Thromboembolieprophylaxe und überbrückende Antikoagulation View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2010-08-07

AUTHORS

J. Deutsch, H. Haubelt, P. Hellstern, K.-W. Delank

ABSTRACT

Various interdisciplinary guidelines recommend that in-patients at risk of venous thromboembolism should receive pharmacologic prophylaxis. Among the anticoagulants low-molecular-weight heparins (LMWH) and fondaparinux can be considered the medications of choice because of the favorable pharmacokinetic properties when compared with unfractionated heparin. Treatment with vitamin K antagonists has to be interrupted in patients undergoing major surgery or invasive procedures. Oral anticoagulation has to be temporarily replaced by short-acting anticoagulants such as LMWH in order to prevent thromboembolic complications (anticoagulation bridging). Although LMWHs have not been approved for this clinical setting their efficacy and safety has been demonstrated in several recent studies. Detailed recommendations for prophylaxis of venous thromboembolism in otorhinolaryngology are lacking although numerous surgical procedures are considered to be associated with a significant risk of thromboembolism. A strategy for pharmacologic prophylaxis of venous thromboembolism and anticoagulation bridging in otorhinolaryngology is proposed. More... »

PAGES

770-777

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00106-010-2138-2

DOI

http://dx.doi.org/10.1007/s00106-010-2138-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1046152407

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/20694545


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