bizarreness was positively correlated with the LSD-induced loss of self-boundaries and cognitive control (p < 0.05). Both LSD-induced increases in cognitive bizarreness and changes in state of consciousness were fully blocked by ketanserin. CONCLUSIONS: LSD produced mental imagery similar to dreaming, primarily via activation of the 5-HT2A receptor and in relation to loss of self-boundaries and cognitive control. Future psychopharmacological studies should assess the differential contribution of the D2/D1 and 5-HT1A receptors to cognitive bizarreness. More... »
PAGES2031-2046
http://scigraph.springernature.com/pub.10.1007/s00213-017-4610-0
DOIhttp://dx.doi.org/10.1007/s00213-017-4610-0
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1084517384
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/28386699
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1701",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Psychology",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/17",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Psychology and Cognitive Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Dopamine",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Healthy Volunteers",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Ketanserin",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Lysergic Acid Diethylamide",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Receptor, Serotonin, 5-HT1A",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Receptor, Serotonin, 5-HT2A",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Receptors, Serotonin",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Serotonin",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Serotonin 5-HT2 Receptor Antagonists",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "University of Zurich",
"id": "https://www.grid.ac/institutes/grid.7400.3",
"name": [
"Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, Zurich, Switzerland",
"Neuropsychopharmacology and Brain Imaging, Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, Lenggstrasse 31, 8032, Zurich, Switzerland"
],
"type": "Organization"
},
"familyName": "Kraehenmann",
"givenName": "Rainer",
"id": "sg:person.01055303234.23",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01055303234.23"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Ulm",
"id": "https://www.grid.ac/institutes/grid.6582.9",
"name": [
"Department of Psychosomatic Medicine and Psychotherapy, University of Ulm, Ulm, Germany"
],
"type": "Organization"
},
"familyName": "Pokorny",
"givenName": "Dan",
"id": "sg:person.01170325037.17",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01170325037.17"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Zurich",
"id": "https://www.grid.ac/institutes/grid.7400.3",
"name": [
"Neuropsychopharmacology and Brain Imaging, Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, Lenggstrasse 31, 8032, Zurich, Switzerland"
],
"type": "Organization"
},
"familyName": "Vollenweider",
"givenName": "Leonie",
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Zurich",
"id": "https://www.grid.ac/institutes/grid.7400.3",
"name": [
"Neuropsychopharmacology and Brain Imaging, Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, Lenggstrasse 31, 8032, Zurich, Switzerland"
],
"type": "Organization"
},
"familyName": "Preller",
"givenName": "Katrin H.",
"id": "sg:person.01014212350.89",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014212350.89"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Zurich",
"id": "https://www.grid.ac/institutes/grid.7400.3",
"name": [
"Neuropsychopharmacology and Brain Imaging, Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, Lenggstrasse 31, 8032, Zurich, Switzerland"
],
"type": "Organization"
},
"familyName": "Pokorny",
"givenName": "Thomas",
"id": "sg:person.01304115002.24",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01304115002.24"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Zurich",
"id": "https://www.grid.ac/institutes/grid.7400.3",
"name": [
"Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, Zurich, Switzerland"
],
"type": "Organization"
},
"familyName": "Seifritz",
"givenName": "Erich",
"id": "sg:person.01125014446.41",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01125014446.41"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Zurich",
"id": "https://www.grid.ac/institutes/grid.7400.3",
"name": [
"Neuropsychopharmacology and Brain Imaging, Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, Lenggstrasse 31, 8032, Zurich, Switzerland"
],
"type": "Organization"
},
"familyName": "Vollenweider",
"givenName": "Franz X.",
"id": "sg:person.01076746772.41",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01076746772.41"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1007/s002130050740",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000417767",
"https://doi.org/10.1007/s002130050740"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1017/s0140525x00003988",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002434708"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1016/s0893-133x(96)00246-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002533385",
"https://doi.org/10.1016/s0893-133x(96)00246-1"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nn.3719",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002808680",
"https://doi.org/10.1038/nn.3719"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1080/02791072.2016.1234090",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1003536951"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/cercor/bhg128",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006209373"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0013-4694(66)90037-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1007333661"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0013-4694(66)90037-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1007333661"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/archneurol.2010.35",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1007446911"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.3389/fpsyg.2014.00255",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1008277529"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/1053-8100(92)90059-j",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1008663673"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/hbm.22833",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009051265"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.1518377113",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009321591"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00005053-195503000-00010",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009688292"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00005053-195503000-00010",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009688292"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1046/j.1365-2869.2001.00249.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010764705"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1371/journal.pone.0014074",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011076356"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.concog.2012.03.009",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014094678"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.euroneuro.2016.01.005",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014113875"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00213-009-1718-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014729289",
"https://doi.org/10.1007/s00213-009-1718-x"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00213-009-1718-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014729289",
"https://doi.org/10.1007/s00213-009-1718-x"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00213-009-1718-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014729289",
"https://doi.org/10.1007/s00213-009-1718-x"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/383163a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015220584",
"https://doi.org/10.1038/383163a0"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/hbm.21381",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015803967"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1080/02791072.2012.703099",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016733297"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/archpsyc.1971.01750070052006",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017024979"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.bbr.2014.07.016",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017030273"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.pharmthera.2003.11.002",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018151767"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00005053-195905000-00004",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019068175"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00005053-195905000-00004",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019068175"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature02223",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020116354",
"https://doi.org/10.1038/nature02223"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature02223",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020116354",
"https://doi.org/10.1038/nature02223"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.phrs.2016.08.022",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020300568"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf02245186",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020939272",
"https://doi.org/10.1007/bf02245186"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf02245186",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020939272",
"https://doi.org/10.1007/bf02245186"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0149-7634(78)90007-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023216369"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0149-7634(78)90007-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023216369"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00607573",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023623067",
"https://doi.org/10.1007/bf00607573"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00607573",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023623067",
"https://doi.org/10.1007/bf00607573"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.neuropharm.2011.01.017",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025048253"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.biopsych.2014.11.015",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025342125"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1159/000431291",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025481708"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/hbm.23224",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026261974"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/978-3-7643-8561-3_12",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026658696",
"https://doi.org/10.1007/978-3-7643-8561-3_12"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/978-3-7643-8561-3_12",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026658696",
"https://doi.org/10.1007/978-3-7643-8561-3_12"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1162/089976602317250861",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026843608"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.3758/s13421-012-0256-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027419862",
"https://doi.org/10.3758/s13421-012-0256-7"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1098/rsos.160201",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027484634"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00001756-199812010-00024",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027664489"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/00001756-199812010-00024",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027664489"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0006-3223(95)00418-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027885096"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.euroneuro.2016.03.012",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028322016"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0306-4522(91)90128-b",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029287954"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0306-4522(91)90128-b",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029287954"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrn2716",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029607415",
"https://doi.org/10.1038/nrn2716"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrn2716",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029607415",
"https://doi.org/10.1038/nrn2716"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.neuropsychologia.2016.04.005",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1031100570"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.psychres.2011.02.023",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1031326781"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/bs.3830150402",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032088996"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.neuron.2007.01.008",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032964503"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0361-9230(01)00646-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033154416"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00213-015-4026-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034260809",
"https://doi.org/10.1007/s00213-015-4026-7"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/npp.2009.176",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034351638",
"https://doi.org/10.1038/npp.2009.176"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/npp.2009.176",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034351638",
"https://doi.org/10.1038/npp.2009.176"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1523/jneurosci.3007-12.2013",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034418860"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00213-005-2183-9",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034550352",
"https://doi.org/10.1007/s00213-005-2183-9"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00213-005-2183-9",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034550352",
"https://doi.org/10.1007/s00213-005-2183-9"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1755-5949.2008.00059.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035147328"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf02247474",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035223090",
"https://doi.org/10.1007/bf02247474"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf02247474",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035223090",
"https://doi.org/10.1007/bf02247474"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.neuroscience.2006.02.082",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035242004"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.pbb.2007.06.001",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035276627"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1345/aph.18150",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036529327"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1345/aph.18150",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036529327"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1523/jneurosci.5202-13.2014",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037201053"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.90.5.2078",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037889194"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/schbul/sbm116",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038002646"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00336965",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039022743",
"https://doi.org/10.1007/bf00336965"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1080/23273798.2016.1217030",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039597880"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0024-3205(98)00262-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040023517"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1469-8986.2003.00146.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040267610"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1037/h0094373",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041210182"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/0269881110382466",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041554589"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/0269881110382466",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041554589"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1098/rsif.2014.0873",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042135235"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/schbul/9.1.73",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042149718"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.3389/fpsyg.2013.00408",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042183971"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.pnpbp.2003.09.010",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043328229"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/hbm.22562",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043430667"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/pgmj.52.603.26",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043524327"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1136/pgmj.52.603.26",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043524327"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1162/089892905774597191",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043683067"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1162/089892905774597191",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043683067"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/ijnp/pyv072",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043690833"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/brain/120.7.1173",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043695340"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/archpsyc.1960.03590090042008",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044831612"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1037/10546-022",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045453673"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/archpsyc.1969.01740190097014",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046490156"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1080/00223980.1955.9916156",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046813390"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/0276236615572594",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046877460"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/0276236615572594",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046877460"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1006/ccog.1994.1007",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1047448915"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1080/17588921003731578",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049902376"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.tics.2009.12.001",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050060453"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/npp.2011.228",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050127220",
"https://doi.org/10.1038/npp.2011.228"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1038/jcbfm.2014.68",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050795348"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1038/jcbfm.2014.68",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050795348"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0166-4328(96)00081-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1051371524"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1523/jneurosci.2063-13.2013",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1051627166"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1159/000437210",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052823697"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/0269881108091597",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1053825095"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/0269881108091597",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1053825095"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/0269881108093587",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1054005904"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1177/0269881108093587",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1054005904"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1068/p210637",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1058163204"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1068/p210637",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1058163204"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/brain/101.1.83",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1059437228"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1192/bjp.100.419.491",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064159927"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1192/bjp.100.419.508",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064159928"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1192/bjp.103.431.332",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064160213"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1192/bjp.120.555.159",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064164712"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.cub.2016.12.030",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1074221497"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.cub.2016.12.030",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1074221497"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1075040496",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1076465211",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1076656060",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1076878192",
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/sleep/1.1.97",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1078578695"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1078877077",
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1176/appi.psychotherapy.1969.23.1.4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1080174617"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1080268520",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1080590621",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1080922223",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1081107598",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1081558047",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1082149621",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1082476759",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1083371524",
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.7287/peerj.preprints.1202v1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1107343555"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.7287/peerj.preprints.1202v1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1107343555"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.7287/peerj.preprints.1202v1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1107343555"
],
"type": "CreativeWork"
}
],
"datePublished": "2017-07",
"datePublishedReg": "2017-07-01",
"description": "RATIONALE: Accumulating evidence indicates that the mixed serotonin and dopamine receptor agonist lysergic acid diethylamide (LSD) induces an altered state of consciousness that resembles dreaming.\nOBJECTIVES: This study aimed to test the hypotheses that LSD produces dreamlike waking imagery and that this imagery depends on 5-HT2A receptor activation and is related to subjective drug effects.\nMETHODS: Twenty-five healthy subjects performed an audiorecorded guided mental imagery task 7\u00a0h after drug administration during three drug conditions: placebo, LSD (100\u00a0mcg orally) and LSD together with the 5-HT2A receptor antagonist ketanserin (40\u00a0mg orally). Cognitive bizarreness of guided mental imagery reports was quantified as a standardised formal measure of dream mentation. State of consciousness was evaluated using the Altered State of Consciousness (5D-ASC) questionnaire.\nRESULTS: LSD, compared with placebo, significantly increased cognitive bizarreness (p\u00a0<\u00a00.001). The LSD-induced increase in cognitive bizarreness was positively correlated with the LSD-induced loss of self-boundaries and cognitive control (p\u00a0<\u00a00.05). Both LSD-induced increases in cognitive bizarreness and changes in state of consciousness were fully blocked by ketanserin.\nCONCLUSIONS: LSD produced mental imagery similar to dreaming, primarily via activation of the 5-HT2A receptor and in relation to loss of self-boundaries and cognitive control. Future psychopharmacological studies should assess the differential contribution of the D2/D1 and 5-HT1A receptors to cognitive bizarreness.",
"genre": "research_article",
"id": "sg:pub.10.1007/s00213-017-4610-0",
"inLanguage": [
"en"
],
"isAccessibleForFree": true,
"isFundedItemOf": [
{
"id": "sg:grant.5240115",
"type": "MonetaryGrant"
}
],
"isPartOf": [
{
"id": "sg:journal.1085440",
"issn": [
"0033-3158",
"1432-2072"
],
"name": "Psychopharmacology",
"type": "Periodical"
},
{
"issueNumber": "13",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "234"
}
],
"name": "Dreamlike effects of LSD on waking imagery in humans depend on serotonin 2A receptor activation",
"pagination": "2031-2046",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"74172ae144d66053c1592e44e3707e5bd91187d85633310994fbc64bf7467f54"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"28386699"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"7608025"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s00213-017-4610-0"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1084517384"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s00213-017-4610-0",
"https://app.dimensions.ai/details/publication/pub.1084517384"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-11T10:01",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000347_0000000347/records_89819_00000002.jsonl",
"type": "ScholarlyArticle",
"url": "https://link.springer.com/10.1007%2Fs00213-017-4610-0"
}
]Download the RDF metadata as:Â json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00213-017-4610-0'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00213-017-4610-0'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00213-017-4610-0'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00213-017-4610-0'
This table displays all metadata directly associated to this object as RDF triples.
499 TRIPLES
21 PREDICATES
152 URIs
31 LITERALS
19 BLANK NODES