Is the ADA/EASD algorithm for the management of type 2 diabetes (January 2009) based on evidence or opinion? A critical ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2010-07

AUTHORS

G. Schernthaner, A. H. Barnett, D. J. Betteridge, R. Carmena, A. Ceriello, B. Charbonnel, M. Hanefeld, R. Lehmann, M. T. Malecki, R. Nesto, V. Pirags, A. Scheen, J. Seufert, A. Sjohölm, A. Tsatsoulis, R. DeFronzo

ABSTRACT

The ADA and the EASD recently published a consensus statement for the medical management of hyperglycaemia in patients with type 2 diabetes. The authors advocate initial treatment with metformin monotherapy and lifestyle modification, followed by addition of basal insulin or a sulfonylurea if glycaemic goals are not met (tier 1 recommendations). All other glucose-lowering therapies are relegated to a secondary (tier 2) status and only recommended for selected clinical settings. In our view, this algorithm does not offer physicians and patients the appropriate selection of options to individualise and optimise care with a view to sustained control of blood glucose and reduction both of diabetes complications and cardiovascular risk. This paper critically assesses the basis of the ADA/EASD algorithm and the resulting tiers of treatment options. More... »

PAGES

1258-1269

References to SciGraph publications

  • 2008-06. Use of Insulin to Improve Glycemic Control in Diabetes Mellitus in CARDIOVASCULAR DRUGS AND THERAPY
  • 2009-10. Optimal insulin regimens in type 2 diabetes mellitus: systematic review and meta-analyses in DIABETOLOGIA
  • 2006-08. Management of hyperglycaemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy in DIABETOLOGIA
  • 2008-06. Metformin: Effects on Micro and Macrovascular Complications in Type 2 Diabetes in CARDIOVASCULAR DRUGS AND THERAPY
  • 2006-09. Vildagliptin therapy reduces postprandial intestinal triglyceride-rich lipoprotein particles in patients with type 2 diabetes in DIABETOLOGIA
  • 2008-03. A randomised, 52-week, treat-to-target trial comparing insulin detemir with insulin glargine when administered as add-on to glucose-lowering drugs in insulin-naive people with type 2 diabetes in DIABETOLOGIA
  • 2009-03. Important differences: Canadian Diabetes Association 2008 clinical practice guidelines and the consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes in DIABETOLOGIA
  • 2006-05. Risk of mortality and adverse cardiovascular outcomes in type 2 diabetes: a comparison of patients treated with sulfonylureas and metformin in DIABETOLOGIA
  • 2009-12. Actos Now for the prevention of diabetes (ACT NOW) study in BMC ENDOCRINE DISORDERS
  • 2006-12. Improving the use of research evidence in guideline development: 1. Guidelines for guidelines in HEALTH RESEARCH POLICY AND SYSTEMS
  • 2009-01. Medical management of hyperglycaemia in type 2 diabetes mellitus: a consensus algorithm for the initiation and adjustment of therapy in DIABETOLOGIA
  • 2009-09. The influence of glucose-lowering therapies on cancer risk in type 2 diabetes in DIABETOLOGIA
  • 2008-12. Development of evidence-based clinical practice guidelines (CPGs): comparing approaches in IMPLEMENTATION SCIENCE
  • 2009-07. Risk of Fractures with Glitazones in DRUG SAFETY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00125-010-1702-3

    DOI

    http://dx.doi.org/10.1007/s00125-010-1702-3

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1015794130

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/20352408


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Clinical Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Algorithms", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Cardiovascular Diseases", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Diabetes Mellitus, Type 2", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Europe", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Hyperglycemia", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Hypoglycemic Agents", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Risk Factors", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Societies, Medical", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "United States", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Krankenanstalt Rudolfstiftung der Stadt Wien", 
              "id": "https://www.grid.ac/institutes/grid.413303.6", 
              "name": [
                "Department of Medicine I, Rudolfstiftung Hospital-Vienna, Juchgasse 25, 1030, Vienna, Austria"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Schernthaner", 
            "givenName": "G.", 
            "id": "sg:person.0763256671.40", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0763256671.40"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Birmingham", 
              "id": "https://www.grid.ac/institutes/grid.6572.6", 
              "name": [
                "University of Birmingham and Heart of England NHS Trust, Birmingham, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Barnett", 
            "givenName": "A. H.", 
            "id": "sg:person.015330067542.66", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015330067542.66"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University College Hospital", 
              "id": "https://www.grid.ac/institutes/grid.439749.4", 
              "name": [
                "University College London Hospitals, London, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Betteridge", 
            "givenName": "D. J.", 
            "id": "sg:person.01353641575.01", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01353641575.01"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Valencia", 
              "id": "https://www.grid.ac/institutes/grid.5338.d", 
              "name": [
                "University of Valencia, Valencia, Spain"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Carmena", 
            "givenName": "R.", 
            "id": "sg:person.01031370311.36", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01031370311.36"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Udine", 
              "id": "https://www.grid.ac/institutes/grid.5390.f", 
              "name": [
                "Department of Endocrinology, University of Udine, Udine, Italy"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ceriello", 
            "givenName": "A.", 
            "id": "sg:person.0711436716.35", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0711436716.35"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Centre Hospitalier Universitaire de Nantes", 
              "id": "https://www.grid.ac/institutes/grid.277151.7", 
              "name": [
                "University Hospital, Nantes, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Charbonnel", 
            "givenName": "B.", 
            "id": "sg:person.01004713466.50", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01004713466.50"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Center for Clinical Studies, GWT Dresden, Dresden, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hanefeld", 
            "givenName": "M.", 
            "id": "sg:person.01256767110.97", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01256767110.97"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital of Zurich", 
              "id": "https://www.grid.ac/institutes/grid.412004.3", 
              "name": [
                "University Hospital Zurich, Zurich, Switzerland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lehmann", 
            "givenName": "R.", 
            "id": "sg:person.01023744203.45", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023744203.45"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Jagiellonian University", 
              "id": "https://www.grid.ac/institutes/grid.5522.0", 
              "name": [
                "Jagiellonian University, Krakow, Poland"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Malecki", 
            "givenName": "M. T.", 
            "id": "sg:person.01141511307.00", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01141511307.00"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Lahey Hospital and Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.415731.5", 
              "name": [
                "Lahey Clinic Medical Center, Burlington, MA, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Nesto", 
            "givenName": "R.", 
            "id": "sg:person.01103235425.05", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01103235425.05"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Latvia", 
              "id": "https://www.grid.ac/institutes/grid.9845.0", 
              "name": [
                "University of Latvia, Riga, Latvia"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Pirags", 
            "givenName": "V.", 
            "id": "sg:person.01110113007.58", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01110113007.58"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "CHU Sart Tilman, University of Li\u00e8ge, Li\u00e8ge, Belgium"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Scheen", 
            "givenName": "A.", 
            "id": "sg:person.014716227772.55", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014716227772.55"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Medical Center Freiburg", 
              "id": "https://www.grid.ac/institutes/grid.7708.8", 
              "name": [
                "University Hospital of Freiburg, Freiburg, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Seufert", 
            "givenName": "J.", 
            "id": "sg:person.0773023275.40", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0773023275.40"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Karolinska Institute", 
              "id": "https://www.grid.ac/institutes/grid.4714.6", 
              "name": [
                "Karolinska Institutet, Stockholm, Sweden"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Sjoh\u00f6lm", 
            "givenName": "A.", 
            "id": "sg:person.01225563141.81", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01225563141.81"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Ioannina", 
              "id": "https://www.grid.ac/institutes/grid.9594.1", 
              "name": [
                "University of Ioannina, Ioannina, Greece"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Tsatsoulis", 
            "givenName": "A.", 
            "id": "sg:person.01341526404.94", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341526404.94"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "The University of Texas Health Science Center at San Antonio", 
              "id": "https://www.grid.ac/institutes/grid.267309.9", 
              "name": [
                "University of Texas Health Science Center, San Antonio, TX, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "DeFronzo", 
            "givenName": "R.", 
            "id": "sg:person.01306763341.60", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01306763341.60"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1016/j.amjcard.2007.05.038", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000500727"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1056/nejmoa0802987", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000508710"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/pds.1470", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000564806"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(09)60953-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001688725"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2337/dc09-s013", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001845211"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2337/diacare.29.03.06.dc05-0695", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002161808"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/jama.299.13.1561", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002198164"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1478-4505-4-13", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002545304", 
              "https://doi.org/10.1186/1478-4505-4-13"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10557-008-6092-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003295968", 
              "https://doi.org/10.1007/s10557-008-6092-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10557-008-6092-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003295968", 
              "https://doi.org/10.1007/s10557-008-6092-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10557-008-6092-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003295968", 
              "https://doi.org/10.1007/s10557-008-6092-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00125-009-1468-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003702735", 
              "https://doi.org/10.1007/s00125-009-1468-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00125-009-1468-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003702735", 
              "https://doi.org/10.1007/s00125-009-1468-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00125-009-1468-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003702735", 
              "https://doi.org/10.1007/s00125-009-1468-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00125-009-1468-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003702735", 
              "https://doi.org/10.1007/s00125-009-1468-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1056/nejm199309303291401", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004144761"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2337/db09-9028", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004893088"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1517/14740330802432003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005069211"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10557-008-6101-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006309510", 
              "https://doi.org/10.1007/s10557-008-6101-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10557-008-6101-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006309510", 
              "https://doi.org/10.1007/s10557-008-6101-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10557-008-6101-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006309510", 
              "https://doi.org/10.1007/s10557-008-6101-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.diabres.2008.02.011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006704575"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1185/03007990902820519", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007161043"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1748-5908-3-45", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008514248", 
              "https://doi.org/10.1186/1748-5908-3-45"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2337/diacare.28.2.260", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009165501"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1742-1241.2008.01941.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009611725"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2337/dc06-0564", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010337082"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00125-006-0316-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010455491", 
              "https://doi.org/10.1007/s00125-006-0316-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00125-006-0316-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010455491", 
              "https://doi.org/10.1007/s00125-006-0316-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00125-006-0316-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010455491", 
              "https://doi.org/10.1007/s00125-006-0316-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2337/dc08-9017", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010475808"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1056/nejmoa072761", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010634292"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(08)60762-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011950373"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00125-006-0340-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012299813", 
              "https://doi.org/10.1007/s00125-006-0340-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00125-006-0340-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012299813", 
              "https://doi.org/10.1007/s00125-006-0340-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00125-006-0340-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012299813", 
              "https://doi.org/10.1007/s00125-006-0340-2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jacc.2008.11.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012372299"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1185/030079908x253870", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012403641"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/archinte.164.19.2097", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012574378"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(98)07037-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015697368"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/jama.298.10.1180", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016607544"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/bmj.328.7454.1490", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017237059"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(09)61969-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017470643"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00125-008-1157-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018087341", 
              "https://doi.org/10.1007/s00125-008-1157-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00125-008-1157-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018087341", 
              "https://doi.org/10.1007/s00125-008-1157-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00125-008-1157-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018087341", 
              "https://doi.org/10.1007/s00125-008-1157-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2337/dc08-1671", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018104950"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.beem.2009.03.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018422376"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/jama.298.10.1189", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018539400"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1462-8902.2004.00325.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018829513"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(98)07019-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018881858"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0735-1097(98)00557-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019396106"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2337/db08-1193", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019574560"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.clinthera.2008.11.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020313983"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1056/nejmoa066224", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021101828"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.diabres.2008.04.007", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021927937"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1056/nejmoa0802743", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022234833"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2337/dc08-0167", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022873493"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1464-5491.2004.01426.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024001006"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1464-5491.2004.01426.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024001006"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.2165/00002018-200932070-00001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024470694", 
              "https://doi.org/10.2165/00002018-200932070-00001"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.2165/00002018-200932070-00001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024470694", 
              "https://doi.org/10.2165/00002018-200932070-00001"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(06)69420-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025966136"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.clinthera.2007.11.016", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027653512"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00125-006-0176-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027817456", 
              "https://doi.org/10.1007/s00125-006-0176-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00125-006-0176-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027817456", 
              "https://doi.org/10.1007/s00125-006-0176-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00125-006-0176-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027817456", 
              "https://doi.org/10.1007/s00125-006-0176-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2337/dc08-2175", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028017606"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1742-1241.2009.02025.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028098423"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1742-1241.2009.02025.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028098423"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1053/j.gastro.2009.04.013", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028783747"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(05)67528-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029983783"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jacc.2008.10.033", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030642738"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/pds.1630", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031856409"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1161/circheartfailure.108.810887", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033832697"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1161/circheartfailure.108.810887", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033832697"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1463-1326.2006.00704.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033967254"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1464-5491.2004.01416.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034102530"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1056/nejmoa0806470", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034293538"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00125-007-0911-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034961770", 
              "https://doi.org/10.1007/s00125-007-0911-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00125-007-0911-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034961770", 
              "https://doi.org/10.1007/s00125-007-0911-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00125-007-0911-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034961770", 
              "https://doi.org/10.1007/s00125-007-0911-x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2337/dc08-s001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035034566"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/eurheartj/ehm529", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035809392"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1056/nejmoa0905479", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036067726"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1463-1326.2008.00994.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036104286"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/eurheartj/ehm124", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036766229"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.clinthera.2007.07.003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037270625"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/eurheartj/ehm518", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038852216"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/bmj.39314.620174.80", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040535374"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00125-009-1440-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041996770", 
              "https://doi.org/10.1007/s00125-009-1440-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00125-009-1440-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041996770", 
              "https://doi.org/10.1007/s00125-009-1440-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00125-009-1440-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041996770", 
              "https://doi.org/10.1007/s00125-009-1440-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00125-009-1440-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041996770", 
              "https://doi.org/10.1007/s00125-009-1440-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1463-1326.2008.00892.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043304788"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0168-8227(95)01064-k", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043400052"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1056/nejmoa052187", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045615611"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1472-6823-9-17", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045668457", 
              "https://doi.org/10.1186/1472-6823-9-17"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/eurheartj/ehm519", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045765423"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/bmj.b4731", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045927678"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/eurheartj/ehi199", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046635001"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2337/diacare.25.12.2244", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047089706"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/jama.296.21.joc60158", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047355148"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2337/dc08-1797", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048284872"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1161/01.cir.99.20.2626", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048782795"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/eurheartj/ehl260", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050871132"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/eurheartj/ehn114", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051704138"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1463-1326.2007.00715.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052644745"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(08)60485-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052882493"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2337/dc08-0075", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053378796"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/jama.298.2.194", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053622743"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/pds.1598", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053652377"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00125-008-1236-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053708663", 
              "https://doi.org/10.1007/s00125-008-1236-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00125-008-1236-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053708663", 
              "https://doi.org/10.1007/s00125-008-1236-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00125-008-1236-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053708663", 
              "https://doi.org/10.1007/s00125-008-1236-0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1055/s-0029-1239559", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1057205939"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1055/s-2006-949655", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1057466018"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1185/030079907x253870", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064132407"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/10.1210/er.2006-0038", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064237786"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2003-030861", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064287042"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jcem.86.1.7157", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064323832"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jcem.87.6.8567", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064325294"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2147/vhrm.s1707", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1069102977"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2337/diacare.17.10.1100", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1070746175"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.7326/0003-4819-147-6-200709180-00178", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1073709506"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.7326/0003-4819-147-8-200710160-00182", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1073709554"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1074671290", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1077526034", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1077728361", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1080690013", 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2010-07", 
        "datePublishedReg": "2010-07-01", 
        "description": "The ADA and the EASD recently published a consensus statement for the medical management of hyperglycaemia in patients with type 2 diabetes. The authors advocate initial treatment with metformin monotherapy and lifestyle modification, followed by addition of basal insulin or a sulfonylurea if glycaemic goals are not met (tier 1 recommendations). All other glucose-lowering therapies are relegated to a secondary (tier 2) status and only recommended for selected clinical settings. In our view, this algorithm does not offer physicians and patients the appropriate selection of options to individualise and optimise care with a view to sustained control of blood glucose and reduction both of diabetes complications and cardiovascular risk. This paper critically assesses the basis of the ADA/EASD algorithm and the resulting tiers of treatment options.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1007/s00125-010-1702-3", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": true, 
        "isPartOf": [
          {
            "id": "sg:journal.1001482", 
            "issn": [
              "0012-186X", 
              "1432-0428"
            ], 
            "name": "Diabetologia", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "7", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "53"
          }
        ], 
        "name": "Is the ADA/EASD algorithm for the management of type 2 diabetes (January 2009) based on evidence or opinion? A critical analysis", 
        "pagination": "1258-1269", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "4b4169322d8e1a1e845d7cbe1190e96295d0f401683f2069e2783b31e41c4f7f"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "20352408"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "0006777"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/s00125-010-1702-3"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1015794130"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/s00125-010-1702-3", 
          "https://app.dimensions.ai/details/publication/pub.1015794130"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-11T10:19", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000348_0000000348/records_54322_00000000.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://link.springer.com/10.1007%2Fs00125-010-1702-3"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00125-010-1702-3'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00125-010-1702-3'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00125-010-1702-3'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00125-010-1702-3'


     

    This table displays all metadata directly associated to this object as RDF triples.

    579 TRIPLES      21 PREDICATES      143 URIs      31 LITERALS      19 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/s00125-010-1702-3 schema:about N0fc045f6542b4251988e35114c72e5ff
    2 N2af554aeb6a445cf8d5e8ecb1c8d6935
    3 N3108cea6c19d428da0104944ef7b17b6
    4 N3155c4a9cea94e8fac6aa7b1f2bc7181
    5 N34e6c1e69bc545da908231888dff3ea8
    6 N90b7070e59be4a9c8e55fd730c113688
    7 N9ce34b09bd494cf6bab62cf0649351a6
    8 Na17027ee0877440eb409ec3dfd403f1f
    9 Nc1777aed3c8441239b9ae63e9cf4408a
    10 Nd31e6a516d3f45eda929d6237793ea05
    11 anzsrc-for:11
    12 anzsrc-for:1103
    13 schema:author Nb1abfe51e6394bb198713b16e65b4cf8
    14 schema:citation sg:pub.10.1007/s00125-006-0176-9
    15 sg:pub.10.1007/s00125-006-0316-2
    16 sg:pub.10.1007/s00125-006-0340-2
    17 sg:pub.10.1007/s00125-007-0911-x
    18 sg:pub.10.1007/s00125-008-1157-y
    19 sg:pub.10.1007/s00125-008-1236-0
    20 sg:pub.10.1007/s00125-009-1440-6
    21 sg:pub.10.1007/s00125-009-1468-7
    22 sg:pub.10.1007/s10557-008-6092-0
    23 sg:pub.10.1007/s10557-008-6101-3
    24 sg:pub.10.1186/1472-6823-9-17
    25 sg:pub.10.1186/1478-4505-4-13
    26 sg:pub.10.1186/1748-5908-3-45
    27 sg:pub.10.2165/00002018-200932070-00001
    28 https://app.dimensions.ai/details/publication/pub.1074671290
    29 https://app.dimensions.ai/details/publication/pub.1077526034
    30 https://app.dimensions.ai/details/publication/pub.1077728361
    31 https://app.dimensions.ai/details/publication/pub.1080690013
    32 https://doi.org/10.1001/archinte.164.19.2097
    33 https://doi.org/10.1001/jama.296.21.joc60158
    34 https://doi.org/10.1001/jama.298.10.1180
    35 https://doi.org/10.1001/jama.298.10.1189
    36 https://doi.org/10.1001/jama.298.2.194
    37 https://doi.org/10.1001/jama.299.13.1561
    38 https://doi.org/10.1002/pds.1470
    39 https://doi.org/10.1002/pds.1598
    40 https://doi.org/10.1002/pds.1630
    41 https://doi.org/10.1016/0168-8227(95)01064-k
    42 https://doi.org/10.1016/j.amjcard.2007.05.038
    43 https://doi.org/10.1016/j.beem.2009.03.008
    44 https://doi.org/10.1016/j.clinthera.2007.07.003
    45 https://doi.org/10.1016/j.clinthera.2007.11.016
    46 https://doi.org/10.1016/j.clinthera.2008.11.001
    47 https://doi.org/10.1016/j.diabres.2008.02.011
    48 https://doi.org/10.1016/j.diabres.2008.04.007
    49 https://doi.org/10.1016/j.jacc.2008.10.033
    50 https://doi.org/10.1016/j.jacc.2008.11.008
    51 https://doi.org/10.1016/s0140-6736(05)67528-9
    52 https://doi.org/10.1016/s0140-6736(06)69420-8
    53 https://doi.org/10.1016/s0140-6736(08)60485-7
    54 https://doi.org/10.1016/s0140-6736(08)60762-x
    55 https://doi.org/10.1016/s0140-6736(09)60953-3
    56 https://doi.org/10.1016/s0140-6736(09)61969-3
    57 https://doi.org/10.1016/s0140-6736(98)07019-6
    58 https://doi.org/10.1016/s0140-6736(98)07037-8
    59 https://doi.org/10.1016/s0735-1097(98)00557-9
    60 https://doi.org/10.1053/j.gastro.2009.04.013
    61 https://doi.org/10.1055/s-0029-1239559
    62 https://doi.org/10.1055/s-2006-949655
    63 https://doi.org/10.1056/nejm199309303291401
    64 https://doi.org/10.1056/nejmoa052187
    65 https://doi.org/10.1056/nejmoa066224
    66 https://doi.org/10.1056/nejmoa072761
    67 https://doi.org/10.1056/nejmoa0802743
    68 https://doi.org/10.1056/nejmoa0802987
    69 https://doi.org/10.1056/nejmoa0806470
    70 https://doi.org/10.1056/nejmoa0905479
    71 https://doi.org/10.1093/eurheartj/ehi199
    72 https://doi.org/10.1093/eurheartj/ehl260
    73 https://doi.org/10.1093/eurheartj/ehm124
    74 https://doi.org/10.1093/eurheartj/ehm518
    75 https://doi.org/10.1093/eurheartj/ehm519
    76 https://doi.org/10.1093/eurheartj/ehm529
    77 https://doi.org/10.1093/eurheartj/ehn114
    78 https://doi.org/10.1111/j.1462-8902.2004.00325.x
    79 https://doi.org/10.1111/j.1463-1326.2006.00704.x
    80 https://doi.org/10.1111/j.1463-1326.2007.00715.x
    81 https://doi.org/10.1111/j.1463-1326.2008.00892.x
    82 https://doi.org/10.1111/j.1463-1326.2008.00994.x
    83 https://doi.org/10.1111/j.1464-5491.2004.01416.x
    84 https://doi.org/10.1111/j.1464-5491.2004.01426.x
    85 https://doi.org/10.1111/j.1742-1241.2008.01941.x
    86 https://doi.org/10.1111/j.1742-1241.2009.02025.x
    87 https://doi.org/10.1136/bmj.328.7454.1490
    88 https://doi.org/10.1136/bmj.39314.620174.80
    89 https://doi.org/10.1136/bmj.b4731
    90 https://doi.org/10.1161/01.cir.99.20.2626
    91 https://doi.org/10.1161/circheartfailure.108.810887
    92 https://doi.org/10.1185/030079907x253870
    93 https://doi.org/10.1185/030079908x253870
    94 https://doi.org/10.1185/03007990902820519
    95 https://doi.org/10.1210/10.1210/er.2006-0038
    96 https://doi.org/10.1210/jc.2003-030861
    97 https://doi.org/10.1210/jcem.86.1.7157
    98 https://doi.org/10.1210/jcem.87.6.8567
    99 https://doi.org/10.1517/14740330802432003
    100 https://doi.org/10.2147/vhrm.s1707
    101 https://doi.org/10.2337/db08-1193
    102 https://doi.org/10.2337/db09-9028
    103 https://doi.org/10.2337/dc06-0564
    104 https://doi.org/10.2337/dc08-0075
    105 https://doi.org/10.2337/dc08-0167
    106 https://doi.org/10.2337/dc08-1671
    107 https://doi.org/10.2337/dc08-1797
    108 https://doi.org/10.2337/dc08-2175
    109 https://doi.org/10.2337/dc08-9017
    110 https://doi.org/10.2337/dc08-s001
    111 https://doi.org/10.2337/dc09-s013
    112 https://doi.org/10.2337/diacare.17.10.1100
    113 https://doi.org/10.2337/diacare.25.12.2244
    114 https://doi.org/10.2337/diacare.28.2.260
    115 https://doi.org/10.2337/diacare.29.03.06.dc05-0695
    116 https://doi.org/10.7326/0003-4819-147-6-200709180-00178
    117 https://doi.org/10.7326/0003-4819-147-8-200710160-00182
    118 schema:datePublished 2010-07
    119 schema:datePublishedReg 2010-07-01
    120 schema:description The ADA and the EASD recently published a consensus statement for the medical management of hyperglycaemia in patients with type 2 diabetes. The authors advocate initial treatment with metformin monotherapy and lifestyle modification, followed by addition of basal insulin or a sulfonylurea if glycaemic goals are not met (tier 1 recommendations). All other glucose-lowering therapies are relegated to a secondary (tier 2) status and only recommended for selected clinical settings. In our view, this algorithm does not offer physicians and patients the appropriate selection of options to individualise and optimise care with a view to sustained control of blood glucose and reduction both of diabetes complications and cardiovascular risk. This paper critically assesses the basis of the ADA/EASD algorithm and the resulting tiers of treatment options.
    121 schema:genre research_article
    122 schema:inLanguage en
    123 schema:isAccessibleForFree true
    124 schema:isPartOf N2f69f0eb9774457fa8f9f62c3b34f377
    125 N8a814caa4d064c7791da0373e8e5cb2e
    126 sg:journal.1001482
    127 schema:name Is the ADA/EASD algorithm for the management of type 2 diabetes (January 2009) based on evidence or opinion? A critical analysis
    128 schema:pagination 1258-1269
    129 schema:productId N0472a40664eb48ad9d4027b48ca3142c
    130 N0921113cea0345639ec560315d5ce140
    131 N87485ebbdccf471b8095b9f3469807d4
    132 Nbb03938723854a5795b18776399ef7df
    133 Nbfff777549f44a8599304bd0119b5619
    134 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015794130
    135 https://doi.org/10.1007/s00125-010-1702-3
    136 schema:sdDatePublished 2019-04-11T10:19
    137 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    138 schema:sdPublisher Na32bd9c4b9f941489bd3d1d09d330141
    139 schema:url https://link.springer.com/10.1007%2Fs00125-010-1702-3
    140 sgo:license sg:explorer/license/
    141 sgo:sdDataset articles
    142 rdf:type schema:ScholarlyArticle
    143 N0472a40664eb48ad9d4027b48ca3142c schema:name pubmed_id
    144 schema:value 20352408
    145 rdf:type schema:PropertyValue
    146 N0921113cea0345639ec560315d5ce140 schema:name readcube_id
    147 schema:value 4b4169322d8e1a1e845d7cbe1190e96295d0f401683f2069e2783b31e41c4f7f
    148 rdf:type schema:PropertyValue
    149 N0a3e60e7c8e8430db981eda250073671 rdf:first sg:person.01031370311.36
    150 rdf:rest Na02e12479e1f4c5e942cb97705197994
    151 N0e5d36bb5100477da857bfb64e6ff3b3 rdf:first sg:person.01103235425.05
    152 rdf:rest N95cbed5c74c7415f96d6756aad4d31ca
    153 N0fc045f6542b4251988e35114c72e5ff schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    154 schema:name Risk Factors
    155 rdf:type schema:DefinedTerm
    156 N1632b92960bd4554a3f2f0f425637508 schema:name CHU Sart Tilman, University of Liège, Liège, Belgium
    157 rdf:type schema:Organization
    158 N2a8a89fccbab4aeaaaf5ddc7eb35c5f7 rdf:first sg:person.01225563141.81
    159 rdf:rest N8aecbb90355440a295e8dd09c63f7e56
    160 N2af554aeb6a445cf8d5e8ecb1c8d6935 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    161 schema:name Hypoglycemic Agents
    162 rdf:type schema:DefinedTerm
    163 N2f69f0eb9774457fa8f9f62c3b34f377 schema:volumeNumber 53
    164 rdf:type schema:PublicationVolume
    165 N3108cea6c19d428da0104944ef7b17b6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    166 schema:name Humans
    167 rdf:type schema:DefinedTerm
    168 N3155c4a9cea94e8fac6aa7b1f2bc7181 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    169 schema:name Cardiovascular Diseases
    170 rdf:type schema:DefinedTerm
    171 N34e6c1e69bc545da908231888dff3ea8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    172 schema:name United States
    173 rdf:type schema:DefinedTerm
    174 N3b9f3a8557f643749844888230ed14cb rdf:first sg:person.015330067542.66
    175 rdf:rest Na35bf252ccba44c4a0d456776678b040
    176 N3d13dd68946842feaa630d3cb3d43fb3 rdf:first sg:person.01256767110.97
    177 rdf:rest N6d2a4709a61e4adf9583ca60d94d87cc
    178 N6d2a4709a61e4adf9583ca60d94d87cc rdf:first sg:person.01023744203.45
    179 rdf:rest Nf2cb7b98c6904b16a8a131dbb5edf1c5
    180 N7adda7ebdb11428f990654c7833370ea rdf:first sg:person.01306763341.60
    181 rdf:rest rdf:nil
    182 N87485ebbdccf471b8095b9f3469807d4 schema:name doi
    183 schema:value 10.1007/s00125-010-1702-3
    184 rdf:type schema:PropertyValue
    185 N8a814caa4d064c7791da0373e8e5cb2e schema:issueNumber 7
    186 rdf:type schema:PublicationIssue
    187 N8aecbb90355440a295e8dd09c63f7e56 rdf:first sg:person.01341526404.94
    188 rdf:rest N7adda7ebdb11428f990654c7833370ea
    189 N90b7070e59be4a9c8e55fd730c113688 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    190 schema:name Europe
    191 rdf:type schema:DefinedTerm
    192 N913bade0dc5d4fc38cdbedc1a9c17be7 rdf:first sg:person.014716227772.55
    193 rdf:rest Nb9c3a9a726134ec78676eb95dd8e96b5
    194 N95cbed5c74c7415f96d6756aad4d31ca rdf:first sg:person.01110113007.58
    195 rdf:rest N913bade0dc5d4fc38cdbedc1a9c17be7
    196 N9bbd288450ed484395fe41ff54e82970 rdf:first sg:person.01004713466.50
    197 rdf:rest N3d13dd68946842feaa630d3cb3d43fb3
    198 N9ce34b09bd494cf6bab62cf0649351a6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    199 schema:name Societies, Medical
    200 rdf:type schema:DefinedTerm
    201 Na02e12479e1f4c5e942cb97705197994 rdf:first sg:person.0711436716.35
    202 rdf:rest N9bbd288450ed484395fe41ff54e82970
    203 Na17027ee0877440eb409ec3dfd403f1f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    204 schema:name Algorithms
    205 rdf:type schema:DefinedTerm
    206 Na32bd9c4b9f941489bd3d1d09d330141 schema:name Springer Nature - SN SciGraph project
    207 rdf:type schema:Organization
    208 Na35bf252ccba44c4a0d456776678b040 rdf:first sg:person.01353641575.01
    209 rdf:rest N0a3e60e7c8e8430db981eda250073671
    210 Nb1abfe51e6394bb198713b16e65b4cf8 rdf:first sg:person.0763256671.40
    211 rdf:rest N3b9f3a8557f643749844888230ed14cb
    212 Nb9c3a9a726134ec78676eb95dd8e96b5 rdf:first sg:person.0773023275.40
    213 rdf:rest N2a8a89fccbab4aeaaaf5ddc7eb35c5f7
    214 Nbb03938723854a5795b18776399ef7df schema:name dimensions_id
    215 schema:value pub.1015794130
    216 rdf:type schema:PropertyValue
    217 Nbeed936d2b5049d4894921829dd169c0 schema:name Center for Clinical Studies, GWT Dresden, Dresden, Germany
    218 rdf:type schema:Organization
    219 Nbfff777549f44a8599304bd0119b5619 schema:name nlm_unique_id
    220 schema:value 0006777
    221 rdf:type schema:PropertyValue
    222 Nc1777aed3c8441239b9ae63e9cf4408a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    223 schema:name Diabetes Mellitus, Type 2
    224 rdf:type schema:DefinedTerm
    225 Nd31e6a516d3f45eda929d6237793ea05 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    226 schema:name Hyperglycemia
    227 rdf:type schema:DefinedTerm
    228 Nf2cb7b98c6904b16a8a131dbb5edf1c5 rdf:first sg:person.01141511307.00
    229 rdf:rest N0e5d36bb5100477da857bfb64e6ff3b3
    230 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    231 schema:name Medical and Health Sciences
    232 rdf:type schema:DefinedTerm
    233 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
    234 schema:name Clinical Sciences
    235 rdf:type schema:DefinedTerm
    236 sg:journal.1001482 schema:issn 0012-186X
    237 1432-0428
    238 schema:name Diabetologia
    239 rdf:type schema:Periodical
    240 sg:person.01004713466.50 schema:affiliation https://www.grid.ac/institutes/grid.277151.7
    241 schema:familyName Charbonnel
    242 schema:givenName B.
    243 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01004713466.50
    244 rdf:type schema:Person
    245 sg:person.01023744203.45 schema:affiliation https://www.grid.ac/institutes/grid.412004.3
    246 schema:familyName Lehmann
    247 schema:givenName R.
    248 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023744203.45
    249 rdf:type schema:Person
    250 sg:person.01031370311.36 schema:affiliation https://www.grid.ac/institutes/grid.5338.d
    251 schema:familyName Carmena
    252 schema:givenName R.
    253 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01031370311.36
    254 rdf:type schema:Person
    255 sg:person.01103235425.05 schema:affiliation https://www.grid.ac/institutes/grid.415731.5
    256 schema:familyName Nesto
    257 schema:givenName R.
    258 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01103235425.05
    259 rdf:type schema:Person
    260 sg:person.01110113007.58 schema:affiliation https://www.grid.ac/institutes/grid.9845.0
    261 schema:familyName Pirags
    262 schema:givenName V.
    263 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01110113007.58
    264 rdf:type schema:Person
    265 sg:person.01141511307.00 schema:affiliation https://www.grid.ac/institutes/grid.5522.0
    266 schema:familyName Malecki
    267 schema:givenName M. T.
    268 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01141511307.00
    269 rdf:type schema:Person
    270 sg:person.01225563141.81 schema:affiliation https://www.grid.ac/institutes/grid.4714.6
    271 schema:familyName Sjohölm
    272 schema:givenName A.
    273 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01225563141.81
    274 rdf:type schema:Person
    275 sg:person.01256767110.97 schema:affiliation Nbeed936d2b5049d4894921829dd169c0
    276 schema:familyName Hanefeld
    277 schema:givenName M.
    278 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01256767110.97
    279 rdf:type schema:Person
    280 sg:person.01306763341.60 schema:affiliation https://www.grid.ac/institutes/grid.267309.9
    281 schema:familyName DeFronzo
    282 schema:givenName R.
    283 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01306763341.60
    284 rdf:type schema:Person
    285 sg:person.01341526404.94 schema:affiliation https://www.grid.ac/institutes/grid.9594.1
    286 schema:familyName Tsatsoulis
    287 schema:givenName A.
    288 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341526404.94
    289 rdf:type schema:Person
    290 sg:person.01353641575.01 schema:affiliation https://www.grid.ac/institutes/grid.439749.4
    291 schema:familyName Betteridge
    292 schema:givenName D. J.
    293 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01353641575.01
    294 rdf:type schema:Person
    295 sg:person.014716227772.55 schema:affiliation N1632b92960bd4554a3f2f0f425637508
    296 schema:familyName Scheen
    297 schema:givenName A.
    298 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014716227772.55
    299 rdf:type schema:Person
    300 sg:person.015330067542.66 schema:affiliation https://www.grid.ac/institutes/grid.6572.6
    301 schema:familyName Barnett
    302 schema:givenName A. H.
    303 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015330067542.66
    304 rdf:type schema:Person
    305 sg:person.0711436716.35 schema:affiliation https://www.grid.ac/institutes/grid.5390.f
    306 schema:familyName Ceriello
    307 schema:givenName A.
    308 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0711436716.35
    309 rdf:type schema:Person
    310 sg:person.0763256671.40 schema:affiliation https://www.grid.ac/institutes/grid.413303.6
    311 schema:familyName Schernthaner
    312 schema:givenName G.
    313 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0763256671.40
    314 rdf:type schema:Person
    315 sg:person.0773023275.40 schema:affiliation https://www.grid.ac/institutes/grid.7708.8
    316 schema:familyName Seufert
    317 schema:givenName J.
    318 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0773023275.40
    319 rdf:type schema:Person
    320 sg:pub.10.1007/s00125-006-0176-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027817456
    321 https://doi.org/10.1007/s00125-006-0176-9
    322 rdf:type schema:CreativeWork
    323 sg:pub.10.1007/s00125-006-0316-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010455491
    324 https://doi.org/10.1007/s00125-006-0316-2
    325 rdf:type schema:CreativeWork
    326 sg:pub.10.1007/s00125-006-0340-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012299813
    327 https://doi.org/10.1007/s00125-006-0340-2
    328 rdf:type schema:CreativeWork
    329 sg:pub.10.1007/s00125-007-0911-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1034961770
    330 https://doi.org/10.1007/s00125-007-0911-x
    331 rdf:type schema:CreativeWork
    332 sg:pub.10.1007/s00125-008-1157-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1018087341
    333 https://doi.org/10.1007/s00125-008-1157-y
    334 rdf:type schema:CreativeWork
    335 sg:pub.10.1007/s00125-008-1236-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053708663
    336 https://doi.org/10.1007/s00125-008-1236-0
    337 rdf:type schema:CreativeWork
    338 sg:pub.10.1007/s00125-009-1440-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041996770
    339 https://doi.org/10.1007/s00125-009-1440-6
    340 rdf:type schema:CreativeWork
    341 sg:pub.10.1007/s00125-009-1468-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003702735
    342 https://doi.org/10.1007/s00125-009-1468-7
    343 rdf:type schema:CreativeWork
    344 sg:pub.10.1007/s10557-008-6092-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003295968
    345 https://doi.org/10.1007/s10557-008-6092-0
    346 rdf:type schema:CreativeWork
    347 sg:pub.10.1007/s10557-008-6101-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006309510
    348 https://doi.org/10.1007/s10557-008-6101-3
    349 rdf:type schema:CreativeWork
    350 sg:pub.10.1186/1472-6823-9-17 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045668457
    351 https://doi.org/10.1186/1472-6823-9-17
    352 rdf:type schema:CreativeWork
    353 sg:pub.10.1186/1478-4505-4-13 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002545304
    354 https://doi.org/10.1186/1478-4505-4-13
    355 rdf:type schema:CreativeWork
    356 sg:pub.10.1186/1748-5908-3-45 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008514248
    357 https://doi.org/10.1186/1748-5908-3-45
    358 rdf:type schema:CreativeWork
    359 sg:pub.10.2165/00002018-200932070-00001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024470694
    360 https://doi.org/10.2165/00002018-200932070-00001
    361 rdf:type schema:CreativeWork
    362 https://app.dimensions.ai/details/publication/pub.1074671290 schema:CreativeWork
    363 https://app.dimensions.ai/details/publication/pub.1077526034 schema:CreativeWork
    364 https://app.dimensions.ai/details/publication/pub.1077728361 schema:CreativeWork
    365 https://app.dimensions.ai/details/publication/pub.1080690013 schema:CreativeWork
    366 https://doi.org/10.1001/archinte.164.19.2097 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012574378
    367 rdf:type schema:CreativeWork
    368 https://doi.org/10.1001/jama.296.21.joc60158 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047355148
    369 rdf:type schema:CreativeWork
    370 https://doi.org/10.1001/jama.298.10.1180 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016607544
    371 rdf:type schema:CreativeWork
    372 https://doi.org/10.1001/jama.298.10.1189 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018539400
    373 rdf:type schema:CreativeWork
    374 https://doi.org/10.1001/jama.298.2.194 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053622743
    375 rdf:type schema:CreativeWork
    376 https://doi.org/10.1001/jama.299.13.1561 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002198164
    377 rdf:type schema:CreativeWork
    378 https://doi.org/10.1002/pds.1470 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000564806
    379 rdf:type schema:CreativeWork
    380 https://doi.org/10.1002/pds.1598 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053652377
    381 rdf:type schema:CreativeWork
    382 https://doi.org/10.1002/pds.1630 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031856409
    383 rdf:type schema:CreativeWork
    384 https://doi.org/10.1016/0168-8227(95)01064-k schema:sameAs https://app.dimensions.ai/details/publication/pub.1043400052
    385 rdf:type schema:CreativeWork
    386 https://doi.org/10.1016/j.amjcard.2007.05.038 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000500727
    387 rdf:type schema:CreativeWork
    388 https://doi.org/10.1016/j.beem.2009.03.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018422376
    389 rdf:type schema:CreativeWork
    390 https://doi.org/10.1016/j.clinthera.2007.07.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037270625
    391 rdf:type schema:CreativeWork
    392 https://doi.org/10.1016/j.clinthera.2007.11.016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027653512
    393 rdf:type schema:CreativeWork
    394 https://doi.org/10.1016/j.clinthera.2008.11.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020313983
    395 rdf:type schema:CreativeWork
    396 https://doi.org/10.1016/j.diabres.2008.02.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006704575
    397 rdf:type schema:CreativeWork
    398 https://doi.org/10.1016/j.diabres.2008.04.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021927937
    399 rdf:type schema:CreativeWork
    400 https://doi.org/10.1016/j.jacc.2008.10.033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030642738
    401 rdf:type schema:CreativeWork
    402 https://doi.org/10.1016/j.jacc.2008.11.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012372299
    403 rdf:type schema:CreativeWork
    404 https://doi.org/10.1016/s0140-6736(05)67528-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029983783
    405 rdf:type schema:CreativeWork
    406 https://doi.org/10.1016/s0140-6736(06)69420-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025966136
    407 rdf:type schema:CreativeWork
    408 https://doi.org/10.1016/s0140-6736(08)60485-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052882493
    409 rdf:type schema:CreativeWork
    410 https://doi.org/10.1016/s0140-6736(08)60762-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1011950373
    411 rdf:type schema:CreativeWork
    412 https://doi.org/10.1016/s0140-6736(09)60953-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001688725
    413 rdf:type schema:CreativeWork
    414 https://doi.org/10.1016/s0140-6736(09)61969-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017470643
    415 rdf:type schema:CreativeWork
    416 https://doi.org/10.1016/s0140-6736(98)07019-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018881858
    417 rdf:type schema:CreativeWork
    418 https://doi.org/10.1016/s0140-6736(98)07037-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015697368
    419 rdf:type schema:CreativeWork
    420 https://doi.org/10.1016/s0735-1097(98)00557-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019396106
    421 rdf:type schema:CreativeWork
    422 https://doi.org/10.1053/j.gastro.2009.04.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028783747
    423 rdf:type schema:CreativeWork
    424 https://doi.org/10.1055/s-0029-1239559 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057205939
    425 rdf:type schema:CreativeWork
    426 https://doi.org/10.1055/s-2006-949655 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057466018
    427 rdf:type schema:CreativeWork
    428 https://doi.org/10.1056/nejm199309303291401 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004144761
    429 rdf:type schema:CreativeWork
    430 https://doi.org/10.1056/nejmoa052187 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045615611
    431 rdf:type schema:CreativeWork
    432 https://doi.org/10.1056/nejmoa066224 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021101828
    433 rdf:type schema:CreativeWork
    434 https://doi.org/10.1056/nejmoa072761 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010634292
    435 rdf:type schema:CreativeWork
    436 https://doi.org/10.1056/nejmoa0802743 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022234833
    437 rdf:type schema:CreativeWork
    438 https://doi.org/10.1056/nejmoa0802987 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000508710
    439 rdf:type schema:CreativeWork
    440 https://doi.org/10.1056/nejmoa0806470 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034293538
    441 rdf:type schema:CreativeWork
    442 https://doi.org/10.1056/nejmoa0905479 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036067726
    443 rdf:type schema:CreativeWork
    444 https://doi.org/10.1093/eurheartj/ehi199 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046635001
    445 rdf:type schema:CreativeWork
    446 https://doi.org/10.1093/eurheartj/ehl260 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050871132
    447 rdf:type schema:CreativeWork
    448 https://doi.org/10.1093/eurheartj/ehm124 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036766229
    449 rdf:type schema:CreativeWork
    450 https://doi.org/10.1093/eurheartj/ehm518 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038852216
    451 rdf:type schema:CreativeWork
    452 https://doi.org/10.1093/eurheartj/ehm519 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045765423
    453 rdf:type schema:CreativeWork
    454 https://doi.org/10.1093/eurheartj/ehm529 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035809392
    455 rdf:type schema:CreativeWork
    456 https://doi.org/10.1093/eurheartj/ehn114 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051704138
    457 rdf:type schema:CreativeWork
    458 https://doi.org/10.1111/j.1462-8902.2004.00325.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1018829513
    459 rdf:type schema:CreativeWork
    460 https://doi.org/10.1111/j.1463-1326.2006.00704.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1033967254
    461 rdf:type schema:CreativeWork
    462 https://doi.org/10.1111/j.1463-1326.2007.00715.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1052644745
    463 rdf:type schema:CreativeWork
    464 https://doi.org/10.1111/j.1463-1326.2008.00892.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1043304788
    465 rdf:type schema:CreativeWork
    466 https://doi.org/10.1111/j.1463-1326.2008.00994.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1036104286
    467 rdf:type schema:CreativeWork
    468 https://doi.org/10.1111/j.1464-5491.2004.01416.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1034102530
    469 rdf:type schema:CreativeWork
    470 https://doi.org/10.1111/j.1464-5491.2004.01426.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1024001006
    471 rdf:type schema:CreativeWork
    472 https://doi.org/10.1111/j.1742-1241.2008.01941.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1009611725
    473 rdf:type schema:CreativeWork
    474 https://doi.org/10.1111/j.1742-1241.2009.02025.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1028098423
    475 rdf:type schema:CreativeWork
    476 https://doi.org/10.1136/bmj.328.7454.1490 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017237059
    477 rdf:type schema:CreativeWork
    478 https://doi.org/10.1136/bmj.39314.620174.80 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040535374
    479 rdf:type schema:CreativeWork
    480 https://doi.org/10.1136/bmj.b4731 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045927678
    481 rdf:type schema:CreativeWork
    482 https://doi.org/10.1161/01.cir.99.20.2626 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048782795
    483 rdf:type schema:CreativeWork
    484 https://doi.org/10.1161/circheartfailure.108.810887 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033832697
    485 rdf:type schema:CreativeWork
    486 https://doi.org/10.1185/030079907x253870 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064132407
    487 rdf:type schema:CreativeWork
    488 https://doi.org/10.1185/030079908x253870 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012403641
    489 rdf:type schema:CreativeWork
    490 https://doi.org/10.1185/03007990902820519 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007161043
    491 rdf:type schema:CreativeWork
    492 https://doi.org/10.1210/10.1210/er.2006-0038 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064237786
    493 rdf:type schema:CreativeWork
    494 https://doi.org/10.1210/jc.2003-030861 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064287042
    495 rdf:type schema:CreativeWork
    496 https://doi.org/10.1210/jcem.86.1.7157 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064323832
    497 rdf:type schema:CreativeWork
    498 https://doi.org/10.1210/jcem.87.6.8567 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064325294
    499 rdf:type schema:CreativeWork
    500 https://doi.org/10.1517/14740330802432003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005069211
    501 rdf:type schema:CreativeWork
    502 https://doi.org/10.2147/vhrm.s1707 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069102977
    503 rdf:type schema:CreativeWork
    504 https://doi.org/10.2337/db08-1193 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019574560
    505 rdf:type schema:CreativeWork
    506 https://doi.org/10.2337/db09-9028 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004893088
    507 rdf:type schema:CreativeWork
    508 https://doi.org/10.2337/dc06-0564 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010337082
    509 rdf:type schema:CreativeWork
    510 https://doi.org/10.2337/dc08-0075 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053378796
    511 rdf:type schema:CreativeWork
    512 https://doi.org/10.2337/dc08-0167 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022873493
    513 rdf:type schema:CreativeWork
    514 https://doi.org/10.2337/dc08-1671 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018104950
    515 rdf:type schema:CreativeWork
    516 https://doi.org/10.2337/dc08-1797 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048284872
    517 rdf:type schema:CreativeWork
    518 https://doi.org/10.2337/dc08-2175 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028017606
    519 rdf:type schema:CreativeWork
    520 https://doi.org/10.2337/dc08-9017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010475808
    521 rdf:type schema:CreativeWork
    522 https://doi.org/10.2337/dc08-s001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035034566
    523 rdf:type schema:CreativeWork
    524 https://doi.org/10.2337/dc09-s013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001845211
    525 rdf:type schema:CreativeWork
    526 https://doi.org/10.2337/diacare.17.10.1100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070746175
    527 rdf:type schema:CreativeWork
    528 https://doi.org/10.2337/diacare.25.12.2244 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047089706
    529 rdf:type schema:CreativeWork
    530 https://doi.org/10.2337/diacare.28.2.260 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009165501
    531 rdf:type schema:CreativeWork
    532 https://doi.org/10.2337/diacare.29.03.06.dc05-0695 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002161808
    533 rdf:type schema:CreativeWork
    534 https://doi.org/10.7326/0003-4819-147-6-200709180-00178 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073709506
    535 rdf:type schema:CreativeWork
    536 https://doi.org/10.7326/0003-4819-147-8-200710160-00182 schema:sameAs https://app.dimensions.ai/details/publication/pub.1073709554
    537 rdf:type schema:CreativeWork
    538 https://www.grid.ac/institutes/grid.267309.9 schema:alternateName The University of Texas Health Science Center at San Antonio
    539 schema:name University of Texas Health Science Center, San Antonio, TX, USA
    540 rdf:type schema:Organization
    541 https://www.grid.ac/institutes/grid.277151.7 schema:alternateName Centre Hospitalier Universitaire de Nantes
    542 schema:name University Hospital, Nantes, France
    543 rdf:type schema:Organization
    544 https://www.grid.ac/institutes/grid.412004.3 schema:alternateName University Hospital of Zurich
    545 schema:name University Hospital Zurich, Zurich, Switzerland
    546 rdf:type schema:Organization
    547 https://www.grid.ac/institutes/grid.413303.6 schema:alternateName Krankenanstalt Rudolfstiftung der Stadt Wien
    548 schema:name Department of Medicine I, Rudolfstiftung Hospital-Vienna, Juchgasse 25, 1030, Vienna, Austria
    549 rdf:type schema:Organization
    550 https://www.grid.ac/institutes/grid.415731.5 schema:alternateName Lahey Hospital and Medical Center
    551 schema:name Lahey Clinic Medical Center, Burlington, MA, USA
    552 rdf:type schema:Organization
    553 https://www.grid.ac/institutes/grid.439749.4 schema:alternateName University College Hospital
    554 schema:name University College London Hospitals, London, UK
    555 rdf:type schema:Organization
    556 https://www.grid.ac/institutes/grid.4714.6 schema:alternateName Karolinska Institute
    557 schema:name Karolinska Institutet, Stockholm, Sweden
    558 rdf:type schema:Organization
    559 https://www.grid.ac/institutes/grid.5338.d schema:alternateName University of Valencia
    560 schema:name University of Valencia, Valencia, Spain
    561 rdf:type schema:Organization
    562 https://www.grid.ac/institutes/grid.5390.f schema:alternateName University of Udine
    563 schema:name Department of Endocrinology, University of Udine, Udine, Italy
    564 rdf:type schema:Organization
    565 https://www.grid.ac/institutes/grid.5522.0 schema:alternateName Jagiellonian University
    566 schema:name Jagiellonian University, Krakow, Poland
    567 rdf:type schema:Organization
    568 https://www.grid.ac/institutes/grid.6572.6 schema:alternateName University of Birmingham
    569 schema:name University of Birmingham and Heart of England NHS Trust, Birmingham, UK
    570 rdf:type schema:Organization
    571 https://www.grid.ac/institutes/grid.7708.8 schema:alternateName University Medical Center Freiburg
    572 schema:name University Hospital of Freiburg, Freiburg, Germany
    573 rdf:type schema:Organization
    574 https://www.grid.ac/institutes/grid.9594.1 schema:alternateName University of Ioannina
    575 schema:name University of Ioannina, Ioannina, Greece
    576 rdf:type schema:Organization
    577 https://www.grid.ac/institutes/grid.9845.0 schema:alternateName University of Latvia
    578 schema:name University of Latvia, Riga, Latvia
    579 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...