Akute disseminierte Enzephalomyelitis und Schleimhautulzerationen View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2006-05

AUTHORS

G. M. Lackmann, S. Lyding, A. Scherer, T. Niehues

ABSTRACT

Case reportWe report the case of a 15-year-old Libyan girl who developed headache, gait disturbances, and vomiting in Libya. Due to multiple high-density lesions in the T2-weighted MRI pictures of the brain with an exceptional isolated lesion of the corpus callosum, diagnosis of acute disseminated encephalomyelitis was made. Because recurrent cycles of prednisolone treatment failed, the girl was transferred to our hospital. In addition to neurologic complaints such as gait disturbances, ataxia, and hypesthesia of both legs, she then developed uveitis as well as severe ulcerations of the mouth and genital region. Diagnosis of neuro-Behçet’s disease was made. Under treatment with prednisolone and azathioprine, the girl’s condition improved rapidly so that we were able to discharge her home after 4 weeks.Discussion The presented disease course of neuro-Behçet’s disease is quite exceptional in children, because neurologic symptoms rarely precede the typical clinical findings of Behçet’s disease in children. Furthermore, an isolated, high-density MRI lesion of the corpus callosum, like in the present case, has not been described in neuro-Behçet’s disease before. Therefore, it must be recognized that neurologic symptoms may precede Behçet’s disease by months even in children and that this disorder must be incorporated into the differential diagnosis of miscellaneous neurologic disorders. More... »

PAGES

448-450

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00112-004-1038-5

DOI

http://dx.doi.org/10.1007/s00112-004-1038-5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1016279103


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Neurosciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Kinderarztpraxis, Reinstorfweg 10a, 21107, Hamburg", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Kinderarztpraxis, Hamburg", 
            "Kinderarztpraxis, Reinstorfweg 10a, 21107, Hamburg"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lackmann", 
        "givenName": "G. M.", 
        "id": "sg:person.0777366371.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0777366371.11"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Abteilung f\u00fcr P\u00e4diatrische Immunologie und Rheumatologie, Klinik f\u00fcr Kinderonkologie, H\u00e4matologie und Immunologie, D\u00fcsseldorf", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Abteilung f\u00fcr P\u00e4diatrische Immunologie und Rheumatologie, Klinik f\u00fcr Kinderonkologie, H\u00e4matologie und Immunologie, D\u00fcsseldorf"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lyding", 
        "givenName": "S.", 
        "id": "sg:person.01247761602.90", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01247761602.90"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut f\u00fcr Diagnostische Radiologie, Heinrich-Heine-Universit\u00e4t, D\u00fcsseldorf", 
          "id": "http://www.grid.ac/institutes/grid.411327.2", 
          "name": [
            "Institut f\u00fcr Diagnostische Radiologie, Heinrich-Heine-Universit\u00e4t, D\u00fcsseldorf"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Scherer", 
        "givenName": "A.", 
        "id": "sg:person.0627026525.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0627026525.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Abteilung f\u00fcr P\u00e4diatrische Immunologie und Rheumatologie, Klinik f\u00fcr Kinderonkologie, H\u00e4matologie und Immunologie, D\u00fcsseldorf", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Abteilung f\u00fcr P\u00e4diatrische Immunologie und Rheumatologie, Klinik f\u00fcr Kinderonkologie, H\u00e4matologie und Immunologie, D\u00fcsseldorf"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Niehues", 
        "givenName": "T.", 
        "id": "sg:person.01141443663.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01141443663.78"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s002340050343", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027455964", 
          "https://doi.org/10.1007/s002340050343"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2006-05", 
    "datePublishedReg": "2006-05-01", 
    "description": "Case reportWe report the case of a 15-year-old Libyan girl who developed headache, gait disturbances, and vomiting in Libya. Due to multiple high-density lesions in the T2-weighted MRI pictures of the brain with an exceptional isolated lesion of the corpus callosum, diagnosis of acute disseminated encephalomyelitis was made. Because recurrent cycles of prednisolone treatment failed, the girl was transferred to our hospital. In addition to neurologic complaints such as gait disturbances, ataxia, and hypesthesia of both legs, she then developed uveitis as well as severe ulcerations of the mouth and genital region. Diagnosis of neuro-Beh\u00e7et\u2019s disease was made. Under treatment with prednisolone and azathioprine, the girl\u2019s condition improved rapidly so that we were able to discharge her home after 4 weeks.Discussion The presented disease course of neuro-Beh\u00e7et\u2019s disease is quite exceptional in children, because neurologic symptoms rarely precede the typical clinical findings of Beh\u00e7et\u2019s disease in children. Furthermore, an isolated, high-density MRI lesion of the corpus callosum, like in the present case, has not been described in neuro-Beh\u00e7et\u2019s disease before. Therefore, it must be recognized that neurologic symptoms may precede Beh\u00e7et\u2019s disease by months even in children and that this disorder must be incorporated into the differential diagnosis of miscellaneous neurologic disorders.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/s00112-004-1038-5", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1093102", 
        "issn": [
          "0026-9298", 
          "1433-0474"
        ], 
        "name": "Monatsschrift Kinderheilkunde", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "154"
      }
    ], 
    "keywords": [
      "neuro-Beh\u00e7et's disease", 
      "Beh\u00e7et's disease", 
      "gait disturbance", 
      "neurologic symptoms", 
      "corpus callosum", 
      "acute disseminated encephalomyelitis", 
      "high-density lesion", 
      "typical clinical findings", 
      "girl's condition", 
      "disseminated encephalomyelitis", 
      "prednisolone treatment", 
      "MRI lesions", 
      "disease course", 
      "isolated lesion", 
      "neurologic complaints", 
      "clinical findings", 
      "severe ulceration", 
      "neurologic disorders", 
      "differential diagnosis", 
      "genital region", 
      "disease", 
      "lesions", 
      "MRI pictures", 
      "diagnosis", 
      "present case", 
      "callosum", 
      "symptoms", 
      "children", 
      "disorders", 
      "treatment", 
      "girls", 
      "hypesthesia", 
      "azathioprine", 
      "uveitis", 
      "encephalomyelitis", 
      "prednisolone", 
      "ulceration", 
      "headache", 
      "hospital", 
      "complaints", 
      "ataxia", 
      "cases", 
      "brain", 
      "weeks", 
      "months", 
      "leg", 
      "disturbances", 
      "T2", 
      "recurrent cycles", 
      "findings", 
      "course", 
      "mouth", 
      "home", 
      "addition", 
      "conditions", 
      "picture", 
      "cycle", 
      "region", 
      "discussion", 
      "Libya"
    ], 
    "name": "Akute disseminierte Enzephalomyelitis und Schleimhautulzerationen", 
    "pagination": "448-450", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1016279103"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00112-004-1038-5"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00112-004-1038-5", 
      "https://app.dimensions.ai/details/publication/pub.1016279103"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-05-20T07:23", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220519/entities/gbq_results/article/article_413.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/s00112-004-1038-5"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00112-004-1038-5'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00112-004-1038-5'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00112-004-1038-5'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00112-004-1038-5'


 

This table displays all metadata directly associated to this object as RDF triples.

149 TRIPLES      22 PREDICATES      87 URIs      78 LITERALS      6 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00112-004-1038-5 schema:about anzsrc-for:11
2 anzsrc-for:1109
3 schema:author N8f8f67571dc049f6993cbfa6de541755
4 schema:citation sg:pub.10.1007/s002340050343
5 schema:datePublished 2006-05
6 schema:datePublishedReg 2006-05-01
7 schema:description Case reportWe report the case of a 15-year-old Libyan girl who developed headache, gait disturbances, and vomiting in Libya. Due to multiple high-density lesions in the T2-weighted MRI pictures of the brain with an exceptional isolated lesion of the corpus callosum, diagnosis of acute disseminated encephalomyelitis was made. Because recurrent cycles of prednisolone treatment failed, the girl was transferred to our hospital. In addition to neurologic complaints such as gait disturbances, ataxia, and hypesthesia of both legs, she then developed uveitis as well as severe ulcerations of the mouth and genital region. Diagnosis of neuro-Behçet’s disease was made. Under treatment with prednisolone and azathioprine, the girl’s condition improved rapidly so that we were able to discharge her home after 4 weeks.Discussion The presented disease course of neuro-Behçet’s disease is quite exceptional in children, because neurologic symptoms rarely precede the typical clinical findings of Behçet’s disease in children. Furthermore, an isolated, high-density MRI lesion of the corpus callosum, like in the present case, has not been described in neuro-Behçet’s disease before. Therefore, it must be recognized that neurologic symptoms may precede Behçet’s disease by months even in children and that this disorder must be incorporated into the differential diagnosis of miscellaneous neurologic disorders.
8 schema:genre article
9 schema:inLanguage en
10 schema:isAccessibleForFree false
11 schema:isPartOf N35ae15d22f754689a7064c9f1741c940
12 Nacbd3561860b468e97f8d0dfa489202a
13 sg:journal.1093102
14 schema:keywords Behçet's disease
15 Libya
16 MRI lesions
17 MRI pictures
18 T2
19 acute disseminated encephalomyelitis
20 addition
21 ataxia
22 azathioprine
23 brain
24 callosum
25 cases
26 children
27 clinical findings
28 complaints
29 conditions
30 corpus callosum
31 course
32 cycle
33 diagnosis
34 differential diagnosis
35 discussion
36 disease
37 disease course
38 disorders
39 disseminated encephalomyelitis
40 disturbances
41 encephalomyelitis
42 findings
43 gait disturbance
44 genital region
45 girl's condition
46 girls
47 headache
48 high-density lesion
49 home
50 hospital
51 hypesthesia
52 isolated lesion
53 leg
54 lesions
55 months
56 mouth
57 neuro-Behçet's disease
58 neurologic complaints
59 neurologic disorders
60 neurologic symptoms
61 picture
62 prednisolone
63 prednisolone treatment
64 present case
65 recurrent cycles
66 region
67 severe ulceration
68 symptoms
69 treatment
70 typical clinical findings
71 ulceration
72 uveitis
73 weeks
74 schema:name Akute disseminierte Enzephalomyelitis und Schleimhautulzerationen
75 schema:pagination 448-450
76 schema:productId Ndefd53d4cc4d4e8e8646a9fb76983809
77 Nf98ef68272524f239d577c62de95f15e
78 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016279103
79 https://doi.org/10.1007/s00112-004-1038-5
80 schema:sdDatePublished 2022-05-20T07:23
81 schema:sdLicense https://scigraph.springernature.com/explorer/license/
82 schema:sdPublisher N0d924f422fd04727a6c4f5724dc39e9d
83 schema:url https://doi.org/10.1007/s00112-004-1038-5
84 sgo:license sg:explorer/license/
85 sgo:sdDataset articles
86 rdf:type schema:ScholarlyArticle
87 N0d924f422fd04727a6c4f5724dc39e9d schema:name Springer Nature - SN SciGraph project
88 rdf:type schema:Organization
89 N35ae15d22f754689a7064c9f1741c940 schema:issueNumber 5
90 rdf:type schema:PublicationIssue
91 N5ee0395d02d2497bbc5214482ed26192 rdf:first sg:person.0627026525.04
92 rdf:rest Na032632982b24e8e83bde29a1f1aac3e
93 N8f8f67571dc049f6993cbfa6de541755 rdf:first sg:person.0777366371.11
94 rdf:rest Nc15e83ec93ee48a082dd78d0b85d6409
95 Na032632982b24e8e83bde29a1f1aac3e rdf:first sg:person.01141443663.78
96 rdf:rest rdf:nil
97 Nacbd3561860b468e97f8d0dfa489202a schema:volumeNumber 154
98 rdf:type schema:PublicationVolume
99 Nc15e83ec93ee48a082dd78d0b85d6409 rdf:first sg:person.01247761602.90
100 rdf:rest N5ee0395d02d2497bbc5214482ed26192
101 Ndefd53d4cc4d4e8e8646a9fb76983809 schema:name doi
102 schema:value 10.1007/s00112-004-1038-5
103 rdf:type schema:PropertyValue
104 Nf98ef68272524f239d577c62de95f15e schema:name dimensions_id
105 schema:value pub.1016279103
106 rdf:type schema:PropertyValue
107 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
108 schema:name Medical and Health Sciences
109 rdf:type schema:DefinedTerm
110 anzsrc-for:1109 schema:inDefinedTermSet anzsrc-for:
111 schema:name Neurosciences
112 rdf:type schema:DefinedTerm
113 sg:journal.1093102 schema:issn 0026-9298
114 1433-0474
115 schema:name Monatsschrift Kinderheilkunde
116 schema:publisher Springer Nature
117 rdf:type schema:Periodical
118 sg:person.01141443663.78 schema:affiliation grid-institutes:None
119 schema:familyName Niehues
120 schema:givenName T.
121 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01141443663.78
122 rdf:type schema:Person
123 sg:person.01247761602.90 schema:affiliation grid-institutes:None
124 schema:familyName Lyding
125 schema:givenName S.
126 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01247761602.90
127 rdf:type schema:Person
128 sg:person.0627026525.04 schema:affiliation grid-institutes:grid.411327.2
129 schema:familyName Scherer
130 schema:givenName A.
131 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0627026525.04
132 rdf:type schema:Person
133 sg:person.0777366371.11 schema:affiliation grid-institutes:None
134 schema:familyName Lackmann
135 schema:givenName G. M.
136 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0777366371.11
137 rdf:type schema:Person
138 sg:pub.10.1007/s002340050343 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027455964
139 https://doi.org/10.1007/s002340050343
140 rdf:type schema:CreativeWork
141 grid-institutes:None schema:alternateName Abteilung für Pädiatrische Immunologie und Rheumatologie, Klinik für Kinderonkologie, Hämatologie und Immunologie, Düsseldorf
142 Kinderarztpraxis, Reinstorfweg 10a, 21107, Hamburg
143 schema:name Abteilung für Pädiatrische Immunologie und Rheumatologie, Klinik für Kinderonkologie, Hämatologie und Immunologie, Düsseldorf
144 Kinderarztpraxis, Hamburg
145 Kinderarztpraxis, Reinstorfweg 10a, 21107, Hamburg
146 rdf:type schema:Organization
147 grid-institutes:grid.411327.2 schema:alternateName Institut für Diagnostische Radiologie, Heinrich-Heine-Universität, Düsseldorf
148 schema:name Institut für Diagnostische Radiologie, Heinrich-Heine-Universität, Düsseldorf
149 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...