Ontology type: schema:ScholarlyArticle Open Access: True
2021-11-04
AUTHORSGabryella S. P. Santos, Alinne C. Costa, Caroline C. Picoli, Beatriz G. S. Rocha, Sheu O. Sulaiman, Debora C. Radicchi, Mauro C. X. Pinto, Miguel L. Batista, Jaime H. Amorim, Vasco A. C. Azevedo, Rodrigo R. Resende, Niels O. S. Câmara, Akiva Mintz, Alexander Birbrair
ABSTRACTPsychological stress predisposes our body to several disorders. Understanding the cellular and molecular mechanisms involved in the physiological responses to psychological stress is essential for the success of therapeutic applications. New studies show, by using in vivo inducible Cre/loxP-mediated approaches in combination with pharmacological blockage, that sympathetic nerves, activated by psychological stress, induce brown adipocytes to produce IL-6. Strikingly, this cytokine promotes gluconeogenesis in hepatocytes, that results in the decline of tolerance to inflammatory organ damage. The comprehension arising from this research will be crucial for the handling of many inflammatory diseases. Here, we review recent advances in our comprehension of the sympathetic nerve-adipocyte axis in the tissue microenvironment. More... »
PAGES151-165
http://scigraph.springernature.com/pub.10.1007/s00109-021-02157-0
DOIhttp://dx.doi.org/10.1007/s00109-021-02157-0
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/34735579
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Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00109-021-02157-0'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00109-021-02157-0'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00109-021-02157-0'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00109-021-02157-0'
This table displays all metadata directly associated to this object as RDF triples.
401 TRIPLES
22 PREDICATES
114 URIs
67 LITERALS
14 BLANK NODES