Long-term outcomes of a randomized controlled trial comparing trans-obturator vaginal mesh with native tissue repair in the treatment of anterior ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-09-10

AUTHORS

Lucie Allègre, Geertje Callewaert, Sandrine Alonso, Arnaud Cornille, Hervé Fernandez, Georges Eglin, Renaud de Tayrac

ABSTRACT

Introduction and hypothesisThe aim of this study was to report the long-term subjective and objective outcomes after transvaginal mesh (TVM) or native tissue repair.MethodsProspective, randomized, multicenter study conducted between April 2005 and December 2009 comparing anterior colporrhaphy with trans-obturator vaginal mesh (Pelvitex/Ugytex®, Sofradim, Trevoux, France) for the treatment of anterior vaginal wall prolapse. The primary endpoint was functional recurrence rate 5–8 years after surgery. Secondary endpoints consisted of anatomical results, mesh-related morbidity and patient satisfaction measured through validated questionnaires.ResultsOf the 147 women originally included, 75 (51%) were successfully re-contacted a median of 7 years after the initial surgery. The primary outcome, subjective recurrence of prolapse, was similar between the TVM and the anterior colporrhaphy groups (31 vs 34% respectively). Anatomical recurrence was less likely in the TVM group (67 vs 24%, p = 0.004). Mesh exposure occurred in 4 of the 39 patients (13%) during follow-up, 2 of which had a surgical reintervention. Reintervention for prolapse took place in 7 patients (9%).ConclusionSeven-year follow-up showed similar functional outcomes for mesh and native tissue repair in anterior vaginal wall prolapse. TVM did not reduce repeat surgery in the long term; it did, however, reduce anatomical recurrence. Mesh exposure rates were relatively high, but no difference in outcome of pain or dyspareunia was noted. More... »

PAGES

745-753

References to SciGraph publications

  • 2007-02-28. Risk factors for the recurrence of pelvic organ prolapse after vaginal surgery: a review at 5 years after surgery in INTERNATIONAL UROGYNECOLOGY JOURNAL
  • 2016-02-02. Long-term outcome after transvaginal mesh repair of pelvic organ prolapse in INTERNATIONAL UROGYNECOLOGY JOURNAL
  • 2013-03-20. Comparison between trans-obturator trans-vaginal mesh and traditional anterior colporrhaphy in the treatment of anterior vaginal wall prolapse: results of a French RCT in INTERNATIONAL UROGYNECOLOGY JOURNAL
  • 2014-01-03. Repair of Pelvic Organ Prolapse: What is the Goal? in CURRENT UROLOGY REPORTS
  • 2003-07-25. A short form of the Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire (PISQ-12) in INTERNATIONAL UROGYNECOLOGY JOURNAL
  • 2010-12-08. An International Urogynecological Association (IUGA) / International Continence Society (ICS) joint terminology and classification of the complications related directly to the insertion of prostheses (meshes, implants, tapes) & grafts in female pelvic floor surgery in INTERNATIONAL UROGYNECOLOGY JOURNAL
  • 2001-06. The Standardization of Terminology for Researchers in Female Pelvic Floor Disorders in INTERNATIONAL UROGYNECOLOGY JOURNAL
  • 2009-12-15. Validation of the Patient Global Impression of Improvement (PGI-I) for urogenital prolapse in INTERNATIONAL UROGYNECOLOGY JOURNAL
  • 2015-01-27. Sexual Health and Well-being Among Older Men and Women in England: Findings from the English Longitudinal Study of Ageing in ARCHIVES OF SEXUAL BEHAVIOR
  • 2010-06-02. Shrinkage of intraperitoneal onlay mesh in sheep: coated polyester mesh versus covered polypropylene mesh in HERNIA
  • 2011-03-22. Incidence and management of graft erosion, wound granulation, and dyspareunia following vaginal prolapse repair with graft materials: a systematic review in INTERNATIONAL UROGYNECOLOGY JOURNAL
  • 2007-09-20. The age distribution, rates, and types of surgery for pelvic organ prolapse in the USA in INTERNATIONAL UROGYNECOLOGY JOURNAL
  • 2017-11-22. Long-term outcome of vaginal mesh or native tissue in recurrent prolapse: a randomized controlled trial in INTERNATIONAL UROGYNECOLOGY JOURNAL
  • 2005-10-15. Transvaginal mesh technique for pelvic organ prolapse repair: mesh exposure management and risk factors in INTERNATIONAL UROGYNECOLOGY JOURNAL
  • 2006-08-29. Collagen-coated vs noncoated low-weight polypropylene meshes in a sheep model for vaginal surgery. A pilot study in INTERNATIONAL UROGYNECOLOGY JOURNAL
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00192-019-04073-x

    DOI

    http://dx.doi.org/10.1007/s00192-019-04073-x

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1120961131

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/31506808


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Clinical Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Female", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "France", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Gynecologic Surgical Procedures", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Pelvic Organ Prolapse", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Prospective Studies", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Surgical Mesh", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Treatment Outcome", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Uterine Prolapse", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Vagina", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Department of Obstetrics and Gynecology, CHU N\u00eemes, University of Montpellier, N\u00eemes, France", 
              "id": "http://www.grid.ac/institutes/grid.411165.6", 
              "name": [
                "Department of Obstetrics and Gynecology, CHU N\u00eemes, University of Montpellier, N\u00eemes, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "All\u00e8gre", 
            "givenName": "Lucie", 
            "id": "sg:person.016446463714.37", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016446463714.37"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Obstetrics and Gynecology, N\u00eemes University Hospital, Place du Pr Debr\u00e9, 30029, N\u00eemes Cedex 9, France", 
              "id": "http://www.grid.ac/institutes/grid.411165.6", 
              "name": [
                "Department of Obstetrics and Gynecology, CHU N\u00eemes, University of Montpellier, N\u00eemes, France", 
                "Department of Obstetrics and Gynecology, University Hospitals Leuven, Leuven, Belgium", 
                "Department of Obstetrics and Gynecology, N\u00eemes University Hospital, Place du Pr Debr\u00e9, 30029, N\u00eemes Cedex 9, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Callewaert", 
            "givenName": "Geertje", 
            "id": "sg:person.01067455441.33", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01067455441.33"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Biostatistics, Epidemiology, Public Health and Innovation in Methodology (BESPIM), CHU N\u00eemes, University of Montpellier, N\u00eemes, France", 
              "id": "http://www.grid.ac/institutes/grid.411165.6", 
              "name": [
                "Department of Biostatistics, Epidemiology, Public Health and Innovation in Methodology (BESPIM), CHU N\u00eemes, University of Montpellier, N\u00eemes, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Alonso", 
            "givenName": "Sandrine", 
            "id": "sg:person.01041530067.22", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01041530067.22"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Obstetrics and Gynecology, Clinique Beau Soleil, Montpellier, France", 
              "id": "http://www.grid.ac/institutes/grid.492653.f", 
              "name": [
                "Department of Obstetrics and Gynecology, Clinique Beau Soleil, Montpellier, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Cornille", 
            "givenName": "Arnaud", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Obstetrics and Gynecology, Kremin Bic\u00eatre Hospital, Kremin Bic\u00eatre, France", 
              "id": "http://www.grid.ac/institutes/grid.413784.d", 
              "name": [
                "Department of Obstetrics and Gynecology, Kremin Bic\u00eatre Hospital, Kremin Bic\u00eatre, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Fernandez", 
            "givenName": "Herv\u00e9", 
            "id": "sg:person.01114030527.71", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01114030527.71"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Obstetrics and Gynecology, Clinique Champeau, B\u00e9ziers, France", 
              "id": "http://www.grid.ac/institutes/None", 
              "name": [
                "Department of Obstetrics and Gynecology, Clinique Champeau, B\u00e9ziers, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Eglin", 
            "givenName": "Georges", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Obstetrics and Gynecology, CHU N\u00eemes, University of Montpellier, N\u00eemes, France", 
              "id": "http://www.grid.ac/institutes/grid.411165.6", 
              "name": [
                "Department of Obstetrics and Gynecology, CHU N\u00eemes, University of Montpellier, N\u00eemes, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "de Tayrac", 
            "givenName": "Renaud", 
            "id": "sg:person.046406024.48", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.046406024.48"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1007/s00192-013-2075-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048596364", 
              "https://doi.org/10.1007/s00192-013-2075-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10029-010-0682-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044337965", 
              "https://doi.org/10.1007/s10029-010-0682-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00192-009-1069-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041596540", 
              "https://doi.org/10.1007/s00192-009-1069-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/pl00004033", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050470638", 
              "https://doi.org/10.1007/pl00004033"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00192-011-1384-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035346141", 
              "https://doi.org/10.1007/s00192-011-1384-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00192-007-0321-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038050972", 
              "https://doi.org/10.1007/s00192-007-0321-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00192-017-3512-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1092893258", 
              "https://doi.org/10.1007/s00192-017-3512-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10508-014-0465-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037209306", 
              "https://doi.org/10.1007/s10508-014-0465-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00192-007-0457-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006847853", 
              "https://doi.org/10.1007/s00192-007-0457-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11934-013-0385-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043669409", 
              "https://doi.org/10.1007/s11934-013-0385-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00192-010-1324-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050436373", 
              "https://doi.org/10.1007/s00192-010-1324-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00192-005-0003-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022812567", 
              "https://doi.org/10.1007/s00192-005-0003-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00192-006-0176-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021497124", 
              "https://doi.org/10.1007/s00192-006-0176-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00192-003-1063-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036729577", 
              "https://doi.org/10.1007/s00192-003-1063-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00192-015-2939-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033217054", 
              "https://doi.org/10.1007/s00192-015-2939-7"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2019-09-10", 
        "datePublishedReg": "2019-09-10", 
        "description": "Introduction and hypothesisThe aim of this study was to report the long-term subjective and objective outcomes after transvaginal mesh (TVM) or native tissue repair.MethodsProspective, randomized, multicenter study conducted between April 2005 and December 2009 comparing anterior colporrhaphy with trans-obturator vaginal mesh (Pelvitex/Ugytex\u00ae, Sofradim, Trevoux, France) for the treatment of anterior vaginal wall prolapse. The primary endpoint was functional recurrence rate 5\u20138\u00a0years after surgery. Secondary endpoints consisted of anatomical results, mesh-related morbidity and patient satisfaction measured through validated questionnaires.ResultsOf the 147 women originally included, 75 (51%) were successfully re-contacted a median of 7\u00a0years after the initial surgery. The primary outcome, subjective recurrence of prolapse, was similar between the TVM and the anterior colporrhaphy groups (31 vs 34% respectively). Anatomical recurrence was less likely in the TVM group (67 vs 24%, p\u2009=\u20090.004). Mesh exposure occurred in 4 of the 39 patients (13%) during follow-up, 2 of which had a surgical reintervention. Reintervention for prolapse took place in 7 patients (9%).ConclusionSeven-year follow-up showed similar functional outcomes for mesh and native tissue repair in anterior vaginal wall prolapse. TVM did not reduce repeat surgery in the long term; it did, however, reduce anatomical recurrence. Mesh exposure rates were relatively high, but no difference in outcome of pain or dyspareunia was noted.", 
        "genre": "article", 
        "id": "sg:pub.10.1007/s00192-019-04073-x", 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1045594", 
            "issn": [
              "0937-3462", 
              "1433-3023"
            ], 
            "name": "International Urogynecology Journal", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "4", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "31"
          }
        ], 
        "keywords": [
          "anterior vaginal wall prolapse", 
          "vaginal wall prolapse", 
          "native tissue repair", 
          "transvaginal mesh", 
          "anatomical recurrence", 
          "vaginal mesh", 
          "tissue repair", 
          "mesh-related morbidity", 
          "anterior colporrhaphy group", 
          "outcomes of pain", 
          "mesh exposure rate", 
          "long-term outcomes", 
          "similar functional outcomes", 
          "colporrhaphy group", 
          "surgical reintervention", 
          "primary endpoint", 
          "secondary endpoints", 
          "initial surgery", 
          "mesh exposure", 
          "repeat surgery", 
          "primary outcome", 
          "anterior colporrhaphy", 
          "multicenter study", 
          "hypothesisThe aim", 
          "subjective recurrence", 
          "functional outcome", 
          "patient satisfaction", 
          "anatomical results", 
          "TVM group", 
          "prolapse", 
          "objective outcomes", 
          "surgery", 
          "recurrence", 
          "reintervention", 
          "outcomes", 
          "patients", 
          "exposure rate", 
          "endpoint", 
          "repair", 
          "treatment", 
          "long term", 
          "MethodsProspective", 
          "dyspareunia", 
          "colporrhaphy", 
          "morbidity", 
          "pain", 
          "ResultsOf", 
          "group", 
          "years", 
          "trials", 
          "women", 
          "median", 
          "study", 
          "exposure", 
          "questionnaire", 
          "aim", 
          "rate 5", 
          "differences", 
          "satisfaction", 
          "rate", 
          "results", 
          "introduction", 
          "mesh", 
          "place", 
          "terms"
        ], 
        "name": "Long-term outcomes of a randomized controlled trial comparing trans-obturator vaginal mesh with native tissue repair in the treatment of anterior vaginal wall prolapse", 
        "pagination": "745-753", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1120961131"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/s00192-019-04073-x"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "31506808"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/s00192-019-04073-x", 
          "https://app.dimensions.ai/details/publication/pub.1120961131"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-08-04T17:07", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20220804/entities/gbq_results/article/article_819.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1007/s00192-019-04073-x"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00192-019-04073-x'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00192-019-04073-x'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00192-019-04073-x'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00192-019-04073-x'


     

    This table displays all metadata directly associated to this object as RDF triples.

    280 TRIPLES      21 PREDICATES      115 URIs      92 LITERALS      17 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/s00192-019-04073-x schema:about N1fc489258a4f4a3681b614d19c64ffe5
    2 N2a24ad804b1d46979d3889c8b94f1c0b
    3 N448f5345842240c78ad7ec561f26b459
    4 N586e7f97c82c48759f697541a82bb42d
    5 N797a4a73ba5a4cad91ef48d1370d2570
    6 N7b29f3841d3a46fb885a8bb828988878
    7 N9b43ef078968423da16c19ef7d3397ad
    8 N9ee3c965c0634abbbcdd5085670953e7
    9 Ncc22b82ca1864b779b1fb50ed41deb92
    10 Nfe80dd08e769461982601ca20ae4de51
    11 anzsrc-for:11
    12 anzsrc-for:1103
    13 schema:author Nbcd3cb75290743d7b7c24d1a6021caf2
    14 schema:citation sg:pub.10.1007/pl00004033
    15 sg:pub.10.1007/s00192-003-1063-2
    16 sg:pub.10.1007/s00192-005-0003-8
    17 sg:pub.10.1007/s00192-006-0176-9
    18 sg:pub.10.1007/s00192-007-0321-0
    19 sg:pub.10.1007/s00192-007-0457-y
    20 sg:pub.10.1007/s00192-009-1069-5
    21 sg:pub.10.1007/s00192-010-1324-9
    22 sg:pub.10.1007/s00192-011-1384-5
    23 sg:pub.10.1007/s00192-013-2075-1
    24 sg:pub.10.1007/s00192-015-2939-7
    25 sg:pub.10.1007/s00192-017-3512-3
    26 sg:pub.10.1007/s10029-010-0682-z
    27 sg:pub.10.1007/s10508-014-0465-1
    28 sg:pub.10.1007/s11934-013-0385-y
    29 schema:datePublished 2019-09-10
    30 schema:datePublishedReg 2019-09-10
    31 schema:description Introduction and hypothesisThe aim of this study was to report the long-term subjective and objective outcomes after transvaginal mesh (TVM) or native tissue repair.MethodsProspective, randomized, multicenter study conducted between April 2005 and December 2009 comparing anterior colporrhaphy with trans-obturator vaginal mesh (Pelvitex/Ugytex®, Sofradim, Trevoux, France) for the treatment of anterior vaginal wall prolapse. The primary endpoint was functional recurrence rate 5–8 years after surgery. Secondary endpoints consisted of anatomical results, mesh-related morbidity and patient satisfaction measured through validated questionnaires.ResultsOf the 147 women originally included, 75 (51%) were successfully re-contacted a median of 7 years after the initial surgery. The primary outcome, subjective recurrence of prolapse, was similar between the TVM and the anterior colporrhaphy groups (31 vs 34% respectively). Anatomical recurrence was less likely in the TVM group (67 vs 24%, p = 0.004). Mesh exposure occurred in 4 of the 39 patients (13%) during follow-up, 2 of which had a surgical reintervention. Reintervention for prolapse took place in 7 patients (9%).ConclusionSeven-year follow-up showed similar functional outcomes for mesh and native tissue repair in anterior vaginal wall prolapse. TVM did not reduce repeat surgery in the long term; it did, however, reduce anatomical recurrence. Mesh exposure rates were relatively high, but no difference in outcome of pain or dyspareunia was noted.
    32 schema:genre article
    33 schema:isAccessibleForFree false
    34 schema:isPartOf N19ac31860b1b4c5e9292300992494873
    35 Nc3d25ee413bf4468ac97f2dfbf20a06a
    36 sg:journal.1045594
    37 schema:keywords MethodsProspective
    38 ResultsOf
    39 TVM group
    40 aim
    41 anatomical recurrence
    42 anatomical results
    43 anterior colporrhaphy
    44 anterior colporrhaphy group
    45 anterior vaginal wall prolapse
    46 colporrhaphy
    47 colporrhaphy group
    48 differences
    49 dyspareunia
    50 endpoint
    51 exposure
    52 exposure rate
    53 functional outcome
    54 group
    55 hypothesisThe aim
    56 initial surgery
    57 introduction
    58 long term
    59 long-term outcomes
    60 median
    61 mesh
    62 mesh exposure
    63 mesh exposure rate
    64 mesh-related morbidity
    65 morbidity
    66 multicenter study
    67 native tissue repair
    68 objective outcomes
    69 outcomes
    70 outcomes of pain
    71 pain
    72 patient satisfaction
    73 patients
    74 place
    75 primary endpoint
    76 primary outcome
    77 prolapse
    78 questionnaire
    79 rate
    80 rate 5
    81 recurrence
    82 reintervention
    83 repair
    84 repeat surgery
    85 results
    86 satisfaction
    87 secondary endpoints
    88 similar functional outcomes
    89 study
    90 subjective recurrence
    91 surgery
    92 surgical reintervention
    93 terms
    94 tissue repair
    95 transvaginal mesh
    96 treatment
    97 trials
    98 vaginal mesh
    99 vaginal wall prolapse
    100 women
    101 years
    102 schema:name Long-term outcomes of a randomized controlled trial comparing trans-obturator vaginal mesh with native tissue repair in the treatment of anterior vaginal wall prolapse
    103 schema:pagination 745-753
    104 schema:productId N0d570df0dca2401fabaa34c7a48222a6
    105 N82d40d8607a14b5c87a68076907b573d
    106 N8bfba0a8801a4674a574f2c28e2e8fd9
    107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1120961131
    108 https://doi.org/10.1007/s00192-019-04073-x
    109 schema:sdDatePublished 2022-08-04T17:07
    110 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    111 schema:sdPublisher N6dabac51a4744f738d7ced02616b9051
    112 schema:url https://doi.org/10.1007/s00192-019-04073-x
    113 sgo:license sg:explorer/license/
    114 sgo:sdDataset articles
    115 rdf:type schema:ScholarlyArticle
    116 N0d570df0dca2401fabaa34c7a48222a6 schema:name doi
    117 schema:value 10.1007/s00192-019-04073-x
    118 rdf:type schema:PropertyValue
    119 N19ac31860b1b4c5e9292300992494873 schema:issueNumber 4
    120 rdf:type schema:PublicationIssue
    121 N1fc489258a4f4a3681b614d19c64ffe5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    122 schema:name Female
    123 rdf:type schema:DefinedTerm
    124 N2a24ad804b1d46979d3889c8b94f1c0b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    125 schema:name Gynecologic Surgical Procedures
    126 rdf:type schema:DefinedTerm
    127 N334b74b5491d40ef8c5dd95f8a90c671 schema:affiliation grid-institutes:grid.492653.f
    128 schema:familyName Cornille
    129 schema:givenName Arnaud
    130 rdf:type schema:Person
    131 N448f5345842240c78ad7ec561f26b459 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    132 schema:name Humans
    133 rdf:type schema:DefinedTerm
    134 N55e1864b373443ae9b400f4f99e26ae4 rdf:first sg:person.01041530067.22
    135 rdf:rest Nb4416c9b84cf40d1b0656724a6fa1cd8
    136 N56d4dc58277b49fbb2ad026bc687819b schema:affiliation grid-institutes:None
    137 schema:familyName Eglin
    138 schema:givenName Georges
    139 rdf:type schema:Person
    140 N586e7f97c82c48759f697541a82bb42d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    141 schema:name Pelvic Organ Prolapse
    142 rdf:type schema:DefinedTerm
    143 N6dabac51a4744f738d7ced02616b9051 schema:name Springer Nature - SN SciGraph project
    144 rdf:type schema:Organization
    145 N797a4a73ba5a4cad91ef48d1370d2570 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    146 schema:name Vagina
    147 rdf:type schema:DefinedTerm
    148 N7b29f3841d3a46fb885a8bb828988878 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    149 schema:name Prospective Studies
    150 rdf:type schema:DefinedTerm
    151 N82d40d8607a14b5c87a68076907b573d schema:name dimensions_id
    152 schema:value pub.1120961131
    153 rdf:type schema:PropertyValue
    154 N8476cd7da1274bcabcb0a7ed92bc3b21 rdf:first sg:person.046406024.48
    155 rdf:rest rdf:nil
    156 N8bfba0a8801a4674a574f2c28e2e8fd9 schema:name pubmed_id
    157 schema:value 31506808
    158 rdf:type schema:PropertyValue
    159 N9b43ef078968423da16c19ef7d3397ad schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    160 schema:name France
    161 rdf:type schema:DefinedTerm
    162 N9ee3c965c0634abbbcdd5085670953e7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    163 schema:name Uterine Prolapse
    164 rdf:type schema:DefinedTerm
    165 Na16ee8ae751d4f14a12ffaedcde9b312 rdf:first sg:person.01067455441.33
    166 rdf:rest N55e1864b373443ae9b400f4f99e26ae4
    167 Na8d47e4151a74e98b87055c09e8bdcc1 rdf:first N56d4dc58277b49fbb2ad026bc687819b
    168 rdf:rest N8476cd7da1274bcabcb0a7ed92bc3b21
    169 Nb4416c9b84cf40d1b0656724a6fa1cd8 rdf:first N334b74b5491d40ef8c5dd95f8a90c671
    170 rdf:rest Nb55467509d2648948e58119c8826091f
    171 Nb55467509d2648948e58119c8826091f rdf:first sg:person.01114030527.71
    172 rdf:rest Na8d47e4151a74e98b87055c09e8bdcc1
    173 Nbcd3cb75290743d7b7c24d1a6021caf2 rdf:first sg:person.016446463714.37
    174 rdf:rest Na16ee8ae751d4f14a12ffaedcde9b312
    175 Nc3d25ee413bf4468ac97f2dfbf20a06a schema:volumeNumber 31
    176 rdf:type schema:PublicationVolume
    177 Ncc22b82ca1864b779b1fb50ed41deb92 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    178 schema:name Treatment Outcome
    179 rdf:type schema:DefinedTerm
    180 Nfe80dd08e769461982601ca20ae4de51 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    181 schema:name Surgical Mesh
    182 rdf:type schema:DefinedTerm
    183 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    184 schema:name Medical and Health Sciences
    185 rdf:type schema:DefinedTerm
    186 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
    187 schema:name Clinical Sciences
    188 rdf:type schema:DefinedTerm
    189 sg:journal.1045594 schema:issn 0937-3462
    190 1433-3023
    191 schema:name International Urogynecology Journal
    192 schema:publisher Springer Nature
    193 rdf:type schema:Periodical
    194 sg:person.01041530067.22 schema:affiliation grid-institutes:grid.411165.6
    195 schema:familyName Alonso
    196 schema:givenName Sandrine
    197 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01041530067.22
    198 rdf:type schema:Person
    199 sg:person.01067455441.33 schema:affiliation grid-institutes:grid.411165.6
    200 schema:familyName Callewaert
    201 schema:givenName Geertje
    202 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01067455441.33
    203 rdf:type schema:Person
    204 sg:person.01114030527.71 schema:affiliation grid-institutes:grid.413784.d
    205 schema:familyName Fernandez
    206 schema:givenName Hervé
    207 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01114030527.71
    208 rdf:type schema:Person
    209 sg:person.016446463714.37 schema:affiliation grid-institutes:grid.411165.6
    210 schema:familyName Allègre
    211 schema:givenName Lucie
    212 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016446463714.37
    213 rdf:type schema:Person
    214 sg:person.046406024.48 schema:affiliation grid-institutes:grid.411165.6
    215 schema:familyName de Tayrac
    216 schema:givenName Renaud
    217 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.046406024.48
    218 rdf:type schema:Person
    219 sg:pub.10.1007/pl00004033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050470638
    220 https://doi.org/10.1007/pl00004033
    221 rdf:type schema:CreativeWork
    222 sg:pub.10.1007/s00192-003-1063-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036729577
    223 https://doi.org/10.1007/s00192-003-1063-2
    224 rdf:type schema:CreativeWork
    225 sg:pub.10.1007/s00192-005-0003-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022812567
    226 https://doi.org/10.1007/s00192-005-0003-8
    227 rdf:type schema:CreativeWork
    228 sg:pub.10.1007/s00192-006-0176-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021497124
    229 https://doi.org/10.1007/s00192-006-0176-9
    230 rdf:type schema:CreativeWork
    231 sg:pub.10.1007/s00192-007-0321-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038050972
    232 https://doi.org/10.1007/s00192-007-0321-0
    233 rdf:type schema:CreativeWork
    234 sg:pub.10.1007/s00192-007-0457-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1006847853
    235 https://doi.org/10.1007/s00192-007-0457-y
    236 rdf:type schema:CreativeWork
    237 sg:pub.10.1007/s00192-009-1069-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041596540
    238 https://doi.org/10.1007/s00192-009-1069-5
    239 rdf:type schema:CreativeWork
    240 sg:pub.10.1007/s00192-010-1324-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050436373
    241 https://doi.org/10.1007/s00192-010-1324-9
    242 rdf:type schema:CreativeWork
    243 sg:pub.10.1007/s00192-011-1384-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035346141
    244 https://doi.org/10.1007/s00192-011-1384-5
    245 rdf:type schema:CreativeWork
    246 sg:pub.10.1007/s00192-013-2075-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048596364
    247 https://doi.org/10.1007/s00192-013-2075-1
    248 rdf:type schema:CreativeWork
    249 sg:pub.10.1007/s00192-015-2939-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033217054
    250 https://doi.org/10.1007/s00192-015-2939-7
    251 rdf:type schema:CreativeWork
    252 sg:pub.10.1007/s00192-017-3512-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092893258
    253 https://doi.org/10.1007/s00192-017-3512-3
    254 rdf:type schema:CreativeWork
    255 sg:pub.10.1007/s10029-010-0682-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1044337965
    256 https://doi.org/10.1007/s10029-010-0682-z
    257 rdf:type schema:CreativeWork
    258 sg:pub.10.1007/s10508-014-0465-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037209306
    259 https://doi.org/10.1007/s10508-014-0465-1
    260 rdf:type schema:CreativeWork
    261 sg:pub.10.1007/s11934-013-0385-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1043669409
    262 https://doi.org/10.1007/s11934-013-0385-y
    263 rdf:type schema:CreativeWork
    264 grid-institutes:None schema:alternateName Department of Obstetrics and Gynecology, Clinique Champeau, Béziers, France
    265 schema:name Department of Obstetrics and Gynecology, Clinique Champeau, Béziers, France
    266 rdf:type schema:Organization
    267 grid-institutes:grid.411165.6 schema:alternateName Department of Biostatistics, Epidemiology, Public Health and Innovation in Methodology (BESPIM), CHU Nîmes, University of Montpellier, Nîmes, France
    268 Department of Obstetrics and Gynecology, CHU Nîmes, University of Montpellier, Nîmes, France
    269 Department of Obstetrics and Gynecology, Nîmes University Hospital, Place du Pr Debré, 30029, Nîmes Cedex 9, France
    270 schema:name Department of Biostatistics, Epidemiology, Public Health and Innovation in Methodology (BESPIM), CHU Nîmes, University of Montpellier, Nîmes, France
    271 Department of Obstetrics and Gynecology, CHU Nîmes, University of Montpellier, Nîmes, France
    272 Department of Obstetrics and Gynecology, Nîmes University Hospital, Place du Pr Debré, 30029, Nîmes Cedex 9, France
    273 Department of Obstetrics and Gynecology, University Hospitals Leuven, Leuven, Belgium
    274 rdf:type schema:Organization
    275 grid-institutes:grid.413784.d schema:alternateName Department of Obstetrics and Gynecology, Kremin Bicêtre Hospital, Kremin Bicêtre, France
    276 schema:name Department of Obstetrics and Gynecology, Kremin Bicêtre Hospital, Kremin Bicêtre, France
    277 rdf:type schema:Organization
    278 grid-institutes:grid.492653.f schema:alternateName Department of Obstetrics and Gynecology, Clinique Beau Soleil, Montpellier, France
    279 schema:name Department of Obstetrics and Gynecology, Clinique Beau Soleil, Montpellier, France
    280 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...