Ekkrines Adenokarzinom bei einer Patientin mit familiärem Mammakarzinom View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2008-11

AUTHORS

M. Wosnitza, A. Rübben, N. Pallua, M. Megahed

ABSTRACT

A 67-year-old patient developed a subcutaneous, non-tender nodule in her left groin over a period of about seven years. The patient underwent surgery and 4 procedures were required to obtain complete excision. The histopathologic findings showed eccrine adenocarcinoma, a member of the heterogeneous group of sweat gland tumors which occur primarily in adults with a peak of 50-60 years of age. Sweat gland carcinomas are extremely rare neoplasms of the skin and exhibit a slow growth rate with a rather high local recurrence rate. The tumor has a disposition to metastasize and shows a poor response rate to adjuvant therapy regimens. Therefore wide, deep surgical excision with an excision margin of 2-3 cm is the treatment of choice. Nevertheless there are some case reports on successful therapy of a metastasized sweat gland carcinoma with 5-fluorouracil and tamoxifen. Here further studies are needed to achieve a better survival rate for patients with metastatic disease. More... »

PAGES

879-883

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00105-008-1652-6

DOI

http://dx.doi.org/10.1007/s00105-008-1652-6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1046493620

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/18931983


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