Bedeutung der Hypothermie in der Traumatologie View Full Text


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Article Info

DATE

2009-12

AUTHORS

P. Kobbe, P. Lichte, M. Wellmann, F. Hildebrand, D. Nast-Kolb, C. Waydhas, R. Oberbeck

ABSTRACT

Accidental hypothermia is a common complication in severely injured patients. Risk factors include environmental exposure of the patient at the accident site or in the clinic, infusion of cold fluids, hemorrhagic shock and anesthetics which influence thermoregulation. In contrast to animal studies, human studies and clinical experiences have identified accidental hypothermia of the severely injured patient to be associated with increased complication and mortality rates. As a consequence, hypothermia together with acidosis and coagulopathy, have been coined the lethal triad in severely injured patients. On a cellular level hypothermia reduces cellular activity and metabolism resulting in reduced oxygen consumption, which is therapeutically used in patients following cardiac arrest. However, the activity of important enzymes, such as those of the coagulation pathway, is simultaneously down regulated. Hypothermia-induced coagulopathy, which is refractory to substitution of coagulation factors, is a major complication of hypothermia in traumatized patients. Therefore, hypothermic trauma patients with hemodynamic instability require aggressive rewarming. More... »

PAGES

1055-1061

References to SciGraph publications

  • 2008-02. Therapeutische Hypothermie in DER ANAESTHESIST
  • 2003-10. Hypothermia in the management of traumatic brain injury in INTENSIVE CARE MEDICINE
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00113-009-1711-1

    DOI

    http://dx.doi.org/10.1007/s00113-009-1711-1

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1004427458

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/19998020


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    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00113-009-1711-1'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00113-009-1711-1'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00113-009-1711-1'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00113-009-1711-1'


     

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