Retropubic vs. transobturator tension-free vaginal tape for female stress urinary incontinence: 3-month results of a randomized controlled trial View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-05-13

AUTHORS

Thomas Aigmüller, Ayman Tammaa, Karl Tamussino, Engelbert Hanzal, Wolfgang Umek, Dieter Kölle, Stephan Kropshofer, Vesna Bjelic-Radisic, Josef Haas, Albrecht Giuliani, Peter F. J. Lang, Oliver Preyer, Ursula Peschers, Katharina Jundt, George Ralph, Andrea Dungl, Paul A. Riss, for the Austrian TVT vs. TVT-O Study Group

ABSTRACT

BackgroundWe conducted a prospective randomized controlled noninferiority trial to compare objective and subjective outcomes of retropubic tension-free vaginal tape (TVT) with those of transobturator tape (TVT-O) as primary treatment for stress urinary incontinence (SUI) in women.Study designThe study was conducted at 25 gynecology units in Austria and Germany; regional and academic hospitals participated. A total of 569 patients were randomly assigned to undergo TVT or TVT-O.ResultsA total of 480 patients (85 %) were examined at 3 months. A negative cough stress test with stable cystometry to 300 ml was seen in 87 % of patients after TVT and in 84 % after TVT-O; 64 % and 59 % of patients, respectively, reported no pad use, and 88 % of patients in both groups considered themselves much or very much better on the Patient Global Impression of Improvement (PGI-I) scale. Quality of life (QoL) as assessed with the SF-12 Health Survey, Kings’ Health Questionnaire, (KHQ), and EuroQol-5D (EQ-5D) was significantly improved in both arms, with no differences between arms. There were no significant differences in postoperative pain or complications.ConclusionsResults of this trial demonstrate noninferiority between TVT and TVT-O with regard to postoperative continence and QoL and suggest little difference in perioperative problems (ClinicalTrials.gov NCT 00441454). More... »

PAGES

1023-1030

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00192-014-2384-z

DOI

http://dx.doi.org/10.1007/s00192-014-2384-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1019936872

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24819327


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24 schema:description BackgroundWe conducted a prospective randomized controlled noninferiority trial to compare objective and subjective outcomes of retropubic tension-free vaginal tape (TVT) with those of transobturator tape (TVT-O) as primary treatment for stress urinary incontinence (SUI) in women.Study designThe study was conducted at 25 gynecology units in Austria and Germany; regional and academic hospitals participated. A total of 569 patients were randomly assigned to undergo TVT or TVT-O.ResultsA total of 480 patients (85 %) were examined at 3 months. A negative cough stress test with stable cystometry to 300 ml was seen in 87 % of patients after TVT and in 84 % after TVT-O; 64 % and 59 % of patients, respectively, reported no pad use, and 88 % of patients in both groups considered themselves much or very much better on the Patient Global Impression of Improvement (PGI-I) scale. Quality of life (QoL) as assessed with the SF-12 Health Survey, Kings’ Health Questionnaire, (KHQ), and EuroQol-5D (EQ-5D) was significantly improved in both arms, with no differences between arms. There were no significant differences in postoperative pain or complications.ConclusionsResults of this trial demonstrate noninferiority between TVT and TVT-O with regard to postoperative continence and QoL and suggest little difference in perioperative problems (ClinicalTrials.gov NCT 00441454).
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