Estimates of optimal vitamin D status View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2005-03-18

AUTHORS

Bess Dawson-Hughes, Robert P. Heaney, Michael F. Holick, Paul Lips, Pierre J. Meunier, Reinhold Vieth

ABSTRACT

Vitamin D has captured attention as an important determinant of bone health, but there is no common definition of optimal vitamin D status. Herein, we address the question: What is the optimal circulating level of 25-hydroxyvitamin D [25(OH)D] for the skeleton? The opinions of the authors on the minimum level of serum 25(OH)D that is optimal for fracture prevention varied between 50 and 80 nmol/l. However, for five of the six authors, the minimum desirable 25(OH)D concentration clusters between 70 and 80 nmol/l. The authors recognize that the average older man and woman will need intakes of at least 20 to 25 mcg (800 to 1,000 IU) per day of vitamin D3 to reach a serum 25(OH)D level of 75 nmol/l. Based on the available evidence, we believe that if older men and women maintain serum levels of 25(OH)D that are higher than the consensus median threshold of 75 nmol/l, they will be at lower risk of fracture. More... »

PAGES

713-716

Journal

TITLE

Osteoporosis International

ISSUE

7

VOLUME

16

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00198-005-1867-7

DOI

http://dx.doi.org/10.1007/s00198-005-1867-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1027048571

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15776217


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