Ontology type: schema:ScholarlyArticle
2008-07
AUTHORSH. Ott, M. Wosnitza, H.F. Merk
ABSTRACTIn vivo-methods used for clinical follow-up control during specific immunotherapy (SIT) are associated with the risk of potentially severe reactions. As a safe diagnostic alternative, several in vitro-methods are currently available permitting the evaluation of immunomodulatory SIT effects. The basophil activation test, the lymphocyte transformation test and fluorescence immunoassays detecting allergen-specific IgG- and IgG4-antibodies have been utilized for this purpose. However, a reliable correlation of an immunological follow-up parameter with clinical efficacy of SIT has not been established. Therefore, further controlled studies are needed to evaluate the clinical usefulness of the described in vitro-techniques. In the future, a combination of different diagnostic methods defining sequential immunological modifications could lead to the identification of an in vitro profile characteristic of a successful SIT. More... »
PAGES551-556
http://scigraph.springernature.com/pub.10.1007/s00105-008-1492-4
DOIhttp://dx.doi.org/10.1007/s00105-008-1492-4
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1012522706
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/18553185
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1107",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Immunology",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Desensitization, Immunologic",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Hypersensitivity",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Immunosuppressive Agents",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Universit\u00e4tsklinikum Aachen",
"id": "https://www.grid.ac/institutes/grid.412301.5",
"name": [
"Klinik f\u00fcr Dermatologie und Allergologie, Universit\u00e4tsklinikum Aachen, Pauwelsstra\u00dfe 30, 52074, Aachen, Deutschland"
],
"type": "Organization"
},
"familyName": "Ott",
"givenName": "H.",
"id": "sg:person.01174547015.43",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01174547015.43"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Universit\u00e4tsklinikum Aachen",
"id": "https://www.grid.ac/institutes/grid.412301.5",
"name": [
"Klinik f\u00fcr Dermatologie und Allergologie, Universit\u00e4tsklinikum Aachen, Pauwelsstra\u00dfe 30, 52074, Aachen, Deutschland"
],
"type": "Organization"
},
"familyName": "Wosnitza",
"givenName": "M.",
"id": "sg:person.0760615601.64",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0760615601.64"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Universit\u00e4tsklinikum Aachen",
"id": "https://www.grid.ac/institutes/grid.412301.5",
"name": [
"Klinik f\u00fcr Dermatologie und Allergologie, Universit\u00e4tsklinikum Aachen, Pauwelsstra\u00dfe 30, 52074, Aachen, Deutschland"
],
"type": "Organization"
},
"familyName": "Merk",
"givenName": "H.F.",
"id": "sg:person.01035371551.10",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01035371551.10"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1007/s00105-006-1167-y",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001256175",
"https://doi.org/10.1007/s00105-006-1167-y"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00105-006-1167-y",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001256175",
"https://doi.org/10.1007/s00105-006-1167-y"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.vaccine.2006.08.040",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002056611"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1365-2222.2004.01899.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002648208"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1046/j.1365-2222.1998.00222.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1005114291"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1365-2222.1993.tb01791.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010988555"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/cyto.b.20142",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011492744"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1398-9995.2004.00624.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015183571"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1398-9995.2007.01451.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016754225"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nri1934",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018053048",
"https://doi.org/10.1038/nri1934"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nri1934",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018053048",
"https://doi.org/10.1038/nri1934"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1365-2222.1978.tb03221.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018400095"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/cyto.b.20419",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019677498"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1365-2222.1976.tb01901.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021279883"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jaci.2007.01.022",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021818467"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.4049/jimmunol.172.5.3252",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026732733"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jim.2006.09.004",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033548015"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1056/nejm197807272990401",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033841716"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1398-9995.1984.tb01965.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034587651"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1399-3038.2006.00442.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034953053"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1172/jci25575",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035696910"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1365-2222.2004.01949.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035949733"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1365-2222.2006.02487.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037332598"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/01.all.0000136753.35948.c0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037348692"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/01.all.0000136753.35948.c0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037348692"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1097/01.all.0000136753.35948.c0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037348692"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1084/jem.62.6.733",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038168099"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1378/chest.06-2434",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039113775"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1046/j.1365-2222.2001.01027.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040304880"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1046/j.1365-2222.2003.01699.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040877549"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1398-9995.2006.01175.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040936513"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0140-6736(00)78276-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043785025"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0140-6736(00)78276-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043785025"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1398-9995.2004.00400.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046374647"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1046/j.1365-3083.1997.d01-87.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046778457"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1046/j.1365-3083.1997.d01-87.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046778457"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1398-9995.1996.tb04596.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1047218798"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1067/mai.2001.114708",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1051290254"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1398-9995.2008.01748.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1051416956"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jaci.2008.01.072",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052186398"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.jaci.2008.01.072",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052186398"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1077179108",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1077473380",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1077478245",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1083158673",
"type": "CreativeWork"
}
],
"datePublished": "2008-07",
"datePublishedReg": "2008-07-01",
"description": "In vivo-methods used for clinical follow-up control during specific immunotherapy (SIT) are associated with the risk of potentially severe reactions. As a safe diagnostic alternative, several in vitro-methods are currently available permitting the evaluation of immunomodulatory SIT effects. The basophil activation test, the lymphocyte transformation test and fluorescence immunoassays detecting allergen-specific IgG- and IgG4-antibodies have been utilized for this purpose. However, a reliable correlation of an immunological follow-up parameter with clinical efficacy of SIT has not been established. Therefore, further controlled studies are needed to evaluate the clinical usefulness of the described in vitro-techniques. In the future, a combination of different diagnostic methods defining sequential immunological modifications could lead to the identification of an in vitro profile characteristic of a successful SIT.",
"genre": "research_article",
"id": "sg:pub.10.1007/s00105-008-1492-4",
"inLanguage": [
"de"
],
"isAccessibleForFree": false,
"isPartOf": [
{
"id": "sg:journal.1327382",
"issn": [
"0017-8470",
"1432-1173"
],
"name": "Der Hautarzt",
"type": "Periodical"
},
{
"issueNumber": "7",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "59"
}
],
"name": "Immunologische Verlaufsparameter unter spezifischer Immuntherapie",
"pagination": "551-556",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"3ba92a90c1d1837f3ae991af69992833d45b41d89fbe8030139ed9de45b0e072"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"18553185"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"0372755"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/s00105-008-1492-4"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1012522706"
]
}
],
"sameAs": [
"https://doi.org/10.1007/s00105-008-1492-4",
"https://app.dimensions.ai/details/publication/pub.1012522706"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-11T14:26",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000373_0000000373/records_13071_00000000.jsonl",
"type": "ScholarlyArticle",
"url": "http://link.springer.com/10.1007/s00105-008-1492-4"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00105-008-1492-4'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00105-008-1492-4'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00105-008-1492-4'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00105-008-1492-4'
This table displays all metadata directly associated to this object as RDF triples.
211 TRIPLES
21 PREDICATES
71 URIs
25 LITERALS
13 BLANK NODES