Critical illness-associated diaphragm weakness View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2017-10

AUTHORS

Martin Dres, Ewan C. Goligher, Leo M. A. Heunks, Laurent J. Brochard

ABSTRACT

Diaphragm weakness is highly prevalent in critically ill patients. It may exist prior to ICU admission and may precipitate the need for mechanical ventilation but it also frequently develops during the ICU stay. Several risk factors for diaphragm weakness have been identified; among them sepsis and mechanical ventilation play central roles. We employ the term critical illness-associated diaphragm weakness to refer to the collective effects of all mechanisms of diaphragm injury and weakness occurring in critically ill patients. Critical illness-associated diaphragm weakness is consistently associated with poor outcomes including increased ICU mortality, difficult weaning, and prolonged duration of mechanical ventilation. Bedside techniques for assessing the respiratory muscles promise to improve detection of diaphragm weakness and enable preventive or curative strategies. Inspiratory muscle training and pharmacological interventions may improve respiratory muscle function but data on clinical outcomes remain limited. More... »

PAGES

1441-1452

References to SciGraph publications

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00134-017-4928-4

    DOI

    http://dx.doi.org/10.1007/s00134-017-4928-4

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1091765651

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/28917004


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