Pathogenese und Prävention des M. Alzheimer View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2013-03-20

AUTHORS

H. Braak, S. Feldengut, K. Del Tredici

ABSTRACT

Abnormal tau lesions (e.g., pretangles, neuropil threads, and neurofibrillary tangles) that develop in a few types of nerve cells in the central nervous system are essential to the pathogenesis of Alzheimer’s disease. Pretangles begin to occur in puberty and even during early childhood in the locus coeruleus. Evolutionally speaking, the propensity to develop tau lesions may be related to late developing and maturing nerve cell types in the human brain. More... »

PAGES

477-482

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00115-012-3688-1

DOI

http://dx.doi.org/10.1007/s00115-012-3688-1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1048843456

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/23508204


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