Corticosteroid treatment in critically ill patients with severe influenza pneumonia: a propensity score matching study View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-09

AUTHORS

Gerard Moreno, Alejandro Rodríguez, Luis F. Reyes, Josep Gomez, Jordi Sole-Violan, Emili Díaz, María Bodí, Sandra Trefler, Juan Guardiola, Juan C. Yébenes, Alex Soriano, José Garnacho-Montero, Lorenzo Socias, María del Valle Ortíz, Eudald Correig, Judith Marín-Corral, Montserrat Vallverdú-Vidal, Marcos I. Restrepo, Antoni Torres, Ignacio Martín-Loeches, on behalf of the GETGAG Study Group

ABSTRACT

PURPOSE: To determine clinical predictors associated with corticosteroid administration and its association with ICU mortality in critically ill patients with severe influenza pneumonia. METHODS: Secondary analysis of a prospective cohort study of critically ill patients with confirmed influenza pneumonia admitted to 148 ICUs in Spain between June 2009 and April 2014. Patients who received corticosteroid treatment for causes other than viral pneumonia (e.g., refractory septic shock and asthma or chronic obstructive pulmonary disease [COPD] exacerbation) were excluded. Patients with corticosteroid therapy were compared with those without corticosteroid therapy. We use a propensity score (PS) matching analysis to reduce confounding factors. The primary outcome was ICU mortality. Cox proportional hazards and competing risks analysis was performed to assess the impact of corticosteroids on ICU mortality. RESULTS: A total of 1846 patients with primary influenza pneumonia were enrolled. Corticosteroids were administered in 604 (32.7%) patients, with methylprednisolone the most frequently used corticosteroid (578/604 [95.7%]). The median daily dose was equivalent to 80 mg of methylprednisolone (IQR 60-120) for a median duration of 7 days (IQR 5-10). Asthma, COPD, hematological disease, and the need for mechanical ventilation were independently associated with corticosteroid use. Crude ICU mortality was higher in patients who received corticosteroids (27.5%) than in patients who did not receive corticosteroids (18.8%, p < 0.001). After PS matching, corticosteroid use was associated with ICU mortality in the Cox (HR = 1.32 [95% CI 1.08-1.60], p < 0.006) and competing risks analysis (SHR = 1.37 [95% CI 1.12-1.68], p = 0.001). CONCLUSION: Administration of corticosteroids in patients with severe influenza pneumonia is associated with increased ICU mortality, and these agents should not be used as co-adjuvant therapy. More... »

PAGES

1470-1482

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00134-018-5332-4

DOI

http://dx.doi.org/10.1007/s00134-018-5332-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1105976787

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30074052


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Hospital Universitari Joan XXIII de Tarragona", 
          "id": "https://www.grid.ac/institutes/grid.411435.6", 
          "name": [
            "Critical Care Department URV/IISPV/CIBERES, Hospital Universitari de Tarragona Joan XXIII, Mallafr\u00e9 Guasch 4, 43007, Tarragona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Moreno", 
        "givenName": "Gerard", 
        "id": "sg:person.012377120575.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012377120575.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitari Joan XXIII de Tarragona", 
          "id": "https://www.grid.ac/institutes/grid.411435.6", 
          "name": [
            "Critical Care Department URV/IISPV/CIBERES, Hospital Universitari de Tarragona Joan XXIII, Mallafr\u00e9 Guasch 4, 43007, Tarragona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rodr\u00edguez", 
        "givenName": "Alejandro", 
        "id": "sg:person.0654010413.56", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0654010413.56"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of La Sabana", 
          "id": "https://www.grid.ac/institutes/grid.412166.6", 
          "name": [
            "Department of Microbiology, Universidad de La Sabana, Chia, Colombia", 
            "Department of Critical Care Medicine, Clinica Universidad de La Sabana, Chia, Colombia"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Reyes", 
        "givenName": "Luis F.", 
        "id": "sg:person.0731301001.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731301001.39"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitari Joan XXIII de Tarragona", 
          "id": "https://www.grid.ac/institutes/grid.411435.6", 
          "name": [
            "Critical Care Department URV/IISPV/CIBERES, Hospital Universitari de Tarragona Joan XXIII, Mallafr\u00e9 Guasch 4, 43007, Tarragona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gomez", 
        "givenName": "Josep", 
        "id": "sg:person.0656527216.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0656527216.44"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Critical Care Department, Hospital Dr. Negr\u00edn Gran Canaria, Las Palmas, Gran Canaria, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sole-Violan", 
        "givenName": "Jordi", 
        "id": "sg:person.01142573341.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01142573341.81"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital de Sabadell", 
          "id": "https://www.grid.ac/institutes/grid.414560.2", 
          "name": [
            "Critical Care Department/CIBERES, Hospital Parc Taul\u00ed, Sabadell, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "D\u00edaz", 
        "givenName": "Emili", 
        "id": "sg:person.01253612462.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01253612462.12"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitari Joan XXIII de Tarragona", 
          "id": "https://www.grid.ac/institutes/grid.411435.6", 
          "name": [
            "Critical Care Department URV/IISPV/CIBERES, Hospital Universitari de Tarragona Joan XXIII, Mallafr\u00e9 Guasch 4, 43007, Tarragona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bod\u00ed", 
        "givenName": "Mar\u00eda", 
        "id": "sg:person.0726053701.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0726053701.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitari Joan XXIII de Tarragona", 
          "id": "https://www.grid.ac/institutes/grid.411435.6", 
          "name": [
            "Critical Care Department URV/IISPV/CIBERES, Hospital Universitari de Tarragona Joan XXIII, Mallafr\u00e9 Guasch 4, 43007, Tarragona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Trefler", 
        "givenName": "Sandra", 
        "id": "sg:person.01276531413.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01276531413.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Louisville VA Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.413902.d", 
          "name": [
            "Division of Pulmonary, Critical Care and Sleep Medicine, University of Louisville and Robley Rex VA Medical Center, Louisville, KY, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Guardiola", 
        "givenName": "Juan", 
        "id": "sg:person.01002066055.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01002066055.41"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital de Matar\u00f3", 
          "id": "https://www.grid.ac/institutes/grid.414519.c", 
          "name": [
            "Critical Care Department, Hospital de Matar\u00f3, Matar\u00f3, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Y\u00e9benes", 
        "givenName": "Juan C.", 
        "id": "sg:person.01173554365.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01173554365.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Clinic of Barcelona", 
          "id": "https://www.grid.ac/institutes/grid.410458.c", 
          "name": [
            "Hospital Cl\u00ednic Infectious Diseases, Hospital Cl\u00ednic, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Soriano", 
        "givenName": "Alex", 
        "id": "sg:person.01372375034.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01372375034.11"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitario Virgen Macarena", 
          "id": "https://www.grid.ac/institutes/grid.411375.5", 
          "name": [
            "Critical Care Department, Hospital Universitario Virgen Macarena, Instituto de Biomedicina de Sevilla (IBIS), Seville, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Garnacho-Montero", 
        "givenName": "Jos\u00e9", 
        "id": "sg:person.01345240333.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01345240333.20"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Son Llatzer", 
          "id": "https://www.grid.ac/institutes/grid.413457.0", 
          "name": [
            "Critical Care Department, Hospital Son Ll\u00e0tzer, Palma, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Socias", 
        "givenName": "Lorenzo", 
        "id": "sg:person.01336372140.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01336372140.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitario de Burgos", 
          "id": "https://www.grid.ac/institutes/grid.459669.1", 
          "name": [
            "Critical Care Department, Hospital Universitario de Burgos, Burgos, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "del Valle Ort\u00edz", 
        "givenName": "Mar\u00eda", 
        "id": "sg:person.01015710420.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01015710420.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Rovira i Virgili University", 
          "id": "https://www.grid.ac/institutes/grid.410367.7", 
          "name": [
            "Departamento de Bioestad\u00edstica, Universitat Rovira I Virgili, Tarragona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Correig", 
        "givenName": "Eudald", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Del Mar", 
          "id": "https://www.grid.ac/institutes/grid.411142.3", 
          "name": [
            "Critical Care Department, Hospital Del Mar, Research Group in Critical Disorders (GREPAC), IMIM, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mar\u00edn-Corral", 
        "givenName": "Judith", 
        "id": "sg:person.01031226316.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01031226316.41"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Universitari Arnau de Vilanova", 
          "id": "https://www.grid.ac/institutes/grid.411443.7", 
          "name": [
            "Critical Care Department, Hospital Universitari Arnau de Vilanova, Lleida, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Vallverd\u00fa-Vidal", 
        "givenName": "Montserrat", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The University of Texas Health Science Center at San Antonio", 
          "id": "https://www.grid.ac/institutes/grid.267309.9", 
          "name": [
            "South Texas Veterans Health Care System, University of Texas Health Sciences at San Antonio, San Antonio, Texas, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Restrepo", 
        "givenName": "Marcos I.", 
        "id": "sg:person.0577122561.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0577122561.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Hospital Clinic of Barcelona", 
          "id": "https://www.grid.ac/institutes/grid.410458.c", 
          "name": [
            "Hospital Cl\u00ednic de Barcelona, Servei de Pneumologia i Al\u00b7l\u00e8rgia Respirat\u00f2ria, Institut Cl\u00ednic del T\u00f3rax/CIBERES, Barcelona, Spain"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Torres", 
        "givenName": "Antoni", 
        "id": "sg:person.013354236302.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013354236302.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Anaesthesia and Critical Care, St James \u0301s University Hospital, Trinity Centre for Health Sciences, Multidisciplinary Intensive Care Research Organization (MICRO), Dublin, Ireland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mart\u00edn-Loeches", 
        "givenName": "Ignacio", 
        "id": "sg:person.01366266562.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01366266562.86"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "on behalf of the GETGAG Study Group", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1164/rccm.201102-0345ed", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000729231"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/cc10573", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003509946", 
          "https://doi.org/10.1186/cc10573"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0032280", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003553467"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbmt.2010.09.014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004526316"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/cc3921", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004657384", 
          "https://doi.org/10.1186/cc3921"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/cc3921", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004657384", 
          "https://doi.org/10.1186/cc3921"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bcr.02.2010.2708", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004939121"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.10-1160", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006443366"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/cid/ciw353", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008311674"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s13054-015-0764-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010950385", 
          "https://doi.org/10.1186/s13054-015-0764-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s13054-015-0764-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010950385", 
          "https://doi.org/10.1186/s13054-015-0764-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/511159", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011420673"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/infdis/jiu645", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011818528"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/cid/cir398", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011845747"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00134-016-4578-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012856579", 
          "https://doi.org/10.1007/s00134-016-4578-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00134-016-4578-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012856579", 
          "https://doi.org/10.1007/s00134-016-4578-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jac/dkq511", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014166420"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ccm.0b013e31827e83af", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014463755"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ccm.0b013e31827e83af", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014463755"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1440-1843.2010.01874.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014870160"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.medin.2011.11.020", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018648954"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/sim.6602", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019366900"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/cc9324", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020655049", 
          "https://doi.org/10.1186/cc9324"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00134-010-2078-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022758980", 
          "https://doi.org/10.1007/s00134-010-2078-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mcc.0b013e3283427259", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024758760"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mcc.0b013e3283427259", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024758760"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/mcc.0b013e3283427259", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024758760"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/rccm.201101-0110oc", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024968765"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1164/rccm.201101-0135oc", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027580713"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1399-6576.2011.02491.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028326110"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s2213-2600(14)70041-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030941184"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1378/chest.10-1396", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033213216"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jinf.2011.12.010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033697734"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cmi.2015.06.022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034496588"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1155/2013/865635", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037034466"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00134-009-1727-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038309128", 
          "https://doi.org/10.1007/s00134-009-1727-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00134-009-1727-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038309128", 
          "https://doi.org/10.1007/s00134-009-1727-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00134-009-1727-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038309128", 
          "https://doi.org/10.1007/s00134-009-1727-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003246-198510000-00009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039110630"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00003246-198510000-00009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039110630"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/cc10082", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041489584", 
          "https://doi.org/10.1186/cc10082"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jaci.2011.10.024", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043692827"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ccm.0000000000001616", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047542168"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/ccm.0000000000001616", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047542168"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jhin.2016.12.017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048092201"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01709751", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052044737", 
          "https://doi.org/10.1007/bf01709751"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01709751", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052044737", 
          "https://doi.org/10.1007/bf01709751"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/14651858.cd010406.pub2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052338205"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/14651858.cd010406.pub2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052338205"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/irv.12363", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052559275"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/01621459.1999.10474144", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058305593"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1753465810376951", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064075604"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1753465810376951", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064075604"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1183/13993003.00791-2016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084249632"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1183/13993003.00791-2016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084249632"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1183/13993003.00791-2016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084249632"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/irv.12456", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085117315"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.medin.2018.02.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1101560758"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.medin.2018.02.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1101560758"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-09", 
    "datePublishedReg": "2018-09-01", 
    "description": "PURPOSE: To determine clinical predictors associated with corticosteroid administration and its association with ICU mortality in critically ill patients with severe influenza pneumonia.\nMETHODS: Secondary analysis of a prospective cohort study of critically ill patients with confirmed influenza pneumonia admitted to 148 ICUs in Spain between June 2009 and April 2014. Patients who received corticosteroid treatment for causes other than viral pneumonia (e.g., refractory septic shock and asthma or chronic obstructive pulmonary disease [COPD] exacerbation) were excluded. Patients with corticosteroid therapy were compared with those without corticosteroid therapy. We use a propensity score (PS) matching analysis to reduce confounding factors. The primary outcome was ICU mortality. Cox proportional hazards and competing risks analysis was performed to assess the impact of corticosteroids on ICU mortality.\nRESULTS: A total of 1846 patients with primary influenza pneumonia were enrolled. Corticosteroids were administered in 604 (32.7%) patients, with methylprednisolone the most frequently used corticosteroid (578/604 [95.7%]). The median daily dose was equivalent to 80\u00a0mg of methylprednisolone (IQR 60-120) for a median duration of 7\u00a0days (IQR 5-10). Asthma, COPD, hematological disease, and the need for mechanical ventilation were independently associated with corticosteroid use. Crude ICU mortality was higher in patients who received corticosteroids (27.5%) than in patients who did not receive corticosteroids (18.8%, p\u2009<\u20090.001). After PS matching, corticosteroid use was associated with ICU mortality in the Cox (HR\u2009=\u20091.32 [95% CI 1.08-1.60], p\u2009<\u20090.006) and competing risks analysis (SHR\u2009=\u20091.37 [95% CI 1.12-1.68], p\u2009=\u20090.001).\nCONCLUSION: Administration of corticosteroids in patients with severe influenza pneumonia is associated with increased ICU mortality, and these agents should not be used as co-adjuvant therapy.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00134-018-5332-4", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1313639", 
        "issn": [
          "0342-4642", 
          "1432-1238"
        ], 
        "name": "Intensive Care Medicine", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "9", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "44"
      }
    ], 
    "name": "Corticosteroid treatment in critically ill patients with severe influenza pneumonia: a propensity score matching study", 
    "pagination": "1470-1482", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "7200ced1a93065d15d11cbf58e21297153cf9f9d738125c22c8475785ce9fac2"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30074052"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "7704851"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00134-018-5332-4"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1105976787"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00134-018-5332-4", 
      "https://app.dimensions.ai/details/publication/pub.1105976787"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T13:26", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8659_00000555.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2Fs00134-018-5332-4"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00134-018-5332-4'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00134-018-5332-4'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00134-018-5332-4'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00134-018-5332-4'


 

This table displays all metadata directly associated to this object as RDF triples.

384 TRIPLES      21 PREDICATES      72 URIs      21 LITERALS      9 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00134-018-5332-4 schema:about anzsrc-for:11
2 anzsrc-for:1103
3 schema:author N6f911adc17cf49728d25ceb034fe40a7
4 schema:citation sg:pub.10.1007/bf01709751
5 sg:pub.10.1007/s00134-009-1727-6
6 sg:pub.10.1007/s00134-010-2078-z
7 sg:pub.10.1007/s00134-016-4578-y
8 sg:pub.10.1186/cc10082
9 sg:pub.10.1186/cc10573
10 sg:pub.10.1186/cc3921
11 sg:pub.10.1186/cc9324
12 sg:pub.10.1186/s13054-015-0764-5
13 https://doi.org/10.1002/14651858.cd010406.pub2
14 https://doi.org/10.1002/sim.6602
15 https://doi.org/10.1016/j.bbmt.2010.09.014
16 https://doi.org/10.1016/j.cmi.2015.06.022
17 https://doi.org/10.1016/j.jaci.2011.10.024
18 https://doi.org/10.1016/j.jhin.2016.12.017
19 https://doi.org/10.1016/j.jinf.2011.12.010
20 https://doi.org/10.1016/j.medin.2011.11.020
21 https://doi.org/10.1016/j.medin.2018.02.002
22 https://doi.org/10.1016/s2213-2600(14)70041-4
23 https://doi.org/10.1080/01621459.1999.10474144
24 https://doi.org/10.1086/511159
25 https://doi.org/10.1093/cid/cir398
26 https://doi.org/10.1093/cid/ciw353
27 https://doi.org/10.1093/infdis/jiu645
28 https://doi.org/10.1093/jac/dkq511
29 https://doi.org/10.1097/00003246-198510000-00009
30 https://doi.org/10.1097/ccm.0000000000001616
31 https://doi.org/10.1097/ccm.0b013e31827e83af
32 https://doi.org/10.1097/mcc.0b013e3283427259
33 https://doi.org/10.1111/irv.12363
34 https://doi.org/10.1111/irv.12456
35 https://doi.org/10.1111/j.1399-6576.2011.02491.x
36 https://doi.org/10.1111/j.1440-1843.2010.01874.x
37 https://doi.org/10.1136/bcr.02.2010.2708
38 https://doi.org/10.1155/2013/865635
39 https://doi.org/10.1164/rccm.201101-0110oc
40 https://doi.org/10.1164/rccm.201101-0135oc
41 https://doi.org/10.1164/rccm.201102-0345ed
42 https://doi.org/10.1177/1753465810376951
43 https://doi.org/10.1183/13993003.00791-2016
44 https://doi.org/10.1371/journal.pone.0032280
45 https://doi.org/10.1378/chest.10-1160
46 https://doi.org/10.1378/chest.10-1396
47 schema:datePublished 2018-09
48 schema:datePublishedReg 2018-09-01
49 schema:description PURPOSE: To determine clinical predictors associated with corticosteroid administration and its association with ICU mortality in critically ill patients with severe influenza pneumonia. METHODS: Secondary analysis of a prospective cohort study of critically ill patients with confirmed influenza pneumonia admitted to 148 ICUs in Spain between June 2009 and April 2014. Patients who received corticosteroid treatment for causes other than viral pneumonia (e.g., refractory septic shock and asthma or chronic obstructive pulmonary disease [COPD] exacerbation) were excluded. Patients with corticosteroid therapy were compared with those without corticosteroid therapy. We use a propensity score (PS) matching analysis to reduce confounding factors. The primary outcome was ICU mortality. Cox proportional hazards and competing risks analysis was performed to assess the impact of corticosteroids on ICU mortality. RESULTS: A total of 1846 patients with primary influenza pneumonia were enrolled. Corticosteroids were administered in 604 (32.7%) patients, with methylprednisolone the most frequently used corticosteroid (578/604 [95.7%]). The median daily dose was equivalent to 80 mg of methylprednisolone (IQR 60-120) for a median duration of 7 days (IQR 5-10). Asthma, COPD, hematological disease, and the need for mechanical ventilation were independently associated with corticosteroid use. Crude ICU mortality was higher in patients who received corticosteroids (27.5%) than in patients who did not receive corticosteroids (18.8%, p < 0.001). After PS matching, corticosteroid use was associated with ICU mortality in the Cox (HR = 1.32 [95% CI 1.08-1.60], p < 0.006) and competing risks analysis (SHR = 1.37 [95% CI 1.12-1.68], p = 0.001). CONCLUSION: Administration of corticosteroids in patients with severe influenza pneumonia is associated with increased ICU mortality, and these agents should not be used as co-adjuvant therapy.
50 schema:genre research_article
51 schema:inLanguage en
52 schema:isAccessibleForFree false
53 schema:isPartOf N180870a48b91440a9b74a0bc2a1fe0b9
54 Nc3501c8c6dde455089a68fa1ecf788dd
55 sg:journal.1313639
56 schema:name Corticosteroid treatment in critically ill patients with severe influenza pneumonia: a propensity score matching study
57 schema:pagination 1470-1482
58 schema:productId N338daec78f654e45839cc6aceffb913f
59 N3e3463277542431e96135e3d934d1120
60 N4398d07629184dd3ac06fab24b674ad7
61 N97d959fbcdf645ae912423216e14f44c
62 Nb650ccc33b094ec18dff9a63ca71a584
63 schema:sameAs https://app.dimensions.ai/details/publication/pub.1105976787
64 https://doi.org/10.1007/s00134-018-5332-4
65 schema:sdDatePublished 2019-04-10T13:26
66 schema:sdLicense https://scigraph.springernature.com/explorer/license/
67 schema:sdPublisher N6d67436372af4625a137f7c496c140b1
68 schema:url http://link.springer.com/10.1007%2Fs00134-018-5332-4
69 sgo:license sg:explorer/license/
70 sgo:sdDataset articles
71 rdf:type schema:ScholarlyArticle
72 N0181909072694802a344254ce058b78e rdf:first N03cd857fa7324075b015c9bfd6efaaf0
73 rdf:rest N94246ae84f6c44e4932cb3c81422fdfd
74 N03cd857fa7324075b015c9bfd6efaaf0 schema:affiliation https://www.grid.ac/institutes/grid.410367.7
75 schema:familyName Correig
76 schema:givenName Eudald
77 rdf:type schema:Person
78 N064e5d5a96c54877b8e0ef9c11e2037f schema:familyName on behalf of the GETGAG Study Group
79 rdf:type schema:Person
80 N072228981f3b4803b431a718cc53739a rdf:first sg:person.01015710420.46
81 rdf:rest N0181909072694802a344254ce058b78e
82 N0efa0715e47f452caf956771a107662a rdf:first sg:person.01173554365.46
83 rdf:rest N448385e2756f406386e34a2e4def9514
84 N180870a48b91440a9b74a0bc2a1fe0b9 schema:issueNumber 9
85 rdf:type schema:PublicationIssue
86 N338daec78f654e45839cc6aceffb913f schema:name nlm_unique_id
87 schema:value 7704851
88 rdf:type schema:PropertyValue
89 N36fb68b4541d48e8b40f6222312cb441 rdf:first sg:person.0731301001.39
90 rdf:rest N3dd65e7b91df4955b11f1b26cfc2f358
91 N3dd65e7b91df4955b11f1b26cfc2f358 rdf:first sg:person.0656527216.44
92 rdf:rest N74f433e95491413793fe8da6ebe2e1ac
93 N3e3463277542431e96135e3d934d1120 schema:name pubmed_id
94 schema:value 30074052
95 rdf:type schema:PropertyValue
96 N4398d07629184dd3ac06fab24b674ad7 schema:name readcube_id
97 schema:value 7200ced1a93065d15d11cbf58e21297153cf9f9d738125c22c8475785ce9fac2
98 rdf:type schema:PropertyValue
99 N448385e2756f406386e34a2e4def9514 rdf:first sg:person.01372375034.11
100 rdf:rest N4ac5e952816a42b5a405357b9b9e3389
101 N4ac5e952816a42b5a405357b9b9e3389 rdf:first sg:person.01345240333.20
102 rdf:rest Nf247b30681fc4810a911843d29ab420c
103 N5b1e67c03e89442da12fb519e112d682 rdf:first sg:person.013354236302.01
104 rdf:rest N74720afa41d84f2eabfd4f61bc28de0b
105 N5f13fdebf0ca4c9e866f4dd75e6caad4 rdf:first sg:person.01253612462.12
106 rdf:rest Nc344748686d34adf852c6c166f6da626
107 N6d67436372af4625a137f7c496c140b1 schema:name Springer Nature - SN SciGraph project
108 rdf:type schema:Organization
109 N6f911adc17cf49728d25ceb034fe40a7 rdf:first sg:person.012377120575.58
110 rdf:rest Na1deae2c934b4501bc0b10a78e343188
111 N74720afa41d84f2eabfd4f61bc28de0b rdf:first sg:person.01366266562.86
112 rdf:rest Na5b51490b154472c96ee65dda74e737f
113 N74f433e95491413793fe8da6ebe2e1ac rdf:first sg:person.01142573341.81
114 rdf:rest N5f13fdebf0ca4c9e866f4dd75e6caad4
115 N8c736f1e25104197ac4680d38b9fd564 schema:name Department of Anaesthesia and Critical Care, St James ́s University Hospital, Trinity Centre for Health Sciences, Multidisciplinary Intensive Care Research Organization (MICRO), Dublin, Ireland
116 rdf:type schema:Organization
117 N94246ae84f6c44e4932cb3c81422fdfd rdf:first sg:person.01031226316.41
118 rdf:rest Ne5158b1597de488aa4ddbc105154b8ae
119 N97d959fbcdf645ae912423216e14f44c schema:name dimensions_id
120 schema:value pub.1105976787
121 rdf:type schema:PropertyValue
122 Na10a2f5b9d2b4e27abbfe5cea3a5eb63 schema:affiliation https://www.grid.ac/institutes/grid.411443.7
123 schema:familyName Vallverdú-Vidal
124 schema:givenName Montserrat
125 rdf:type schema:Person
126 Na1deae2c934b4501bc0b10a78e343188 rdf:first sg:person.0654010413.56
127 rdf:rest N36fb68b4541d48e8b40f6222312cb441
128 Na5b51490b154472c96ee65dda74e737f rdf:first N064e5d5a96c54877b8e0ef9c11e2037f
129 rdf:rest rdf:nil
130 Nb650ccc33b094ec18dff9a63ca71a584 schema:name doi
131 schema:value 10.1007/s00134-018-5332-4
132 rdf:type schema:PropertyValue
133 Nc344748686d34adf852c6c166f6da626 rdf:first sg:person.0726053701.37
134 rdf:rest Nfb759fdea7c441cd91ca01388ff5ae46
135 Nc3501c8c6dde455089a68fa1ecf788dd schema:volumeNumber 44
136 rdf:type schema:PublicationVolume
137 Nc98d66a9b77e44d4b199a9e9bc5133fc rdf:first sg:person.01002066055.41
138 rdf:rest N0efa0715e47f452caf956771a107662a
139 Nd564c93e161a4e1e9cb84b855c69b33c rdf:first sg:person.0577122561.15
140 rdf:rest N5b1e67c03e89442da12fb519e112d682
141 Nd9bfffd12c2744dbbbe04b00a9d8d243 schema:name Critical Care Department, Hospital Dr. Negrín Gran Canaria, Las Palmas, Gran Canaria, Spain
142 rdf:type schema:Organization
143 Ne5158b1597de488aa4ddbc105154b8ae rdf:first Na10a2f5b9d2b4e27abbfe5cea3a5eb63
144 rdf:rest Nd564c93e161a4e1e9cb84b855c69b33c
145 Nf247b30681fc4810a911843d29ab420c rdf:first sg:person.01336372140.28
146 rdf:rest N072228981f3b4803b431a718cc53739a
147 Nfb759fdea7c441cd91ca01388ff5ae46 rdf:first sg:person.01276531413.51
148 rdf:rest Nc98d66a9b77e44d4b199a9e9bc5133fc
149 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
150 schema:name Medical and Health Sciences
151 rdf:type schema:DefinedTerm
152 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
153 schema:name Clinical Sciences
154 rdf:type schema:DefinedTerm
155 sg:journal.1313639 schema:issn 0342-4642
156 1432-1238
157 schema:name Intensive Care Medicine
158 rdf:type schema:Periodical
159 sg:person.01002066055.41 schema:affiliation https://www.grid.ac/institutes/grid.413902.d
160 schema:familyName Guardiola
161 schema:givenName Juan
162 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01002066055.41
163 rdf:type schema:Person
164 sg:person.01015710420.46 schema:affiliation https://www.grid.ac/institutes/grid.459669.1
165 schema:familyName del Valle Ortíz
166 schema:givenName María
167 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01015710420.46
168 rdf:type schema:Person
169 sg:person.01031226316.41 schema:affiliation https://www.grid.ac/institutes/grid.411142.3
170 schema:familyName Marín-Corral
171 schema:givenName Judith
172 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01031226316.41
173 rdf:type schema:Person
174 sg:person.01142573341.81 schema:affiliation Nd9bfffd12c2744dbbbe04b00a9d8d243
175 schema:familyName Sole-Violan
176 schema:givenName Jordi
177 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01142573341.81
178 rdf:type schema:Person
179 sg:person.01173554365.46 schema:affiliation https://www.grid.ac/institutes/grid.414519.c
180 schema:familyName Yébenes
181 schema:givenName Juan C.
182 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01173554365.46
183 rdf:type schema:Person
184 sg:person.012377120575.58 schema:affiliation https://www.grid.ac/institutes/grid.411435.6
185 schema:familyName Moreno
186 schema:givenName Gerard
187 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012377120575.58
188 rdf:type schema:Person
189 sg:person.01253612462.12 schema:affiliation https://www.grid.ac/institutes/grid.414560.2
190 schema:familyName Díaz
191 schema:givenName Emili
192 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01253612462.12
193 rdf:type schema:Person
194 sg:person.01276531413.51 schema:affiliation https://www.grid.ac/institutes/grid.411435.6
195 schema:familyName Trefler
196 schema:givenName Sandra
197 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01276531413.51
198 rdf:type schema:Person
199 sg:person.013354236302.01 schema:affiliation https://www.grid.ac/institutes/grid.410458.c
200 schema:familyName Torres
201 schema:givenName Antoni
202 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013354236302.01
203 rdf:type schema:Person
204 sg:person.01336372140.28 schema:affiliation https://www.grid.ac/institutes/grid.413457.0
205 schema:familyName Socias
206 schema:givenName Lorenzo
207 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01336372140.28
208 rdf:type schema:Person
209 sg:person.01345240333.20 schema:affiliation https://www.grid.ac/institutes/grid.411375.5
210 schema:familyName Garnacho-Montero
211 schema:givenName José
212 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01345240333.20
213 rdf:type schema:Person
214 sg:person.01366266562.86 schema:affiliation N8c736f1e25104197ac4680d38b9fd564
215 schema:familyName Martín-Loeches
216 schema:givenName Ignacio
217 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01366266562.86
218 rdf:type schema:Person
219 sg:person.01372375034.11 schema:affiliation https://www.grid.ac/institutes/grid.410458.c
220 schema:familyName Soriano
221 schema:givenName Alex
222 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01372375034.11
223 rdf:type schema:Person
224 sg:person.0577122561.15 schema:affiliation https://www.grid.ac/institutes/grid.267309.9
225 schema:familyName Restrepo
226 schema:givenName Marcos I.
227 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0577122561.15
228 rdf:type schema:Person
229 sg:person.0654010413.56 schema:affiliation https://www.grid.ac/institutes/grid.411435.6
230 schema:familyName Rodríguez
231 schema:givenName Alejandro
232 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0654010413.56
233 rdf:type schema:Person
234 sg:person.0656527216.44 schema:affiliation https://www.grid.ac/institutes/grid.411435.6
235 schema:familyName Gomez
236 schema:givenName Josep
237 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0656527216.44
238 rdf:type schema:Person
239 sg:person.0726053701.37 schema:affiliation https://www.grid.ac/institutes/grid.411435.6
240 schema:familyName Bodí
241 schema:givenName María
242 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0726053701.37
243 rdf:type schema:Person
244 sg:person.0731301001.39 schema:affiliation https://www.grid.ac/institutes/grid.412166.6
245 schema:familyName Reyes
246 schema:givenName Luis F.
247 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731301001.39
248 rdf:type schema:Person
249 sg:pub.10.1007/bf01709751 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052044737
250 https://doi.org/10.1007/bf01709751
251 rdf:type schema:CreativeWork
252 sg:pub.10.1007/s00134-009-1727-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038309128
253 https://doi.org/10.1007/s00134-009-1727-6
254 rdf:type schema:CreativeWork
255 sg:pub.10.1007/s00134-010-2078-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1022758980
256 https://doi.org/10.1007/s00134-010-2078-z
257 rdf:type schema:CreativeWork
258 sg:pub.10.1007/s00134-016-4578-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1012856579
259 https://doi.org/10.1007/s00134-016-4578-y
260 rdf:type schema:CreativeWork
261 sg:pub.10.1186/cc10082 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041489584
262 https://doi.org/10.1186/cc10082
263 rdf:type schema:CreativeWork
264 sg:pub.10.1186/cc10573 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003509946
265 https://doi.org/10.1186/cc10573
266 rdf:type schema:CreativeWork
267 sg:pub.10.1186/cc3921 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004657384
268 https://doi.org/10.1186/cc3921
269 rdf:type schema:CreativeWork
270 sg:pub.10.1186/cc9324 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020655049
271 https://doi.org/10.1186/cc9324
272 rdf:type schema:CreativeWork
273 sg:pub.10.1186/s13054-015-0764-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010950385
274 https://doi.org/10.1186/s13054-015-0764-5
275 rdf:type schema:CreativeWork
276 https://doi.org/10.1002/14651858.cd010406.pub2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052338205
277 rdf:type schema:CreativeWork
278 https://doi.org/10.1002/sim.6602 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019366900
279 rdf:type schema:CreativeWork
280 https://doi.org/10.1016/j.bbmt.2010.09.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004526316
281 rdf:type schema:CreativeWork
282 https://doi.org/10.1016/j.cmi.2015.06.022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034496588
283 rdf:type schema:CreativeWork
284 https://doi.org/10.1016/j.jaci.2011.10.024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043692827
285 rdf:type schema:CreativeWork
286 https://doi.org/10.1016/j.jhin.2016.12.017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048092201
287 rdf:type schema:CreativeWork
288 https://doi.org/10.1016/j.jinf.2011.12.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033697734
289 rdf:type schema:CreativeWork
290 https://doi.org/10.1016/j.medin.2011.11.020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018648954
291 rdf:type schema:CreativeWork
292 https://doi.org/10.1016/j.medin.2018.02.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1101560758
293 rdf:type schema:CreativeWork
294 https://doi.org/10.1016/s2213-2600(14)70041-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030941184
295 rdf:type schema:CreativeWork
296 https://doi.org/10.1080/01621459.1999.10474144 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058305593
297 rdf:type schema:CreativeWork
298 https://doi.org/10.1086/511159 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011420673
299 rdf:type schema:CreativeWork
300 https://doi.org/10.1093/cid/cir398 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011845747
301 rdf:type schema:CreativeWork
302 https://doi.org/10.1093/cid/ciw353 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008311674
303 rdf:type schema:CreativeWork
304 https://doi.org/10.1093/infdis/jiu645 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011818528
305 rdf:type schema:CreativeWork
306 https://doi.org/10.1093/jac/dkq511 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014166420
307 rdf:type schema:CreativeWork
308 https://doi.org/10.1097/00003246-198510000-00009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039110630
309 rdf:type schema:CreativeWork
310 https://doi.org/10.1097/ccm.0000000000001616 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047542168
311 rdf:type schema:CreativeWork
312 https://doi.org/10.1097/ccm.0b013e31827e83af schema:sameAs https://app.dimensions.ai/details/publication/pub.1014463755
313 rdf:type schema:CreativeWork
314 https://doi.org/10.1097/mcc.0b013e3283427259 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024758760
315 rdf:type schema:CreativeWork
316 https://doi.org/10.1111/irv.12363 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052559275
317 rdf:type schema:CreativeWork
318 https://doi.org/10.1111/irv.12456 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085117315
319 rdf:type schema:CreativeWork
320 https://doi.org/10.1111/j.1399-6576.2011.02491.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1028326110
321 rdf:type schema:CreativeWork
322 https://doi.org/10.1111/j.1440-1843.2010.01874.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1014870160
323 rdf:type schema:CreativeWork
324 https://doi.org/10.1136/bcr.02.2010.2708 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004939121
325 rdf:type schema:CreativeWork
326 https://doi.org/10.1155/2013/865635 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037034466
327 rdf:type schema:CreativeWork
328 https://doi.org/10.1164/rccm.201101-0110oc schema:sameAs https://app.dimensions.ai/details/publication/pub.1024968765
329 rdf:type schema:CreativeWork
330 https://doi.org/10.1164/rccm.201101-0135oc schema:sameAs https://app.dimensions.ai/details/publication/pub.1027580713
331 rdf:type schema:CreativeWork
332 https://doi.org/10.1164/rccm.201102-0345ed schema:sameAs https://app.dimensions.ai/details/publication/pub.1000729231
333 rdf:type schema:CreativeWork
334 https://doi.org/10.1177/1753465810376951 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064075604
335 rdf:type schema:CreativeWork
336 https://doi.org/10.1183/13993003.00791-2016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084249632
337 rdf:type schema:CreativeWork
338 https://doi.org/10.1371/journal.pone.0032280 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003553467
339 rdf:type schema:CreativeWork
340 https://doi.org/10.1378/chest.10-1160 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006443366
341 rdf:type schema:CreativeWork
342 https://doi.org/10.1378/chest.10-1396 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033213216
343 rdf:type schema:CreativeWork
344 https://www.grid.ac/institutes/grid.267309.9 schema:alternateName The University of Texas Health Science Center at San Antonio
345 schema:name South Texas Veterans Health Care System, University of Texas Health Sciences at San Antonio, San Antonio, Texas, USA
346 rdf:type schema:Organization
347 https://www.grid.ac/institutes/grid.410367.7 schema:alternateName Rovira i Virgili University
348 schema:name Departamento de Bioestadística, Universitat Rovira I Virgili, Tarragona, Spain
349 rdf:type schema:Organization
350 https://www.grid.ac/institutes/grid.410458.c schema:alternateName Hospital Clinic of Barcelona
351 schema:name Hospital Clínic Infectious Diseases, Hospital Clínic, Barcelona, Spain
352 Hospital Clínic de Barcelona, Servei de Pneumologia i Al·lèrgia Respiratòria, Institut Clínic del Tórax/CIBERES, Barcelona, Spain
353 rdf:type schema:Organization
354 https://www.grid.ac/institutes/grid.411142.3 schema:alternateName Hospital Del Mar
355 schema:name Critical Care Department, Hospital Del Mar, Research Group in Critical Disorders (GREPAC), IMIM, Barcelona, Spain
356 rdf:type schema:Organization
357 https://www.grid.ac/institutes/grid.411375.5 schema:alternateName Hospital Universitario Virgen Macarena
358 schema:name Critical Care Department, Hospital Universitario Virgen Macarena, Instituto de Biomedicina de Sevilla (IBIS), Seville, Spain
359 rdf:type schema:Organization
360 https://www.grid.ac/institutes/grid.411435.6 schema:alternateName Hospital Universitari Joan XXIII de Tarragona
361 schema:name Critical Care Department URV/IISPV/CIBERES, Hospital Universitari de Tarragona Joan XXIII, Mallafré Guasch 4, 43007, Tarragona, Spain
362 rdf:type schema:Organization
363 https://www.grid.ac/institutes/grid.411443.7 schema:alternateName Hospital Universitari Arnau de Vilanova
364 schema:name Critical Care Department, Hospital Universitari Arnau de Vilanova, Lleida, Spain
365 rdf:type schema:Organization
366 https://www.grid.ac/institutes/grid.412166.6 schema:alternateName University of La Sabana
367 schema:name Department of Critical Care Medicine, Clinica Universidad de La Sabana, Chia, Colombia
368 Department of Microbiology, Universidad de La Sabana, Chia, Colombia
369 rdf:type schema:Organization
370 https://www.grid.ac/institutes/grid.413457.0 schema:alternateName Hospital Son Llatzer
371 schema:name Critical Care Department, Hospital Son Llàtzer, Palma, Spain
372 rdf:type schema:Organization
373 https://www.grid.ac/institutes/grid.413902.d schema:alternateName Louisville VA Medical Center
374 schema:name Division of Pulmonary, Critical Care and Sleep Medicine, University of Louisville and Robley Rex VA Medical Center, Louisville, KY, USA
375 rdf:type schema:Organization
376 https://www.grid.ac/institutes/grid.414519.c schema:alternateName Hospital de Mataró
377 schema:name Critical Care Department, Hospital de Mataró, Mataró, Spain
378 rdf:type schema:Organization
379 https://www.grid.ac/institutes/grid.414560.2 schema:alternateName Hospital de Sabadell
380 schema:name Critical Care Department/CIBERES, Hospital Parc Taulí, Sabadell, Spain
381 rdf:type schema:Organization
382 https://www.grid.ac/institutes/grid.459669.1 schema:alternateName Hospital Universitario de Burgos
383 schema:name Critical Care Department, Hospital Universitario de Burgos, Burgos, Spain
384 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...