Are terminally ill patients dying in the ICU suitable for non-heart beating organ donation? View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2006-03-14

AUTHORS

Jean-Pierre Revelly, Luca Imperatori, Philippe Maravic, Marie-Denise Schaller, René Chioléro

ABSTRACT

ObjectiveTo evaluate the feasibility of implementing a program of controlled non-heart beating organ donation, in patients undergoing the withdrawal of intensive care treatment.Design and settingProspective observational study. Medical and Surgical ICUs in a tertiary university hospital.PatientsConsecutive patients younger than 70 years dying in the ICU after treatment withdrawal for dire neurological prognosis.Measurements and resultsWe analyzed prospectively collected data from the ICU clinical information system. Seventy-three of 516 ICU deaths (13%) were identified, equally distributed among traumatic, stroke, and anoxic brain injury. The management and the course in these three diagnostic categories were similar. All patients underwent withdrawal of mechanical ventilation and half were extubated. Median time to death was of 4.8 h (IQR 1.4–11.5). In 70% of cases the patient received analgesia and 30% sedation. Such treatment was not related to earlier death. Hypotension was observed in 50% of patients during the 30 min preceding cardiac death.ConclusionsWith our current management of terminal patients controlled non-heart beating organ procedure may be difficult due to the duration and variability of the dying process. This observation suggests that we can perform better by evaluating this process moreclosely. More... »

PAGES

708-712

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00134-006-0116-7

DOI

http://dx.doi.org/10.1007/s00134-006-0116-7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1045702086

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/16534569


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