Mitochondrial complex I deficiency and cardiovascular diseases: current evidence and future directions View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2019-03-12

AUTHORS

Maurizio Forte, Silvia Palmerio, Franca Bianchi, Massimo Volpe, Speranza Rubattu

ABSTRACT

Compelling evidence demonstrates the emerging role of mitochondrial complex I deficiency in the onset and development of cardiovascular diseases (CVDs). In particular, defects in single subunits of mitochondrial complex I have been associated with cardiac hypertrophy, ischemia/reperfusion injury, as well as diabetic complications and stroke in pre-clinical studies. Moreover, data obtained in humans revealed that genes coding for complex I proteins were associated with different CVDs. In this review, we discuss recent experimental studies that underline the contributory role of mitochondrial complex I deficiency in the etiopathogenesis of several CVDs, with a particular focus on those involving loss of function models of mitochondrial complex I. We also discuss human studies and potential therapeutic strategies able to rescue mitochondrial function in CVDs. More... »

PAGES

1-13

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00109-019-01771-3

DOI

http://dx.doi.org/10.1007/s00109-019-01771-3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1112702998

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/30863992


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Istituto Neurologico Mediterraneo", 
          "id": "https://www.grid.ac/institutes/grid.419543.e", 
          "name": [
            "Department of Angiocardioneurology, IRCCS Neuromed, Localit\u00e0 Camerelle, 86077, Pozzilli, IS, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Forte", 
        "givenName": "Maurizio", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Istituto Neurologico Mediterraneo", 
          "id": "https://www.grid.ac/institutes/grid.419543.e", 
          "name": [
            "Department of Angiocardioneurology, IRCCS Neuromed, Localit\u00e0 Camerelle, 86077, Pozzilli, IS, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Palmerio", 
        "givenName": "Silvia", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Istituto Neurologico Mediterraneo", 
          "id": "https://www.grid.ac/institutes/grid.419543.e", 
          "name": [
            "Department of Angiocardioneurology, IRCCS Neuromed, Localit\u00e0 Camerelle, 86077, Pozzilli, IS, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bianchi", 
        "givenName": "Franca", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Sapienza University of Rome", 
          "id": "https://www.grid.ac/institutes/grid.7841.a", 
          "name": [
            "Department of Angiocardioneurology, IRCCS Neuromed, Localit\u00e0 Camerelle, 86077, Pozzilli, IS, Italy", 
            "Department of Clinical and Molecular Medicine, School of Medicine and Psychology, Sapienza University of Rome, Ospedale S. Andrea, Rome, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Volpe", 
        "givenName": "Massimo", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Sapienza University of Rome", 
          "id": "https://www.grid.ac/institutes/grid.7841.a", 
          "name": [
            "Department of Angiocardioneurology, IRCCS Neuromed, Localit\u00e0 Camerelle, 86077, Pozzilli, IS, Italy", 
            "Department of Clinical and Molecular Medicine, School of Medicine and Psychology, Sapienza University of Rome, Ospedale S. Andrea, Rome, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rubattu", 
        "givenName": "Speranza", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/nrcardio.2016.203", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000525101", 
          "https://doi.org/10.1038/nrcardio.2016.203"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biocel.2012.08.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002130573"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm.3212", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002336405", 
          "https://doi.org/10.1038/nm.3212"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.mito.2016.04.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002346865"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/jpi.12193", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003786983"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrcardio.2016.25", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005645110", 
          "https://doi.org/10.1038/nrcardio.2016.25"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cmet.2016.08.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005854726"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm.2507", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007707060", 
          "https://doi.org/10.1038/nm.2507"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10545-014-9768-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007934247", 
          "https://doi.org/10.1007/s10545-014-9768-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacc.2010.12.044", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008536793"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00439-001-0673-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008624631", 
          "https://doi.org/10.1007/s00439-001-0673-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00439-001-0673-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008624631", 
          "https://doi.org/10.1007/s00439-001-0673-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0378-1119(01)00814-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008652741"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m707543200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009089556"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.diabres.2006.03.024", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009153362"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199910213411706", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010029066"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/cvr/cvv183", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010188757"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2337/db11-1653", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010891460"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/cvr/cvs111", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011456924"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1155/2016/9152732", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012518705"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circresaha.111.243097", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013665884"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circresaha.111.243097", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013665884"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circresaha.111.243097", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013665884"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3390/ijms161025234", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013984724"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circheartfailure.113.000406", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014659467"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circheartfailure.113.000406", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014659467"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m109.077271", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014804901"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cmet.2013.07.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015955325"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/humu.10225", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016090896"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1113/jp271301", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017083826"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature13909", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017423660", 
          "https://doi.org/10.1038/nature13909"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m808518200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017483501"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.lfs.2016.09.021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018046171"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0094157", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019958651"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbrc.2013.07.042", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020084765"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1155/2016/1067801", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021534513"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1113987109", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022038590"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj20081386", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022066033"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj20081386", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022066033"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.res.0000109416.56608.64", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022071880"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.res.0000109416.56608.64", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022071880"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/jmedgenet-2011-100340", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022141185"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.tips.2015.08.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022379077"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10741-016-9530-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022588658", 
          "https://doi.org/10.1007/s10741-016-9530-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.18632/oncotarget.13429", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022599825"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/jmedgenet-2012-101159", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022979113"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/aps.2015.162", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023453891", 
          "https://doi.org/10.1038/aps.2015.162"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m803432200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023681497"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.res.88.5.529", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023852317"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1531-8249(20010201)49:2<195::aid-ana39>3.0.co;2-m", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024275936"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0016288", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024361177"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0016288", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024361177"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cmet.2016.03.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025035848"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cmet.2016.03.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025035848"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci39162", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025606389"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci39162", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025606389"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev-physiol-021909-135929", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025742554"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1540-8175.2011.01532.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025826556"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbabio.2006.05.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026119852"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/cns.12273", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027088029"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10863-014-9559-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027443026", 
          "https://doi.org/10.1007/s10863-014-9559-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10863-014-9559-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027443026", 
          "https://doi.org/10.1007/s10863-014-9559-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng0896-429", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027453136", 
          "https://doi.org/10.1038/ng0896-429"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbagen.2011.03.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028529188"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1074248413515750", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029186250"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1074248413515750", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029186250"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/cns.12326", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029552390"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.pharmtox.47.120505.105110", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030396639"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbabio.2016.02.013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030740592"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.tet.2015.09.014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032308290"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/gbe/evu208", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032510922"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10545-006-0362-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032621408", 
          "https://doi.org/10.1007/s10545-006-0362-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2015.10.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032641561"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/10715762.2010.509398", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033053676"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3390/ijms12107199", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033596052"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.mito.2004.09.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034266760"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.mito.2004.09.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034266760"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/fjc.0b013e31820eb8f6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035083620"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/fjc.0b013e31820eb8f6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035083620"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1134/s0006297907120139", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035943924", 
          "https://doi.org/10.1134/s0006297907120139"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijcard.2013.04.018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036551633"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.mito.2009.02.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037122584"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0803790105", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038141563"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/cvr/cvt080", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038705752"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-510x(02)00055-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039390864"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m114.550574", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039487113"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbabio.2016.01.013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039822923"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bpj.2008.10.042", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041093331"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijcard.2013.12.014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041477792"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/jaha.115.003118", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042890082"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1134/s000629790812002x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043416713", 
          "https://doi.org/10.1134/s000629790812002x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbabio.2007.07.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043626489"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m111.327866", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044310810"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.brainresbull.2015.11.019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044478800"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrm3997", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044489007", 
          "https://doi.org/10.1038/nrm3997"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3389/fcvm.2016.00038", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046107521"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/physiol.00043.2010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046373333"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa0908355", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047589742"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/jaha.115.002701", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048736790"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/jaha.115.002701", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048736790"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jtcvs.2009.08.060", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048852532"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.freeradbiomed.2015.07.160", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050119935"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacc.2012.08.1021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050869405"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1038/sj.emboj.7601748", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051024802"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/hypertensionaha.111.179457", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052216905"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/hypertensionaha.111.179457", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052216905"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/ars.2011.4123", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052291535"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature12985", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052523108", 
          "https://doi.org/10.1038/nature12985"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajpheart.00027.2014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052582908"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1530/eje-10-0995", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053005724"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.redox.2013.12.011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053466255"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/512202", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058788306"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/ars.2013.5482", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059232235"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/cvr/cvw176", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059489064"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/eurheartj/ehw333", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059577077"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajpheart.00751.2015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063194453"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2174/1389450116666151019095903", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069181605"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2174/1570159x13666150703154541", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069196057"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4239/wjd.v6.i13.1246", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1072397568"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4330/wjc.v6.i10.1091", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1072525238"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/srep41337", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074202161", 
          "https://doi.org/10.1038/srep41337"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circheartfailure.115.002206", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079221508"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circheartfailure.115.002206", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079221508"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.freeradbiomed.2017.02.036", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083851653"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ymgme.2017.05.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085166254"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/1440-1681.12768", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085198584"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3967/bes2017.037", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1085444834"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/hmg/ddx333", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091346528"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/hmg/ddx333", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1091346528"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1704723114", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1092338581"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.redox.2017.10.019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1092405809"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/japplphysiol.00670.2017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1092419545"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.redox.2017.12.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1099671769"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circheartfailure.117.004389", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1099767945"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circheartfailure.117.004389", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1099767945"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circheartfailure.117.004389", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1099767945"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.116.026099", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1099768012"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.116.026099", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1099768012"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biopha.2017.12.094", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1100076716"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbrc.2018.02.208", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1101296307"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cellsig.2018.03.012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1101819023"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/hypertensionaha.117.10787", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1103523752"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/hypertensionaha.117.10787", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1103523752"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/hypertensionaha.117.10787", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1103523752"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/hypertensionaha.117.10787", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1103523752"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/hypertensionaha.117.10787", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1103523752"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.117.032626", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1104168163"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.117.032626", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1104168163"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijcard.2018.02.021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1104508383"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10557-018-6805-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1105175242", 
          "https://doi.org/10.1007/s10557-018-6805-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.21037/atm.2018.06.21", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1105247194"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/ebc20170099", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1105733444"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.yjmcc.2018.08.022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1106360603"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ymgme.2018.10.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1107642653"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-03-12", 
    "datePublishedReg": "2019-03-12", 
    "description": "Compelling evidence demonstrates the emerging role of mitochondrial complex I deficiency in the onset and development of cardiovascular diseases (CVDs). In particular, defects in single subunits of mitochondrial complex I have been associated with cardiac hypertrophy, ischemia/reperfusion injury, as well as diabetic complications and stroke in pre-clinical studies. Moreover, data obtained in humans revealed that genes coding for complex I proteins were associated with different CVDs. In this review, we discuss recent experimental studies that underline the contributory role of mitochondrial complex I deficiency in the etiopathogenesis of several CVDs, with a particular focus on those involving loss of function models of mitochondrial complex I. We also discuss human studies and potential therapeutic strategies able to rescue mitochondrial function in CVDs.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00109-019-01771-3", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1057918", 
        "issn": [
          "0946-2716", 
          "1432-1440"
        ], 
        "name": "Journal of Molecular Medicine", 
        "type": "Periodical"
      }
    ], 
    "name": "Mitochondrial complex I deficiency and cardiovascular diseases: current evidence and future directions", 
    "pagination": "1-13", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "cc5d3b96d32a8a57d662a96a06564adbec2cac92c47f9a38226c2a84ff18066a"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "30863992"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9504370"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00109-019-01771-3"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1112702998"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00109-019-01771-3", 
      "https://app.dimensions.ai/details/publication/pub.1112702998"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T12:27", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000362_0000000362/records_87117_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2Fs00109-019-01771-3"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00109-019-01771-3'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00109-019-01771-3'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00109-019-01771-3'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00109-019-01771-3'


 

This table displays all metadata directly associated to this object as RDF triples.

495 TRIPLES      21 PREDICATES      155 URIs      18 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00109-019-01771-3 schema:about anzsrc-for:11
2 anzsrc-for:1103
3 schema:author N1cc7fc08ecf445d582f61df406e2b4e8
4 schema:citation sg:pub.10.1007/s00439-001-0673-3
5 sg:pub.10.1007/s10545-006-0362-4
6 sg:pub.10.1007/s10545-014-9768-6
7 sg:pub.10.1007/s10557-018-6805-y
8 sg:pub.10.1007/s10741-016-9530-2
9 sg:pub.10.1007/s10863-014-9559-7
10 sg:pub.10.1038/aps.2015.162
11 sg:pub.10.1038/nature12985
12 sg:pub.10.1038/nature13909
13 sg:pub.10.1038/ng0896-429
14 sg:pub.10.1038/nm.2507
15 sg:pub.10.1038/nm.3212
16 sg:pub.10.1038/nrcardio.2016.203
17 sg:pub.10.1038/nrcardio.2016.25
18 sg:pub.10.1038/nrm3997
19 sg:pub.10.1038/srep41337
20 sg:pub.10.1134/s0006297907120139
21 sg:pub.10.1134/s000629790812002x
22 https://doi.org/10.1002/1531-8249(20010201)49:2<195::aid-ana39>3.0.co;2-m
23 https://doi.org/10.1002/humu.10225
24 https://doi.org/10.1016/j.bbabio.2006.05.007
25 https://doi.org/10.1016/j.bbabio.2007.07.008
26 https://doi.org/10.1016/j.bbabio.2016.01.013
27 https://doi.org/10.1016/j.bbabio.2016.02.013
28 https://doi.org/10.1016/j.bbagen.2011.03.008
29 https://doi.org/10.1016/j.bbrc.2013.07.042
30 https://doi.org/10.1016/j.bbrc.2018.02.208
31 https://doi.org/10.1016/j.biocel.2012.08.009
32 https://doi.org/10.1016/j.biopha.2017.12.094
33 https://doi.org/10.1016/j.bpj.2008.10.042
34 https://doi.org/10.1016/j.brainresbull.2015.11.019
35 https://doi.org/10.1016/j.cell.2015.10.001
36 https://doi.org/10.1016/j.cellsig.2018.03.012
37 https://doi.org/10.1016/j.cmet.2013.07.002
38 https://doi.org/10.1016/j.cmet.2016.03.009
39 https://doi.org/10.1016/j.cmet.2016.08.012
40 https://doi.org/10.1016/j.diabres.2006.03.024
41 https://doi.org/10.1016/j.freeradbiomed.2015.07.160
42 https://doi.org/10.1016/j.freeradbiomed.2017.02.036
43 https://doi.org/10.1016/j.ijcard.2013.04.018
44 https://doi.org/10.1016/j.ijcard.2013.12.014
45 https://doi.org/10.1016/j.ijcard.2018.02.021
46 https://doi.org/10.1016/j.jacc.2010.12.044
47 https://doi.org/10.1016/j.jacc.2012.08.1021
48 https://doi.org/10.1016/j.jtcvs.2009.08.060
49 https://doi.org/10.1016/j.lfs.2016.09.021
50 https://doi.org/10.1016/j.mito.2004.09.001
51 https://doi.org/10.1016/j.mito.2009.02.001
52 https://doi.org/10.1016/j.mito.2016.04.001
53 https://doi.org/10.1016/j.redox.2013.12.011
54 https://doi.org/10.1016/j.redox.2017.10.019
55 https://doi.org/10.1016/j.redox.2017.12.006
56 https://doi.org/10.1016/j.tet.2015.09.014
57 https://doi.org/10.1016/j.tips.2015.08.012
58 https://doi.org/10.1016/j.yjmcc.2018.08.022
59 https://doi.org/10.1016/j.ymgme.2017.05.002
60 https://doi.org/10.1016/j.ymgme.2018.10.003
61 https://doi.org/10.1016/s0022-510x(02)00055-2
62 https://doi.org/10.1016/s0378-1119(01)00814-9
63 https://doi.org/10.1038/sj.emboj.7601748
64 https://doi.org/10.1042/bj20081386
65 https://doi.org/10.1042/ebc20170099
66 https://doi.org/10.1056/nejm199910213411706
67 https://doi.org/10.1056/nejmoa0908355
68 https://doi.org/10.1073/pnas.0803790105
69 https://doi.org/10.1073/pnas.1113987109
70 https://doi.org/10.1073/pnas.1704723114
71 https://doi.org/10.1074/jbc.m109.077271
72 https://doi.org/10.1074/jbc.m111.327866
73 https://doi.org/10.1074/jbc.m114.550574
74 https://doi.org/10.1074/jbc.m707543200
75 https://doi.org/10.1074/jbc.m803432200
76 https://doi.org/10.1074/jbc.m808518200
77 https://doi.org/10.1086/512202
78 https://doi.org/10.1089/ars.2011.4123
79 https://doi.org/10.1089/ars.2013.5482
80 https://doi.org/10.1093/cvr/cvs111
81 https://doi.org/10.1093/cvr/cvt080
82 https://doi.org/10.1093/cvr/cvv183
83 https://doi.org/10.1093/cvr/cvw176
84 https://doi.org/10.1093/eurheartj/ehw333
85 https://doi.org/10.1093/gbe/evu208
86 https://doi.org/10.1093/hmg/ddx333
87 https://doi.org/10.1097/fjc.0b013e31820eb8f6
88 https://doi.org/10.1111/1440-1681.12768
89 https://doi.org/10.1111/cns.12273
90 https://doi.org/10.1111/cns.12326
91 https://doi.org/10.1111/j.1540-8175.2011.01532.x
92 https://doi.org/10.1111/jpi.12193
93 https://doi.org/10.1113/jp271301
94 https://doi.org/10.1136/jmedgenet-2011-100340
95 https://doi.org/10.1136/jmedgenet-2012-101159
96 https://doi.org/10.1146/annurev-physiol-021909-135929
97 https://doi.org/10.1146/annurev.pharmtox.47.120505.105110
98 https://doi.org/10.1152/ajpheart.00027.2014
99 https://doi.org/10.1152/ajpheart.00751.2015
100 https://doi.org/10.1152/japplphysiol.00670.2017
101 https://doi.org/10.1152/physiol.00043.2010
102 https://doi.org/10.1155/2016/1067801
103 https://doi.org/10.1155/2016/9152732
104 https://doi.org/10.1161/01.res.0000109416.56608.64
105 https://doi.org/10.1161/01.res.88.5.529
106 https://doi.org/10.1161/circheartfailure.113.000406
107 https://doi.org/10.1161/circheartfailure.115.002206
108 https://doi.org/10.1161/circheartfailure.117.004389
109 https://doi.org/10.1161/circresaha.111.243097
110 https://doi.org/10.1161/circulationaha.116.026099
111 https://doi.org/10.1161/circulationaha.117.032626
112 https://doi.org/10.1161/hypertensionaha.111.179457
113 https://doi.org/10.1161/hypertensionaha.117.10787
114 https://doi.org/10.1161/jaha.115.002701
115 https://doi.org/10.1161/jaha.115.003118
116 https://doi.org/10.1172/jci39162
117 https://doi.org/10.1177/1074248413515750
118 https://doi.org/10.1371/journal.pone.0016288
119 https://doi.org/10.1371/journal.pone.0094157
120 https://doi.org/10.1530/eje-10-0995
121 https://doi.org/10.18632/oncotarget.13429
122 https://doi.org/10.21037/atm.2018.06.21
123 https://doi.org/10.2174/1389450116666151019095903
124 https://doi.org/10.2174/1570159x13666150703154541
125 https://doi.org/10.2337/db11-1653
126 https://doi.org/10.3109/10715762.2010.509398
127 https://doi.org/10.3389/fcvm.2016.00038
128 https://doi.org/10.3390/ijms12107199
129 https://doi.org/10.3390/ijms161025234
130 https://doi.org/10.3967/bes2017.037
131 https://doi.org/10.4239/wjd.v6.i13.1246
132 https://doi.org/10.4330/wjc.v6.i10.1091
133 schema:datePublished 2019-03-12
134 schema:datePublishedReg 2019-03-12
135 schema:description Compelling evidence demonstrates the emerging role of mitochondrial complex I deficiency in the onset and development of cardiovascular diseases (CVDs). In particular, defects in single subunits of mitochondrial complex I have been associated with cardiac hypertrophy, ischemia/reperfusion injury, as well as diabetic complications and stroke in pre-clinical studies. Moreover, data obtained in humans revealed that genes coding for complex I proteins were associated with different CVDs. In this review, we discuss recent experimental studies that underline the contributory role of mitochondrial complex I deficiency in the etiopathogenesis of several CVDs, with a particular focus on those involving loss of function models of mitochondrial complex I. We also discuss human studies and potential therapeutic strategies able to rescue mitochondrial function in CVDs.
136 schema:genre research_article
137 schema:inLanguage en
138 schema:isAccessibleForFree false
139 schema:isPartOf sg:journal.1057918
140 schema:name Mitochondrial complex I deficiency and cardiovascular diseases: current evidence and future directions
141 schema:pagination 1-13
142 schema:productId N4bde737c9bb647859221910e9ea548fd
143 Nade367bc3ce440f095d6c19a02c9f96f
144 Nbf8dd166a7c94421b393c6b16cdec679
145 Nf1077ca701a046949c58ec288cec0451
146 Nfa21acc1d83d4e788d65999f5ab1bf4f
147 schema:sameAs https://app.dimensions.ai/details/publication/pub.1112702998
148 https://doi.org/10.1007/s00109-019-01771-3
149 schema:sdDatePublished 2019-04-11T12:27
150 schema:sdLicense https://scigraph.springernature.com/explorer/license/
151 schema:sdPublisher N59c2c94e8ab4442aafc979410dd2061f
152 schema:url https://link.springer.com/10.1007%2Fs00109-019-01771-3
153 sgo:license sg:explorer/license/
154 sgo:sdDataset articles
155 rdf:type schema:ScholarlyArticle
156 N1cc7fc08ecf445d582f61df406e2b4e8 rdf:first N7d47fe6c6a5a440ab679d9bd81274d3a
157 rdf:rest N6e252cb0b69f43968cef3e7a3bc2f2ba
158 N4bde737c9bb647859221910e9ea548fd schema:name doi
159 schema:value 10.1007/s00109-019-01771-3
160 rdf:type schema:PropertyValue
161 N59c2c94e8ab4442aafc979410dd2061f schema:name Springer Nature - SN SciGraph project
162 rdf:type schema:Organization
163 N5d9a7124d79f42d082a6cf9201908696 schema:affiliation https://www.grid.ac/institutes/grid.419543.e
164 schema:familyName Bianchi
165 schema:givenName Franca
166 rdf:type schema:Person
167 N65f94dac7f774a75a90dd2e5c2cfbf27 rdf:first Nfbdf3a9c9171445780f5135c798d16e5
168 rdf:rest rdf:nil
169 N6e252cb0b69f43968cef3e7a3bc2f2ba rdf:first N7e93777782724be299ce01451c18ad4e
170 rdf:rest N71e9853f7bca465ba92fc0bd080194fb
171 N71e9853f7bca465ba92fc0bd080194fb rdf:first N5d9a7124d79f42d082a6cf9201908696
172 rdf:rest Nbe1ba3864e384cdfafee1dd48efdbbb5
173 N7d47fe6c6a5a440ab679d9bd81274d3a schema:affiliation https://www.grid.ac/institutes/grid.419543.e
174 schema:familyName Forte
175 schema:givenName Maurizio
176 rdf:type schema:Person
177 N7e93777782724be299ce01451c18ad4e schema:affiliation https://www.grid.ac/institutes/grid.419543.e
178 schema:familyName Palmerio
179 schema:givenName Silvia
180 rdf:type schema:Person
181 Nade367bc3ce440f095d6c19a02c9f96f schema:name readcube_id
182 schema:value cc5d3b96d32a8a57d662a96a06564adbec2cac92c47f9a38226c2a84ff18066a
183 rdf:type schema:PropertyValue
184 Nb67db4c45354424d8cf7fecec436d6e8 schema:affiliation https://www.grid.ac/institutes/grid.7841.a
185 schema:familyName Volpe
186 schema:givenName Massimo
187 rdf:type schema:Person
188 Nbe1ba3864e384cdfafee1dd48efdbbb5 rdf:first Nb67db4c45354424d8cf7fecec436d6e8
189 rdf:rest N65f94dac7f774a75a90dd2e5c2cfbf27
190 Nbf8dd166a7c94421b393c6b16cdec679 schema:name nlm_unique_id
191 schema:value 9504370
192 rdf:type schema:PropertyValue
193 Nf1077ca701a046949c58ec288cec0451 schema:name pubmed_id
194 schema:value 30863992
195 rdf:type schema:PropertyValue
196 Nfa21acc1d83d4e788d65999f5ab1bf4f schema:name dimensions_id
197 schema:value pub.1112702998
198 rdf:type schema:PropertyValue
199 Nfbdf3a9c9171445780f5135c798d16e5 schema:affiliation https://www.grid.ac/institutes/grid.7841.a
200 schema:familyName Rubattu
201 schema:givenName Speranza
202 rdf:type schema:Person
203 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
204 schema:name Medical and Health Sciences
205 rdf:type schema:DefinedTerm
206 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
207 schema:name Clinical Sciences
208 rdf:type schema:DefinedTerm
209 sg:journal.1057918 schema:issn 0946-2716
210 1432-1440
211 schema:name Journal of Molecular Medicine
212 rdf:type schema:Periodical
213 sg:pub.10.1007/s00439-001-0673-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008624631
214 https://doi.org/10.1007/s00439-001-0673-3
215 rdf:type schema:CreativeWork
216 sg:pub.10.1007/s10545-006-0362-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032621408
217 https://doi.org/10.1007/s10545-006-0362-4
218 rdf:type schema:CreativeWork
219 sg:pub.10.1007/s10545-014-9768-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007934247
220 https://doi.org/10.1007/s10545-014-9768-6
221 rdf:type schema:CreativeWork
222 sg:pub.10.1007/s10557-018-6805-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1105175242
223 https://doi.org/10.1007/s10557-018-6805-y
224 rdf:type schema:CreativeWork
225 sg:pub.10.1007/s10741-016-9530-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022588658
226 https://doi.org/10.1007/s10741-016-9530-2
227 rdf:type schema:CreativeWork
228 sg:pub.10.1007/s10863-014-9559-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027443026
229 https://doi.org/10.1007/s10863-014-9559-7
230 rdf:type schema:CreativeWork
231 sg:pub.10.1038/aps.2015.162 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023453891
232 https://doi.org/10.1038/aps.2015.162
233 rdf:type schema:CreativeWork
234 sg:pub.10.1038/nature12985 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052523108
235 https://doi.org/10.1038/nature12985
236 rdf:type schema:CreativeWork
237 sg:pub.10.1038/nature13909 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017423660
238 https://doi.org/10.1038/nature13909
239 rdf:type schema:CreativeWork
240 sg:pub.10.1038/ng0896-429 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027453136
241 https://doi.org/10.1038/ng0896-429
242 rdf:type schema:CreativeWork
243 sg:pub.10.1038/nm.2507 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007707060
244 https://doi.org/10.1038/nm.2507
245 rdf:type schema:CreativeWork
246 sg:pub.10.1038/nm.3212 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002336405
247 https://doi.org/10.1038/nm.3212
248 rdf:type schema:CreativeWork
249 sg:pub.10.1038/nrcardio.2016.203 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000525101
250 https://doi.org/10.1038/nrcardio.2016.203
251 rdf:type schema:CreativeWork
252 sg:pub.10.1038/nrcardio.2016.25 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005645110
253 https://doi.org/10.1038/nrcardio.2016.25
254 rdf:type schema:CreativeWork
255 sg:pub.10.1038/nrm3997 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044489007
256 https://doi.org/10.1038/nrm3997
257 rdf:type schema:CreativeWork
258 sg:pub.10.1038/srep41337 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074202161
259 https://doi.org/10.1038/srep41337
260 rdf:type schema:CreativeWork
261 sg:pub.10.1134/s0006297907120139 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035943924
262 https://doi.org/10.1134/s0006297907120139
263 rdf:type schema:CreativeWork
264 sg:pub.10.1134/s000629790812002x schema:sameAs https://app.dimensions.ai/details/publication/pub.1043416713
265 https://doi.org/10.1134/s000629790812002x
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1002/1531-8249(20010201)49:2<195::aid-ana39>3.0.co;2-m schema:sameAs https://app.dimensions.ai/details/publication/pub.1024275936
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1002/humu.10225 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016090896
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1016/j.bbabio.2006.05.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026119852
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1016/j.bbabio.2007.07.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043626489
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1016/j.bbabio.2016.01.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039822923
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1016/j.bbabio.2016.02.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030740592
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1016/j.bbagen.2011.03.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028529188
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1016/j.bbrc.2013.07.042 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020084765
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1016/j.bbrc.2018.02.208 schema:sameAs https://app.dimensions.ai/details/publication/pub.1101296307
284 rdf:type schema:CreativeWork
285 https://doi.org/10.1016/j.biocel.2012.08.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002130573
286 rdf:type schema:CreativeWork
287 https://doi.org/10.1016/j.biopha.2017.12.094 schema:sameAs https://app.dimensions.ai/details/publication/pub.1100076716
288 rdf:type schema:CreativeWork
289 https://doi.org/10.1016/j.bpj.2008.10.042 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041093331
290 rdf:type schema:CreativeWork
291 https://doi.org/10.1016/j.brainresbull.2015.11.019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044478800
292 rdf:type schema:CreativeWork
293 https://doi.org/10.1016/j.cell.2015.10.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032641561
294 rdf:type schema:CreativeWork
295 https://doi.org/10.1016/j.cellsig.2018.03.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1101819023
296 rdf:type schema:CreativeWork
297 https://doi.org/10.1016/j.cmet.2013.07.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015955325
298 rdf:type schema:CreativeWork
299 https://doi.org/10.1016/j.cmet.2016.03.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025035848
300 rdf:type schema:CreativeWork
301 https://doi.org/10.1016/j.cmet.2016.08.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005854726
302 rdf:type schema:CreativeWork
303 https://doi.org/10.1016/j.diabres.2006.03.024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009153362
304 rdf:type schema:CreativeWork
305 https://doi.org/10.1016/j.freeradbiomed.2015.07.160 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050119935
306 rdf:type schema:CreativeWork
307 https://doi.org/10.1016/j.freeradbiomed.2017.02.036 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083851653
308 rdf:type schema:CreativeWork
309 https://doi.org/10.1016/j.ijcard.2013.04.018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036551633
310 rdf:type schema:CreativeWork
311 https://doi.org/10.1016/j.ijcard.2013.12.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041477792
312 rdf:type schema:CreativeWork
313 https://doi.org/10.1016/j.ijcard.2018.02.021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1104508383
314 rdf:type schema:CreativeWork
315 https://doi.org/10.1016/j.jacc.2010.12.044 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008536793
316 rdf:type schema:CreativeWork
317 https://doi.org/10.1016/j.jacc.2012.08.1021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050869405
318 rdf:type schema:CreativeWork
319 https://doi.org/10.1016/j.jtcvs.2009.08.060 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048852532
320 rdf:type schema:CreativeWork
321 https://doi.org/10.1016/j.lfs.2016.09.021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018046171
322 rdf:type schema:CreativeWork
323 https://doi.org/10.1016/j.mito.2004.09.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034266760
324 rdf:type schema:CreativeWork
325 https://doi.org/10.1016/j.mito.2009.02.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037122584
326 rdf:type schema:CreativeWork
327 https://doi.org/10.1016/j.mito.2016.04.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002346865
328 rdf:type schema:CreativeWork
329 https://doi.org/10.1016/j.redox.2013.12.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053466255
330 rdf:type schema:CreativeWork
331 https://doi.org/10.1016/j.redox.2017.10.019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092405809
332 rdf:type schema:CreativeWork
333 https://doi.org/10.1016/j.redox.2017.12.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1099671769
334 rdf:type schema:CreativeWork
335 https://doi.org/10.1016/j.tet.2015.09.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032308290
336 rdf:type schema:CreativeWork
337 https://doi.org/10.1016/j.tips.2015.08.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022379077
338 rdf:type schema:CreativeWork
339 https://doi.org/10.1016/j.yjmcc.2018.08.022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1106360603
340 rdf:type schema:CreativeWork
341 https://doi.org/10.1016/j.ymgme.2017.05.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085166254
342 rdf:type schema:CreativeWork
343 https://doi.org/10.1016/j.ymgme.2018.10.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1107642653
344 rdf:type schema:CreativeWork
345 https://doi.org/10.1016/s0022-510x(02)00055-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039390864
346 rdf:type schema:CreativeWork
347 https://doi.org/10.1016/s0378-1119(01)00814-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008652741
348 rdf:type schema:CreativeWork
349 https://doi.org/10.1038/sj.emboj.7601748 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051024802
350 rdf:type schema:CreativeWork
351 https://doi.org/10.1042/bj20081386 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022066033
352 rdf:type schema:CreativeWork
353 https://doi.org/10.1042/ebc20170099 schema:sameAs https://app.dimensions.ai/details/publication/pub.1105733444
354 rdf:type schema:CreativeWork
355 https://doi.org/10.1056/nejm199910213411706 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010029066
356 rdf:type schema:CreativeWork
357 https://doi.org/10.1056/nejmoa0908355 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047589742
358 rdf:type schema:CreativeWork
359 https://doi.org/10.1073/pnas.0803790105 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038141563
360 rdf:type schema:CreativeWork
361 https://doi.org/10.1073/pnas.1113987109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022038590
362 rdf:type schema:CreativeWork
363 https://doi.org/10.1073/pnas.1704723114 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092338581
364 rdf:type schema:CreativeWork
365 https://doi.org/10.1074/jbc.m109.077271 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014804901
366 rdf:type schema:CreativeWork
367 https://doi.org/10.1074/jbc.m111.327866 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044310810
368 rdf:type schema:CreativeWork
369 https://doi.org/10.1074/jbc.m114.550574 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039487113
370 rdf:type schema:CreativeWork
371 https://doi.org/10.1074/jbc.m707543200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009089556
372 rdf:type schema:CreativeWork
373 https://doi.org/10.1074/jbc.m803432200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023681497
374 rdf:type schema:CreativeWork
375 https://doi.org/10.1074/jbc.m808518200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017483501
376 rdf:type schema:CreativeWork
377 https://doi.org/10.1086/512202 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058788306
378 rdf:type schema:CreativeWork
379 https://doi.org/10.1089/ars.2011.4123 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052291535
380 rdf:type schema:CreativeWork
381 https://doi.org/10.1089/ars.2013.5482 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059232235
382 rdf:type schema:CreativeWork
383 https://doi.org/10.1093/cvr/cvs111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011456924
384 rdf:type schema:CreativeWork
385 https://doi.org/10.1093/cvr/cvt080 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038705752
386 rdf:type schema:CreativeWork
387 https://doi.org/10.1093/cvr/cvv183 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010188757
388 rdf:type schema:CreativeWork
389 https://doi.org/10.1093/cvr/cvw176 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059489064
390 rdf:type schema:CreativeWork
391 https://doi.org/10.1093/eurheartj/ehw333 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059577077
392 rdf:type schema:CreativeWork
393 https://doi.org/10.1093/gbe/evu208 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032510922
394 rdf:type schema:CreativeWork
395 https://doi.org/10.1093/hmg/ddx333 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091346528
396 rdf:type schema:CreativeWork
397 https://doi.org/10.1097/fjc.0b013e31820eb8f6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035083620
398 rdf:type schema:CreativeWork
399 https://doi.org/10.1111/1440-1681.12768 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085198584
400 rdf:type schema:CreativeWork
401 https://doi.org/10.1111/cns.12273 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027088029
402 rdf:type schema:CreativeWork
403 https://doi.org/10.1111/cns.12326 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029552390
404 rdf:type schema:CreativeWork
405 https://doi.org/10.1111/j.1540-8175.2011.01532.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1025826556
406 rdf:type schema:CreativeWork
407 https://doi.org/10.1111/jpi.12193 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003786983
408 rdf:type schema:CreativeWork
409 https://doi.org/10.1113/jp271301 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017083826
410 rdf:type schema:CreativeWork
411 https://doi.org/10.1136/jmedgenet-2011-100340 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022141185
412 rdf:type schema:CreativeWork
413 https://doi.org/10.1136/jmedgenet-2012-101159 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022979113
414 rdf:type schema:CreativeWork
415 https://doi.org/10.1146/annurev-physiol-021909-135929 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025742554
416 rdf:type schema:CreativeWork
417 https://doi.org/10.1146/annurev.pharmtox.47.120505.105110 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030396639
418 rdf:type schema:CreativeWork
419 https://doi.org/10.1152/ajpheart.00027.2014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052582908
420 rdf:type schema:CreativeWork
421 https://doi.org/10.1152/ajpheart.00751.2015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063194453
422 rdf:type schema:CreativeWork
423 https://doi.org/10.1152/japplphysiol.00670.2017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1092419545
424 rdf:type schema:CreativeWork
425 https://doi.org/10.1152/physiol.00043.2010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046373333
426 rdf:type schema:CreativeWork
427 https://doi.org/10.1155/2016/1067801 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021534513
428 rdf:type schema:CreativeWork
429 https://doi.org/10.1155/2016/9152732 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012518705
430 rdf:type schema:CreativeWork
431 https://doi.org/10.1161/01.res.0000109416.56608.64 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022071880
432 rdf:type schema:CreativeWork
433 https://doi.org/10.1161/01.res.88.5.529 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023852317
434 rdf:type schema:CreativeWork
435 https://doi.org/10.1161/circheartfailure.113.000406 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014659467
436 rdf:type schema:CreativeWork
437 https://doi.org/10.1161/circheartfailure.115.002206 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079221508
438 rdf:type schema:CreativeWork
439 https://doi.org/10.1161/circheartfailure.117.004389 schema:sameAs https://app.dimensions.ai/details/publication/pub.1099767945
440 rdf:type schema:CreativeWork
441 https://doi.org/10.1161/circresaha.111.243097 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013665884
442 rdf:type schema:CreativeWork
443 https://doi.org/10.1161/circulationaha.116.026099 schema:sameAs https://app.dimensions.ai/details/publication/pub.1099768012
444 rdf:type schema:CreativeWork
445 https://doi.org/10.1161/circulationaha.117.032626 schema:sameAs https://app.dimensions.ai/details/publication/pub.1104168163
446 rdf:type schema:CreativeWork
447 https://doi.org/10.1161/hypertensionaha.111.179457 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052216905
448 rdf:type schema:CreativeWork
449 https://doi.org/10.1161/hypertensionaha.117.10787 schema:sameAs https://app.dimensions.ai/details/publication/pub.1103523752
450 rdf:type schema:CreativeWork
451 https://doi.org/10.1161/jaha.115.002701 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048736790
452 rdf:type schema:CreativeWork
453 https://doi.org/10.1161/jaha.115.003118 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042890082
454 rdf:type schema:CreativeWork
455 https://doi.org/10.1172/jci39162 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025606389
456 rdf:type schema:CreativeWork
457 https://doi.org/10.1177/1074248413515750 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029186250
458 rdf:type schema:CreativeWork
459 https://doi.org/10.1371/journal.pone.0016288 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024361177
460 rdf:type schema:CreativeWork
461 https://doi.org/10.1371/journal.pone.0094157 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019958651
462 rdf:type schema:CreativeWork
463 https://doi.org/10.1530/eje-10-0995 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053005724
464 rdf:type schema:CreativeWork
465 https://doi.org/10.18632/oncotarget.13429 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022599825
466 rdf:type schema:CreativeWork
467 https://doi.org/10.21037/atm.2018.06.21 schema:sameAs https://app.dimensions.ai/details/publication/pub.1105247194
468 rdf:type schema:CreativeWork
469 https://doi.org/10.2174/1389450116666151019095903 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069181605
470 rdf:type schema:CreativeWork
471 https://doi.org/10.2174/1570159x13666150703154541 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069196057
472 rdf:type schema:CreativeWork
473 https://doi.org/10.2337/db11-1653 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010891460
474 rdf:type schema:CreativeWork
475 https://doi.org/10.3109/10715762.2010.509398 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033053676
476 rdf:type schema:CreativeWork
477 https://doi.org/10.3389/fcvm.2016.00038 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046107521
478 rdf:type schema:CreativeWork
479 https://doi.org/10.3390/ijms12107199 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033596052
480 rdf:type schema:CreativeWork
481 https://doi.org/10.3390/ijms161025234 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013984724
482 rdf:type schema:CreativeWork
483 https://doi.org/10.3967/bes2017.037 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085444834
484 rdf:type schema:CreativeWork
485 https://doi.org/10.4239/wjd.v6.i13.1246 schema:sameAs https://app.dimensions.ai/details/publication/pub.1072397568
486 rdf:type schema:CreativeWork
487 https://doi.org/10.4330/wjc.v6.i10.1091 schema:sameAs https://app.dimensions.ai/details/publication/pub.1072525238
488 rdf:type schema:CreativeWork
489 https://www.grid.ac/institutes/grid.419543.e schema:alternateName Istituto Neurologico Mediterraneo
490 schema:name Department of Angiocardioneurology, IRCCS Neuromed, Località Camerelle, 86077, Pozzilli, IS, Italy
491 rdf:type schema:Organization
492 https://www.grid.ac/institutes/grid.7841.a schema:alternateName Sapienza University of Rome
493 schema:name Department of Angiocardioneurology, IRCCS Neuromed, Località Camerelle, 86077, Pozzilli, IS, Italy
494 Department of Clinical and Molecular Medicine, School of Medicine and Psychology, Sapienza University of Rome, Ospedale S. Andrea, Rome, Italy
495 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...