Hyponatremia in neurological patients: cerebral salt wasting versus inappropriate antidiuretic hormone secretion View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2007-10-19

AUTHORS

Serge Brimioulle, Carlos Orellana-Jimenez, Adel Aminian, Jean-Louis Vincent

ABSTRACT

ObjectiveTo assess whether hyponatremia in acute neurological patients is associated with the syndrome of inappropriate antidiuretic hormone secretion (SIADH) or with the cerebral salt-wasting syndrome (CSWS).DesignClinical, controlled, prospective study.SettingDepartment of intensive care of a tertiary care academic hospital.PatientsForty acute neurological patients with hyponatremia suggesting SIADH or CSWS (20) or with normonatremia (20).InterventionsNone.Measurements and main resultsMeasurement of clinical and biological variables. Measurement of blood, plasma, and red blood cell volumes to discriminate SIADH and CSWS. Renal, adrenal and thyroid functions were normal in all patients. Average blood, plasma, and red blood cell volumes were 54, 37 and 17 ml/kg in control patients and 54, 37 and 18 ml/kg in hyponatremic patients, respectively.ConclusionsThe adequate blood volumes in hyponatremic patients confirm the diagnosis of SIADH and do not support the concept of CSWS. More... »

PAGES

125-131

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00134-007-0905-7

DOI

http://dx.doi.org/10.1007/s00134-007-0905-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1029812871

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/17952405


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