Genetic variants of HvCbf14 are statistically associated with frost tolerance in a European germplasm collection of Hordeum vulgare View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2009-09-16

AUTHORS

Agostino Fricano, Fulvia Rizza, Primetta Faccioli, Donata Pagani, Paolo Pavan, Alessandra Stella, Laura Rossini, Pietro Piffanelli, Luigi Cattivelli

ABSTRACT

Two quantitative trait loci (Fr-H1 and Fr-H2) for frost tolerance (FT) have been discovered on the long arm of chromosome 5H in barley. Two tightly linked groups of CBF genes, known to play a key role in the FT regulatory network in A. thaliana, have been found to co-segregate with Fr-H2. Here, we investigate the allelic variations of four barley CBF genes (HvCbf3, HvCbf6, HvCbf9 and HvCbf14) in a panel of European cultivars, landraces and H. spontaneum accessions. In the cultivars a reduction of nucleotide and haplotype diversities in CBFs compared with the landraces and the wild ancestor H. spontaneum, was evident. In particular, in cultivars the loss of HvCbf9 genetic variants was higher compared to other sequences. In order to verify if the pattern of CBF genetic variants correlated with the level of FT, an association procedure was adopted. The pairwise analysis of linkage disequilibrium (LD) among the genetic variants in four CBF genes was computed to evaluate the resolution of the association procedure. The pairwise plotting revealed a low level of LD in cultivated varieties, despite the tight physical linkage of CBF genes analysed. A structured association procedure based on a general liner model was implemented, including the variants in CBFs, of Vrn-H1, and of two reference genes not involved in FT (α-Amy1 and Gapdh) and considering the phenotypic data for FT. Association analysis recovered two nucleotide variants of HvCbf14 and one nucleotide variant of Vrn-H1 as statistically associated to FT. More... »

PAGES

1335-1348

References to SciGraph publications

  • 2005-11. Structural, Functional, and Phylogenetic Characterization of a Large CBF Gene Family in Barley in PLANT MOLECULAR BIOLOGY
  • 2005-02-03. Large deletions within the first intron in VRN-1 are associated with spring growth habit in barley and wheat in MOLECULAR GENETICS AND GENOMICS
  • 2008-04-16. The low temperature-responsive, SolanumCBF1 genes maintain high identity in their upstream regions in a genomic environment undergoing gene duplications, deletions, and rearrangements in PLANT MOLECULAR BIOLOGY
  • 1968-06. Linkage disequilibrium in finite populations in THEORETICAL AND APPLIED GENETICS
  • 2004-05-14. Single nucleotide polymorphism, haplotype diversity and recombination in the Isa gene of barley in THEORETICAL AND APPLIED GENETICS
  • 2005-10. Molecular and Structural Characterization of Barley Vernalization Genes in PLANT MOLECULAR BIOLOGY
  • 2003-10-24. Two loci on chromosome 5H determine low-temperature tolerance in a ‘Nure’ (winter) × ‘Tremois’ (spring) barley map in THEORETICAL AND APPLIED GENETICS
  • 2006-06-15. Identification of quantitative trait loci and associated candidate genes for low-temperature tolerance in cold-hardy winter wheat in FUNCTIONAL & INTEGRATIVE GENOMICS
  • 2005-12-16. A cluster of 11 CBF transcription factors is located at the frost tolerance locus Fr-Am2 in Triticum monococcum in MOLECULAR GENETICS AND GENOMICS
  • 2004-08-06. Linkage disequilibrium and sequence diversity in a 500-kbp region around the adh1 locus in elite maize germplasm in THEORETICAL AND APPLIED GENETICS
  • 2006-12-07. Validation of the VRN-H2/VRN-H1 epistatic model in barley reveals that intron length variation in VRN-H1 may account for a continuum of vernalization sensitivity in MOLECULAR GENETICS AND GENOMICS
  • 2008-03-04. Identification of candidate CBF genes for the frost tolerance locus Fr-Am2 in Triticummonococcum in PLANT MOLECULAR BIOLOGY
  • 2007-09-01. Fine mapping of a HvCBF gene cluster at the frost resistance locus Fr-H2 in barley in THEORETICAL AND APPLIED GENETICS
  • 1999-08-26. Primer3 on the WWW for General Users and for Biologist Programmers in BIOINFORMATICS METHODS AND PROTOCOLS
  • 2007-08-05. Recombination and linkage disequilibrium in Arabidopsis thaliana in NATURE GENETICS
  • 2002-06. Genetics and geography of wild cereal domestication in the near east in NATURE REVIEWS GENETICS
  • 2005-10-01. The expression of several Cbf genes at the Fr-A2 locus is linked to frost resistance in wheat in MOLECULAR GENETICS AND GENOMICS
  • 2007-07-19. Association mapping of Stagonospora nodorum blotch resistance in modern European winter wheat varieties in THEORETICAL AND APPLIED GENETICS
  • 2006-06-07. Haplotype structure at seven barley genes: relevance to gene pool bottlenecks, phylogeny of ear type and site of barley domestication in MOLECULAR GENETICS AND GENOMICS
  • 2007-02-07. The CBF gene family in hexaploid wheat and its relationship to the phylogenetic complexity of cereal CBFs in MOLECULAR GENETICS AND GENOMICS
  • 2001-07. Dwarf8 polymorphisms associate with variation in flowering time in NATURE GENETICS
  • 2005-12-20. Mapping of barley homologs to genes that regulate low temperature tolerance in Arabidopsis in THEORETICAL AND APPLIED GENETICS
  • 2006-05. Family-based designs in the age of large-scale gene-association studies in NATURE REVIEWS GENETICS
  • 2005-07-01. Multiple hydrophobic motifs in Arabidopsis CBF1 COOH-terminus provide functional redundancy in trans-activation in PLANT MOLECULAR BIOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00122-009-1138-7

    DOI

    http://dx.doi.org/10.1007/s00122-009-1138-7

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1046834043

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/19756475


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