Intrawound vancomycin powder increases post-operative wound complications and does not decrease periprosthetic joint infection in primary total and unicompartmental knee ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-04-09

AUTHORS

Mitsuru Hanada, Shoichi Nishikino, Kensuke Hotta, Hiroki Furuhashi, Hironobu Hoshino, Yukihiro Matsuyama

ABSTRACT

PURPOSE: A frequent reason for revision surgery after total knee arthroplasty (TKA) and unicompartmental knee arthroplasty (UKA) is periprosthetic joint infection (PJI). The efficacy of intrawound VP in preventing PJI after primary TKA or UKA is rarely reported. The purpose of this study was to investigate the efficacy and side effects of local high-dose VP application to the joint to prevent PJI in TKA and UKA. METHODS: From 2010 to 2017, 166 consecutive patients that underwent primary TKA or UKA were enrolled. Seventy-five patients (92 knees) did not receive VP (control group), while 90 patients (110 knees, VP group) received VP (intrawound, 1 g) before capsule closure during TKA and UKA. Aseptic wound complications, such as skin erosion, wound dehiscence, and prolonged wound healing, were evaluated within 3 months post-operatively. PJI was assessed within a year post-operatively. RESULTS: Seven patients (7.6%) in the control group and five patients (4.5%) in the VP group had PJI. No significant differences existed in the PJI rates between the groups. Aseptic operative wound complications occurred in 4 patients (4.3%) and 13 patients (11.8%), whereas prolonged operative wound healing occurred in 3 patients (3.3%) and 14 patients (12.7%) of patients in the control and VP group, respectively. Operative wound complications were significantly frequent in the VP group. CONCLUSIONS: Intrawound VP administration does not decrease PJI occurrence in primary TKA and significantly causes aseptic wound complications. The use of intrawound VP for the prevention of PJI after primary TKA and UKA is not recommended. LEVEL OF EVIDENCE: Level II. More... »

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00167-019-05498-z

DOI

http://dx.doi.org/10.1007/s00167-019-05498-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1113328002

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30968239


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Hamamatsu University", 
          "id": "https://www.grid.ac/institutes/grid.411951.9", 
          "name": [
            "Department of Orthopaedic Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu, 431-3192, Japan. mitsuruhanada@gmail.com."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hanada", 
        "givenName": "Mitsuru", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hamamatsu University", 
          "id": "https://www.grid.ac/institutes/grid.411951.9", 
          "name": [
            "Department of Orthopaedic Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu, 431-3192, Japan."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nishikino", 
        "givenName": "Shoichi", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hamamatsu University", 
          "id": "https://www.grid.ac/institutes/grid.411951.9", 
          "name": [
            "Department of Orthopaedic Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu, 431-3192, Japan."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hotta", 
        "givenName": "Kensuke", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hamamatsu University", 
          "id": "https://www.grid.ac/institutes/grid.411951.9", 
          "name": [
            "Department of Orthopaedic Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu, 431-3192, Japan."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Furuhashi", 
        "givenName": "Hiroki", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hamamatsu University", 
          "id": "https://www.grid.ac/institutes/grid.411951.9", 
          "name": [
            "Department of Orthopaedic Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu, 431-3192, Japan."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hoshino", 
        "givenName": "Hironobu", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hamamatsu University", 
          "id": "https://www.grid.ac/institutes/grid.411951.9", 
          "name": [
            "Department of Orthopaedic Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu, 431-3192, Japan."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Matsuyama", 
        "givenName": "Yukihiro", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s00167-015-3558-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001983643", 
          "https://doi.org/10.1007/s00167-015-3558-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00167-015-3558-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001983643", 
          "https://doi.org/10.1007/s00167-015-3558-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11999-012-2351-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002256629", 
          "https://doi.org/10.1007/s11999-012-2351-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1007/s11999-012-2351-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002256629"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/brs.0b013e318285b219", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003256400"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/brs.0b013e318285b219", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003256400"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.spinee.2015.01.030", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009312538"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/brs.0b013e3181ff2cb1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010006142"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/brs.0b013e3181ff2cb1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010006142"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2474-11-258", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016697813", 
          "https://doi.org/10.1186/1471-2474-11-258"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.arth.2011.03.034", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018772956"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.arth.2011.03.034", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018772956"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/17453679108994458", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022053415"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/17453674.2013.831320", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028881435"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.arth.2015.10.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030061600"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.spinee.2011.04.025", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035678956"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/brs.0000000000000015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036183899"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/brs.0000000000000015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036183899"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/17453670710015229", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037093975"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.arth.2007.02.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040440384"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.wneu.2014.12.033", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044737262"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.arthro.2011.08.301", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045215484"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jcma.2012.02.016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045316618"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jcma.2012.02.016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045316618"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2125.2007.02897.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048264439"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2125.2007.02897.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048264439"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.arth.2014.02.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053448582"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.arth.2014.02.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053448582"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003086-197711000-00033", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060158111"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1302/0301-620x.95b11.33135", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064887199"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/00004623-200205000-00009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068895016"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.15.00988", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068898223"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.15.00988", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068898223"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.15.00988", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068898223"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.15.00988", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068898223"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.g.01570", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068900801"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.g.01570", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068900801"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.g.01570", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068900801"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.j.00772", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068902106"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.j.00772", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068902106"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2106/jbjs.j.00772", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068902106"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3171/2015.7.focus15258", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071081837"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3171/2015.7.focus15258", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071081837"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3171/2015.7.focus15258", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071081837"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3171/2015.7.focus15258", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071081837"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3171/2015.7.focus15258", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071081837"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3171/2015.7.focus15258", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071081837"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1302/0301-620x.71b5.2584249", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079066938"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1302/0301-620x.71b5.2584250", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079066950"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.22038/abjs.2015.3938", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079108632"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079376835", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083243814", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083737573", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/os.12356", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1093044222"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.5371/hp.2018.30.1.37", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1101533265"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00167-019-05353-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1111502297", 
          "https://doi.org/10.1007/s00167-019-05353-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00167-018-5323-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1111577103", 
          "https://doi.org/10.1007/s00167-018-5323-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00167-018-5323-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1111577103", 
          "https://doi.org/10.1007/s00167-018-5323-6"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-04-09", 
    "datePublishedReg": "2019-04-09", 
    "description": "PURPOSE: A frequent reason for revision surgery after total knee arthroplasty (TKA) and unicompartmental knee arthroplasty (UKA) is periprosthetic joint infection (PJI). The efficacy of intrawound VP in preventing PJI after primary TKA or UKA is rarely reported. The purpose of this study was to investigate the efficacy and side effects of local high-dose VP application to the joint to prevent PJI in TKA and UKA.\nMETHODS: From 2010 to 2017, 166 consecutive patients that underwent primary TKA or UKA were enrolled. Seventy-five patients (92 knees) did not receive VP (control group), while 90 patients (110 knees, VP group) received VP (intrawound, 1\u00a0g) before capsule closure during TKA and UKA. Aseptic wound complications, such as skin erosion, wound dehiscence, and prolonged wound healing, were evaluated within 3\u00a0months post-operatively. PJI was assessed within a year post-operatively.\nRESULTS: Seven patients (7.6%) in the control group and five patients (4.5%) in the VP group had PJI. No significant differences existed in the PJI rates between the groups. Aseptic operative wound complications occurred in 4 patients (4.3%) and 13 patients (11.8%), whereas prolonged operative wound healing occurred in 3 patients (3.3%) and 14 patients (12.7%) of patients in the control and VP group, respectively. Operative wound complications were significantly frequent in the VP group.\nCONCLUSIONS: Intrawound VP administration does not decrease PJI occurrence in primary TKA and significantly causes aseptic wound complications. The use of intrawound VP for the prevention of PJI after primary TKA and UKA is not recommended.\nLEVEL OF EVIDENCE: Level II.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00167-019-05498-z", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1104512", 
        "issn": [
          "0942-2056", 
          "1433-7347"
        ], 
        "name": "Knee Surgery, Sports Traumatology, Arthroscopy", 
        "type": "Periodical"
      }
    ], 
    "name": "Intrawound vancomycin powder increases post-operative wound complications and does not decrease periprosthetic joint infection in primary total and unicompartmental knee arthroplasties.", 
    "productId": [
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00167-019-05498-z"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1113328002"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9314730"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30968239"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00167-019-05498-z", 
      "https://app.dimensions.ai/details/publication/pub.1113328002"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-15T09:01", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000375_0000000375/records_91444_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/s00167-019-05498-z"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00167-019-05498-z'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00167-019-05498-z'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00167-019-05498-z'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00167-019-05498-z'


 

This table displays all metadata directly associated to this object as RDF triples.

201 TRIPLES      20 PREDICATES      61 URIs      16 LITERALS      6 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00167-019-05498-z schema:about anzsrc-for:11
2 anzsrc-for:1103
3 schema:author Ne92d1d4fe44e4a07994612911839461b
4 schema:citation sg:pub.10.1007/s00167-015-3558-z
5 sg:pub.10.1007/s00167-018-5323-6
6 sg:pub.10.1007/s00167-019-05353-1
7 sg:pub.10.1007/s11999-012-2351-2
8 sg:pub.10.1186/1471-2474-11-258
9 https://app.dimensions.ai/details/publication/pub.1079376835
10 https://app.dimensions.ai/details/publication/pub.1083243814
11 https://app.dimensions.ai/details/publication/pub.1083737573
12 https://doi.org/10.1007/s11999-012-2351-2
13 https://doi.org/10.1016/j.arth.2007.02.012
14 https://doi.org/10.1016/j.arth.2011.03.034
15 https://doi.org/10.1016/j.arth.2014.02.012
16 https://doi.org/10.1016/j.arth.2015.10.015
17 https://doi.org/10.1016/j.arthro.2011.08.301
18 https://doi.org/10.1016/j.jcma.2012.02.016
19 https://doi.org/10.1016/j.spinee.2011.04.025
20 https://doi.org/10.1016/j.spinee.2015.01.030
21 https://doi.org/10.1016/j.wneu.2014.12.033
22 https://doi.org/10.1080/17453670710015229
23 https://doi.org/10.1097/00003086-197711000-00033
24 https://doi.org/10.1097/brs.0000000000000015
25 https://doi.org/10.1097/brs.0b013e3181ff2cb1
26 https://doi.org/10.1097/brs.0b013e318285b219
27 https://doi.org/10.1111/j.1365-2125.2007.02897.x
28 https://doi.org/10.1111/os.12356
29 https://doi.org/10.1302/0301-620x.71b5.2584249
30 https://doi.org/10.1302/0301-620x.71b5.2584250
31 https://doi.org/10.1302/0301-620x.95b11.33135
32 https://doi.org/10.2106/00004623-200205000-00009
33 https://doi.org/10.2106/jbjs.15.00988
34 https://doi.org/10.2106/jbjs.g.01570
35 https://doi.org/10.2106/jbjs.j.00772
36 https://doi.org/10.22038/abjs.2015.3938
37 https://doi.org/10.3109/17453674.2013.831320
38 https://doi.org/10.3109/17453679108994458
39 https://doi.org/10.3171/2015.7.focus15258
40 https://doi.org/10.5371/hp.2018.30.1.37
41 schema:datePublished 2019-04-09
42 schema:datePublishedReg 2019-04-09
43 schema:description PURPOSE: A frequent reason for revision surgery after total knee arthroplasty (TKA) and unicompartmental knee arthroplasty (UKA) is periprosthetic joint infection (PJI). The efficacy of intrawound VP in preventing PJI after primary TKA or UKA is rarely reported. The purpose of this study was to investigate the efficacy and side effects of local high-dose VP application to the joint to prevent PJI in TKA and UKA. METHODS: From 2010 to 2017, 166 consecutive patients that underwent primary TKA or UKA were enrolled. Seventy-five patients (92 knees) did not receive VP (control group), while 90 patients (110 knees, VP group) received VP (intrawound, 1 g) before capsule closure during TKA and UKA. Aseptic wound complications, such as skin erosion, wound dehiscence, and prolonged wound healing, were evaluated within 3 months post-operatively. PJI was assessed within a year post-operatively. RESULTS: Seven patients (7.6%) in the control group and five patients (4.5%) in the VP group had PJI. No significant differences existed in the PJI rates between the groups. Aseptic operative wound complications occurred in 4 patients (4.3%) and 13 patients (11.8%), whereas prolonged operative wound healing occurred in 3 patients (3.3%) and 14 patients (12.7%) of patients in the control and VP group, respectively. Operative wound complications were significantly frequent in the VP group. CONCLUSIONS: Intrawound VP administration does not decrease PJI occurrence in primary TKA and significantly causes aseptic wound complications. The use of intrawound VP for the prevention of PJI after primary TKA and UKA is not recommended. LEVEL OF EVIDENCE: Level II.
44 schema:genre research_article
45 schema:inLanguage en
46 schema:isAccessibleForFree false
47 schema:isPartOf sg:journal.1104512
48 schema:name Intrawound vancomycin powder increases post-operative wound complications and does not decrease periprosthetic joint infection in primary total and unicompartmental knee arthroplasties.
49 schema:productId N2801decd1e004e06bc7b70e71aa4885d
50 N764c523e3945414bbf3a59149b6c9778
51 Ncdb95f5de46b46679c8737e9eb47fc0a
52 Nf05c86e2ecfd4076a39878e28e464780
53 schema:sameAs https://app.dimensions.ai/details/publication/pub.1113328002
54 https://doi.org/10.1007/s00167-019-05498-z
55 schema:sdDatePublished 2019-04-15T09:01
56 schema:sdLicense https://scigraph.springernature.com/explorer/license/
57 schema:sdPublisher N6482b12e0604445a903f54b7a43f7eb1
58 schema:url http://link.springer.com/10.1007/s00167-019-05498-z
59 sgo:license sg:explorer/license/
60 sgo:sdDataset articles
61 rdf:type schema:ScholarlyArticle
62 N0a4eac66517d49b79a01dad1166dfd45 schema:affiliation https://www.grid.ac/institutes/grid.411951.9
63 schema:familyName Nishikino
64 schema:givenName Shoichi
65 rdf:type schema:Person
66 N124ed4699bfb49c5bb0f5f4dbb1a1802 schema:affiliation https://www.grid.ac/institutes/grid.411951.9
67 schema:familyName Hoshino
68 schema:givenName Hironobu
69 rdf:type schema:Person
70 N2801decd1e004e06bc7b70e71aa4885d schema:name nlm_unique_id
71 schema:value 9314730
72 rdf:type schema:PropertyValue
73 N38a41033f31941cf97d0fbcc5f131b54 rdf:first Nb4349b63cc714a38b001e072e894b57f
74 rdf:rest rdf:nil
75 N3dc72fc5213944b59f3de11934095b97 rdf:first Ne795e61956f34d7a98a0d0fec77c5c43
76 rdf:rest N83c0c95503e8419bab3776946f57ca0a
77 N44c78d03706542cab0f7aab5e924a1a4 rdf:first N0a4eac66517d49b79a01dad1166dfd45
78 rdf:rest Naf4a491ffd74404d8713448c61012b6e
79 N45f6836ac4074d4a91f40333abe8978c schema:affiliation https://www.grid.ac/institutes/grid.411951.9
80 schema:familyName Hotta
81 schema:givenName Kensuke
82 rdf:type schema:Person
83 N6482b12e0604445a903f54b7a43f7eb1 schema:name Springer Nature - SN SciGraph project
84 rdf:type schema:Organization
85 N764c523e3945414bbf3a59149b6c9778 schema:name dimensions_id
86 schema:value pub.1113328002
87 rdf:type schema:PropertyValue
88 N83c0c95503e8419bab3776946f57ca0a rdf:first N124ed4699bfb49c5bb0f5f4dbb1a1802
89 rdf:rest N38a41033f31941cf97d0fbcc5f131b54
90 N962ef54d5fed4fe0b4b3f9ceb4c8d3e1 schema:affiliation https://www.grid.ac/institutes/grid.411951.9
91 schema:familyName Hanada
92 schema:givenName Mitsuru
93 rdf:type schema:Person
94 Naf4a491ffd74404d8713448c61012b6e rdf:first N45f6836ac4074d4a91f40333abe8978c
95 rdf:rest N3dc72fc5213944b59f3de11934095b97
96 Nb4349b63cc714a38b001e072e894b57f schema:affiliation https://www.grid.ac/institutes/grid.411951.9
97 schema:familyName Matsuyama
98 schema:givenName Yukihiro
99 rdf:type schema:Person
100 Ncdb95f5de46b46679c8737e9eb47fc0a schema:name pubmed_id
101 schema:value 30968239
102 rdf:type schema:PropertyValue
103 Ne795e61956f34d7a98a0d0fec77c5c43 schema:affiliation https://www.grid.ac/institutes/grid.411951.9
104 schema:familyName Furuhashi
105 schema:givenName Hiroki
106 rdf:type schema:Person
107 Ne92d1d4fe44e4a07994612911839461b rdf:first N962ef54d5fed4fe0b4b3f9ceb4c8d3e1
108 rdf:rest N44c78d03706542cab0f7aab5e924a1a4
109 Nf05c86e2ecfd4076a39878e28e464780 schema:name doi
110 schema:value 10.1007/s00167-019-05498-z
111 rdf:type schema:PropertyValue
112 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
113 schema:name Medical and Health Sciences
114 rdf:type schema:DefinedTerm
115 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
116 schema:name Clinical Sciences
117 rdf:type schema:DefinedTerm
118 sg:journal.1104512 schema:issn 0942-2056
119 1433-7347
120 schema:name Knee Surgery, Sports Traumatology, Arthroscopy
121 rdf:type schema:Periodical
122 sg:pub.10.1007/s00167-015-3558-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1001983643
123 https://doi.org/10.1007/s00167-015-3558-z
124 rdf:type schema:CreativeWork
125 sg:pub.10.1007/s00167-018-5323-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1111577103
126 https://doi.org/10.1007/s00167-018-5323-6
127 rdf:type schema:CreativeWork
128 sg:pub.10.1007/s00167-019-05353-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1111502297
129 https://doi.org/10.1007/s00167-019-05353-1
130 rdf:type schema:CreativeWork
131 sg:pub.10.1007/s11999-012-2351-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002256629
132 https://doi.org/10.1007/s11999-012-2351-2
133 rdf:type schema:CreativeWork
134 sg:pub.10.1186/1471-2474-11-258 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016697813
135 https://doi.org/10.1186/1471-2474-11-258
136 rdf:type schema:CreativeWork
137 https://app.dimensions.ai/details/publication/pub.1079376835 schema:CreativeWork
138 https://app.dimensions.ai/details/publication/pub.1083243814 schema:CreativeWork
139 https://app.dimensions.ai/details/publication/pub.1083737573 schema:CreativeWork
140 https://doi.org/10.1007/s11999-012-2351-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002256629
141 rdf:type schema:CreativeWork
142 https://doi.org/10.1016/j.arth.2007.02.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040440384
143 rdf:type schema:CreativeWork
144 https://doi.org/10.1016/j.arth.2011.03.034 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018772956
145 rdf:type schema:CreativeWork
146 https://doi.org/10.1016/j.arth.2014.02.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053448582
147 rdf:type schema:CreativeWork
148 https://doi.org/10.1016/j.arth.2015.10.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030061600
149 rdf:type schema:CreativeWork
150 https://doi.org/10.1016/j.arthro.2011.08.301 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045215484
151 rdf:type schema:CreativeWork
152 https://doi.org/10.1016/j.jcma.2012.02.016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045316618
153 rdf:type schema:CreativeWork
154 https://doi.org/10.1016/j.spinee.2011.04.025 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035678956
155 rdf:type schema:CreativeWork
156 https://doi.org/10.1016/j.spinee.2015.01.030 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009312538
157 rdf:type schema:CreativeWork
158 https://doi.org/10.1016/j.wneu.2014.12.033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044737262
159 rdf:type schema:CreativeWork
160 https://doi.org/10.1080/17453670710015229 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037093975
161 rdf:type schema:CreativeWork
162 https://doi.org/10.1097/00003086-197711000-00033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060158111
163 rdf:type schema:CreativeWork
164 https://doi.org/10.1097/brs.0000000000000015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036183899
165 rdf:type schema:CreativeWork
166 https://doi.org/10.1097/brs.0b013e3181ff2cb1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010006142
167 rdf:type schema:CreativeWork
168 https://doi.org/10.1097/brs.0b013e318285b219 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003256400
169 rdf:type schema:CreativeWork
170 https://doi.org/10.1111/j.1365-2125.2007.02897.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1048264439
171 rdf:type schema:CreativeWork
172 https://doi.org/10.1111/os.12356 schema:sameAs https://app.dimensions.ai/details/publication/pub.1093044222
173 rdf:type schema:CreativeWork
174 https://doi.org/10.1302/0301-620x.71b5.2584249 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079066938
175 rdf:type schema:CreativeWork
176 https://doi.org/10.1302/0301-620x.71b5.2584250 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079066950
177 rdf:type schema:CreativeWork
178 https://doi.org/10.1302/0301-620x.95b11.33135 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064887199
179 rdf:type schema:CreativeWork
180 https://doi.org/10.2106/00004623-200205000-00009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068895016
181 rdf:type schema:CreativeWork
182 https://doi.org/10.2106/jbjs.15.00988 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068898223
183 rdf:type schema:CreativeWork
184 https://doi.org/10.2106/jbjs.g.01570 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068900801
185 rdf:type schema:CreativeWork
186 https://doi.org/10.2106/jbjs.j.00772 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068902106
187 rdf:type schema:CreativeWork
188 https://doi.org/10.22038/abjs.2015.3938 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079108632
189 rdf:type schema:CreativeWork
190 https://doi.org/10.3109/17453674.2013.831320 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028881435
191 rdf:type schema:CreativeWork
192 https://doi.org/10.3109/17453679108994458 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022053415
193 rdf:type schema:CreativeWork
194 https://doi.org/10.3171/2015.7.focus15258 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071081837
195 rdf:type schema:CreativeWork
196 https://doi.org/10.5371/hp.2018.30.1.37 schema:sameAs https://app.dimensions.ai/details/publication/pub.1101533265
197 rdf:type schema:CreativeWork
198 https://www.grid.ac/institutes/grid.411951.9 schema:alternateName Hamamatsu University
199 schema:name Department of Orthopaedic Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu, 431-3192, Japan.
200 Department of Orthopaedic Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu, 431-3192, Japan. mitsuruhanada@gmail.com.
201 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...