Impact of a bicarbonated saline solution on early resuscitation after major burns View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2000-09

AUTHORS

Mette M. Berger, Anne Pictet, Jean-Pierre Revelly, Philippe Frascarolo, René L. Chioléro

ABSTRACT

Objective: The study aimed at assessing the impact of the introduction of a bicarbonated saline solution on total fluid load, weight gain and acid base status during acute burn resuscitation.Design: Based on a retrospective patient record review.Setting: Burn care centre of a surgical ICU in a tertiary university hospital.Patients: Two groups of adult patients (20/20), with thermal burns of 25% or more body surface area were studied.Intervention: Modification of the resuscitation fluid composition from lactated Ringer’s solution (LR: Na 132 mmol/l, Cl 112 mmol/l, 263 mosm/l), to bicarbonated 0.9% saline (BS: Na 180 mmol/l, Cl 154 mmol/l, 340 mosm/l)Methods: Age, weight, burn size and depth, inhalation injury, fluid intakes over 48 h post-injury, plasma sodium, chloride, creatinine, albumin levels, blood gases and ventilation support were recorded.Results: The demographic characteristics of the patients (41±16 years) in the two groups were not different, with severe burns involving 44±17% body surface area. While the total fluid volumes administered did not differ, BS was associated with lower plasma pH, base excess and bicarbonate levels for 24 h and with hyperchloraemia. Clinical evolution did not differ.Conclusions: Using bicarbonated saline solution for resuscitation causes a transient hyperchloraemic dilutional acidosis compared with LR, and has no other detectable clinical impact over the first 10 days after severe burn injury. More... »

PAGES

1382-1385

References to SciGraph publications

  • 1992-01. Burn shock resuscitation in WORLD JOURNAL OF SURGERY
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    URI

    http://scigraph.springernature.com/pub.10.1007/s001340000615

    DOI

    http://dx.doi.org/10.1007/s001340000615

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1029576850

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/11089771


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