Die Rolle der Pathologie in der Diagnostik des CUP-Syndroms View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-02

AUTHORS

A. Stenzinger, M. Kriegsmann, W. Weichert

ABSTRACT

Cancers of unknown primary (CUP) origin account for 2-3 % of all malignancies in Germany and represent a heterogeneous, often aggressive and clinically challenging group of tumors with early metastatic dissemination for which a standardized diagnostic work-up initially fails to identify the primary site of origin at the time of diagnosis. This article reviews the options and challenges of tissue-based conventional as well as molecular diagnostic procedures to categorize this heterogeneous group of neoplasms. The role of pathology in the diagnostics of CUP syndrome is described as part of a multidisciplinary effort involving oncologists, surgeons and radiologists with the ultimate goal of assisting clinical reasoning and decision-making. More... »

PAGES

124-133

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00117-013-2546-x

DOI

http://dx.doi.org/10.1007/s00117-013-2546-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1020641194

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24463713


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