Schwerwiegende Nebenwirkungen durch nasales Xylometazolin View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2013-06

AUTHORS

H.-G. Topf, B. Schwarze, H. Köhler, A. Neubert, W. Rascher

ABSTRACT

Trotz des hohen Risikos schwerer Nebenwirkungen sind lokal anzuwendende Sympathomimetika in Deutschland frei verkäuflich und in ihrer Anwendung weit verbreitet. Wir berichten über ein 30 Tage altes Mädchen welches 3-mal täglich 0,1 ml 0,05 %iger Xylometazolinlösung erhalten hatte. Wegen Erbrechen, Apnoe und Bewusstlosigkeit wurde das Kind auf die pädiatrische Intensivstation aufgenommen. Massenspektrometrisch zeigte sich eine hohe Konzentration von Xylometazolin und seiner Metaboliten im Urin der Patientin; ein Zusammenhang zwischen der Xylometazolingabe und den Symptomen konnte klar nachgewiesen werden. Es soll ausdrücklich vor der unkritischen Anwendung zwar nichtverschreibungspflichtiger, aber für Säuglinge und Kleinkinder potenziell gefährlicher Medikamente gewarnt werden. More... »

PAGES

537-542

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00112-013-2926-3

DOI

http://dx.doi.org/10.1007/s00112-013-2926-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1028222255


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