The costs of septic syndromes in the intensive care unit and influence of hospital-acquired sepsis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2003-07-10

AUTHORS

Christian Brun-Buisson, Françoise Roudot-Thoraval, Emmanuelle Girou, Catherine Grenier-Sennelier, Isabelle Durand-Zaleski

ABSTRACT

ObjectiveTo document the costs and outcomes of the various forms of the septic syndromes [systemic inflammatory response syndrome (SIRS), sepsis, severe sepsis, septic shock), particularly those associated with infection acquired in an intensive care unit (ICU).DesignProspective data collection for all septic patients admitted to a medical ICU during a 1-year period. Costs were computed from the viewpoint of the hospital.ResultsMean total hospital costs were €26,256, €35,185, and €27,083 for patients with sepsis, severe sepsis, and septic shock, respectively. Total costs varied slightly according to the site of infection and the severity of sepsis but were influenced mostly by its mode of acquisition: patients having sepsis associated with ICU-acquired infection incurred total costs about three times those of patients presenting with infection and sepsis on ICU admission (from €39,908 in patients with ICU acquired sepsis to €44,851 in patients with ICU-acquired septic shock). Stratifying patients by the presence of ICU-acquired infection also showed that a first episode of infection complicated by ICU-acquired sepsis incurred at least 2.5 times more costs than a single episode of sepsis.ConclusionsIn this series the medical costs of sepsis were not markedly influenced by its severity but by its mode of acquisition. Due to wide variations in ICU costs cost-effectiveness analyses of treatments for sepsis should document the case-mix of patients and the contribution to this of nosocomial infections. More... »

PAGES

1464-1471

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00134-003-1877-x

DOI

http://dx.doi.org/10.1007/s00134-003-1877-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1020228011

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/12856120


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