Benefits and safety of dietary protein for bone health—an expert consensus paper endorsed by the European Society for Clinical and ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-05-08

AUTHORS

R. Rizzoli, E. Biver, J.-P. Bonjour, V. Coxam, D. Goltzman, J. A. Kanis, J. Lappe, L. Rejnmark, S. Sahni, C. Weaver, H. Weiler, J.-Y. Reginster

ABSTRACT

A summary of systematic reviews and meta-analyses addressing the benefits and risks of dietary protein intakes for bone health in adults suggests that dietary protein levels even above the current RDA may be beneficial in reducing bone loss and hip fracture risk, provided calcium intakes are adequate. Several systematic reviews and meta-analyses have addressed the benefits and risks of dietary protein intakes for bone health in adults. This narrative review of the literature summarizes and synthesizes recent systematic reviews and meta-analyses and highlights key messages. Adequate supplies of dietary protein are required for optimal bone growth and maintenance of healthy bone. Variation in protein intakes within the “normal” range accounts for 2–4% of BMD variance in adults. In older people with osteoporosis, higher protein intake (≥ 0.8-g/kg body weight/day, i.e., above the current RDA) is associated with higher BMD, a slower rate of bone loss, and reduced risk of hip fracture, provided that dietary calcium intakes are adequate. Intervention with dietary protein supplements attenuate age-related BMD decrease and reduce bone turnover marker levels, together with an increase in IGF-I and a decrease in PTH. There is no evidence that diet-derived acid load is deleterious for bone health. Thus, insufficient dietary protein intakes may be a more severe problem than protein excess in the elderly. Long-term, well-controlled randomized trials are required to further assess the influence of dietary protein intakes on fracture risk. More... »

PAGES

1933-1948

References to SciGraph publications

  • 2003-08-12. The effect of milk supplementation on bone mineral density in postmenopausal Chinese women in Malaysia in OSTEOPOROSIS INTERNATIONAL
  • 2013-06-16. Low iron status as a factor of increased bone resorption and effects of an iron and vitamin D-fortified skimmed milk on bone remodelling in young Spanish women in EUROPEAN JOURNAL OF NUTRITION
  • 2016-01-25. Increased intake of vegetables, but not fruits, may be associated with reduced risk of hip fracture: A meta-analysis in SCIENTIFIC REPORTS
  • 2005-05-11. Short-term effects on bone turnover of replacing milk with cola beverages: a 10-day interventional study in young men in OSTEOPOROSIS INTERNATIONAL
  • 2009-03-19. Evaluation of milk basic protein supplementation on bone density and bone metabolism in Chinese young women in EUROPEAN JOURNAL OF NUTRITION
  • 2007-02-07. Comparative fracture risk in vegetarians and nonvegetarians in EPIC-Oxford in EUROPEAN JOURNAL OF CLINICAL NUTRITION
  • 2012-10-19. European guidance for the diagnosis and management of osteoporosis in postmenopausal women in OSTEOPOROSIS INTERNATIONAL
  • 2011-04-30. Causal assessment of dietary acid load and bone disease: a systematic review & meta-analysis applying Hill's epidemiologic criteria for causality in NUTRITION JOURNAL
  • 2001-06. Diet Acids and Alkalis Influence Calcium Retention in Bone in OSTEOPOROSIS INTERNATIONAL
  • 2007-01-25. Comparative effects of oral aromatic and branched-chain amino acids on urine calcium excretion in humans in OSTEOPOROSIS INTERNATIONAL
  • 2010-01-13. Total body bone mineral content and density during weight loss and maintenance on a low- or recommended-dairy weight-maintenance diet in obese men and women in EUROPEAN JOURNAL OF CLINICAL NUTRITION
  • 2012-05-30. High-calcium, vitamin D fortified milk is effective in improving bone turnover markers and vitamin D status in healthy postmenopausal Chinese women in EUROPEAN JOURNAL OF CLINICAL NUTRITION
  • 2008-10-28. Effects of a multi-component exercise program and calcium–vitamin-D3-fortified milk on bone mineral density in older men: a randomised controlled trial in OSTEOPOROSIS INTERNATIONAL
  • 2014-09-16. Dietary acid load, kidney function, osteoporosis, and risk of fractures in elderly men and women in OSTEOPOROSIS INTERNATIONAL
  • 2015-01-09. The effect of supplementation with alkaline potassium salts on bone metabolism: a meta-analysis in OSTEOPOROSIS INTERNATIONAL
  • 2006-10-18. Milk basic protein increases bone mineral density and improves bone metabolism in healthy young women in OSTEOPOROSIS INTERNATIONAL
  • 2010-01-01. Effect of milk and calcium supplementation on bone density and bone turnover in pregnant Chinese women: a randomized controlled trail in ARCHIVES OF GYNECOLOGY AND OBSTETRICS
  • 2010-05-05. Does dietary protein reduce hip fracture risk in elders? The Framingham osteoporosis study in OSTEOPOROSIS INTERNATIONAL
  • 2011-04-01. Possible site-specific effect of an intervention combining nutrition and lifestyle counselling with consumption of fortified dairy products on bone mass: the Postmenopausal Health Study II in JOURNAL OF BONE AND MINERAL METABOLISM
  • 2005-08-31. A controlled trial of the effect of milk basic protein (MBP) supplementation on bone metabolism in healthy menopausal women in OSTEOPOROSIS INTERNATIONAL
  • 1992-05. A case-control study of hip fracture: evaluation of selected dietary variables and teenage physical activity in OSTEOPOROSIS INTERNATIONAL
  • 2010-12-14. Calcium and vitamin D supplementation through fortified dairy products counterbalances seasonal variations of bone metabolism indices: the Postmenopausal Health Study in EUROPEAN JOURNAL OF NUTRITION
  • 2015-05-22. Associations of protein intake and protein source with bone mineral density and fracture risk: A population-based cohort study in THE JOURNAL OF NUTRITION, HEALTH & AGING
  • 2015-03-16. The Relationship between Dietary Protein Consumption and Risk of Fracture: a subgroup and dose-response meta-analysis of prospective cohort studies in SCIENTIFIC REPORTS
  • 2017-08-19. Effects of Fermented Milk Products on Bone in CALCIFIED TISSUE INTERNATIONAL
  • 2017-01-10. Protein intake and risk of hip fractures in postmenopausal women and men age 50 and older in OSTEOPOROSIS INTERNATIONAL
  • 2012-01-27. Bone mineral density in postmenopausal Chinese women treated with calcium fortification in soymilk and cow's milk in OSTEOPOROSIS INTERNATIONAL
  • 2009-09-15. Phosphate decreases urine calcium and increases calcium balance: A meta-analysis of the osteoporosis acid-ash diet hypothesis in NUTRITION JOURNAL
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00198-018-4534-5

    DOI

    http://dx.doi.org/10.1007/s00198-018-4534-5

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1103878860

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/29740667


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Clinical Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Acid-Base Equilibrium", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Bone Density", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Bone Remodeling", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Calcium, Dietary", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Dietary Proteins", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Osteoporosis", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Osteoporotic Fractures", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Risk Assessment", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Division of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, 1211, Geneva 14, Switzerland", 
              "id": "http://www.grid.ac/institutes/grid.150338.c", 
              "name": [
                "Division of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, 1211, Geneva 14, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Rizzoli", 
            "givenName": "R.", 
            "id": "sg:person.01117504756.04", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01117504756.04"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Division of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, 1211, Geneva 14, Switzerland", 
              "id": "http://www.grid.ac/institutes/grid.150338.c", 
              "name": [
                "Division of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, 1211, Geneva 14, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Biver", 
            "givenName": "E.", 
            "id": "sg:person.01064056326.93", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01064056326.93"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Division of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, 1211, Geneva 14, Switzerland", 
              "id": "http://www.grid.ac/institutes/grid.150338.c", 
              "name": [
                "Division of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, 1211, Geneva 14, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Bonjour", 
            "givenName": "J.-P.", 
            "id": "sg:person.010244741404.52", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010244741404.52"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "INRA, Unit\u00e9 de Nutrition Humaine, CRNH Auvergne, Universit\u00e9 Clermont Auvergne, F-63000, Clermont-Ferrand, France", 
              "id": "http://www.grid.ac/institutes/grid.494717.8", 
              "name": [
                "INRA, Unit\u00e9 de Nutrition Humaine, CRNH Auvergne, Universit\u00e9 Clermont Auvergne, F-63000, Clermont-Ferrand, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Coxam", 
            "givenName": "V.", 
            "id": "sg:person.0772574427.82", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0772574427.82"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "McGill University Health Center, Montreal, Canada", 
              "id": "http://www.grid.ac/institutes/grid.63984.30", 
              "name": [
                "McGill University Health Center, Montreal, Canada"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Goltzman", 
            "givenName": "D.", 
            "id": "sg:person.0654664237.90", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0654664237.90"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Institute for Health and Ageing, Catholic University of Australia, Melbourne, Australia", 
              "id": "http://www.grid.ac/institutes/None", 
              "name": [
                "University of Sheffield, Sheffield, UK", 
                "Institute for Health and Ageing, Catholic University of Australia, Melbourne, Australia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kanis", 
            "givenName": "J. A.", 
            "id": "sg:person.0663427426.32", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0663427426.32"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "College of Nursing, Creighton University, Creighton, NE, USA", 
              "id": "http://www.grid.ac/institutes/grid.254748.8", 
              "name": [
                "College of Nursing, Creighton University, Creighton, NE, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lappe", 
            "givenName": "J.", 
            "id": "sg:person.0714345342.23", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0714345342.23"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Aarhus University Hospital, Aarhus, Denmark", 
              "id": "http://www.grid.ac/institutes/grid.154185.c", 
              "name": [
                "Aarhus University Hospital, Aarhus, Denmark"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Rejnmark", 
            "givenName": "L.", 
            "id": "sg:person.0675133170.01", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0675133170.01"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Hebrew SeniorLife and Harvard Medical School, Institute for Aging Research, Boston, MA, USA", 
              "id": "http://www.grid.ac/institutes/grid.38142.3c", 
              "name": [
                "Hebrew SeniorLife and Harvard Medical School, Institute for Aging Research, Boston, MA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Sahni", 
            "givenName": "S.", 
            "id": "sg:person.01270403025.38", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01270403025.38"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Women\u2019s Global Health Institute, Department of Nutrition Science, Purdue University, Purdue, West Lafayette, IN, USA", 
              "id": "http://www.grid.ac/institutes/grid.169077.e", 
              "name": [
                "Women\u2019s Global Health Institute, Department of Nutrition Science, Purdue University, Purdue, West Lafayette, IN, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Weaver", 
            "givenName": "C.", 
            "id": "sg:person.01201650421.06", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01201650421.06"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "School of Human Nutrition, McGill University, Montreal, QC, Canada", 
              "id": "http://www.grid.ac/institutes/grid.14709.3b", 
              "name": [
                "School of Human Nutrition, McGill University, Montreal, QC, Canada"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Weiler", 
            "givenName": "H.", 
            "id": "sg:person.0633767254.51", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0633767254.51"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Public Health, Epidemiology and Health Economics, University of Li\u00e8ge, Li\u00e8ge, Belgium", 
              "id": "http://www.grid.ac/institutes/grid.4861.b", 
              "name": [
                "Department of Public Health, Epidemiology and Health Economics, University of Li\u00e8ge, Li\u00e8ge, Belgium"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Reginster", 
            "givenName": "J.-Y.", 
            "id": "sg:person.01043351033.16", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01043351033.16"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1007/s00223-017-0317-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1091245119", 
              "https://doi.org/10.1007/s00223-017-0317-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ejcn.2009.156", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050754008", 
              "https://doi.org/10.1038/ejcn.2009.156"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00198-005-2012-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037015139", 
              "https://doi.org/10.1007/s00198-005-2012-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12603-015-0544-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029051322", 
              "https://doi.org/10.1007/s12603-015-0544-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf01623818", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032889900", 
              "https://doi.org/10.1007/bf01623818"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00198-006-0320-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036644381", 
              "https://doi.org/10.1007/s00198-006-0320-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00198-014-2888-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006358462", 
              "https://doi.org/10.1007/s00198-014-2888-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00404-009-1345-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035696652", 
              "https://doi.org/10.1007/s00404-009-1345-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00394-010-0142-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036858365", 
              "https://doi.org/10.1007/s00394-010-0142-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00198-014-3006-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045480358", 
              "https://doi.org/10.1007/s00198-014-3006-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00198-012-2074-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046005055", 
              "https://doi.org/10.1007/s00198-012-2074-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00198-003-1448-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024758573", 
              "https://doi.org/10.1007/s00198-003-1448-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ejcn.2012.54", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048029628", 
              "https://doi.org/10.1038/ejcn.2012.54"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00198-012-1895-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014880500", 
              "https://doi.org/10.1007/s00198-012-1895-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s001980170095", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040028886", 
              "https://doi.org/10.1007/s001980170095"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.ejcn.1602659", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023385536", 
              "https://doi.org/10.1038/sj.ejcn.1602659"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1475-2891-8-41", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035615315", 
              "https://doi.org/10.1186/1475-2891-8-41"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00394-013-0544-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046674445", 
              "https://doi.org/10.1007/s00394-013-0544-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00198-008-0776-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035512079", 
              "https://doi.org/10.1007/s00198-008-0776-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00394-009-0014-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025468953", 
              "https://doi.org/10.1007/s00394-009-0014-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/srep09151", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022532391", 
              "https://doi.org/10.1038/srep09151"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/srep19783", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030185418", 
              "https://doi.org/10.1038/srep19783"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1475-2891-10-41", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005924870", 
              "https://doi.org/10.1186/1475-2891-10-41"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00774-010-0256-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041474477", 
              "https://doi.org/10.1007/s00774-010-0256-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00198-016-3898-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006659375", 
              "https://doi.org/10.1007/s00198-016-3898-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00198-006-0228-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030588485", 
              "https://doi.org/10.1007/s00198-006-0228-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00198-010-1179-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047579321", 
              "https://doi.org/10.1007/s00198-010-1179-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00198-005-1935-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044610711", 
              "https://doi.org/10.1007/s00198-005-1935-z"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2018-05-08", 
        "datePublishedReg": "2018-05-08", 
        "description": "A summary of systematic reviews and meta-analyses addressing the benefits and risks of dietary protein intakes for bone health in adults suggests that dietary protein levels even above the current RDA may be beneficial in reducing bone loss and hip fracture risk, provided calcium intakes are adequate. Several systematic reviews and meta-analyses have addressed the benefits and risks of dietary protein intakes for bone health in adults. This narrative review of the literature summarizes and synthesizes recent systematic reviews and meta-analyses and highlights key messages. Adequate supplies of dietary protein are required for optimal bone growth and maintenance of healthy bone. Variation in protein intakes within the \u201cnormal\u201d range accounts for 2\u20134% of BMD variance in adults. In older people with osteoporosis, higher protein intake (\u2265\u20090.8-g/kg body weight/day, i.e., above the current RDA) is associated with higher BMD, a slower rate of bone loss, and reduced risk of hip fracture, provided that dietary calcium intakes are adequate. Intervention with dietary protein supplements attenuate age-related BMD decrease and reduce bone turnover marker levels, together with an increase in IGF-I and a decrease in PTH. There is no evidence that diet-derived acid load is deleterious for bone health. Thus, insufficient dietary protein intakes may be a more severe problem than protein excess in the elderly. Long-term, well-controlled randomized trials are required to further assess the influence of dietary protein intakes on fracture risk.", 
        "genre": "article", 
        "id": "sg:pub.10.1007/s00198-018-4534-5", 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1100834", 
            "issn": [
              "0937-941X", 
              "1433-2965"
            ], 
            "name": "Osteoporosis International", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "9", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "29"
          }
        ], 
        "keywords": [
          "dietary protein intake", 
          "bone health", 
          "protein intake", 
          "systematic review", 
          "calcium intake", 
          "bone loss", 
          "fracture risk", 
          "insufficient dietary protein intake", 
          "bone turnover marker levels", 
          "expert consensus paper", 
          "dietary calcium intake", 
          "hip fracture risk", 
          "dietary protein", 
          "high protein intake", 
          "International Osteoporosis Foundation", 
          "recent systematic review", 
          "optimal bone growth", 
          "hip fracture", 
          "randomized trials", 
          "BMD decrease", 
          "BMD variance", 
          "marker levels", 
          "current RDA", 
          "higher BMD", 
          "consensus paper", 
          "musculoskeletal diseases", 
          "dietary protein level", 
          "narrative review", 
          "acid load", 
          "healthy bone", 
          "older people", 
          "intake", 
          "European Society", 
          "dietary protein supplement", 
          "protein levels", 
          "bone growth", 
          "risk", 
          "adults", 
          "protein excess", 
          "health", 
          "review", 
          "key messages", 
          "osteoporosis", 
          "osteoarthritis", 
          "IGF", 
          "protein supplement", 
          "PTH", 
          "Clinical", 
          "BMD", 
          "disease", 
          "trials", 
          "adequate supply", 
          "benefits", 
          "intervention", 
          "levels", 
          "bone", 
          "decrease", 
          "protein", 
          "slower rate", 
          "supplements", 
          "fractures", 
          "safety", 
          "loss", 
          "RDA", 
          "evidence", 
          "summary", 
          "severe problems", 
          "rate", 
          "increase", 
          "people", 
          "maintenance", 
          "summarizes", 
          "excess", 
          "variance", 
          "growth", 
          "aspects", 
          "society", 
          "influence", 
          "supply", 
          "load", 
          "variation", 
          "messages", 
          "economical aspects", 
          "problem", 
          "foundation", 
          "account", 
          "paper"
        ], 
        "name": "Benefits and safety of dietary protein for bone health\u2014an expert consensus paper endorsed by the European Society for Clinical and Economical Aspects of Osteopororosis, Osteoarthritis, and Musculoskeletal Diseases and by the International Osteoporosis Foundation", 
        "pagination": "1933-1948", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1103878860"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/s00198-018-4534-5"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "29740667"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/s00198-018-4534-5", 
          "https://app.dimensions.ai/details/publication/pub.1103878860"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-11-24T21:03", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20221124/entities/gbq_results/article/article_762.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1007/s00198-018-4534-5"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00198-018-4534-5'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00198-018-4534-5'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00198-018-4534-5'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00198-018-4534-5'


     

    This table displays all metadata directly associated to this object as RDF triples.

    401 TRIPLES      21 PREDICATES      149 URIs      113 LITERALS      16 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/s00198-018-4534-5 schema:about N04957b808107449b96aaeb271cb683b8
    2 N0641336d5e1e40eb9ebc90dfe6a957b6
    3 N16f23f85b1bc4ba6b3bb7b8651975389
    4 N3b78f0388ac7407795487dc080653f30
    5 N44023411777545e5b832e2b1b6ce4b61
    6 N6174510fa130480e9b6eadc2bad65648
    7 Na714ea654ee449cfa87983a4d13e0df3
    8 Nb733d94c2de449a1b87813bccb12ab75
    9 Nc4fa0220aa2046c09071429a9cb3ef68
    10 anzsrc-for:11
    11 anzsrc-for:1103
    12 schema:author N6ab84806d85842fbacb39882ea15a5ea
    13 schema:citation sg:pub.10.1007/bf01623818
    14 sg:pub.10.1007/s00198-003-1448-6
    15 sg:pub.10.1007/s00198-005-1935-z
    16 sg:pub.10.1007/s00198-005-2012-3
    17 sg:pub.10.1007/s00198-006-0228-5
    18 sg:pub.10.1007/s00198-006-0320-x
    19 sg:pub.10.1007/s00198-008-0776-y
    20 sg:pub.10.1007/s00198-010-1179-4
    21 sg:pub.10.1007/s00198-012-1895-z
    22 sg:pub.10.1007/s00198-012-2074-y
    23 sg:pub.10.1007/s00198-014-2888-x
    24 sg:pub.10.1007/s00198-014-3006-9
    25 sg:pub.10.1007/s00198-016-3898-7
    26 sg:pub.10.1007/s001980170095
    27 sg:pub.10.1007/s00223-017-0317-9
    28 sg:pub.10.1007/s00394-009-0014-1
    29 sg:pub.10.1007/s00394-010-0142-7
    30 sg:pub.10.1007/s00394-013-0544-4
    31 sg:pub.10.1007/s00404-009-1345-0
    32 sg:pub.10.1007/s00774-010-0256-2
    33 sg:pub.10.1007/s12603-015-0544-6
    34 sg:pub.10.1038/ejcn.2009.156
    35 sg:pub.10.1038/ejcn.2012.54
    36 sg:pub.10.1038/sj.ejcn.1602659
    37 sg:pub.10.1038/srep09151
    38 sg:pub.10.1038/srep19783
    39 sg:pub.10.1186/1475-2891-10-41
    40 sg:pub.10.1186/1475-2891-8-41
    41 schema:datePublished 2018-05-08
    42 schema:datePublishedReg 2018-05-08
    43 schema:description A summary of systematic reviews and meta-analyses addressing the benefits and risks of dietary protein intakes for bone health in adults suggests that dietary protein levels even above the current RDA may be beneficial in reducing bone loss and hip fracture risk, provided calcium intakes are adequate. Several systematic reviews and meta-analyses have addressed the benefits and risks of dietary protein intakes for bone health in adults. This narrative review of the literature summarizes and synthesizes recent systematic reviews and meta-analyses and highlights key messages. Adequate supplies of dietary protein are required for optimal bone growth and maintenance of healthy bone. Variation in protein intakes within the “normal” range accounts for 2–4% of BMD variance in adults. In older people with osteoporosis, higher protein intake (≥ 0.8-g/kg body weight/day, i.e., above the current RDA) is associated with higher BMD, a slower rate of bone loss, and reduced risk of hip fracture, provided that dietary calcium intakes are adequate. Intervention with dietary protein supplements attenuate age-related BMD decrease and reduce bone turnover marker levels, together with an increase in IGF-I and a decrease in PTH. There is no evidence that diet-derived acid load is deleterious for bone health. Thus, insufficient dietary protein intakes may be a more severe problem than protein excess in the elderly. Long-term, well-controlled randomized trials are required to further assess the influence of dietary protein intakes on fracture risk.
    44 schema:genre article
    45 schema:isAccessibleForFree false
    46 schema:isPartOf N1e35d3ef415f4922bf19eca0048abb0a
    47 N7334f0616061421b9e8f3f26eb5aec1e
    48 sg:journal.1100834
    49 schema:keywords BMD
    50 BMD decrease
    51 BMD variance
    52 Clinical
    53 European Society
    54 IGF
    55 International Osteoporosis Foundation
    56 PTH
    57 RDA
    58 account
    59 acid load
    60 adequate supply
    61 adults
    62 aspects
    63 benefits
    64 bone
    65 bone growth
    66 bone health
    67 bone loss
    68 bone turnover marker levels
    69 calcium intake
    70 consensus paper
    71 current RDA
    72 decrease
    73 dietary calcium intake
    74 dietary protein
    75 dietary protein intake
    76 dietary protein level
    77 dietary protein supplement
    78 disease
    79 economical aspects
    80 evidence
    81 excess
    82 expert consensus paper
    83 foundation
    84 fracture risk
    85 fractures
    86 growth
    87 health
    88 healthy bone
    89 high protein intake
    90 higher BMD
    91 hip fracture
    92 hip fracture risk
    93 increase
    94 influence
    95 insufficient dietary protein intake
    96 intake
    97 intervention
    98 key messages
    99 levels
    100 load
    101 loss
    102 maintenance
    103 marker levels
    104 messages
    105 musculoskeletal diseases
    106 narrative review
    107 older people
    108 optimal bone growth
    109 osteoarthritis
    110 osteoporosis
    111 paper
    112 people
    113 problem
    114 protein
    115 protein excess
    116 protein intake
    117 protein levels
    118 protein supplement
    119 randomized trials
    120 rate
    121 recent systematic review
    122 review
    123 risk
    124 safety
    125 severe problems
    126 slower rate
    127 society
    128 summarizes
    129 summary
    130 supplements
    131 supply
    132 systematic review
    133 trials
    134 variance
    135 variation
    136 schema:name Benefits and safety of dietary protein for bone health—an expert consensus paper endorsed by the European Society for Clinical and Economical Aspects of Osteopororosis, Osteoarthritis, and Musculoskeletal Diseases and by the International Osteoporosis Foundation
    137 schema:pagination 1933-1948
    138 schema:productId N428d50543a6f4f87877136d76b12ac34
    139 N578c4f5868d44753898cc0ae7bfb6548
    140 N66835d20ada74be98504ac77ca27c2e2
    141 schema:sameAs https://app.dimensions.ai/details/publication/pub.1103878860
    142 https://doi.org/10.1007/s00198-018-4534-5
    143 schema:sdDatePublished 2022-11-24T21:03
    144 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    145 schema:sdPublisher N295dee3293e243129161d1c56f4ca248
    146 schema:url https://doi.org/10.1007/s00198-018-4534-5
    147 sgo:license sg:explorer/license/
    148 sgo:sdDataset articles
    149 rdf:type schema:ScholarlyArticle
    150 N04957b808107449b96aaeb271cb683b8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    151 schema:name Calcium, Dietary
    152 rdf:type schema:DefinedTerm
    153 N0641336d5e1e40eb9ebc90dfe6a957b6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    154 schema:name Humans
    155 rdf:type schema:DefinedTerm
    156 N16f23f85b1bc4ba6b3bb7b8651975389 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    157 schema:name Osteoporotic Fractures
    158 rdf:type schema:DefinedTerm
    159 N1e35d3ef415f4922bf19eca0048abb0a schema:volumeNumber 29
    160 rdf:type schema:PublicationVolume
    161 N295dee3293e243129161d1c56f4ca248 schema:name Springer Nature - SN SciGraph project
    162 rdf:type schema:Organization
    163 N3243f4b0f2ff4c37b14b248536bf8407 rdf:first sg:person.0675133170.01
    164 rdf:rest Nb233e926c5f04d0ca6b8e0f51ce4aef2
    165 N361a45a8b66743eba94f7b38af67065f rdf:first sg:person.0654664237.90
    166 rdf:rest Ndf0303c206ed434ba14da2f15d459636
    167 N3aa7a7ca213c4c568d439a0ff8dd416e rdf:first sg:person.01201650421.06
    168 rdf:rest N6b0c0cd786cf4e468c7f538fe5970562
    169 N3b78f0388ac7407795487dc080653f30 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    170 schema:name Risk Assessment
    171 rdf:type schema:DefinedTerm
    172 N428d50543a6f4f87877136d76b12ac34 schema:name dimensions_id
    173 schema:value pub.1103878860
    174 rdf:type schema:PropertyValue
    175 N44023411777545e5b832e2b1b6ce4b61 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    176 schema:name Bone Remodeling
    177 rdf:type schema:DefinedTerm
    178 N578c4f5868d44753898cc0ae7bfb6548 schema:name doi
    179 schema:value 10.1007/s00198-018-4534-5
    180 rdf:type schema:PropertyValue
    181 N6174510fa130480e9b6eadc2bad65648 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    182 schema:name Acid-Base Equilibrium
    183 rdf:type schema:DefinedTerm
    184 N66835d20ada74be98504ac77ca27c2e2 schema:name pubmed_id
    185 schema:value 29740667
    186 rdf:type schema:PropertyValue
    187 N6ab84806d85842fbacb39882ea15a5ea rdf:first sg:person.01117504756.04
    188 rdf:rest Nc24d22fa152d401cb62da5af684293cf
    189 N6b0c0cd786cf4e468c7f538fe5970562 rdf:first sg:person.0633767254.51
    190 rdf:rest Nff20781e300e4f239c2cd4b215e03056
    191 N7334f0616061421b9e8f3f26eb5aec1e schema:issueNumber 9
    192 rdf:type schema:PublicationIssue
    193 N9b6c9a8344d740a68c34261c327d9d8f rdf:first sg:person.0714345342.23
    194 rdf:rest N3243f4b0f2ff4c37b14b248536bf8407
    195 Na714ea654ee449cfa87983a4d13e0df3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    196 schema:name Dietary Proteins
    197 rdf:type schema:DefinedTerm
    198 Nb233e926c5f04d0ca6b8e0f51ce4aef2 rdf:first sg:person.01270403025.38
    199 rdf:rest N3aa7a7ca213c4c568d439a0ff8dd416e
    200 Nb733d94c2de449a1b87813bccb12ab75 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    201 schema:name Osteoporosis
    202 rdf:type schema:DefinedTerm
    203 Nc24d22fa152d401cb62da5af684293cf rdf:first sg:person.01064056326.93
    204 rdf:rest Nd590f82bf637402a8837301db2abd891
    205 Nc4fa0220aa2046c09071429a9cb3ef68 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    206 schema:name Bone Density
    207 rdf:type schema:DefinedTerm
    208 Nd590f82bf637402a8837301db2abd891 rdf:first sg:person.010244741404.52
    209 rdf:rest Nfdc668fdba78463c83870e14ebc30e15
    210 Ndf0303c206ed434ba14da2f15d459636 rdf:first sg:person.0663427426.32
    211 rdf:rest N9b6c9a8344d740a68c34261c327d9d8f
    212 Nfdc668fdba78463c83870e14ebc30e15 rdf:first sg:person.0772574427.82
    213 rdf:rest N361a45a8b66743eba94f7b38af67065f
    214 Nff20781e300e4f239c2cd4b215e03056 rdf:first sg:person.01043351033.16
    215 rdf:rest rdf:nil
    216 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    217 schema:name Medical and Health Sciences
    218 rdf:type schema:DefinedTerm
    219 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
    220 schema:name Clinical Sciences
    221 rdf:type schema:DefinedTerm
    222 sg:journal.1100834 schema:issn 0937-941X
    223 1433-2965
    224 schema:name Osteoporosis International
    225 schema:publisher Springer Nature
    226 rdf:type schema:Periodical
    227 sg:person.010244741404.52 schema:affiliation grid-institutes:grid.150338.c
    228 schema:familyName Bonjour
    229 schema:givenName J.-P.
    230 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010244741404.52
    231 rdf:type schema:Person
    232 sg:person.01043351033.16 schema:affiliation grid-institutes:grid.4861.b
    233 schema:familyName Reginster
    234 schema:givenName J.-Y.
    235 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01043351033.16
    236 rdf:type schema:Person
    237 sg:person.01064056326.93 schema:affiliation grid-institutes:grid.150338.c
    238 schema:familyName Biver
    239 schema:givenName E.
    240 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01064056326.93
    241 rdf:type schema:Person
    242 sg:person.01117504756.04 schema:affiliation grid-institutes:grid.150338.c
    243 schema:familyName Rizzoli
    244 schema:givenName R.
    245 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01117504756.04
    246 rdf:type schema:Person
    247 sg:person.01201650421.06 schema:affiliation grid-institutes:grid.169077.e
    248 schema:familyName Weaver
    249 schema:givenName C.
    250 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01201650421.06
    251 rdf:type schema:Person
    252 sg:person.01270403025.38 schema:affiliation grid-institutes:grid.38142.3c
    253 schema:familyName Sahni
    254 schema:givenName S.
    255 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01270403025.38
    256 rdf:type schema:Person
    257 sg:person.0633767254.51 schema:affiliation grid-institutes:grid.14709.3b
    258 schema:familyName Weiler
    259 schema:givenName H.
    260 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0633767254.51
    261 rdf:type schema:Person
    262 sg:person.0654664237.90 schema:affiliation grid-institutes:grid.63984.30
    263 schema:familyName Goltzman
    264 schema:givenName D.
    265 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0654664237.90
    266 rdf:type schema:Person
    267 sg:person.0663427426.32 schema:affiliation grid-institutes:None
    268 schema:familyName Kanis
    269 schema:givenName J. A.
    270 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0663427426.32
    271 rdf:type schema:Person
    272 sg:person.0675133170.01 schema:affiliation grid-institutes:grid.154185.c
    273 schema:familyName Rejnmark
    274 schema:givenName L.
    275 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0675133170.01
    276 rdf:type schema:Person
    277 sg:person.0714345342.23 schema:affiliation grid-institutes:grid.254748.8
    278 schema:familyName Lappe
    279 schema:givenName J.
    280 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0714345342.23
    281 rdf:type schema:Person
    282 sg:person.0772574427.82 schema:affiliation grid-institutes:grid.494717.8
    283 schema:familyName Coxam
    284 schema:givenName V.
    285 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0772574427.82
    286 rdf:type schema:Person
    287 sg:pub.10.1007/bf01623818 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032889900
    288 https://doi.org/10.1007/bf01623818
    289 rdf:type schema:CreativeWork
    290 sg:pub.10.1007/s00198-003-1448-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024758573
    291 https://doi.org/10.1007/s00198-003-1448-6
    292 rdf:type schema:CreativeWork
    293 sg:pub.10.1007/s00198-005-1935-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1044610711
    294 https://doi.org/10.1007/s00198-005-1935-z
    295 rdf:type schema:CreativeWork
    296 sg:pub.10.1007/s00198-005-2012-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037015139
    297 https://doi.org/10.1007/s00198-005-2012-3
    298 rdf:type schema:CreativeWork
    299 sg:pub.10.1007/s00198-006-0228-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030588485
    300 https://doi.org/10.1007/s00198-006-0228-5
    301 rdf:type schema:CreativeWork
    302 sg:pub.10.1007/s00198-006-0320-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1036644381
    303 https://doi.org/10.1007/s00198-006-0320-x
    304 rdf:type schema:CreativeWork
    305 sg:pub.10.1007/s00198-008-0776-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1035512079
    306 https://doi.org/10.1007/s00198-008-0776-y
    307 rdf:type schema:CreativeWork
    308 sg:pub.10.1007/s00198-010-1179-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047579321
    309 https://doi.org/10.1007/s00198-010-1179-4
    310 rdf:type schema:CreativeWork
    311 sg:pub.10.1007/s00198-012-1895-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1014880500
    312 https://doi.org/10.1007/s00198-012-1895-z
    313 rdf:type schema:CreativeWork
    314 sg:pub.10.1007/s00198-012-2074-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1046005055
    315 https://doi.org/10.1007/s00198-012-2074-y
    316 rdf:type schema:CreativeWork
    317 sg:pub.10.1007/s00198-014-2888-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1006358462
    318 https://doi.org/10.1007/s00198-014-2888-x
    319 rdf:type schema:CreativeWork
    320 sg:pub.10.1007/s00198-014-3006-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045480358
    321 https://doi.org/10.1007/s00198-014-3006-9
    322 rdf:type schema:CreativeWork
    323 sg:pub.10.1007/s00198-016-3898-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006659375
    324 https://doi.org/10.1007/s00198-016-3898-7
    325 rdf:type schema:CreativeWork
    326 sg:pub.10.1007/s001980170095 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040028886
    327 https://doi.org/10.1007/s001980170095
    328 rdf:type schema:CreativeWork
    329 sg:pub.10.1007/s00223-017-0317-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091245119
    330 https://doi.org/10.1007/s00223-017-0317-9
    331 rdf:type schema:CreativeWork
    332 sg:pub.10.1007/s00394-009-0014-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025468953
    333 https://doi.org/10.1007/s00394-009-0014-1
    334 rdf:type schema:CreativeWork
    335 sg:pub.10.1007/s00394-010-0142-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036858365
    336 https://doi.org/10.1007/s00394-010-0142-7
    337 rdf:type schema:CreativeWork
    338 sg:pub.10.1007/s00394-013-0544-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046674445
    339 https://doi.org/10.1007/s00394-013-0544-4
    340 rdf:type schema:CreativeWork
    341 sg:pub.10.1007/s00404-009-1345-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035696652
    342 https://doi.org/10.1007/s00404-009-1345-0
    343 rdf:type schema:CreativeWork
    344 sg:pub.10.1007/s00774-010-0256-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041474477
    345 https://doi.org/10.1007/s00774-010-0256-2
    346 rdf:type schema:CreativeWork
    347 sg:pub.10.1007/s12603-015-0544-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029051322
    348 https://doi.org/10.1007/s12603-015-0544-6
    349 rdf:type schema:CreativeWork
    350 sg:pub.10.1038/ejcn.2009.156 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050754008
    351 https://doi.org/10.1038/ejcn.2009.156
    352 rdf:type schema:CreativeWork
    353 sg:pub.10.1038/ejcn.2012.54 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048029628
    354 https://doi.org/10.1038/ejcn.2012.54
    355 rdf:type schema:CreativeWork
    356 sg:pub.10.1038/sj.ejcn.1602659 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023385536
    357 https://doi.org/10.1038/sj.ejcn.1602659
    358 rdf:type schema:CreativeWork
    359 sg:pub.10.1038/srep09151 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022532391
    360 https://doi.org/10.1038/srep09151
    361 rdf:type schema:CreativeWork
    362 sg:pub.10.1038/srep19783 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030185418
    363 https://doi.org/10.1038/srep19783
    364 rdf:type schema:CreativeWork
    365 sg:pub.10.1186/1475-2891-10-41 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005924870
    366 https://doi.org/10.1186/1475-2891-10-41
    367 rdf:type schema:CreativeWork
    368 sg:pub.10.1186/1475-2891-8-41 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035615315
    369 https://doi.org/10.1186/1475-2891-8-41
    370 rdf:type schema:CreativeWork
    371 grid-institutes:None schema:alternateName Institute for Health and Ageing, Catholic University of Australia, Melbourne, Australia
    372 schema:name Institute for Health and Ageing, Catholic University of Australia, Melbourne, Australia
    373 University of Sheffield, Sheffield, UK
    374 rdf:type schema:Organization
    375 grid-institutes:grid.14709.3b schema:alternateName School of Human Nutrition, McGill University, Montreal, QC, Canada
    376 schema:name School of Human Nutrition, McGill University, Montreal, QC, Canada
    377 rdf:type schema:Organization
    378 grid-institutes:grid.150338.c schema:alternateName Division of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, 1211, Geneva 14, Switzerland
    379 schema:name Division of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, 1211, Geneva 14, Switzerland
    380 rdf:type schema:Organization
    381 grid-institutes:grid.154185.c schema:alternateName Aarhus University Hospital, Aarhus, Denmark
    382 schema:name Aarhus University Hospital, Aarhus, Denmark
    383 rdf:type schema:Organization
    384 grid-institutes:grid.169077.e schema:alternateName Women’s Global Health Institute, Department of Nutrition Science, Purdue University, Purdue, West Lafayette, IN, USA
    385 schema:name Women’s Global Health Institute, Department of Nutrition Science, Purdue University, Purdue, West Lafayette, IN, USA
    386 rdf:type schema:Organization
    387 grid-institutes:grid.254748.8 schema:alternateName College of Nursing, Creighton University, Creighton, NE, USA
    388 schema:name College of Nursing, Creighton University, Creighton, NE, USA
    389 rdf:type schema:Organization
    390 grid-institutes:grid.38142.3c schema:alternateName Hebrew SeniorLife and Harvard Medical School, Institute for Aging Research, Boston, MA, USA
    391 schema:name Hebrew SeniorLife and Harvard Medical School, Institute for Aging Research, Boston, MA, USA
    392 rdf:type schema:Organization
    393 grid-institutes:grid.4861.b schema:alternateName Department of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium
    394 schema:name Department of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium
    395 rdf:type schema:Organization
    396 grid-institutes:grid.494717.8 schema:alternateName INRA, Unité de Nutrition Humaine, CRNH Auvergne, Université Clermont Auvergne, F-63000, Clermont-Ferrand, France
    397 schema:name INRA, Unité de Nutrition Humaine, CRNH Auvergne, Université Clermont Auvergne, F-63000, Clermont-Ferrand, France
    398 rdf:type schema:Organization
    399 grid-institutes:grid.63984.30 schema:alternateName McGill University Health Center, Montreal, Canada
    400 schema:name McGill University Health Center, Montreal, Canada
    401 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...