Ontology type: schema:ScholarlyArticle Open Access: True
2020-05-11
AUTHORSAndreas Ziegler, Ekkehard Wilichowski, Ulrike Schara, Andreas Hahn, Wolfgang Müller-Felber, Jessika Johannsen, Maja von der Hagen, Arpad von Moers, Corinna Stoltenburg, Afshin Saffari, Maggie C. Walter, Ralf A. Husain, Astrid Pechmann, Cornelia Köhler, Veronka Horber, Oliver Schwartz, Janbernd Kirschner
ABSTRACTBackgroundSpinal muscular atrophy (SMA) is a severe, life-limiting neurodegenerative disease. A disease-modifying and approved therapy with nusinersen has been available in Germany since July 2017. Gene therapies offer another promising treatment option through a once in a lifetime administration. In May 2019 a gene replacement therapy for the treatment of SMA was approved for the first time by the U.S. Food and Drug Administration (FDA). An application for approval in Europe has been submitted and is currently pending.ObjectiveThis consensus paper was compiled at the invitation of the German Society for Muscular Diseases (DGM) with the participation of all potential German neuromuscular treatment centers, the German section of the Society for Pediatric Neurology (GNP) and with the involvement of the medical scientific advisory board of the DGM. The aim was to define and establish the necessary prerequisites for a safe and successful application of the new gene replacement therapy in clinical practice.ConclusionGene replacement therapy with onasemnogene abeparvovec has the potential to significantly influence the course of SMA. Long-term data on sustainability of effects and possible adverse effects of gene replacement therapy are not yet available. The application of this innovative therapy must be carried out in specialized and appropriately qualified treatment centers under strict safety conditions. This article makes suggestions for the necessary framework conditions and gives recommendations for a systematic pretreatment and posttreatment assessment schedule under gene therapy. The effectiveness and safety of the therapy should be systematically documented in an industry-independent and disease-specific register. More... »
PAGES518-529
http://scigraph.springernature.com/pub.10.1007/s00115-020-00919-8
DOIhttp://dx.doi.org/10.1007/s00115-020-00919-8
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1127514887
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/32394004
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Clinical Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Child",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Consensus",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Europe",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Genetic Therapy",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Germany",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Muscular Atrophy, Spinal",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Muscular Diseases",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Neurodegenerative Diseases",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Neurology",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Zentrum f\u00fcr Kinder- und Jugendmedizin Heidelberg, Sektion Neurop\u00e4diatrie und Stoffwechselmedizin, Universit\u00e4tsklinikum Heidelberg, Im Neuenheimer Feld\u00a0430, 69120, Heidelberg, Deutschland",
"id": "http://www.grid.ac/institutes/grid.5253.1",
"name": [
"Zentrum f\u00fcr Kinder- und Jugendmedizin Heidelberg, Sektion Neurop\u00e4diatrie und Stoffwechselmedizin, Universit\u00e4tsklinikum Heidelberg, Im Neuenheimer Feld\u00a0430, 69120, Heidelberg, Deutschland"
],
"type": "Organization"
},
"familyName": "Ziegler",
"givenName": "Andreas",
"id": "sg:person.01207532423.34",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01207532423.34"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Abteilung Neurop\u00e4diatrie und Sozialp\u00e4diatrie, Klinik f\u00fcr Kinder- und Jugendmedizin, Universit\u00e4tsmedizin G\u00f6ttingen, G\u00f6ttingen, Deutschland",
"id": "http://www.grid.ac/institutes/grid.411984.1",
"name": [
"Abteilung Neurop\u00e4diatrie und Sozialp\u00e4diatrie, Klinik f\u00fcr Kinder- und Jugendmedizin, Universit\u00e4tsmedizin G\u00f6ttingen, G\u00f6ttingen, Deutschland"
],
"type": "Organization"
},
"familyName": "Wilichowski",
"givenName": "Ekkehard",
"id": "sg:person.01130007500.10",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01130007500.10"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Abteilung f\u00fcr Neurop\u00e4diatrie, Zentrum f\u00fcr neuromuskul\u00e4re Erkrankungen des Kindes- und Jugendalters, Universit\u00e4tsklinikum Essen, Universit\u00e4t Duisburg-Essen, Essen, Deutschland",
"id": "http://www.grid.ac/institutes/grid.410718.b",
"name": [
"Abteilung f\u00fcr Neurop\u00e4diatrie, Zentrum f\u00fcr neuromuskul\u00e4re Erkrankungen des Kindes- und Jugendalters, Universit\u00e4tsklinikum Essen, Universit\u00e4t Duisburg-Essen, Essen, Deutschland"
],
"type": "Organization"
},
"familyName": "Schara",
"givenName": "Ulrike",
"id": "sg:person.01133657416.38",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01133657416.38"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Abteilung Kinderneurologie, Sozialp\u00e4diatrie und Epileptologie, Zentrum Kinderheilkunde, Justus-Liebig-Universit\u00e4t, Gie\u00dfen, Deutschland",
"id": "http://www.grid.ac/institutes/grid.8664.c",
"name": [
"Abteilung Kinderneurologie, Sozialp\u00e4diatrie und Epileptologie, Zentrum Kinderheilkunde, Justus-Liebig-Universit\u00e4t, Gie\u00dfen, Deutschland"
],
"type": "Organization"
},
"familyName": "Hahn",
"givenName": "Andreas",
"id": "sg:person.0721031255.31",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721031255.31"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Dr. v. Hauner\u2019sche Kinderklinik, Universit\u00e4tskinderklinik, Ludwig-Maximilians-Universit\u00e4t, M\u00fcnchen, Deutschland",
"id": "http://www.grid.ac/institutes/grid.411095.8",
"name": [
"Dr. v. Hauner\u2019sche Kinderklinik, Universit\u00e4tskinderklinik, Ludwig-Maximilians-Universit\u00e4t, M\u00fcnchen, Deutschland"
],
"type": "Organization"
},
"familyName": "M\u00fcller-Felber",
"givenName": "Wolfgang",
"id": "sg:person.01147147152.72",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01147147152.72"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Neurop\u00e4diatrie, Klinik und Poliklinik f\u00fcr Kinder- und Jugendmedizin, Universit\u00e4tsklinikum Hamburg-Eppendorf, Hamburg, Deutschland",
"id": "http://www.grid.ac/institutes/grid.13648.38",
"name": [
"Neurop\u00e4diatrie, Klinik und Poliklinik f\u00fcr Kinder- und Jugendmedizin, Universit\u00e4tsklinikum Hamburg-Eppendorf, Hamburg, Deutschland"
],
"type": "Organization"
},
"familyName": "Johannsen",
"givenName": "Jessika",
"id": "sg:person.0715660253.99",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0715660253.99"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Abteilung Neurop\u00e4diatrie, Medizinische Fakult\u00e4t Carl Gustav Carus, Technische Universit\u00e4t Dresden, Dresden, Deutschland",
"id": "http://www.grid.ac/institutes/grid.4488.0",
"name": [
"Abteilung Neurop\u00e4diatrie, Medizinische Fakult\u00e4t Carl Gustav Carus, Technische Universit\u00e4t Dresden, Dresden, Deutschland"
],
"type": "Organization"
},
"familyName": "von der Hagen",
"givenName": "Maja",
"id": "sg:person.0700502521.18",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0700502521.18"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Klinik f\u00fcr Kinder- und Jugendmedizin, DRK Kliniken Berlin, Berlin, Deutschland",
"id": "http://www.grid.ac/institutes/grid.500030.6",
"name": [
"Klinik f\u00fcr Kinder- und Jugendmedizin, DRK Kliniken Berlin, Berlin, Deutschland"
],
"type": "Organization"
},
"familyName": "von Moers",
"givenName": "Arpad",
"id": "sg:person.01155171261.36",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01155171261.36"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Sozialp\u00e4diatrisches Zentrum, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Berlin, Deutschland",
"id": "http://www.grid.ac/institutes/grid.6363.0",
"name": [
"Sozialp\u00e4diatrisches Zentrum, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Berlin, Deutschland"
],
"type": "Organization"
},
"familyName": "Stoltenburg",
"givenName": "Corinna",
"id": "sg:person.014531632247.82",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014531632247.82"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Zentrum f\u00fcr Kinder- und Jugendmedizin Heidelberg, Sektion Neurop\u00e4diatrie und Stoffwechselmedizin, Universit\u00e4tsklinikum Heidelberg, Im Neuenheimer Feld\u00a0430, 69120, Heidelberg, Deutschland",
"id": "http://www.grid.ac/institutes/grid.5253.1",
"name": [
"Zentrum f\u00fcr Kinder- und Jugendmedizin Heidelberg, Sektion Neurop\u00e4diatrie und Stoffwechselmedizin, Universit\u00e4tsklinikum Heidelberg, Im Neuenheimer Feld\u00a0430, 69120, Heidelberg, Deutschland"
],
"type": "Organization"
},
"familyName": "Saffari",
"givenName": "Afshin",
"id": "sg:person.01322611423.37",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01322611423.37"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Friedrich-Baur-Institut, Neurologische Klinik und Poliklinik, Ludwig-Maximilians-Universit\u00e4t, M\u00fcnchen, Deutschland",
"id": "http://www.grid.ac/institutes/grid.5252.0",
"name": [
"Friedrich-Baur-Institut, Neurologische Klinik und Poliklinik, Ludwig-Maximilians-Universit\u00e4t, M\u00fcnchen, Deutschland"
],
"type": "Organization"
},
"familyName": "Walter",
"givenName": "Maggie C.",
"id": "sg:person.01004405606.60",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01004405606.60"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Klinik f\u00fcr Neurop\u00e4diatrie, Universit\u00e4tsklinikum Jena, Jena, Deutschland",
"id": "http://www.grid.ac/institutes/grid.275559.9",
"name": [
"Klinik f\u00fcr Neurop\u00e4diatrie, Universit\u00e4tsklinikum Jena, Jena, Deutschland"
],
"type": "Organization"
},
"familyName": "Husain",
"givenName": "Ralf A.",
"id": "sg:person.01255655775.30",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01255655775.30"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Klinik f\u00fcr Neurop\u00e4diatrie und Muskelerkrankungen, Zentrum f\u00fcr Kinder- und Jugendmedizin, Universit\u00e4tsklinikum Freiburg, Medizinische Fakult\u00e4t, Albert-Ludwigs-Universit\u00e4t Freiburg, Freiburg, Deutschland",
"id": "http://www.grid.ac/institutes/grid.5963.9",
"name": [
"Klinik f\u00fcr Neurop\u00e4diatrie und Muskelerkrankungen, Zentrum f\u00fcr Kinder- und Jugendmedizin, Universit\u00e4tsklinikum Freiburg, Medizinische Fakult\u00e4t, Albert-Ludwigs-Universit\u00e4t Freiburg, Freiburg, Deutschland"
],
"type": "Organization"
},
"familyName": "Pechmann",
"givenName": "Astrid",
"id": "sg:person.0707430255.92",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707430255.92"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Abteilung f\u00fcr Neurop\u00e4diatrie mit Sozialp\u00e4diatrie, Klinik f\u00fcr Kinder- und Jugendmedizin, Ruhr-Universit\u00e4t Bochum, Bochum, Deutschland",
"id": "http://www.grid.ac/institutes/grid.5570.7",
"name": [
"Abteilung f\u00fcr Neurop\u00e4diatrie mit Sozialp\u00e4diatrie, Klinik f\u00fcr Kinder- und Jugendmedizin, Ruhr-Universit\u00e4t Bochum, Bochum, Deutschland"
],
"type": "Organization"
},
"familyName": "K\u00f6hler",
"givenName": "Cornelia",
"id": "sg:person.01052673126.62",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01052673126.62"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Abteilung Neurop\u00e4diatrie, Entwicklungsneurologie und Sozialp\u00e4diatrie, Universit\u00e4tsklinik f\u00fcr Kinder- und Jugendmedizin, T\u00fcbingen, Deutschland",
"id": "http://www.grid.ac/institutes/grid.488549.c",
"name": [
"Abteilung Neurop\u00e4diatrie, Entwicklungsneurologie und Sozialp\u00e4diatrie, Universit\u00e4tsklinik f\u00fcr Kinder- und Jugendmedizin, T\u00fcbingen, Deutschland"
],
"type": "Organization"
},
"familyName": "Horber",
"givenName": "Veronka",
"id": "sg:person.01327662273.91",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01327662273.91"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Abteilung f\u00fcr Allgemeine P\u00e4diatrie \u2013 Neurop\u00e4diatrie, Klinik f\u00fcr Kinder- und Jugendmedizin, Universit\u00e4tsklinikum M\u00fcnster, M\u00fcnster, Deutschland",
"id": "http://www.grid.ac/institutes/grid.16149.3b",
"name": [
"Abteilung f\u00fcr Allgemeine P\u00e4diatrie \u2013 Neurop\u00e4diatrie, Klinik f\u00fcr Kinder- und Jugendmedizin, Universit\u00e4tsklinikum M\u00fcnster, M\u00fcnster, Deutschland"
],
"type": "Organization"
},
"familyName": "Schwartz",
"givenName": "Oliver",
"id": "sg:person.013150304271.05",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013150304271.05"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Abteilung Neurop\u00e4diatrie und Sozialp\u00e4diatrisches Zentrum, Zentrum f\u00fcr Kinderheilkunde, Universit\u00e4tsklinikum Bonn, Bonn, Deutschland",
"id": "http://www.grid.ac/institutes/grid.470032.2",
"name": [
"Abteilung Neurop\u00e4diatrie und Sozialp\u00e4diatrisches Zentrum, Zentrum f\u00fcr Kinderheilkunde, Universit\u00e4tsklinikum Bonn, Bonn, Deutschland"
],
"type": "Organization"
},
"familyName": "Kirschner",
"givenName": "Janbernd",
"id": "sg:person.0717435623.02",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0717435623.02"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1038/s41573-019-0012-9",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1111832441",
"https://doi.org/10.1038/s41573-019-0012-9"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ng.3389",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009452373",
"https://doi.org/10.1038/ng.3389"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/s13023-019-0998-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1111576845",
"https://doi.org/10.1186/s13023-019-0998-4"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00018-018-2849-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1104408852",
"https://doi.org/10.1007/s00018-018-2849-1"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00115-019-0761-z",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1117831515",
"https://doi.org/10.1007/s00115-019-0761-z"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nbt.1610",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026693143",
"https://doi.org/10.1038/nbt.1610"
],
"type": "CreativeWork"
}
],
"datePublished": "2020-05-11",
"datePublishedReg": "2020-05-11",
"description": "BackgroundSpinal muscular atrophy (SMA) is a\u00a0severe, life-limiting neurodegenerative disease. A\u00a0disease-modifying and approved therapy with nusinersen has been available in Germany since July 2017. Gene therapies offer another promising treatment option through a once in a lifetime administration. In May 2019 a\u00a0gene replacement therapy for the treatment of SMA was approved for the first time by the U.S. Food and Drug Administration (FDA). An application for approval in Europe has been submitted and is currently pending.ObjectiveThis consensus paper was compiled at the invitation of the German Society for Muscular Diseases (DGM) with the participation of all potential German neuromuscular treatment centers, the German section of the Society for Pediatric Neurology (GNP) and with the involvement of the medical scientific advisory board of the DGM. The aim was to define and establish the necessary prerequisites for a\u00a0safe and successful application of the new gene replacement therapy in clinical practice.ConclusionGene replacement therapy with onasemnogene abeparvovec has the potential to significantly influence the course of SMA. Long-term data on sustainability of effects and possible adverse effects of gene replacement therapy are not yet available. The application of this innovative therapy must be carried out in specialized and appropriately qualified treatment centers under strict safety conditions. This article makes suggestions for the necessary framework conditions and gives recommendations for a\u00a0systematic pretreatment and posttreatment assessment schedule under gene therapy. The effectiveness and safety of the therapy should be systematically documented in an industry-independent and disease-specific register.",
"genre": "article",
"id": "sg:pub.10.1007/s00115-020-00919-8",
"inLanguage": "de",
"isAccessibleForFree": true,
"isPartOf": [
{
"id": "sg:journal.1018193",
"issn": [
"0028-2804",
"1433-0407"
],
"name": "Der Nervenarzt",
"publisher": "Springer Nature",
"type": "Periodical"
},
{
"issueNumber": "6",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "91"
}
],
"keywords": [
"replacement therapy",
"gene replacement therapy",
"treatment centers",
"Medical Scientific Advisory Board",
"BackgroundSpinal muscular atrophy",
"promising treatment option",
"disease-specific register",
"sustainability of effects",
"possible adverse effects",
"gene therapy",
"lifetime administration",
"treatment options",
"onasemnogene abeparvovec",
"pediatric neurology",
"Assessment Schedule",
"consensus paper",
"clinical practice",
"innovative therapies",
"Drug Administration",
"muscular atrophy",
"therapy",
"Scientific Advisory Board",
"neurodegenerative diseases",
"systematic pretreatment",
"U.S. Food",
"adverse effects",
"muscular diseases",
"long-term data",
"disease",
"administration",
"German Society",
"Advisory Board",
"atrophy",
"nusinersen",
"neurology",
"treatment",
"center",
"Register",
"approval",
"involvement",
"pretreatment",
"SMA",
"safety",
"effect",
"options",
"aim",
"course",
"food",
"recommendations",
"schedule",
"necessary prerequisite",
"first time",
"practice",
"German section",
"invitation",
"data",
"participation",
"conditions",
"effectiveness",
"time",
"potential",
"society",
"safety conditions",
"sections",
"prerequisite",
"suggestions",
"Germany",
"necessary framework conditions",
"article",
"board",
"Europe",
"successful application",
"DERs",
"DGM",
"applications",
"sustainability",
"framework conditions",
"paper"
],
"name": "Handlungsempfehlungen zur Gentherapie der spinalen Muskelatrophie mit Onasemnogene Abeparvovec \u2013 AVXS-101",
"pagination": "518-529",
"productId": [
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1127514887"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s00115-020-00919-8"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"32394004"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s00115-020-00919-8",
"https://app.dimensions.ai/details/publication/pub.1127514887"
],
"sdDataset": "articles",
"sdDatePublished": "2022-06-01T22:22",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-springernature-scigraph/baseset/20220601/entities/gbq_results/article/article_838.jsonl",
"type": "ScholarlyArticle",
"url": "https://doi.org/10.1007/s00115-020-00919-8"
}
]
Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00115-020-00919-8'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00115-020-00919-8'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00115-020-00919-8'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00115-020-00919-8'
This table displays all metadata directly associated to this object as RDF triples.
361 TRIPLES
22 PREDICATES
119 URIs
105 LITERALS
17 BLANK NODES