Allergenspezifische Immuntherapie bei IgE-vermittelten Erkrankungen im Kindes- und Jugendalter View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2019-01

AUTHORS

Z. Szépfalusi, F. Horak Jr, T. Eiwegger, E. Horak, I. Huttegger, S. Wolf-Abdolvahab, E.‑M. Varga, J. Riedler, AG Pneumologie und Allergologie der Österreichischen Gesellschaft für Kinder- und Jugendheilkunde

ABSTRACT

Der Konsensusreport 2009 zur allergenspezifischen Immuntherapie (AIT) bei IgE-vermittelten (Ig: Immunglobulin) allergischen Erkrankungen im Kindes- und Jugendalter ist aufgrund zunehmend größerer Angebote an Allergenpräparaten und der sehr heterogenen Studienlage entstanden. Mittlerweile erfährt die Landschaft der Immuntherapie eine deutliche Umgestaltung (Verordnung der Europäischen Union [EU], Therapie-Allergene-Verordnung etc.). Geblieben ist die ethische Verpflichtung, Kinder und Jugendliche möglichst mit Allergenpräparaten zu behandeln, die auch in Studien an Kindern und Jugendlichen geprüft sowie als wirksam und sicher eingestuft worden sind (EU-Regulative, European Medicines Agency [EMA]). Die 2017 aktualisierte, für Österreich geltende Liste der Immuntherapiepräparate mit besonderem Bezug zu Kindern und Jugendlichen wurde nunmehr angepasst. Eine kritische Betrachtung der Studienlandschaft wurde abermals verfolgt. Einige neu auf den Markt gekommene Immuntherapieprodukte zeigen eine verbesserte Datenlage aus Studien, die ausschließlich an Kindern und Jugendlichen durchgeführt wurden. Daher können diese zugelassenen und lizensierten Produkte zur indikationsgerechten Verwendung bei Kindern und Jugendlichen empfohlen werden. More... »

PAGES

1-21

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00112-018-0448-8

DOI

http://dx.doi.org/10.1007/s00112-018-0448-8

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1101360306


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