Is a short trial of prone positioning sufficient to predict the improvement in oxygenation in patients with acute respiratory distress ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2001-06

AUTHORS

Laurent Papazian, Marie-Hélène Paladini, Fabienne Bregeon, Laetitia Huiart, Xavier Thirion, Pierre Saux, Yves Jammes, Jean-Pierre Auffray

ABSTRACT

OBJECTIVE: To determine whether a 1-h trial of prone positioning is sufficient to identify responders. DESIGN: Prospective clinical cohort study in a medico-surgical ICU in a teaching hospital. PATIENTS: 49 patients with acute respiratory distress syndrome. INTERVENTIONS: A 6-h period of prone positioning. MEASUREMENTS AND RESULTS: Baseline measurements (blood gas analysis and respiratory parameters) were evaluated in supine position just prior to turning the patients prone. Measurements were then repeated 1 h after the beginning of prone positioning (PP1h) and at the end of the 6-h period of prone positioning (PP6h). The last measurements were performed 1 h after repositioning the patients supine. Prone position induced an increase in the PaO2/FIO2 ratio (p < 0.001). A response (increase in PaO2/FIO2 ratio of at least 20 % at PP1h and/or at PP6h) was observed in 37 of 49 patients (76%). Twenty-seven of these patients (73%) were responders at PP1h while 10 (27%) were responders only at PP6h- In all, two-thirds of the patients were considered persistent responders. However, whereas the PaO2/FIO2 ratio decreased significantly 1 h after repositioning the fast responders supine, the PaO2/ FIO2 ratio remained unchanged after repositioning slow responders. CONCLUSIONS: A short-term trial of prone positioning does not appear a sufficient method to identify patients who would benefit from the postural treatment. More... »

PAGES

1044-1049

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s001340000799

DOI

http://dx.doi.org/10.1007/s001340000799

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1023531767

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11497137


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