Kombinierte Nieren-Pankreas-Transplantation View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2007-10

AUTHORS

M. Schäffer, V. Bartmann, A. Wunsch, T. Traska, P. Schenker, S. Michalski, R. Viebahn

ABSTRACT

BACKGROUND: Differences in graft survival due to gender have been reported after transplantation of the kidney, liver, and heart. However, little is known about the role of donor and recipient gender in simultaneous pancreas-kidney transplantation. METHODS: Single-centre analysis was performed of first simultaneous pancreas-kidney transplantations performed between 1994 and 2005 at the Bochum Transplant Center in Germany (n=218). RESULTS: Recipients of female donor organs exhibited acute organ rejections earlier and more frequently (P<0.05). Male recipients of organs from male donors had a lower risk of acute rejection than recipients of female donor organs (P<0.05). In addition to female donor gender, higher donor age and early kidney dysfunction were risk factors for perioperative rejection (P<0.05). Long-term kidney and pancreas function was best in male-donor-to-female-recipient transplants over the time periods of 7 and 3 years, respectively (P<0.05). Risk factors of long-term organ failure were: the need of revision laparotomy, organ rejection, and early postoperative organ dysfunction (P<0.05). CONCLUSION: This is the first report of graft function after simultaneous pancreas-kidney transplantation looking specifically at gender differences with respect to donor and recipient. There was an increased risk of organ rejection of female donor organs. More... »

PAGES

928-935

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00104-007-1362-0

DOI

http://dx.doi.org/10.1007/s00104-007-1362-0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1049861228

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/17565475


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N-Triples is a line-based linked data format ideal for batch operations.

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Turtle is a human-readable linked data format.

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RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00104-007-1362-0'


 

This table displays all metadata directly associated to this object as RDF triples.

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