Ontology type: schema:ScholarlyArticle Open Access: True
2008-10-30
AUTHORSBenoît P. Guery, Maiken C. Arendrup, Georg Auzinger, Élie Azoulay, Márcio Borges Sá, Elizabeth M. Johnson, Eckhard Müller, Christian Putensen, Coleman Rotstein, Gabriele Sganga, Mario Venditti, Rafael Zaragoza Crespo, Bart Jan Kullberg
ABSTRACTBackgroundInvasive candidiasis and candidemia are frequently encountered in the nosocomial setting particularly in the intensive care unit (ICU).Objective and methodsTo review the current management of invasive candidiasis and candidemia in non-neutropenic adult ICU patients based on a review of the literature and an European expert panel discussion.Results and conclusionsEmpiric and directed treatment for invasive candidiasis are predicated on the hemodynamic status of the patient. Unstable patients may benefit from broad-spectrum antifungal agents, which can be narrowed once the patient has stabilized and the identity of the infecting species is established. In stable patients, a more classical approach using fluconazole may be satisfactory provided that the patient is not colonized with fluconazole resistant strains or there has been recent past exposure to an azole (<30 days). In contrast, pre-emptive therapy is based on the presence of surrogate markers. More... »
PAGES206
http://scigraph.springernature.com/pub.10.1007/s00134-008-1339-6
DOIhttp://dx.doi.org/10.1007/s00134-008-1339-6
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1053260834
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/18972100
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Clinical Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Amphotericin B",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Antifungal Agents",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Bacteremia",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Candida albicans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Candidiasis",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Fluconazole",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Intensive Care Units",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Infectious Diseases, SGRIVI, Hopital Huriez, CHRU Lille, 59045, Lille Cedex, France",
"id": "http://www.grid.ac/institutes/grid.413875.c",
"name": [
"Infectious Diseases, SGRIVI, Hopital Huriez, CHRU Lille, 59045, Lille Cedex, France"
],
"type": "Organization"
},
"familyName": "Guery",
"givenName": "Beno\u00eet P.",
"id": "sg:person.01237263673.36",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01237263673.36"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Unit of Mycology, Department Bacteriology, Mycology and Parasitology, Statens Serum Institut, Building 43/117, 2300, Copenhagen, Denmark",
"id": "http://www.grid.ac/institutes/grid.6203.7",
"name": [
"Unit of Mycology, Department Bacteriology, Mycology and Parasitology, Statens Serum Institut, Building 43/117, 2300, Copenhagen, Denmark"
],
"type": "Organization"
},
"familyName": "Arendrup",
"givenName": "Maiken C.",
"id": "sg:person.01362121101.61",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01362121101.61"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Liver Intensive Care, Institute of Liver Studies, King\u2019s College Hospital, Denmark Hill, SE5 9RS, London, UK",
"id": "http://www.grid.ac/institutes/grid.46699.34",
"name": [
"Liver Intensive Care, Institute of Liver Studies, King\u2019s College Hospital, Denmark Hill, SE5 9RS, London, UK"
],
"type": "Organization"
},
"familyName": "Auzinger",
"givenName": "Georg",
"id": "sg:person.0606165416.23",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0606165416.23"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Service de R\u00e9animation M\u00e9dicale, H\u00f4pital Saint-Louis, 1, avenue Claude-Bellefaux, 75010, Paris, France",
"id": "http://www.grid.ac/institutes/grid.413328.f",
"name": [
"Service de R\u00e9animation M\u00e9dicale, H\u00f4pital Saint-Louis, 1, avenue Claude-Bellefaux, 75010, Paris, France"
],
"type": "Organization"
},
"familyName": "Azoulay",
"givenName": "\u00c9lie",
"id": "sg:person.01352577613.57",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01352577613.57"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Sepsis Unit, Intensive Care Department, Hospital Son Ll\u00e0tzer, Palma de Mallorca, Spain",
"id": "http://www.grid.ac/institutes/grid.413457.0",
"name": [
"Sepsis Unit, Intensive Care Department, Hospital Son Ll\u00e0tzer, Palma de Mallorca, Spain"
],
"type": "Organization"
},
"familyName": "Borges S\u00e1",
"givenName": "M\u00e1rcio",
"id": "sg:person.0771443013.05",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0771443013.05"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Mycology Reference Laboratory, National Collection of Pathogenic Fungi, The HPA Centre for Infections, HPA South West Laboratory, Myrtle Road, Kingsdown, BS2 8EL, Bristol, UK",
"id": "http://www.grid.ac/institutes/None",
"name": [
"Mycology Reference Laboratory, National Collection of Pathogenic Fungi, The HPA Centre for Infections, HPA South West Laboratory, Myrtle Road, Kingsdown, BS2 8EL, Bristol, UK"
],
"type": "Organization"
},
"familyName": "Johnson",
"givenName": "Elizabeth M.",
"id": "sg:person.01111235702.67",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01111235702.67"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Universit\u00e4tsklinik f\u00fcr An\u00e4sthesiologie, Intensivmedizin und Schmerztherapie, Knappschaftskrankenhaus Bochum, Langendreer, Klinikum der Ruhr-Universit\u00e4t, In der Schornau 23\u201325, 44892, Bochum, Germany",
"id": "http://www.grid.ac/institutes/grid.5570.7",
"name": [
"Universit\u00e4tsklinik f\u00fcr An\u00e4sthesiologie, Intensivmedizin und Schmerztherapie, Knappschaftskrankenhaus Bochum, Langendreer, Klinikum der Ruhr-Universit\u00e4t, In der Schornau 23\u201325, 44892, Bochum, Germany"
],
"type": "Organization"
},
"familyName": "M\u00fcller",
"givenName": "Eckhard",
"id": "sg:person.0631011605.40",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0631011605.40"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Operative Intensivmedizin, Klinik und Poliklinik f\u00fcr An\u00e4sthesiologie und Operative Intensivmedizin, Rheinische-Friedrich-Wilhelms Universit\u00e4t Bonn, Sigmund-Freud Str. 25, 53127, Bonn, Germany",
"id": "http://www.grid.ac/institutes/grid.10388.32",
"name": [
"Operative Intensivmedizin, Klinik und Poliklinik f\u00fcr An\u00e4sthesiologie und Operative Intensivmedizin, Rheinische-Friedrich-Wilhelms Universit\u00e4t Bonn, Sigmund-Freud Str. 25, 53127, Bonn, Germany"
],
"type": "Organization"
},
"familyName": "Putensen",
"givenName": "Christian",
"id": "sg:person.01254022237.37",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01254022237.37"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Division of Infectious Diseases, University Health Network, Toronto General Hospital, NCSB 11-1212, 200 Elizabeth Street, M5G 2C4, Toronto, ON, Canada",
"id": "http://www.grid.ac/institutes/grid.417184.f",
"name": [
"Division of Infectious Diseases, University Health Network, Toronto General Hospital, NCSB 11-1212, 200 Elizabeth Street, M5G 2C4, Toronto, ON, Canada"
],
"type": "Organization"
},
"familyName": "Rotstein",
"givenName": "Coleman",
"id": "sg:person.01015727037.87",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01015727037.87"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Surgery, Division of General Surgery and Organ Transplantation, Policlinico \u2018A Gemelli\u2019, Catholic University, Largo Gemelli, 8, 00168, Rome, Italy",
"id": "http://www.grid.ac/institutes/grid.411075.6",
"name": [
"Department of Surgery, Division of General Surgery and Organ Transplantation, Policlinico \u2018A Gemelli\u2019, Catholic University, Largo Gemelli, 8, 00168, Rome, Italy"
],
"type": "Organization"
},
"familyName": "Sganga",
"givenName": "Gabriele",
"id": "sg:person.01350323553.43",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01350323553.43"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Internal Medicine, Clinical Medicine Department, \u201cLa Sapienza\u201d University, Rome, Viale dell\u2019 Universit\u00e0, 37, 00185, Rome, Italy",
"id": "http://www.grid.ac/institutes/grid.7841.a",
"name": [
"Internal Medicine, Clinical Medicine Department, \u201cLa Sapienza\u201d University, Rome, Viale dell\u2019 Universit\u00e0, 37, 00185, Rome, Italy"
],
"type": "Organization"
},
"familyName": "Venditti",
"givenName": "Mario",
"id": "sg:person.01145560477.09",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01145560477.09"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Secretario GTEI-SEMICYUC, Medicina Intensiva, Hospital Universitario Dr. Peset, Avenida Gaspa Aguilar, 90, 46107, Valencia, Spain",
"id": "http://www.grid.ac/institutes/grid.411289.7",
"name": [
"Secretario GTEI-SEMICYUC, Medicina Intensiva, Hospital Universitario Dr. Peset, Avenida Gaspa Aguilar, 90, 46107, Valencia, Spain"
],
"type": "Organization"
},
"familyName": "Zaragoza Crespo",
"givenName": "Rafael",
"id": "sg:person.01300411126.87",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01300411126.87"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Medicine (463), Nijmegen Institute for Infection, Inflammation, and Immunity (N4i), Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB, Nijmegen, The Netherlands",
"id": "http://www.grid.ac/institutes/grid.5590.9",
"name": [
"Department of Medicine (463), Nijmegen Institute for Infection, Inflammation, and Immunity (N4i), Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB, Nijmegen, The Netherlands"
],
"type": "Organization"
},
"familyName": "Kullberg",
"givenName": "Bart Jan",
"id": "sg:person.01300701764.32",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01300701764.32"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1007/s00134-002-1540-y",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046624930",
"https://doi.org/10.1007/s00134-002-1540-y"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s10096-003-1014-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023315304",
"https://doi.org/10.1007/s10096-003-1014-3"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00134-005-2794-y",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042652182",
"https://doi.org/10.1007/s00134-005-2794-y"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/1471-2334-6-21",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1030116738",
"https://doi.org/10.1186/1471-2334-6-21"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00134-007-0865-y",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004256795",
"https://doi.org/10.1007/s00134-007-0865-y"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s001340050286",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021049647",
"https://doi.org/10.1007/s001340050286"
],
"type": "CreativeWork"
}
],
"datePublished": "2008-10-30",
"datePublishedReg": "2008-10-30",
"description": "BackgroundInvasive candidiasis and candidemia are frequently encountered in the nosocomial setting particularly in the intensive care unit (ICU).Objective and methodsTo review the current management of invasive candidiasis and candidemia in non-neutropenic adult ICU patients based on a review of the literature and an European expert panel discussion.Results and conclusionsEmpiric and directed treatment for invasive candidiasis are predicated on the hemodynamic status of the patient. Unstable patients may benefit from broad-spectrum antifungal agents, which can be narrowed once the patient has stabilized and the identity of the infecting species is established. In stable patients, a more classical approach using fluconazole may be satisfactory provided that the patient is not colonized with fluconazole resistant strains or there has been recent past exposure to an azole (<30\u00a0days). In contrast, pre-emptive therapy is based on the presence of surrogate markers.",
"genre": "article",
"id": "sg:pub.10.1007/s00134-008-1339-6",
"isAccessibleForFree": true,
"isPartOf": [
{
"id": "sg:journal.1313639",
"issn": [
"0342-4642",
"1432-1238"
],
"name": "Intensive Care Medicine",
"publisher": "Springer Nature",
"type": "Periodical"
},
{
"issueNumber": "2",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "35"
}
],
"keywords": [
"intensive care unit",
"invasive candidiasis",
"intensive care unit patients",
"pre-emptive therapy",
"adult ICU patients",
"care unit patients",
"fluconazole-resistant strains",
"hemodynamic status",
"unit patients",
"ICU patients",
"stable patients",
"care unit",
"unstable patients",
"surrogate marker",
"broad-spectrum antifungal agent",
"nosocomial setting",
"patients",
"current management",
"expert panel discussion",
"candidiasis",
"candidemia",
"resistant strains",
"antifungal agents",
"treatment",
"therapy",
"fluconazole",
"management",
"MethodsTo",
"markers",
"exposure",
"panel discussion",
"status",
"review",
"agents",
"azoles",
"setting",
"contrast",
"strains",
"presence",
"objective",
"literature",
"units",
"results",
"Part II",
"discussion",
"approach",
"species",
"identity",
"classical approach"
],
"name": "Management of invasive candidiasis and candidemia in adult non-neutropenic intensive care unit patients: Part II. Treatment",
"pagination": "206",
"productId": [
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1053260834"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s00134-008-1339-6"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"18972100"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s00134-008-1339-6",
"https://app.dimensions.ai/details/publication/pub.1053260834"
],
"sdDataset": "articles",
"sdDatePublished": "2022-08-04T16:58",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-springernature-scigraph/baseset/20220804/entities/gbq_results/article/article_469.jsonl",
"type": "ScholarlyArticle",
"url": "https://doi.org/10.1007/s00134-008-1339-6"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00134-008-1339-6'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00134-008-1339-6'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00134-008-1339-6'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00134-008-1339-6'
This table displays all metadata directly associated to this object as RDF triples.
286 TRIPLES
21 PREDICATES
88 URIs
74 LITERALS
15 BLANK NODES