Comparable bone union progression after opening wedge high tibial osteotomy using allogenous bone chip or tri-calcium phosphate granule: a prospective ... View Full Text


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Article Info

DATE

2018-10-30

AUTHORS

Do-Yoon Lee, Myung Chul Lee, Chul-Won Ha, Hee-Soo Kyung, Chang-Wan Kim, Moon Jong Chang, Hyuk-Soo Han

ABSTRACT

PurposeThe purpose of this study is to compare the progression rate of bone union and clinical outcomes of opening wedge high tibial osteotomy (OWHTO) using allogenous bone chip or tri-calcium phosphate (TCP) granule as bone graft materials. The hypothesis was that the bone union progression in OWHTOs using TCP granule grafts would be comparable to that of OWHTOs using allogenous bone chip grafts.MethodsBetween 2011 and 2013, 54 patients who had undergone OWHTO for genu varum and osteoarthritis were randomized to one of the two groups at five centres. TCP granule was used to fill the defect in 27 patients and lyophilized allogenous bone chip was used in the other 27 patients. The degree of bone union was classified on a five-point scale and evaluated using plain radiographs of the knee at 6 weeks, 3 months, 6 months, and 12 months postoperatively. Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, pain Visual Analogue Scale (VAS) score and complications were also evaluated.ResultsThe highest degree of bone union observed at 6 and 12 months postoperatively was grade 4, and the number of cases of union progression at each time-point was not significantly different between the two groups (p > 0.05). WOMAC and pain VAS scores also showed no differences between the two groups. No complications were observed during the 12-month period following OWHTO in either group.ConclusionOWHTO using TCP granule bone substitute showed similar bone union rates and clinical outcomes compared to allogenous bone chip grafts. TCP granule can be used as bone substitutes instead of allogenous bone chip grafts in OWHTO.Level of evidenceLevel 1. More... »

PAGES

2945-2950

References to SciGraph publications

  • 2014-04-24. Stellenwert der knienahen Osteotomie bei medialer Gonarthrose in DIE ORTHOPÄDIE
  • 2008-11-18. Remodeling potentials of biphasic calcium phosphate granules in open wedge high tibial osteotomy in ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
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  • 2013-09-18. Beta-tricalcium phosphate shows superior absorption rate and osteoconductivity compared to hydroxyapatite in open-wedge high tibial osteotomy in KNEE SURGERY, SPORTS TRAUMATOLOGY, ARTHROSCOPY
  • 2003-09-30. Complications in high tibial (medial opening wedge) osteotomy in ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
  • 2013-08-29. Comparison between Autogenous Bone Graft and Allogenous Cancellous Bone Graft in Medial Open Wedge High Tibial Osteotomy with 2-Year Follow-up in KNEE SURGERY & RELATED RESEARCH
  • 2016-07-01. Early weight bearing versus delayed weight bearing in medial opening wedge high tibial osteotomy: a randomized controlled trial in KNEE SURGERY, SPORTS TRAUMATOLOGY, ARTHROSCOPY
  • 2016-08-24. The role of bone void fillers in medial opening wedge high tibial osteotomy: a systematic review in KNEE SURGERY, SPORTS TRAUMATOLOGY, ARTHROSCOPY
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    http://scigraph.springernature.com/pub.10.1007/s00167-018-5254-2

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    http://dx.doi.org/10.1007/s00167-018-5254-2

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    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/30377715


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    38 schema:description PurposeThe purpose of this study is to compare the progression rate of bone union and clinical outcomes of opening wedge high tibial osteotomy (OWHTO) using allogenous bone chip or tri-calcium phosphate (TCP) granule as bone graft materials. The hypothesis was that the bone union progression in OWHTOs using TCP granule grafts would be comparable to that of OWHTOs using allogenous bone chip grafts.MethodsBetween 2011 and 2013, 54 patients who had undergone OWHTO for genu varum and osteoarthritis were randomized to one of the two groups at five centres. TCP granule was used to fill the defect in 27 patients and lyophilized allogenous bone chip was used in the other 27 patients. The degree of bone union was classified on a five-point scale and evaluated using plain radiographs of the knee at 6 weeks, 3 months, 6 months, and 12 months postoperatively. Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, pain Visual Analogue Scale (VAS) score and complications were also evaluated.ResultsThe highest degree of bone union observed at 6 and 12 months postoperatively was grade 4, and the number of cases of union progression at each time-point was not significantly different between the two groups (p > 0.05). WOMAC and pain VAS scores also showed no differences between the two groups. No complications were observed during the 12-month period following OWHTO in either group.ConclusionOWHTO using TCP granule bone substitute showed similar bone union rates and clinical outcomes compared to allogenous bone chip grafts. TCP granule can be used as bone substitutes instead of allogenous bone chip grafts in OWHTO.Level of evidenceLevel 1.
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