Thrombotic microangiopathy: an atypical cause of acute renal failure in patients with acute pancreatitis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2004-06

AUTHORS

Alexandre Boyer, Karim Chadda, Amar Salah, Guy Bonmarchand

ABSTRACT

OBJECTIVE: To report on the development and treatment of thrombotic microangiopathy, an atypical cause of acute renal failure in patients with acute pancreatitis. DESIGN: Case reports. SETTING: A 21-bed medical intensive care unit at an university hospital. PATIENTS: Two men with acute pancreatitis presented with acute renal failure, neurological manifestations, haemolytic anaemia and thrombocytopenia. Both patients required intensive care. MEASUREMENTS: Fragmented red cell count; levels of haptoglobin, amylase and lipase; serological testing for Escherichia Coli O157; computed tomography of the abdomen. MAIN RESULTS: The patients' courses were rapidly favourable after daily plasma exchange. A review of the existing medical literature was also undertaken. CONCLUSION: As thrombotic microangiopathy may be life-threatening without administration of fresh frozen plasma or plasma exchange, physicians should consider this disease as a possible cause of acute renal failure in patients with acute pancreatitis. More... »

PAGES

1235-1239

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00134-004-2272-y

DOI

http://dx.doi.org/10.1007/s00134-004-2272-y

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1025680016

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15069598


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