Candidemia and candiduria in critically ill patients admitted to intensive care units in France: incidence, molecular diversity, management and outcome View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2007-10-02

AUTHORS

Marie-Elisabeth Bougnoux, Guillaume Kac, Philippe Aegerter, Christophe d’Enfert, Jean-Yves Fagon, CandiRea Study Group

ABSTRACT

ObjectiveTo determine the concomitant incidence, molecular diversity, management and outcome of nosocomial candidemia and candiduria in intensive care unit (ICU) patients in France.DesignA 1-year prospective observational study in 24 adult ICUs.PatientsTwo hundred and sixty-two patients with nosocomial candidemia and/or candiduria.Measurements and resultsBlood and urine samples were collected when signs of sepsis were present. Antifungal susceptibility of Candida strains was determined; in addition, all blood and 72% of urine C. albicans isolates were analyzed by using multi-locus sequence type (MLST). The mean incidences of candidemia and candiduria were 6.7 and 27.4/1000 admissions, respectively. Eight percent of candiduric patients developed candidemia with the same species. The mean interval between ICU admission and candidemia was 19.0 ± 2.9 days, and 17.2 ± 1.1 days for candiduria. C. albicans and C. glabrata were isolated in 54.2% and 17% of blood and 66.5% and 21.6% of urine Candida-positive cultures, respectively. Fluconazole was the most frequently prescribed agent. In all candidemic patients, the prescribed curative antifungal agent was active in vitro against the responsible identified strain. Crude ICU mortality was 61.8% for candidemic and 31.3% for candiduric patients. Seventy-five percent of the patients were infected with a unique C. albicans strain; cross-transmission between seven patients was suggested in one hospital.ConclusionsCandidemia is late-onset ICU-acquired infection associated with high mortality. No difference in susceptibility and genetic background were found between blood and urine strains of Candida species. More... »

PAGES

292-299

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00134-007-0865-y

DOI

http://dx.doi.org/10.1007/s00134-007-0865-y

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1004256795

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/17909746


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "APACHE", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antifungal Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Candida", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Candidiasis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chi-Square Distribution", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Critical Illness", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cross Infection", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "France", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Incidence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Intensive Care Units", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Microbial Sensitivity Tests", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Outcome Assessment, Health Care", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Risk Factors", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Facult\u00e9 de M\u00e9decine, Universit\u00e9 Ren\u00e9 Descartes, Paris, France", 
          "id": "http://www.grid.ac/institutes/grid.508487.6", 
          "name": [
            "Service de Bact\u00e9riologie, Virologie, Parasitologie et Hygi\u00e8ne, H\u00f4pital Necker-Enfants Malades, 149, rue de S\u00e8vres, 75473, Paris Cedex 15, France", 
            "Laboratoire de Parasitologie\u2013Mycologie, Service de Microbiologie, H\u00f4pital Necker Enfants Malades, Paris, France", 
            "Assistance Publique, H\u00f4pitaux de Paris, Paris, France", 
            "Unit\u00e9 Biologie et Pathog\u00e9nicit\u00e9 Fongiques, INRA USC 2019, Institut Pasteur, Paris, France", 
            "Facult\u00e9 de M\u00e9decine, Universit\u00e9 Ren\u00e9 Descartes, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bougnoux", 
        "givenName": "Marie-Elisabeth", 
        "id": "sg:person.01173731273.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01173731273.36"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Unit\u00e9 d\u2019Hygi\u00e8ne Hospitali\u00e8re, H\u00f4pital Europ\u00e9en Georges Pompidou, Paris, France", 
          "id": "http://www.grid.ac/institutes/grid.414093.b", 
          "name": [
            "Assistance Publique, H\u00f4pitaux de Paris, Paris, France", 
            "Unit\u00e9 d\u2019Hygi\u00e8ne Hospitali\u00e8re, H\u00f4pital Europ\u00e9en Georges Pompidou, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kac", 
        "givenName": "Guillaume", 
        "id": "sg:person.0650775470.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0650775470.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Informatique M\u00e9dicale, H\u00f4pital Ambroise-Par\u00e9, Boulogne Billancourt, France", 
          "id": "http://www.grid.ac/institutes/grid.413756.2", 
          "name": [
            "Assistance Publique, H\u00f4pitaux de Paris, Paris, France", 
            "Informatique M\u00e9dicale, H\u00f4pital Ambroise-Par\u00e9, Boulogne Billancourt, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Aegerter", 
        "givenName": "Philippe", 
        "id": "sg:person.01276432660.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01276432660.25"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Unit\u00e9 Biologie et Pathog\u00e9nicit\u00e9 Fongiques, INRA USC 2019, Institut Pasteur, Paris, France", 
          "id": "http://www.grid.ac/institutes/grid.428999.7", 
          "name": [
            "Unit\u00e9 Biologie et Pathog\u00e9nicit\u00e9 Fongiques, INRA USC 2019, Institut Pasteur, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "d\u2019Enfert", 
        "givenName": "Christophe", 
        "id": "sg:person.0760564474.73", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0760564474.73"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Service de R\u00e9animation M\u00e9dicale, H\u00f4pital Europ\u00e9en Georges Pompidou, Paris, France", 
          "id": "http://www.grid.ac/institutes/grid.414093.b", 
          "name": [
            "Assistance Publique, H\u00f4pitaux de Paris, Paris, France", 
            "Facult\u00e9 de M\u00e9decine, Universit\u00e9 Ren\u00e9 Descartes, Paris, France", 
            "Service de R\u00e9animation M\u00e9dicale, H\u00f4pital Europ\u00e9en Georges Pompidou, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fagon", 
        "givenName": "Jean-Yves", 
        "id": "sg:person.0645764401.56", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0645764401.56"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "CandiRea Study Group", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s00134-002-1540-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046624930", 
          "https://doi.org/10.1007/s00134-002-1540-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00134-003-1807-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024023872", 
          "https://doi.org/10.1007/s00134-003-1807-y"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2007-10-02", 
    "datePublishedReg": "2007-10-02", 
    "description": "ObjectiveTo determine the concomitant incidence, molecular diversity, management and outcome of nosocomial candidemia and candiduria in intensive care unit (ICU) patients in France.DesignA\u00a01-year prospective observational study in 24 adult ICUs.PatientsTwo hundred and sixty-two patients with nosocomial candidemia and/or candiduria.Measurements and resultsBlood and urine samples were collected when signs of sepsis were present. Antifungal susceptibility of Candida strains was determined; in addition, all blood and 72% of urine C.\u00a0albicans isolates were analyzed by using multi-locus sequence type (MLST). The mean incidences of candidemia and candiduria were 6.7 and 27.4/1000 admissions, respectively. Eight percent of candiduric patients developed candidemia with the same species. The mean interval between ICU admission and candidemia was 19.0\u202f\u00b1\u202f2.9 days, and 17.2\u202f\u00b1\u202f1.1 days for candiduria. C.\u00a0albicans and C.\u00a0glabrata were isolated in 54.2% and 17% of blood and 66.5% and 21.6% of urine Candida-positive cultures, respectively. Fluconazole was the most frequently prescribed agent. In all candidemic patients, the prescribed curative antifungal agent was active in vitro against the responsible identified strain. Crude ICU mortality was 61.8% for candidemic and 31.3% for candiduric patients. Seventy-five percent of the patients were infected with a\u00a0unique C.\u00a0albicans strain; cross-transmission between seven patients was suggested in one hospital.ConclusionsCandidemia is late-onset ICU-acquired infection associated with high mortality. No difference in susceptibility and genetic background were found between blood and urine strains of Candida species.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s00134-007-0865-y", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1313639", 
        "issn": [
          "0342-4642", 
          "1432-1238"
        ], 
        "name": "Intensive Care Medicine", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "34"
      }
    ], 
    "keywords": [
      "multi-locus sequence types", 
      "candiduric patients", 
      "nosocomial candidemia", 
      "intensive care unit patients", 
      "Candida-positive cultures", 
      "crude ICU mortality", 
      "prospective observational study", 
      "signs of sepsis", 
      "care unit patients", 
      "intensive care unit", 
      "PatientsTwo hundred", 
      "candidemic patients", 
      "urine strains", 
      "adult ICUs", 
      "ICU admission", 
      "ICU mortality", 
      "unit patients", 
      "ill patients", 
      "care unit", 
      "mean interval", 
      "observational study", 
      "concomitant incidence", 
      "candiduria", 
      "patients", 
      "candidemia", 
      "high mortality", 
      "mean incidence", 
      "albicans isolates", 
      "antifungal susceptibility", 
      "urine samples", 
      "incidence", 
      "Candida species", 
      "blood", 
      "ICU", 
      "admission", 
      "antifungal agents", 
      "Candida strains", 
      "mortality", 
      "sequence types", 
      "outcomes", 
      "genetic background", 
      "days", 
      "sepsis", 
      "percent", 
      "ResultsBlood", 
      "hospital", 
      "ObjectiveTo", 
      "agents", 
      "infection", 
      "DesignA", 
      "susceptibility", 
      "albicans", 
      "fluconazole", 
      "management", 
      "signs", 
      "strains", 
      "glabrata", 
      "isolates", 
      "molecular diversity", 
      "interval", 
      "differences", 
      "study", 
      "background", 
      "C.", 
      "culture", 
      "samples", 
      "addition", 
      "France", 
      "units", 
      "types", 
      "same species", 
      "measurements", 
      "species", 
      "hundreds", 
      "diversity"
    ], 
    "name": "Candidemia and candiduria in critically ill patients admitted to intensive care units in France: incidence, molecular diversity, management and outcome", 
    "pagination": "292-299", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1004256795"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00134-007-0865-y"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "17909746"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00134-007-0865-y", 
      "https://app.dimensions.ai/details/publication/pub.1004256795"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-09-02T15:51", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220902/entities/gbq_results/article/article_439.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s00134-007-0865-y"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00134-007-0865-y'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00134-007-0865-y'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00134-007-0865-y'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00134-007-0865-y'


 

This table displays all metadata directly associated to this object as RDF triples.

270 TRIPLES      21 PREDICATES      121 URIs      111 LITERALS      26 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00134-007-0865-y schema:about N1d2a5674ed8446f48bd55555e9c8a51c
2 N1e7d26ae74914cc5938b1d5ea32b9980
3 N1f694f9f9f6a48d5bda276d454628220
4 N24166dfc11ab4bba86cbb821a7d74dc9
5 N26427674c2b443398b63ce413ca20770
6 N285fee8def15461e9bcf50b4ebdba347
7 N3a0399b67e6341b99ddedea93e14455e
8 N4445e5da81bd4194ba08010e6fb90339
9 N66ed0984229a4968b6f042f87e113510
10 N7038efe46ee04ac8b4b78566e0fd2f5b
11 N8de59619de9149a1b4002942c7d89d45
12 N978cc656a11f44649ff732d6aa9634b6
13 N99805911655d41a382f7b6563cbcdf87
14 Na64f6823f87e4eef890290fa7de28dd4
15 Nb6db50e4ff07471d912297e15a5aac9a
16 Nc2b69cc0a17f426a87faf7c5d77bff2f
17 Nd3e0be2437c14f938ff31a7116f4c3d3
18 Ndaebf41cb4d64abfbf896d17df821216
19 Ne0bac7460eb04cf8acc7c75f1360f314
20 anzsrc-for:11
21 anzsrc-for:1103
22 schema:author N8c87159f01b64a9ca0d2a7cd33b2b988
23 schema:citation sg:pub.10.1007/s00134-002-1540-y
24 sg:pub.10.1007/s00134-003-1807-y
25 schema:datePublished 2007-10-02
26 schema:datePublishedReg 2007-10-02
27 schema:description ObjectiveTo determine the concomitant incidence, molecular diversity, management and outcome of nosocomial candidemia and candiduria in intensive care unit (ICU) patients in France.DesignA 1-year prospective observational study in 24 adult ICUs.PatientsTwo hundred and sixty-two patients with nosocomial candidemia and/or candiduria.Measurements and resultsBlood and urine samples were collected when signs of sepsis were present. Antifungal susceptibility of Candida strains was determined; in addition, all blood and 72% of urine C. albicans isolates were analyzed by using multi-locus sequence type (MLST). The mean incidences of candidemia and candiduria were 6.7 and 27.4/1000 admissions, respectively. Eight percent of candiduric patients developed candidemia with the same species. The mean interval between ICU admission and candidemia was 19.0 ± 2.9 days, and 17.2 ± 1.1 days for candiduria. C. albicans and C. glabrata were isolated in 54.2% and 17% of blood and 66.5% and 21.6% of urine Candida-positive cultures, respectively. Fluconazole was the most frequently prescribed agent. In all candidemic patients, the prescribed curative antifungal agent was active in vitro against the responsible identified strain. Crude ICU mortality was 61.8% for candidemic and 31.3% for candiduric patients. Seventy-five percent of the patients were infected with a unique C. albicans strain; cross-transmission between seven patients was suggested in one hospital.ConclusionsCandidemia is late-onset ICU-acquired infection associated with high mortality. No difference in susceptibility and genetic background were found between blood and urine strains of Candida species.
28 schema:genre article
29 schema:isAccessibleForFree false
30 schema:isPartOf Nc9c7a6594b6c4488a6b1786d43b754a5
31 Nedf651484de14626ac75d8e2dff36849
32 sg:journal.1313639
33 schema:keywords C.
34 Candida species
35 Candida strains
36 Candida-positive cultures
37 DesignA
38 France
39 ICU
40 ICU admission
41 ICU mortality
42 ObjectiveTo
43 PatientsTwo hundred
44 ResultsBlood
45 addition
46 admission
47 adult ICUs
48 agents
49 albicans
50 albicans isolates
51 antifungal agents
52 antifungal susceptibility
53 background
54 blood
55 candidemia
56 candidemic patients
57 candiduria
58 candiduric patients
59 care unit
60 care unit patients
61 concomitant incidence
62 crude ICU mortality
63 culture
64 days
65 differences
66 diversity
67 fluconazole
68 genetic background
69 glabrata
70 high mortality
71 hospital
72 hundreds
73 ill patients
74 incidence
75 infection
76 intensive care unit
77 intensive care unit patients
78 interval
79 isolates
80 management
81 mean incidence
82 mean interval
83 measurements
84 molecular diversity
85 mortality
86 multi-locus sequence types
87 nosocomial candidemia
88 observational study
89 outcomes
90 patients
91 percent
92 prospective observational study
93 same species
94 samples
95 sepsis
96 sequence types
97 signs
98 signs of sepsis
99 species
100 strains
101 study
102 susceptibility
103 types
104 unit patients
105 units
106 urine samples
107 urine strains
108 schema:name Candidemia and candiduria in critically ill patients admitted to intensive care units in France: incidence, molecular diversity, management and outcome
109 schema:pagination 292-299
110 schema:productId N3ddd0b6aac6041ac8f32db4caebe1202
111 N70bedcdcc8ac4fcc97984179dc3f87ed
112 Nb6cfef233ca9442e8931338c083f8ca0
113 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004256795
114 https://doi.org/10.1007/s00134-007-0865-y
115 schema:sdDatePublished 2022-09-02T15:51
116 schema:sdLicense https://scigraph.springernature.com/explorer/license/
117 schema:sdPublisher N16111fdeb1e646d8b9380f0c75000504
118 schema:url https://doi.org/10.1007/s00134-007-0865-y
119 sgo:license sg:explorer/license/
120 sgo:sdDataset articles
121 rdf:type schema:ScholarlyArticle
122 N0efefde1c7d646c5acabd784bfab9ac6 rdf:first sg:person.01276432660.25
123 rdf:rest N3e29a3311d33457ba4c251cd1e938233
124 N16111fdeb1e646d8b9380f0c75000504 schema:name Springer Nature - SN SciGraph project
125 rdf:type schema:Organization
126 N1d2a5674ed8446f48bd55555e9c8a51c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name APACHE
128 rdf:type schema:DefinedTerm
129 N1e7d26ae74914cc5938b1d5ea32b9980 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Critical Illness
131 rdf:type schema:DefinedTerm
132 N1f694f9f9f6a48d5bda276d454628220 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Cross Infection
134 rdf:type schema:DefinedTerm
135 N24166dfc11ab4bba86cbb821a7d74dc9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Humans
137 rdf:type schema:DefinedTerm
138 N26427674c2b443398b63ce413ca20770 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Intensive Care Units
140 rdf:type schema:DefinedTerm
141 N285fee8def15461e9bcf50b4ebdba347 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Incidence
143 rdf:type schema:DefinedTerm
144 N3a0399b67e6341b99ddedea93e14455e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Chi-Square Distribution
146 rdf:type schema:DefinedTerm
147 N3d7266d6ee7f4b369b699e6be9bc3b23 schema:familyName CandiRea Study Group
148 rdf:type schema:Person
149 N3ddd0b6aac6041ac8f32db4caebe1202 schema:name pubmed_id
150 schema:value 17909746
151 rdf:type schema:PropertyValue
152 N3e29a3311d33457ba4c251cd1e938233 rdf:first sg:person.0760564474.73
153 rdf:rest Nbe183061a4dc4e179a0421b4fa07fd2e
154 N4445e5da81bd4194ba08010e6fb90339 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
155 schema:name Aged
156 rdf:type schema:DefinedTerm
157 N66ed0984229a4968b6f042f87e113510 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Prospective Studies
159 rdf:type schema:DefinedTerm
160 N7038efe46ee04ac8b4b78566e0fd2f5b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
161 schema:name Risk Factors
162 rdf:type schema:DefinedTerm
163 N70bedcdcc8ac4fcc97984179dc3f87ed schema:name dimensions_id
164 schema:value pub.1004256795
165 rdf:type schema:PropertyValue
166 N8c87159f01b64a9ca0d2a7cd33b2b988 rdf:first sg:person.01173731273.36
167 rdf:rest Nf66fe21ed27940e5a2526f948d073ecb
168 N8de59619de9149a1b4002942c7d89d45 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
169 schema:name Candida
170 rdf:type schema:DefinedTerm
171 N978cc656a11f44649ff732d6aa9634b6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
172 schema:name Male
173 rdf:type schema:DefinedTerm
174 N99805911655d41a382f7b6563cbcdf87 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
175 schema:name Antifungal Agents
176 rdf:type schema:DefinedTerm
177 Na64f6823f87e4eef890290fa7de28dd4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
178 schema:name Middle Aged
179 rdf:type schema:DefinedTerm
180 Naa2738b53b9a4647ad0f7b662e876a82 rdf:first N3d7266d6ee7f4b369b699e6be9bc3b23
181 rdf:rest rdf:nil
182 Nb6cfef233ca9442e8931338c083f8ca0 schema:name doi
183 schema:value 10.1007/s00134-007-0865-y
184 rdf:type schema:PropertyValue
185 Nb6db50e4ff07471d912297e15a5aac9a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
186 schema:name Outcome Assessment, Health Care
187 rdf:type schema:DefinedTerm
188 Nbe183061a4dc4e179a0421b4fa07fd2e rdf:first sg:person.0645764401.56
189 rdf:rest Naa2738b53b9a4647ad0f7b662e876a82
190 Nc2b69cc0a17f426a87faf7c5d77bff2f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
191 schema:name France
192 rdf:type schema:DefinedTerm
193 Nc9c7a6594b6c4488a6b1786d43b754a5 schema:issueNumber 2
194 rdf:type schema:PublicationIssue
195 Nd3e0be2437c14f938ff31a7116f4c3d3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
196 schema:name Microbial Sensitivity Tests
197 rdf:type schema:DefinedTerm
198 Ndaebf41cb4d64abfbf896d17df821216 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
199 schema:name Female
200 rdf:type schema:DefinedTerm
201 Ne0bac7460eb04cf8acc7c75f1360f314 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
202 schema:name Candidiasis
203 rdf:type schema:DefinedTerm
204 Nedf651484de14626ac75d8e2dff36849 schema:volumeNumber 34
205 rdf:type schema:PublicationVolume
206 Nf66fe21ed27940e5a2526f948d073ecb rdf:first sg:person.0650775470.21
207 rdf:rest N0efefde1c7d646c5acabd784bfab9ac6
208 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
209 schema:name Medical and Health Sciences
210 rdf:type schema:DefinedTerm
211 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
212 schema:name Clinical Sciences
213 rdf:type schema:DefinedTerm
214 sg:journal.1313639 schema:issn 0342-4642
215 1432-1238
216 schema:name Intensive Care Medicine
217 schema:publisher Springer Nature
218 rdf:type schema:Periodical
219 sg:person.01173731273.36 schema:affiliation grid-institutes:grid.508487.6
220 schema:familyName Bougnoux
221 schema:givenName Marie-Elisabeth
222 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01173731273.36
223 rdf:type schema:Person
224 sg:person.01276432660.25 schema:affiliation grid-institutes:grid.413756.2
225 schema:familyName Aegerter
226 schema:givenName Philippe
227 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01276432660.25
228 rdf:type schema:Person
229 sg:person.0645764401.56 schema:affiliation grid-institutes:grid.414093.b
230 schema:familyName Fagon
231 schema:givenName Jean-Yves
232 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0645764401.56
233 rdf:type schema:Person
234 sg:person.0650775470.21 schema:affiliation grid-institutes:grid.414093.b
235 schema:familyName Kac
236 schema:givenName Guillaume
237 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0650775470.21
238 rdf:type schema:Person
239 sg:person.0760564474.73 schema:affiliation grid-institutes:grid.428999.7
240 schema:familyName d’Enfert
241 schema:givenName Christophe
242 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0760564474.73
243 rdf:type schema:Person
244 sg:pub.10.1007/s00134-002-1540-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1046624930
245 https://doi.org/10.1007/s00134-002-1540-y
246 rdf:type schema:CreativeWork
247 sg:pub.10.1007/s00134-003-1807-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1024023872
248 https://doi.org/10.1007/s00134-003-1807-y
249 rdf:type schema:CreativeWork
250 grid-institutes:grid.413756.2 schema:alternateName Informatique Médicale, Hôpital Ambroise-Paré, Boulogne Billancourt, France
251 schema:name Assistance Publique, Hôpitaux de Paris, Paris, France
252 Informatique Médicale, Hôpital Ambroise-Paré, Boulogne Billancourt, France
253 rdf:type schema:Organization
254 grid-institutes:grid.414093.b schema:alternateName Service de Réanimation Médicale, Hôpital Européen Georges Pompidou, Paris, France
255 Unité d’Hygiène Hospitalière, Hôpital Européen Georges Pompidou, Paris, France
256 schema:name Assistance Publique, Hôpitaux de Paris, Paris, France
257 Faculté de Médecine, Université René Descartes, Paris, France
258 Service de Réanimation Médicale, Hôpital Européen Georges Pompidou, Paris, France
259 Unité d’Hygiène Hospitalière, Hôpital Européen Georges Pompidou, Paris, France
260 rdf:type schema:Organization
261 grid-institutes:grid.428999.7 schema:alternateName Unité Biologie et Pathogénicité Fongiques, INRA USC 2019, Institut Pasteur, Paris, France
262 schema:name Unité Biologie et Pathogénicité Fongiques, INRA USC 2019, Institut Pasteur, Paris, France
263 rdf:type schema:Organization
264 grid-institutes:grid.508487.6 schema:alternateName Faculté de Médecine, Université René Descartes, Paris, France
265 schema:name Assistance Publique, Hôpitaux de Paris, Paris, France
266 Faculté de Médecine, Université René Descartes, Paris, France
267 Laboratoire de Parasitologie–Mycologie, Service de Microbiologie, Hôpital Necker Enfants Malades, Paris, France
268 Service de Bactériologie, Virologie, Parasitologie et Hygiène, Hôpital Necker-Enfants Malades, 149, rue de Sèvres, 75473, Paris Cedex 15, France
269 Unité Biologie et Pathogénicité Fongiques, INRA USC 2019, Institut Pasteur, Paris, France
270 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...