Thalamic glutamate decreases with cigarette smoking View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2014-07

AUTHORS

Joseph O’Neill, Marc C. Tobias, Matthew Hudkins, Eugene Y. Oh, Gerhard S. Hellemann, Erika L. Nurmi, Edythe D. London

ABSTRACT

RATIONALE: Findings from animal studies and human PET imaging indicate that nicotine and cigarette smoking affect glutamate (Glu) and related neurochemical markers in the brain and imply that smoking reduces extracellular Glu. As Glu release is mediated by nicotinic acetylcholine receptors (nAChRs), which are present at high concentrations in the thalamus, we examined the effects of smoking on thalamic Glu. OBJECTIVE: To determine the effects of tobacco smoking on thalamic glutamate levels. METHODS: Thalamic Glu levels were measured in vivo in 18 smokers and 16 nonsmokers using proton magnetic resonance spectroscopic imaging ((1)H MRSI) at 1.5 T. RESULTS: Mean Glu levels did not differ significantly between the subject groups. However, within smokers, Glu levels were negatively correlated with self-reports of both cigarettes/day over the last 30 days (r = -0.64, p = 0.006) and pack-years of smoking (r = -0.66, p = 0.005). CONCLUSIONS: Consistent with expectations based on preclinical studies, within smokers, cigarettes/day and pack-years are associated with reduced Glu in thalamus, a brain region rich in nAchRs. These results encourage work on candidate glutamatergic therapies for smoking cessation and suggest a noninvasive metric for their action in the brain. More... »

PAGES

2717-2724

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00213-014-3441-5

DOI

http://dx.doi.org/10.1007/s00213-014-3441-5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1050651083

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24535652


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1117", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Public Health and Health Services", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Case-Control Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Glutamic Acid", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Proton Magnetic Resonance Spectroscopy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Receptors, Nicotinic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Smoking", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Thalamus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Time Factors", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of California Los Angeles", 
          "id": "https://www.grid.ac/institutes/grid.19006.3e", 
          "name": [
            "Division of Child & Adolescent Psychiatry, UCLA Semel Institute for Neuroscience, 760 Westwood Plaza, Box 175919, 90024-1759, Los Angeles, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "O\u2019Neill", 
        "givenName": "Joseph", 
        "id": "sg:person.0643454211.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0643454211.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of California Los Angeles", 
          "id": "https://www.grid.ac/institutes/grid.19006.3e", 
          "name": [
            "Division of Child & Adolescent Psychiatry, UCLA Semel Institute for Neuroscience, 760 Westwood Plaza, Box 175919, 90024-1759, Los Angeles, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tobias", 
        "givenName": "Marc C.", 
        "id": "sg:person.01333464433.65", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01333464433.65"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of California Los Angeles", 
          "id": "https://www.grid.ac/institutes/grid.19006.3e", 
          "name": [
            "Division of Child & Adolescent Psychiatry, UCLA Semel Institute for Neuroscience, 760 Westwood Plaza, Box 175919, 90024-1759, Los Angeles, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hudkins", 
        "givenName": "Matthew", 
        "id": "sg:person.01217236033.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01217236033.12"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of California Los Angeles", 
          "id": "https://www.grid.ac/institutes/grid.19006.3e", 
          "name": [
            "Department of Psychiatry and Biobehavioral Sciences, UCLA Semel Institute for Neuroscience, Los Angeles, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Oh", 
        "givenName": "Eugene Y.", 
        "id": "sg:person.01300542077.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01300542077.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of California Los Angeles", 
          "id": "https://www.grid.ac/institutes/grid.19006.3e", 
          "name": [
            "Biostatistics Core, UCLA Semel Institute for Neuroscience, Los Angeles, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hellemann", 
        "givenName": "Gerhard S.", 
        "id": "sg:person.01127577053.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01127577053.05"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of California Los Angeles", 
          "id": "https://www.grid.ac/institutes/grid.19006.3e", 
          "name": [
            "Division of Child & Adolescent Psychiatry, UCLA Semel Institute for Neuroscience, 760 Westwood Plaza, Box 175919, 90024-1759, Los Angeles, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nurmi", 
        "givenName": "Erika L.", 
        "id": "sg:person.0720217051.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0720217051.81"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of California Los Angeles", 
          "id": "https://www.grid.ac/institutes/grid.19006.3e", 
          "name": [
            "Department of Psychiatry and Biobehavioral Sciences, UCLA Semel Institute for Neuroscience, Los Angeles, CA, USA", 
            "UCLA Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, Los Angeles, CA, USA", 
            "UCLA Brain Research Institute, David Geffen School of Medicine, 90024, Los Angeles, CA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "London", 
        "givenName": "Edythe D.", 
        "id": "sg:person.01371250122.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01371250122.51"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/j.bcp.2009.04.019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002786264"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.0022-3042.2002.00805.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003069920"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrn2515", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005189553", 
          "https://doi.org/10.1038/nrn2515"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrn2515", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005189553", 
          "https://doi.org/10.1038/nrn2515"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1530-0277.2006.00060.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006113903"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1530-0277.2006.00060.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006113903"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/nbm.1363", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006959439"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-4679(198511)41:6<820::aid-jclp2270410616>3.0.co;2-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008966449"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3349/ymj.2008.49.2.175", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009453787"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/mrm.20350", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009893544"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.pscychresns.2007.04.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013167235"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.pscychresns.2003.10.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014433851"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/nbm.698", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017303756"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nn1069", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017871287", 
          "https://doi.org/10.1038/nn1069"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nn1069", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017871287", 
          "https://doi.org/10.1038/nn1069"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/nimg.1995.1012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018670682"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1460-9568.2006.05050.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020767953"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1523/jneurosci.2808-07.2007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022220467"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0028-3932(71)90067-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022259601"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neuropharm.2005.01.030", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022417807"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0197-0186(94)90055-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024903118"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0197-0186(94)90055-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024903118"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biopsych.2004.09.021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027894624"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12031-009-9232-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029095138", 
          "https://doi.org/10.1007/s12031-009-9232-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12031-009-9232-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029095138", 
          "https://doi.org/10.1007/s12031-009-9232-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/npp.2008.58", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030268943", 
          "https://doi.org/10.1038/npp.2008.58"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biopsych.2005.06.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030438179"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biopsych.2005.06.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030438179"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ar.1058", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033418378"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1210984110", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037757438"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005053-198001000-00006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038484401"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005053-198001000-00006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038484401"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1359-6446(03)02890-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039224542"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00127-012-0644-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039626317", 
          "https://doi.org/10.1007/s00127-012-0644-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biopsych.2008.10.040", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042311490"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/mrm.20007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043093298"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1523/jneurosci.1766-07.2007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043183535"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neuroimage.2011.02.046", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045445988"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.alc.0000148112.92525.ac", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045609721"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.alc.0000148112.92525.ac", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045609721"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1460-9568.1994.tb00550.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046113436"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1460-9568.1994.tb00550.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046113436"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/syn.20693", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046578089"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/syn.20693", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046578089"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.schres.2011.07.011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050267066"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0166-2236(99)01445-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052560869"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/mrm.21287", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052708345"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jm980233p", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055958854"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jm980233p", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055958854"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-2007-970144", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057502907"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ntr/nts120", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059944033"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074701645", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1523/jneurosci.23-08-03531.2003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1075276317"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078463615", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078588071", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2014-07", 
    "datePublishedReg": "2014-07-01", 
    "description": "RATIONALE: Findings from animal studies and human PET imaging indicate that nicotine and cigarette smoking affect glutamate (Glu) and related neurochemical markers in the brain and imply that smoking reduces extracellular Glu. As Glu release is mediated by nicotinic acetylcholine receptors (nAChRs), which are present at high concentrations in the thalamus, we examined the effects of smoking on thalamic Glu.\nOBJECTIVE: To determine the effects of tobacco smoking on thalamic glutamate levels.\nMETHODS: Thalamic Glu levels were measured in vivo in 18 smokers and 16 nonsmokers using proton magnetic resonance spectroscopic imaging ((1)H MRSI) at 1.5\u00a0T.\nRESULTS: Mean Glu levels did not differ significantly between the subject groups. However, within smokers, Glu levels were negatively correlated with self-reports of both cigarettes/day over the last 30\u00a0days (r\u2009=\u2009-0.64, p\u2009=\u20090.006) and pack-years of smoking (r\u2009=\u2009-0.66, p\u2009=\u20090.005).\nCONCLUSIONS: Consistent with expectations based on preclinical studies, within smokers, cigarettes/day and pack-years are associated with reduced Glu in thalamus, a brain region rich in nAchRs. These results encourage work on candidate glutamatergic therapies for smoking cessation and suggest a noninvasive metric for their action in the brain.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00213-014-3441-5", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2420281", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2685436", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2606920", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2424019", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2570549", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2437750", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2486131", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1085440", 
        "issn": [
          "0033-3158", 
          "1432-2072"
        ], 
        "name": "Psychopharmacology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "13", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "231"
      }
    ], 
    "name": "Thalamic glutamate decreases with cigarette smoking", 
    "pagination": "2717-2724", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "f148cbfdd63739cde7296f47cef44f2e81427c0e3f8868d2244a274507ad99b5"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "24535652"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "7608025"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00213-014-3441-5"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1050651083"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00213-014-3441-5", 
      "https://app.dimensions.ai/details/publication/pub.1050651083"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T14:11", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8660_00000516.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs00213-014-3441-5"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00213-014-3441-5'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00213-014-3441-5'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00213-014-3441-5'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00213-014-3441-5'


 

This table displays all metadata directly associated to this object as RDF triples.

307 TRIPLES      21 PREDICATES      84 URIs      32 LITERALS      20 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00213-014-3441-5 schema:about N116e94d397ef437ea5e746c465f2e9e7
2 N1ae415c42bcb4d4cb60f0af6b67a2657
3 N1f958c61d2204660a6c09932a7d80745
4 N3e30375821fc4e58aa27c76883e5434c
5 N499e7133c6014750b65004428ba97251
6 N4e479e6fb7eb4073b90052e779a31db5
7 N5a84d1246a654d30b5683b80df276205
8 Na49c338fa44e4e648c14bafac3108fb8
9 Nb469dddfcfc146eba9647f2ae6be587b
10 Nbaff06683a444da4aec76eb42cf400aa
11 Nd555ef034d054a23a8f84370a3c2f5fe
12 anzsrc-for:11
13 anzsrc-for:1117
14 schema:author N11b3366323cc4ece82348523266b55f1
15 schema:citation sg:pub.10.1007/s00127-012-0644-0
16 sg:pub.10.1007/s12031-009-9232-5
17 sg:pub.10.1038/nn1069
18 sg:pub.10.1038/npp.2008.58
19 sg:pub.10.1038/nrn2515
20 https://app.dimensions.ai/details/publication/pub.1074701645
21 https://app.dimensions.ai/details/publication/pub.1078463615
22 https://app.dimensions.ai/details/publication/pub.1078588071
23 https://doi.org/10.1002/1097-4679(198511)41:6<820::aid-jclp2270410616>3.0.co;2-x
24 https://doi.org/10.1002/ar.1058
25 https://doi.org/10.1002/mrm.20007
26 https://doi.org/10.1002/mrm.20350
27 https://doi.org/10.1002/mrm.21287
28 https://doi.org/10.1002/nbm.1363
29 https://doi.org/10.1002/nbm.698
30 https://doi.org/10.1002/syn.20693
31 https://doi.org/10.1006/nimg.1995.1012
32 https://doi.org/10.1016/0028-3932(71)90067-4
33 https://doi.org/10.1016/0197-0186(94)90055-8
34 https://doi.org/10.1016/j.bcp.2009.04.019
35 https://doi.org/10.1016/j.biopsych.2004.09.021
36 https://doi.org/10.1016/j.biopsych.2005.06.009
37 https://doi.org/10.1016/j.biopsych.2008.10.040
38 https://doi.org/10.1016/j.neuroimage.2011.02.046
39 https://doi.org/10.1016/j.neuropharm.2005.01.030
40 https://doi.org/10.1016/j.pscychresns.2003.10.001
41 https://doi.org/10.1016/j.pscychresns.2007.04.003
42 https://doi.org/10.1016/j.schres.2011.07.011
43 https://doi.org/10.1016/s0166-2236(99)01445-9
44 https://doi.org/10.1016/s1359-6446(03)02890-3
45 https://doi.org/10.1021/jm980233p
46 https://doi.org/10.1046/j.0022-3042.2002.00805.x
47 https://doi.org/10.1055/s-2007-970144
48 https://doi.org/10.1073/pnas.1210984110
49 https://doi.org/10.1093/ntr/nts120
50 https://doi.org/10.1097/00005053-198001000-00006
51 https://doi.org/10.1097/01.alc.0000148112.92525.ac
52 https://doi.org/10.1111/j.1460-9568.1994.tb00550.x
53 https://doi.org/10.1111/j.1460-9568.2006.05050.x
54 https://doi.org/10.1111/j.1530-0277.2006.00060.x
55 https://doi.org/10.1523/jneurosci.1766-07.2007
56 https://doi.org/10.1523/jneurosci.23-08-03531.2003
57 https://doi.org/10.1523/jneurosci.2808-07.2007
58 https://doi.org/10.3349/ymj.2008.49.2.175
59 schema:datePublished 2014-07
60 schema:datePublishedReg 2014-07-01
61 schema:description RATIONALE: Findings from animal studies and human PET imaging indicate that nicotine and cigarette smoking affect glutamate (Glu) and related neurochemical markers in the brain and imply that smoking reduces extracellular Glu. As Glu release is mediated by nicotinic acetylcholine receptors (nAChRs), which are present at high concentrations in the thalamus, we examined the effects of smoking on thalamic Glu. OBJECTIVE: To determine the effects of tobacco smoking on thalamic glutamate levels. METHODS: Thalamic Glu levels were measured in vivo in 18 smokers and 16 nonsmokers using proton magnetic resonance spectroscopic imaging ((1)H MRSI) at 1.5 T. RESULTS: Mean Glu levels did not differ significantly between the subject groups. However, within smokers, Glu levels were negatively correlated with self-reports of both cigarettes/day over the last 30 days (r = -0.64, p = 0.006) and pack-years of smoking (r = -0.66, p = 0.005). CONCLUSIONS: Consistent with expectations based on preclinical studies, within smokers, cigarettes/day and pack-years are associated with reduced Glu in thalamus, a brain region rich in nAchRs. These results encourage work on candidate glutamatergic therapies for smoking cessation and suggest a noninvasive metric for their action in the brain.
62 schema:genre research_article
63 schema:inLanguage en
64 schema:isAccessibleForFree true
65 schema:isPartOf Na19911de3f3d40aba6afcc28e56d250e
66 Ncf5d6bf4ddd740ae950cd371d340b3cc
67 sg:journal.1085440
68 schema:name Thalamic glutamate decreases with cigarette smoking
69 schema:pagination 2717-2724
70 schema:productId N0046b9b4357646318829331245668715
71 N13e4c7c5cb2747c7b1dda090db147618
72 N3c38443921464951901c551f67634463
73 N41855aa6c01e41ee821754b7259d6448
74 Na131533adbf845c688841edae2bdc70f
75 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050651083
76 https://doi.org/10.1007/s00213-014-3441-5
77 schema:sdDatePublished 2019-04-10T14:11
78 schema:sdLicense https://scigraph.springernature.com/explorer/license/
79 schema:sdPublisher N20a38c85dbc04629bcbb5a289e8063a7
80 schema:url http://link.springer.com/10.1007%2Fs00213-014-3441-5
81 sgo:license sg:explorer/license/
82 sgo:sdDataset articles
83 rdf:type schema:ScholarlyArticle
84 N0046b9b4357646318829331245668715 schema:name nlm_unique_id
85 schema:value 7608025
86 rdf:type schema:PropertyValue
87 N0d9d2f82ffa74ac7a80b12c4e0c7c4d8 rdf:first sg:person.01127577053.05
88 rdf:rest N17aae4bfeeba4cd0a8a01444c8dcb8fe
89 N116e94d397ef437ea5e746c465f2e9e7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name Humans
91 rdf:type schema:DefinedTerm
92 N11b3366323cc4ece82348523266b55f1 rdf:first sg:person.0643454211.17
93 rdf:rest N5f9d35f99902444286db91b76958ec65
94 N13e4c7c5cb2747c7b1dda090db147618 schema:name doi
95 schema:value 10.1007/s00213-014-3441-5
96 rdf:type schema:PropertyValue
97 N17aae4bfeeba4cd0a8a01444c8dcb8fe rdf:first sg:person.0720217051.81
98 rdf:rest N58b632db383840529ec85d56ccc262fe
99 N1ae415c42bcb4d4cb60f0af6b67a2657 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
100 schema:name Adult
101 rdf:type schema:DefinedTerm
102 N1f958c61d2204660a6c09932a7d80745 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Smoking
104 rdf:type schema:DefinedTerm
105 N20a38c85dbc04629bcbb5a289e8063a7 schema:name Springer Nature - SN SciGraph project
106 rdf:type schema:Organization
107 N3c38443921464951901c551f67634463 schema:name readcube_id
108 schema:value f148cbfdd63739cde7296f47cef44f2e81427c0e3f8868d2244a274507ad99b5
109 rdf:type schema:PropertyValue
110 N3e30375821fc4e58aa27c76883e5434c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Glutamic Acid
112 rdf:type schema:DefinedTerm
113 N41855aa6c01e41ee821754b7259d6448 schema:name dimensions_id
114 schema:value pub.1050651083
115 rdf:type schema:PropertyValue
116 N499e7133c6014750b65004428ba97251 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Thalamus
118 rdf:type schema:DefinedTerm
119 N4e479e6fb7eb4073b90052e779a31db5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Proton Magnetic Resonance Spectroscopy
121 rdf:type schema:DefinedTerm
122 N4fb02ba0e82b4dcdba8c23a6ce3054a4 rdf:first sg:person.01217236033.12
123 rdf:rest Nb4a4cf905fb64becad26155ef53c33a2
124 N58b632db383840529ec85d56ccc262fe rdf:first sg:person.01371250122.51
125 rdf:rest rdf:nil
126 N5a84d1246a654d30b5683b80df276205 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Time Factors
128 rdf:type schema:DefinedTerm
129 N5f9d35f99902444286db91b76958ec65 rdf:first sg:person.01333464433.65
130 rdf:rest N4fb02ba0e82b4dcdba8c23a6ce3054a4
131 Na131533adbf845c688841edae2bdc70f schema:name pubmed_id
132 schema:value 24535652
133 rdf:type schema:PropertyValue
134 Na19911de3f3d40aba6afcc28e56d250e schema:issueNumber 13
135 rdf:type schema:PublicationIssue
136 Na49c338fa44e4e648c14bafac3108fb8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Case-Control Studies
138 rdf:type schema:DefinedTerm
139 Nb469dddfcfc146eba9647f2ae6be587b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Receptors, Nicotinic
141 rdf:type schema:DefinedTerm
142 Nb4a4cf905fb64becad26155ef53c33a2 rdf:first sg:person.01300542077.15
143 rdf:rest N0d9d2f82ffa74ac7a80b12c4e0c7c4d8
144 Nbaff06683a444da4aec76eb42cf400aa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Female
146 rdf:type schema:DefinedTerm
147 Ncf5d6bf4ddd740ae950cd371d340b3cc schema:volumeNumber 231
148 rdf:type schema:PublicationVolume
149 Nd555ef034d054a23a8f84370a3c2f5fe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
150 schema:name Male
151 rdf:type schema:DefinedTerm
152 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
153 schema:name Medical and Health Sciences
154 rdf:type schema:DefinedTerm
155 anzsrc-for:1117 schema:inDefinedTermSet anzsrc-for:
156 schema:name Public Health and Health Services
157 rdf:type schema:DefinedTerm
158 sg:grant.2420281 http://pending.schema.org/fundedItem sg:pub.10.1007/s00213-014-3441-5
159 rdf:type schema:MonetaryGrant
160 sg:grant.2424019 http://pending.schema.org/fundedItem sg:pub.10.1007/s00213-014-3441-5
161 rdf:type schema:MonetaryGrant
162 sg:grant.2437750 http://pending.schema.org/fundedItem sg:pub.10.1007/s00213-014-3441-5
163 rdf:type schema:MonetaryGrant
164 sg:grant.2486131 http://pending.schema.org/fundedItem sg:pub.10.1007/s00213-014-3441-5
165 rdf:type schema:MonetaryGrant
166 sg:grant.2570549 http://pending.schema.org/fundedItem sg:pub.10.1007/s00213-014-3441-5
167 rdf:type schema:MonetaryGrant
168 sg:grant.2606920 http://pending.schema.org/fundedItem sg:pub.10.1007/s00213-014-3441-5
169 rdf:type schema:MonetaryGrant
170 sg:grant.2685436 http://pending.schema.org/fundedItem sg:pub.10.1007/s00213-014-3441-5
171 rdf:type schema:MonetaryGrant
172 sg:journal.1085440 schema:issn 0033-3158
173 1432-2072
174 schema:name Psychopharmacology
175 rdf:type schema:Periodical
176 sg:person.01127577053.05 schema:affiliation https://www.grid.ac/institutes/grid.19006.3e
177 schema:familyName Hellemann
178 schema:givenName Gerhard S.
179 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01127577053.05
180 rdf:type schema:Person
181 sg:person.01217236033.12 schema:affiliation https://www.grid.ac/institutes/grid.19006.3e
182 schema:familyName Hudkins
183 schema:givenName Matthew
184 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01217236033.12
185 rdf:type schema:Person
186 sg:person.01300542077.15 schema:affiliation https://www.grid.ac/institutes/grid.19006.3e
187 schema:familyName Oh
188 schema:givenName Eugene Y.
189 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01300542077.15
190 rdf:type schema:Person
191 sg:person.01333464433.65 schema:affiliation https://www.grid.ac/institutes/grid.19006.3e
192 schema:familyName Tobias
193 schema:givenName Marc C.
194 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01333464433.65
195 rdf:type schema:Person
196 sg:person.01371250122.51 schema:affiliation https://www.grid.ac/institutes/grid.19006.3e
197 schema:familyName London
198 schema:givenName Edythe D.
199 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01371250122.51
200 rdf:type schema:Person
201 sg:person.0643454211.17 schema:affiliation https://www.grid.ac/institutes/grid.19006.3e
202 schema:familyName O’Neill
203 schema:givenName Joseph
204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0643454211.17
205 rdf:type schema:Person
206 sg:person.0720217051.81 schema:affiliation https://www.grid.ac/institutes/grid.19006.3e
207 schema:familyName Nurmi
208 schema:givenName Erika L.
209 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0720217051.81
210 rdf:type schema:Person
211 sg:pub.10.1007/s00127-012-0644-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039626317
212 https://doi.org/10.1007/s00127-012-0644-0
213 rdf:type schema:CreativeWork
214 sg:pub.10.1007/s12031-009-9232-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029095138
215 https://doi.org/10.1007/s12031-009-9232-5
216 rdf:type schema:CreativeWork
217 sg:pub.10.1038/nn1069 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017871287
218 https://doi.org/10.1038/nn1069
219 rdf:type schema:CreativeWork
220 sg:pub.10.1038/npp.2008.58 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030268943
221 https://doi.org/10.1038/npp.2008.58
222 rdf:type schema:CreativeWork
223 sg:pub.10.1038/nrn2515 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005189553
224 https://doi.org/10.1038/nrn2515
225 rdf:type schema:CreativeWork
226 https://app.dimensions.ai/details/publication/pub.1074701645 schema:CreativeWork
227 https://app.dimensions.ai/details/publication/pub.1078463615 schema:CreativeWork
228 https://app.dimensions.ai/details/publication/pub.1078588071 schema:CreativeWork
229 https://doi.org/10.1002/1097-4679(198511)41:6<820::aid-jclp2270410616>3.0.co;2-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1008966449
230 rdf:type schema:CreativeWork
231 https://doi.org/10.1002/ar.1058 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033418378
232 rdf:type schema:CreativeWork
233 https://doi.org/10.1002/mrm.20007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043093298
234 rdf:type schema:CreativeWork
235 https://doi.org/10.1002/mrm.20350 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009893544
236 rdf:type schema:CreativeWork
237 https://doi.org/10.1002/mrm.21287 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052708345
238 rdf:type schema:CreativeWork
239 https://doi.org/10.1002/nbm.1363 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006959439
240 rdf:type schema:CreativeWork
241 https://doi.org/10.1002/nbm.698 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017303756
242 rdf:type schema:CreativeWork
243 https://doi.org/10.1002/syn.20693 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046578089
244 rdf:type schema:CreativeWork
245 https://doi.org/10.1006/nimg.1995.1012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018670682
246 rdf:type schema:CreativeWork
247 https://doi.org/10.1016/0028-3932(71)90067-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022259601
248 rdf:type schema:CreativeWork
249 https://doi.org/10.1016/0197-0186(94)90055-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024903118
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1016/j.bcp.2009.04.019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002786264
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1016/j.biopsych.2004.09.021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027894624
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1016/j.biopsych.2005.06.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030438179
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1016/j.biopsych.2008.10.040 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042311490
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1016/j.neuroimage.2011.02.046 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045445988
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1016/j.neuropharm.2005.01.030 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022417807
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1016/j.pscychresns.2003.10.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014433851
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1016/j.pscychresns.2007.04.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013167235
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1016/j.schres.2011.07.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050267066
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1016/s0166-2236(99)01445-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052560869
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1016/s1359-6446(03)02890-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039224542
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1021/jm980233p schema:sameAs https://app.dimensions.ai/details/publication/pub.1055958854
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1046/j.0022-3042.2002.00805.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1003069920
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1055/s-2007-970144 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057502907
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1073/pnas.1210984110 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037757438
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1093/ntr/nts120 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059944033
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1097/00005053-198001000-00006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038484401
284 rdf:type schema:CreativeWork
285 https://doi.org/10.1097/01.alc.0000148112.92525.ac schema:sameAs https://app.dimensions.ai/details/publication/pub.1045609721
286 rdf:type schema:CreativeWork
287 https://doi.org/10.1111/j.1460-9568.1994.tb00550.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1046113436
288 rdf:type schema:CreativeWork
289 https://doi.org/10.1111/j.1460-9568.2006.05050.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1020767953
290 rdf:type schema:CreativeWork
291 https://doi.org/10.1111/j.1530-0277.2006.00060.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1006113903
292 rdf:type schema:CreativeWork
293 https://doi.org/10.1523/jneurosci.1766-07.2007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043183535
294 rdf:type schema:CreativeWork
295 https://doi.org/10.1523/jneurosci.23-08-03531.2003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1075276317
296 rdf:type schema:CreativeWork
297 https://doi.org/10.1523/jneurosci.2808-07.2007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022220467
298 rdf:type schema:CreativeWork
299 https://doi.org/10.3349/ymj.2008.49.2.175 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009453787
300 rdf:type schema:CreativeWork
301 https://www.grid.ac/institutes/grid.19006.3e schema:alternateName University of California Los Angeles
302 schema:name Biostatistics Core, UCLA Semel Institute for Neuroscience, Los Angeles, CA, USA
303 Department of Psychiatry and Biobehavioral Sciences, UCLA Semel Institute for Neuroscience, Los Angeles, CA, USA
304 Division of Child & Adolescent Psychiatry, UCLA Semel Institute for Neuroscience, 760 Westwood Plaza, Box 175919, 90024-1759, Los Angeles, CA, USA
305 UCLA Brain Research Institute, David Geffen School of Medicine, 90024, Los Angeles, CA, USA
306 UCLA Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, Los Angeles, CA, USA
307 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...