Short-course antibiotic therapy for critically ill patients treated for postoperative intra-abdominal infection: the DURAPOP randomised clinical trial View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2018-03

AUTHORS

Philippe Montravers, Florence Tubach, Thomas Lescot, Benoit Veber, Marina Esposito-Farèse, Philippe Seguin, Catherine Paugam, Alain Lepape, Claude Meistelman, Joel Cousson, Antoine Tesniere, Gaetan Plantefeve, Gilles Blasco, Karim Asehnoune, Samir Jaber, Sigismond Lasocki, Herve Dupont, For the DURAPOP Trial Group

ABSTRACT

PURPOSE: Shortening the duration of antibiotic therapy (ABT) is a key measure in antimicrobial stewardship. The optimal duration of ABT for treatment of postoperative intra-abdominal infections (PIAI) in critically ill patients is unknown. METHODS: A multicentre prospective randomised trial conducted in 21 French intensive care units (ICU) between May 2011 and February 2015 compared the efficacy and safety of 8-day versus 15-day antibiotic therapy in critically ill patients with PIAI. Among 410 eligible patients (adequate source control and ABT on day 0), 249 patients were randomly assigned on day 8 to either stop ABT immediately (n = 126) or to continue ABT until day 15 (n = 123). The primary endpoint was the number of antibiotic-free days between randomisation (day 8) and day 28. Secondary outcomes were death, ICU and hospital length of stay, emergence of multidrug-resistant (MDR) bacteria and reoperation rate, with 45-day follow-up. RESULTS: Patients treated for 8 days had a higher median number of antibiotic-free days than those treated for 15 days (15 [6-20] vs 12 [6-13] days, respectively; P < 0.0001) (Wilcoxon rank difference 4.99 days [95% CI 2.99-6.00; P < 0.0001). Equivalence was established in terms of 45-day mortality (rate difference 0.038, 95% CI - 0.013 to 0.061). Treatments did not differ in terms of ICU and hospital length of stay, emergence of MDR bacteria or reoperation rate, while subsequent drainages between day 8 and day 45 were observed following short-course ABT (P = 0.041). CONCLUSION: Short-course antibiotic therapy in critically ill ICU patients with PIAI reduces antibiotic exposure. Continuation of treatment until day 15 is not associated with any clinical benefit. CLINICALTRIALS. GOV IDENTIFIER: NCT01311765. More... »

PAGES

300-310

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00134-018-5088-x

DOI

http://dx.doi.org/10.1007/s00134-018-5088-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1101223438

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/29484469


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged, 80 and over", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Anti-Bacterial Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Critical Illness", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "France", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Intensive Care Units", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Intraabdominal Infections", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Obesity, Morbid", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prospective Studies", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Bichat-Claude-Bernard", 
          "id": "https://www.grid.ac/institutes/grid.411119.d", 
          "name": [
            "Anaesthesiology and Critical Care Medicine, Bichat-Claude Bernard University Hospital, HUPNSV, AP-HP, INSERM, UMR 1152, Paris Diderot Sorbonne Cite University, Paris, France", 
            "D\u00e9partement d\u2019Anesth\u00e9sie-R\u00e9animation, CHU Bichat Claude Bernard, 48 rue Henri Huchard, 75018, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Montravers", 
        "givenName": "Philippe", 
        "id": "sg:person.0701204327.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0701204327.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "D\u00e9partement de Biostatistique, Sant\u00e9 Publique et Information M\u00e9dicale (BIOSPIM), H\u00f4pital Piti\u00e9-Salp\u00eatri\u00e8re, AP-HP, INSERM, UMR 1123, ECEVE, CIC-EC 1425, Sorbonne Universit\u00e9s, UPMC Univ Paris 06, 75013, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tubach", 
        "givenName": "Florence", 
        "id": "sg:person.0644774462.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0644774462.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Anaesthesiology and Critical Care Medicine, St Antoine Hospital, APHP, Sorbonne Universites, UPMC Univ Paris 06, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lescot", 
        "givenName": "Thomas", 
        "id": "sg:person.01156715673.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01156715673.52"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire De Rouen", 
          "id": "https://www.grid.ac/institutes/grid.41724.34", 
          "name": [
            "Pole Anesth\u00e9sie-R\u00e9animation-SAMU, Rouen University Hospital, Rouen, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Veber", 
        "givenName": "Benoit", 
        "id": "sg:person.01171532572.72", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01171532572.72"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "INSERM CIC-EC 1425, Unit\u00e9 de Recherche Clinique, HUPNVS, CHU Bichat-Claude Bernard, APHP, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Esposito-Far\u00e8se", 
        "givenName": "Marina", 
        "id": "sg:person.01351464710.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01351464710.08"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire de Rennes", 
          "id": "https://www.grid.ac/institutes/grid.411154.4", 
          "name": [
            "Department of Anaesthesiology and Surgical Intensive Care Medicine, CHU Rennes, Rennes, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Seguin", 
        "givenName": "Philippe", 
        "id": "sg:person.01155237623.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01155237623.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Anaesthesiology and Surgical Intensive Care Medicine, CHU Beaujon, Clichy, Paris Diderot Sorbonne Cite University, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Paugam", 
        "givenName": "Catherine", 
        "id": "sg:person.0605615757.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0605615757.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Lyon Sud", 
          "id": "https://www.grid.ac/institutes/grid.411430.3", 
          "name": [
            "Intensive Care Unit, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Pierre B\u00e9nite, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lepape", 
        "givenName": "Alain", 
        "id": "sg:person.01227733123.91", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01227733123.91"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire de Nancy", 
          "id": "https://www.grid.ac/institutes/grid.410527.5", 
          "name": [
            "Service d\u2019Anesth\u00e9sie R\u00e9animation, CHU Brabois, Nancy, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Meistelman", 
        "givenName": "Claude", 
        "id": "sg:person.01140045017.72", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01140045017.72"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire De Reims", 
          "id": "https://www.grid.ac/institutes/grid.139510.f", 
          "name": [
            "P\u00f4le Anesth\u00e9sie-R\u00e9animation, CHU Reims, Reims, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Cousson", 
        "givenName": "Joel", 
        "id": "sg:person.01021571710.59", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01021571710.59"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Surgical Intensive Care Unit, CHU Cochin, Paris Descartes University, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tesniere", 
        "givenName": "Antoine", 
        "id": "sg:person.0633035766.57", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0633035766.57"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Victor Dupouy", 
          "id": "https://www.grid.ac/institutes/grid.414474.6", 
          "name": [
            "R\u00e9animation Polyvalente, CH Victor Dupouy, Argenteuil, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Plantefeve", 
        "givenName": "Gaetan", 
        "id": "sg:person.01034252003.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01034252003.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire de Besan\u00e7on", 
          "id": "https://www.grid.ac/institutes/grid.411158.8", 
          "name": [
            "Service d\u2019Anesth\u00e9sie R\u00e9animation Chirurgicale, CHU Besancon, Besan\u00e7on, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Blasco", 
        "givenName": "Gilles", 
        "id": "sg:person.01305320661.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01305320661.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire de Nantes", 
          "id": "https://www.grid.ac/institutes/grid.277151.7", 
          "name": [
            "Service d\u2019Anesth\u00e9sie et R\u00e9animation Chirurgicale, Hotel Dieu, CHU Nantes, Nantes, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Asehnoune", 
        "givenName": "Karim", 
        "id": "sg:person.01152552676.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01152552676.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "H\u00f4pital Saint Eloi", 
          "id": "https://www.grid.ac/institutes/grid.414352.5", 
          "name": [
            "Service d\u2019Anesth\u00e9sie R\u00e9animation, Hopital St Eloi, CHU Montpellier, Montpellier, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jaber", 
        "givenName": "Samir", 
        "id": "sg:person.01113242353.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01113242353.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "D\u00e9partement d\u2019Anesth\u00e9sie R\u00e9animation, CHU Angers, L\u2019UBL, Universit\u00e9 d\u2019Angers, Angers, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lasocki", 
        "givenName": "Sigismond", 
        "id": "sg:person.01070774770.70", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01070774770.70"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre Hospitalier Universitaire D' Amiens", 
          "id": "https://www.grid.ac/institutes/grid.134996.0", 
          "name": [
            "Critical Care Medicine Department, Amiens University Hospital, INSERM U1088, University of Picardy Jules Verne, Amiens, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dupont", 
        "givenName": "Herve", 
        "id": "sg:person.016646675432.92", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016646675432.92"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "For the DURAPOP Trial Group", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1186/1749-7922-9-37", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000113338", 
          "https://doi.org/10.1186/1749-7922-9-37"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(09)61879-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005894149"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jamasurg.2015.4236", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008250894"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa1411162", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010350005"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1469-0691.2006.01507.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011082744"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.accpm.2015.03.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012379654"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1469-0691.2011.03570.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017701285"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jac/dkp439", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018850166"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jac/dkp439", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018850166"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2334-14-420", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023719723", 
          "https://doi.org/10.1186/1471-2334-14-420"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/cid/ciw118", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027458605"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1155/2010/580340", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031650870", 
          "https://doi.org/10.1155/2010/580340"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s13054-015-0789-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033089880", 
          "https://doi.org/10.1186/s13054-015-0789-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s13054-015-0789-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033089880", 
          "https://doi.org/10.1186/s13054-015-0789-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s13054-015-0789-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033089880", 
          "https://doi.org/10.1186/s13054-015-0789-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/cc13082", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035292018", 
          "https://doi.org/10.1186/cc13082"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/cid/civ495", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037090741"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00104-015-0106-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037670373", 
          "https://doi.org/10.1007/s00104-015-0106-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.1993.03510240069035", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037698576"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/649554", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040116551"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.290.19.2588", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040307087"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/cc7931", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042966664", 
          "https://doi.org/10.1186/cc7931"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jac/dkr308", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045348566"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aac.01614-13", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045788015"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s13054-016-1267-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047514723", 
          "https://doi.org/10.1186/s13054-016-1267-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s13054-016-1267-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047514723", 
          "https://doi.org/10.1186/s13054-016-1267-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/cid/civ097", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050478797"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/sur.2013.045", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051852428"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01709751", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052044737", 
          "https://doi.org/10.1007/bf01709751"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01709751", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052044737", 
          "https://doi.org/10.1007/bf01709751"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jac/dks523", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052569307"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.275.3.234", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054159838"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/sur.2012.084", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059312402"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.18637/jss.v045.i03", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068672674"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/sur.2016.261", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079391952"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s13017-017-0132-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085126403", 
          "https://doi.org/10.1186/s13017-017-0132-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s13017-017-0132-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085126403", 
          "https://doi.org/10.1186/s13017-017-0132-7"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2018-03", 
    "datePublishedReg": "2018-03-01", 
    "description": "PURPOSE: Shortening the duration of antibiotic therapy (ABT) is a key measure in antimicrobial stewardship. The optimal duration of ABT for treatment of postoperative intra-abdominal infections (PIAI) in critically ill patients is unknown.\nMETHODS: A multicentre prospective randomised trial conducted in 21 French intensive care units (ICU) between May 2011 and February 2015 compared the efficacy and safety of 8-day versus 15-day antibiotic therapy in critically ill patients with PIAI. Among 410 eligible patients (adequate source control and ABT on day 0), 249 patients were randomly assigned on day 8 to either stop ABT immediately (n\u00a0=\u00a0126) or to continue ABT until day 15 (n\u00a0=\u00a0123). The primary endpoint was the number of antibiotic-free days between randomisation (day 8) and day 28. Secondary outcomes were death, ICU and hospital length of stay, emergence of multidrug-resistant (MDR) bacteria and reoperation rate, with 45-day follow-up.\nRESULTS: Patients treated for 8\u00a0days had a higher median number of antibiotic-free days than those treated for 15\u00a0days (15 [6-20] vs 12 [6-13] days, respectively; P\u00a0<\u00a00.0001) (Wilcoxon rank difference 4.99\u00a0days [95% CI 2.99-6.00; P\u00a0<\u00a00.0001). Equivalence was established in terms of 45-day mortality (rate difference 0.038, 95% CI -\u00a00.013 to 0.061). Treatments did not differ in terms of ICU and hospital length of stay, emergence of MDR bacteria or reoperation rate, while subsequent drainages between day 8 and day 45 were observed following short-course ABT (P\u00a0=\u00a00.041).\nCONCLUSION: Short-course antibiotic therapy in critically ill ICU patients with PIAI reduces antibiotic exposure. Continuation of treatment until day 15 is not associated with any clinical benefit. CLINICALTRIALS.\nGOV IDENTIFIER: NCT01311765.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00134-018-5088-x", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1313639", 
        "issn": [
          "0342-4642", 
          "1432-1238"
        ], 
        "name": "Intensive Care Medicine", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "44"
      }
    ], 
    "name": "Short-course antibiotic therapy for critically ill patients treated for postoperative intra-abdominal infection: the DURAPOP randomised clinical trial", 
    "pagination": "300-310", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "35a731b4a89bb79011bd0888c5669bfe096abbd67d667e9e15eef457500c77f7"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "29484469"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "7704851"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00134-018-5088-x"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1101223438"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00134-018-5088-x", 
      "https://app.dimensions.ai/details/publication/pub.1101223438"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T10:01", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000347_0000000347/records_89819_00000003.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs00134-018-5088-x"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00134-018-5088-x'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00134-018-5088-x'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00134-018-5088-x'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00134-018-5088-x'


 

This table displays all metadata directly associated to this object as RDF triples.

383 TRIPLES      21 PREDICATES      73 URIs      34 LITERALS      22 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00134-018-5088-x schema:about N029a534c685b4a8696e8ed1e49105307
2 N0c6e573cf1ec484082341f5bf22f4e28
3 N1f81ab8d6b114a3892506c9b3636ac97
4 N251a44c36e3f4caf91d769ef3b708836
5 N2d63f24a9a624fb78717e182dd7d0654
6 N3cb10f08282d4061b97989aa80981822
7 N5c316663ea724122b1cc8aabb7715dfe
8 N6563c378fb124e6e9fe34e65f8abec5e
9 N805ecb8c87324356ae0e8dcfb84204ac
10 Na8f3940168824a39a16487191eee756b
11 Nce3bbec631484fbfa9023f11291e6fc3
12 Ne9e41befc5b34233985d09d35f97b662
13 Nfb6e8f243867464ea298e7a3858d972d
14 anzsrc-for:11
15 anzsrc-for:1103
16 schema:author Nfb9831f833a2442190f721e6a915b0a5
17 schema:citation sg:pub.10.1007/bf01709751
18 sg:pub.10.1007/s00104-015-0106-9
19 sg:pub.10.1155/2010/580340
20 sg:pub.10.1186/1471-2334-14-420
21 sg:pub.10.1186/1749-7922-9-37
22 sg:pub.10.1186/cc13082
23 sg:pub.10.1186/cc7931
24 sg:pub.10.1186/s13017-017-0132-7
25 sg:pub.10.1186/s13054-015-0789-9
26 sg:pub.10.1186/s13054-016-1267-8
27 https://doi.org/10.1001/jama.1993.03510240069035
28 https://doi.org/10.1001/jama.275.3.234
29 https://doi.org/10.1001/jama.290.19.2588
30 https://doi.org/10.1001/jamasurg.2015.4236
31 https://doi.org/10.1016/j.accpm.2015.03.005
32 https://doi.org/10.1016/s0140-6736(09)61879-1
33 https://doi.org/10.1056/nejmoa1411162
34 https://doi.org/10.1086/649554
35 https://doi.org/10.1089/sur.2012.084
36 https://doi.org/10.1089/sur.2013.045
37 https://doi.org/10.1089/sur.2016.261
38 https://doi.org/10.1093/cid/civ097
39 https://doi.org/10.1093/cid/civ495
40 https://doi.org/10.1093/cid/ciw118
41 https://doi.org/10.1093/jac/dkp439
42 https://doi.org/10.1093/jac/dkr308
43 https://doi.org/10.1093/jac/dks523
44 https://doi.org/10.1111/j.1469-0691.2006.01507.x
45 https://doi.org/10.1111/j.1469-0691.2011.03570.x
46 https://doi.org/10.1128/aac.01614-13
47 https://doi.org/10.18637/jss.v045.i03
48 schema:datePublished 2018-03
49 schema:datePublishedReg 2018-03-01
50 schema:description PURPOSE: Shortening the duration of antibiotic therapy (ABT) is a key measure in antimicrobial stewardship. The optimal duration of ABT for treatment of postoperative intra-abdominal infections (PIAI) in critically ill patients is unknown. METHODS: A multicentre prospective randomised trial conducted in 21 French intensive care units (ICU) between May 2011 and February 2015 compared the efficacy and safety of 8-day versus 15-day antibiotic therapy in critically ill patients with PIAI. Among 410 eligible patients (adequate source control and ABT on day 0), 249 patients were randomly assigned on day 8 to either stop ABT immediately (n = 126) or to continue ABT until day 15 (n = 123). The primary endpoint was the number of antibiotic-free days between randomisation (day 8) and day 28. Secondary outcomes were death, ICU and hospital length of stay, emergence of multidrug-resistant (MDR) bacteria and reoperation rate, with 45-day follow-up. RESULTS: Patients treated for 8 days had a higher median number of antibiotic-free days than those treated for 15 days (15 [6-20] vs 12 [6-13] days, respectively; P < 0.0001) (Wilcoxon rank difference 4.99 days [95% CI 2.99-6.00; P < 0.0001). Equivalence was established in terms of 45-day mortality (rate difference 0.038, 95% CI - 0.013 to 0.061). Treatments did not differ in terms of ICU and hospital length of stay, emergence of MDR bacteria or reoperation rate, while subsequent drainages between day 8 and day 45 were observed following short-course ABT (P = 0.041). CONCLUSION: Short-course antibiotic therapy in critically ill ICU patients with PIAI reduces antibiotic exposure. Continuation of treatment until day 15 is not associated with any clinical benefit. CLINICALTRIALS. GOV IDENTIFIER: NCT01311765.
51 schema:genre research_article
52 schema:inLanguage en
53 schema:isAccessibleForFree false
54 schema:isPartOf N7ef6f7542e804597969a1e3df4fda2c8
55 Ne8a026048fad4e3eb8f85eb34be3e5ea
56 sg:journal.1313639
57 schema:name Short-course antibiotic therapy for critically ill patients treated for postoperative intra-abdominal infection: the DURAPOP randomised clinical trial
58 schema:pagination 300-310
59 schema:productId N7ee8746b09ae4eb4abfa4bc034b17e58
60 N820aa6b3e1684fe286f398defcd3bfba
61 Nb819085004a543ec882f2c96d1aac4fe
62 Nc5316fd72fde4a8a80de84e8dc67508c
63 Nf7112368b37c4737b2dc623616289a1a
64 schema:sameAs https://app.dimensions.ai/details/publication/pub.1101223438
65 https://doi.org/10.1007/s00134-018-5088-x
66 schema:sdDatePublished 2019-04-11T10:01
67 schema:sdLicense https://scigraph.springernature.com/explorer/license/
68 schema:sdPublisher N7cb257d8747c41d2b75f82636513a2df
69 schema:url https://link.springer.com/10.1007%2Fs00134-018-5088-x
70 sgo:license sg:explorer/license/
71 sgo:sdDataset articles
72 rdf:type schema:ScholarlyArticle
73 N029a534c685b4a8696e8ed1e49105307 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
74 schema:name Obesity, Morbid
75 rdf:type schema:DefinedTerm
76 N0c6e573cf1ec484082341f5bf22f4e28 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
77 schema:name Critical Illness
78 rdf:type schema:DefinedTerm
79 N124948165a054ed1a6e94afa0f63f751 rdf:first sg:person.01021571710.59
80 rdf:rest N9fea46fe447f491ca0327c3888bc47bf
81 N13797c142d9845ce8bbfae9cdec906db schema:name Département d’Anesthésie Réanimation, CHU Angers, L’UBL, Université d’Angers, Angers, France
82 rdf:type schema:Organization
83 N1d1e430b408846ccac3135e89fc9c472 rdf:first sg:person.0644774462.29
84 rdf:rest N8c7f23b17c9947738c0e7b80c1b653b8
85 N1f81ab8d6b114a3892506c9b3636ac97 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name Male
87 rdf:type schema:DefinedTerm
88 N20fa64384cf8462389b2d5f8345bcbda rdf:first sg:person.016646675432.92
89 rdf:rest Nc1d1271fb0044b6cad086d510bb844bb
90 N251a44c36e3f4caf91d769ef3b708836 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Aged, 80 and over
92 rdf:type schema:DefinedTerm
93 N2d63f24a9a624fb78717e182dd7d0654 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Intraabdominal Infections
95 rdf:type schema:DefinedTerm
96 N3c24da89a5c54cf2859d94910c1fb1b9 schema:familyName For the DURAPOP Trial Group
97 rdf:type schema:Person
98 N3cb10f08282d4061b97989aa80981822 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Humans
100 rdf:type schema:DefinedTerm
101 N48ad372308c642b1805cbb835baad2d7 rdf:first sg:person.01351464710.08
102 rdf:rest N66d00c666e604efebdd619c607341862
103 N4ca2ebb5cde64c0a8bdce49ccd84f53c schema:name Surgical Intensive Care Unit, CHU Cochin, Paris Descartes University, Paris, France
104 rdf:type schema:Organization
105 N4d3c1730485a40ae9e5ef90e0fa7c5b0 schema:name Department of Anaesthesiology and Surgical Intensive Care Medicine, CHU Beaujon, Clichy, Paris Diderot Sorbonne Cite University, Paris, France
106 rdf:type schema:Organization
107 N4f8c553d05014a06a6f8d987b66d51fd rdf:first sg:person.01034252003.00
108 rdf:rest Ne83b24fd56c74b68839da90662632894
109 N5c316663ea724122b1cc8aabb7715dfe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Prospective Studies
111 rdf:type schema:DefinedTerm
112 N6563c378fb124e6e9fe34e65f8abec5e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Anti-Bacterial Agents
114 rdf:type schema:DefinedTerm
115 N658dcb32e03845d091022f385b5c2233 rdf:first sg:person.01152552676.15
116 rdf:rest Nc1816d27c8f54501a827453196768fe4
117 N66d00c666e604efebdd619c607341862 rdf:first sg:person.01155237623.63
118 rdf:rest N6e9913b1de0b41e3818effd5406d531c
119 N6e9913b1de0b41e3818effd5406d531c rdf:first sg:person.0605615757.15
120 rdf:rest N9780956c0078443d883437fef36581d2
121 N6ff50a2e752d4d2eacdb632ce91bab82 schema:name INSERM CIC-EC 1425, Unité de Recherche Clinique, HUPNVS, CHU Bichat-Claude Bernard, APHP, Paris, France
122 rdf:type schema:Organization
123 N7cb257d8747c41d2b75f82636513a2df schema:name Springer Nature - SN SciGraph project
124 rdf:type schema:Organization
125 N7ee8746b09ae4eb4abfa4bc034b17e58 schema:name doi
126 schema:value 10.1007/s00134-018-5088-x
127 rdf:type schema:PropertyValue
128 N7ef6f7542e804597969a1e3df4fda2c8 schema:issueNumber 3
129 rdf:type schema:PublicationIssue
130 N805ecb8c87324356ae0e8dcfb84204ac schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Intensive Care Units
132 rdf:type schema:DefinedTerm
133 N81148c8c71ea4f1a833124358801dd4d schema:name Department of Anaesthesiology and Critical Care Medicine, St Antoine Hospital, APHP, Sorbonne Universites, UPMC Univ Paris 06, Paris, France
134 rdf:type schema:Organization
135 N820aa6b3e1684fe286f398defcd3bfba schema:name dimensions_id
136 schema:value pub.1101223438
137 rdf:type schema:PropertyValue
138 N8c7f23b17c9947738c0e7b80c1b653b8 rdf:first sg:person.01156715673.52
139 rdf:rest Nceef6211de7943fb893f0b0d40d35f4e
140 N9780956c0078443d883437fef36581d2 rdf:first sg:person.01227733123.91
141 rdf:rest Nca5ab0e075654e7d9e636ae14fb13d99
142 N9fea46fe447f491ca0327c3888bc47bf rdf:first sg:person.0633035766.57
143 rdf:rest N4f8c553d05014a06a6f8d987b66d51fd
144 Na8f3940168824a39a16487191eee756b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Aged
146 rdf:type schema:DefinedTerm
147 Nb819085004a543ec882f2c96d1aac4fe schema:name pubmed_id
148 schema:value 29484469
149 rdf:type schema:PropertyValue
150 Nbac3697684144d09a41df0fa14f0a654 rdf:first sg:person.01070774770.70
151 rdf:rest N20fa64384cf8462389b2d5f8345bcbda
152 Nbce5195fe3dd427bb6353d906631d48a schema:name Département de Biostatistique, Santé Publique et Information Médicale (BIOSPIM), Hôpital Pitié-Salpêtrière, AP-HP, INSERM, UMR 1123, ECEVE, CIC-EC 1425, Sorbonne Universités, UPMC Univ Paris 06, 75013, Paris, France
153 rdf:type schema:Organization
154 Nc1816d27c8f54501a827453196768fe4 rdf:first sg:person.01113242353.35
155 rdf:rest Nbac3697684144d09a41df0fa14f0a654
156 Nc1d1271fb0044b6cad086d510bb844bb rdf:first N3c24da89a5c54cf2859d94910c1fb1b9
157 rdf:rest rdf:nil
158 Nc5316fd72fde4a8a80de84e8dc67508c schema:name readcube_id
159 schema:value 35a731b4a89bb79011bd0888c5669bfe096abbd67d667e9e15eef457500c77f7
160 rdf:type schema:PropertyValue
161 Nca5ab0e075654e7d9e636ae14fb13d99 rdf:first sg:person.01140045017.72
162 rdf:rest N124948165a054ed1a6e94afa0f63f751
163 Nce3bbec631484fbfa9023f11291e6fc3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
164 schema:name Female
165 rdf:type schema:DefinedTerm
166 Nceef6211de7943fb893f0b0d40d35f4e rdf:first sg:person.01171532572.72
167 rdf:rest N48ad372308c642b1805cbb835baad2d7
168 Ne83b24fd56c74b68839da90662632894 rdf:first sg:person.01305320661.21
169 rdf:rest N658dcb32e03845d091022f385b5c2233
170 Ne8a026048fad4e3eb8f85eb34be3e5ea schema:volumeNumber 44
171 rdf:type schema:PublicationVolume
172 Ne9e41befc5b34233985d09d35f97b662 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
173 schema:name Middle Aged
174 rdf:type schema:DefinedTerm
175 Nf7112368b37c4737b2dc623616289a1a schema:name nlm_unique_id
176 schema:value 7704851
177 rdf:type schema:PropertyValue
178 Nfb6e8f243867464ea298e7a3858d972d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
179 schema:name France
180 rdf:type schema:DefinedTerm
181 Nfb9831f833a2442190f721e6a915b0a5 rdf:first sg:person.0701204327.15
182 rdf:rest N1d1e430b408846ccac3135e89fc9c472
183 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
184 schema:name Medical and Health Sciences
185 rdf:type schema:DefinedTerm
186 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
187 schema:name Clinical Sciences
188 rdf:type schema:DefinedTerm
189 sg:journal.1313639 schema:issn 0342-4642
190 1432-1238
191 schema:name Intensive Care Medicine
192 rdf:type schema:Periodical
193 sg:person.01021571710.59 schema:affiliation https://www.grid.ac/institutes/grid.139510.f
194 schema:familyName Cousson
195 schema:givenName Joel
196 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01021571710.59
197 rdf:type schema:Person
198 sg:person.01034252003.00 schema:affiliation https://www.grid.ac/institutes/grid.414474.6
199 schema:familyName Plantefeve
200 schema:givenName Gaetan
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01034252003.00
202 rdf:type schema:Person
203 sg:person.01070774770.70 schema:affiliation N13797c142d9845ce8bbfae9cdec906db
204 schema:familyName Lasocki
205 schema:givenName Sigismond
206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01070774770.70
207 rdf:type schema:Person
208 sg:person.01113242353.35 schema:affiliation https://www.grid.ac/institutes/grid.414352.5
209 schema:familyName Jaber
210 schema:givenName Samir
211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01113242353.35
212 rdf:type schema:Person
213 sg:person.01140045017.72 schema:affiliation https://www.grid.ac/institutes/grid.410527.5
214 schema:familyName Meistelman
215 schema:givenName Claude
216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01140045017.72
217 rdf:type schema:Person
218 sg:person.01152552676.15 schema:affiliation https://www.grid.ac/institutes/grid.277151.7
219 schema:familyName Asehnoune
220 schema:givenName Karim
221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01152552676.15
222 rdf:type schema:Person
223 sg:person.01155237623.63 schema:affiliation https://www.grid.ac/institutes/grid.411154.4
224 schema:familyName Seguin
225 schema:givenName Philippe
226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01155237623.63
227 rdf:type schema:Person
228 sg:person.01156715673.52 schema:affiliation N81148c8c71ea4f1a833124358801dd4d
229 schema:familyName Lescot
230 schema:givenName Thomas
231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01156715673.52
232 rdf:type schema:Person
233 sg:person.01171532572.72 schema:affiliation https://www.grid.ac/institutes/grid.41724.34
234 schema:familyName Veber
235 schema:givenName Benoit
236 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01171532572.72
237 rdf:type schema:Person
238 sg:person.01227733123.91 schema:affiliation https://www.grid.ac/institutes/grid.411430.3
239 schema:familyName Lepape
240 schema:givenName Alain
241 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01227733123.91
242 rdf:type schema:Person
243 sg:person.01305320661.21 schema:affiliation https://www.grid.ac/institutes/grid.411158.8
244 schema:familyName Blasco
245 schema:givenName Gilles
246 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01305320661.21
247 rdf:type schema:Person
248 sg:person.01351464710.08 schema:affiliation N6ff50a2e752d4d2eacdb632ce91bab82
249 schema:familyName Esposito-Farèse
250 schema:givenName Marina
251 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01351464710.08
252 rdf:type schema:Person
253 sg:person.016646675432.92 schema:affiliation https://www.grid.ac/institutes/grid.134996.0
254 schema:familyName Dupont
255 schema:givenName Herve
256 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016646675432.92
257 rdf:type schema:Person
258 sg:person.0605615757.15 schema:affiliation N4d3c1730485a40ae9e5ef90e0fa7c5b0
259 schema:familyName Paugam
260 schema:givenName Catherine
261 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0605615757.15
262 rdf:type schema:Person
263 sg:person.0633035766.57 schema:affiliation N4ca2ebb5cde64c0a8bdce49ccd84f53c
264 schema:familyName Tesniere
265 schema:givenName Antoine
266 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0633035766.57
267 rdf:type schema:Person
268 sg:person.0644774462.29 schema:affiliation Nbce5195fe3dd427bb6353d906631d48a
269 schema:familyName Tubach
270 schema:givenName Florence
271 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0644774462.29
272 rdf:type schema:Person
273 sg:person.0701204327.15 schema:affiliation https://www.grid.ac/institutes/grid.411119.d
274 schema:familyName Montravers
275 schema:givenName Philippe
276 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0701204327.15
277 rdf:type schema:Person
278 sg:pub.10.1007/bf01709751 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052044737
279 https://doi.org/10.1007/bf01709751
280 rdf:type schema:CreativeWork
281 sg:pub.10.1007/s00104-015-0106-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037670373
282 https://doi.org/10.1007/s00104-015-0106-9
283 rdf:type schema:CreativeWork
284 sg:pub.10.1155/2010/580340 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031650870
285 https://doi.org/10.1155/2010/580340
286 rdf:type schema:CreativeWork
287 sg:pub.10.1186/1471-2334-14-420 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023719723
288 https://doi.org/10.1186/1471-2334-14-420
289 rdf:type schema:CreativeWork
290 sg:pub.10.1186/1749-7922-9-37 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000113338
291 https://doi.org/10.1186/1749-7922-9-37
292 rdf:type schema:CreativeWork
293 sg:pub.10.1186/cc13082 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035292018
294 https://doi.org/10.1186/cc13082
295 rdf:type schema:CreativeWork
296 sg:pub.10.1186/cc7931 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042966664
297 https://doi.org/10.1186/cc7931
298 rdf:type schema:CreativeWork
299 sg:pub.10.1186/s13017-017-0132-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085126403
300 https://doi.org/10.1186/s13017-017-0132-7
301 rdf:type schema:CreativeWork
302 sg:pub.10.1186/s13054-015-0789-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033089880
303 https://doi.org/10.1186/s13054-015-0789-9
304 rdf:type schema:CreativeWork
305 sg:pub.10.1186/s13054-016-1267-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047514723
306 https://doi.org/10.1186/s13054-016-1267-8
307 rdf:type schema:CreativeWork
308 https://doi.org/10.1001/jama.1993.03510240069035 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037698576
309 rdf:type schema:CreativeWork
310 https://doi.org/10.1001/jama.275.3.234 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054159838
311 rdf:type schema:CreativeWork
312 https://doi.org/10.1001/jama.290.19.2588 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040307087
313 rdf:type schema:CreativeWork
314 https://doi.org/10.1001/jamasurg.2015.4236 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008250894
315 rdf:type schema:CreativeWork
316 https://doi.org/10.1016/j.accpm.2015.03.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012379654
317 rdf:type schema:CreativeWork
318 https://doi.org/10.1016/s0140-6736(09)61879-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005894149
319 rdf:type schema:CreativeWork
320 https://doi.org/10.1056/nejmoa1411162 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010350005
321 rdf:type schema:CreativeWork
322 https://doi.org/10.1086/649554 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040116551
323 rdf:type schema:CreativeWork
324 https://doi.org/10.1089/sur.2012.084 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059312402
325 rdf:type schema:CreativeWork
326 https://doi.org/10.1089/sur.2013.045 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051852428
327 rdf:type schema:CreativeWork
328 https://doi.org/10.1089/sur.2016.261 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079391952
329 rdf:type schema:CreativeWork
330 https://doi.org/10.1093/cid/civ097 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050478797
331 rdf:type schema:CreativeWork
332 https://doi.org/10.1093/cid/civ495 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037090741
333 rdf:type schema:CreativeWork
334 https://doi.org/10.1093/cid/ciw118 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027458605
335 rdf:type schema:CreativeWork
336 https://doi.org/10.1093/jac/dkp439 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018850166
337 rdf:type schema:CreativeWork
338 https://doi.org/10.1093/jac/dkr308 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045348566
339 rdf:type schema:CreativeWork
340 https://doi.org/10.1093/jac/dks523 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052569307
341 rdf:type schema:CreativeWork
342 https://doi.org/10.1111/j.1469-0691.2006.01507.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1011082744
343 rdf:type schema:CreativeWork
344 https://doi.org/10.1111/j.1469-0691.2011.03570.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1017701285
345 rdf:type schema:CreativeWork
346 https://doi.org/10.1128/aac.01614-13 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045788015
347 rdf:type schema:CreativeWork
348 https://doi.org/10.18637/jss.v045.i03 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068672674
349 rdf:type schema:CreativeWork
350 https://www.grid.ac/institutes/grid.134996.0 schema:alternateName Centre Hospitalier Universitaire D' Amiens
351 schema:name Critical Care Medicine Department, Amiens University Hospital, INSERM U1088, University of Picardy Jules Verne, Amiens, France
352 rdf:type schema:Organization
353 https://www.grid.ac/institutes/grid.139510.f schema:alternateName Centre Hospitalier Universitaire De Reims
354 schema:name Pôle Anesthésie-Réanimation, CHU Reims, Reims, France
355 rdf:type schema:Organization
356 https://www.grid.ac/institutes/grid.277151.7 schema:alternateName Centre Hospitalier Universitaire de Nantes
357 schema:name Service d’Anesthésie et Réanimation Chirurgicale, Hotel Dieu, CHU Nantes, Nantes, France
358 rdf:type schema:Organization
359 https://www.grid.ac/institutes/grid.410527.5 schema:alternateName Centre Hospitalier Universitaire de Nancy
360 schema:name Service d’Anesthésie Réanimation, CHU Brabois, Nancy, France
361 rdf:type schema:Organization
362 https://www.grid.ac/institutes/grid.411119.d schema:alternateName Hôpital Bichat-Claude-Bernard
363 schema:name Anaesthesiology and Critical Care Medicine, Bichat-Claude Bernard University Hospital, HUPNSV, AP-HP, INSERM, UMR 1152, Paris Diderot Sorbonne Cite University, Paris, France
364 Département d’Anesthésie-Réanimation, CHU Bichat Claude Bernard, 48 rue Henri Huchard, 75018, Paris, France
365 rdf:type schema:Organization
366 https://www.grid.ac/institutes/grid.411154.4 schema:alternateName Centre Hospitalier Universitaire de Rennes
367 schema:name Department of Anaesthesiology and Surgical Intensive Care Medicine, CHU Rennes, Rennes, France
368 rdf:type schema:Organization
369 https://www.grid.ac/institutes/grid.411158.8 schema:alternateName Centre Hospitalier Universitaire de Besançon
370 schema:name Service d’Anesthésie Réanimation Chirurgicale, CHU Besancon, Besançon, France
371 rdf:type schema:Organization
372 https://www.grid.ac/institutes/grid.411430.3 schema:alternateName Centre Hospitalier Lyon Sud
373 schema:name Intensive Care Unit, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Pierre Bénite, France
374 rdf:type schema:Organization
375 https://www.grid.ac/institutes/grid.414352.5 schema:alternateName Hôpital Saint Eloi
376 schema:name Service d’Anesthésie Réanimation, Hopital St Eloi, CHU Montpellier, Montpellier, France
377 rdf:type schema:Organization
378 https://www.grid.ac/institutes/grid.414474.6 schema:alternateName Centre Hospitalier Victor Dupouy
379 schema:name Réanimation Polyvalente, CH Victor Dupouy, Argenteuil, France
380 rdf:type schema:Organization
381 https://www.grid.ac/institutes/grid.41724.34 schema:alternateName Centre Hospitalier Universitaire De Rouen
382 schema:name Pole Anesthésie-Réanimation-SAMU, Rouen University Hospital, Rouen, France
383 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...