Integrated Biomarkers in Cardiomyopathies View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2007-09

AUTHORS

Jeanette Schulz-Menger, Bernhard Maisch, Hassan Abdel-Aty, Sabine Pankuweit

ABSTRACT

In an integrated approach, the authors examine the most efficient combination of noninvasive and invasive biochemical, immunologic, functional, molecular, imaging and biopsy-derived biomarkers for their applicability in the diagnosis of cardiomyopathies in general and dilated cardiomyopathy (DCM) in particular. A careful selection out of the cascade of available biomarkers will allow, in individual patients, to diagnose certain conditions of cardiomyopathies without endomyocardial biopsy, e.g., borreliosis, rickettsiosis, HIV cardiomyopathy. Viral persistence in DCM associated with inflammation will need both noninvasive (echocardiography, cardiovascular magnetic resonance) and invasive biomarkers (polymerase chain reaction for viral persistence or their exclusion in case of autoreactive myocarditis and quantitative immunohistology, both from endomyocardial biopsy). More... »

PAGES

458-472

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00059-007-3046-4

DOI

http://dx.doi.org/10.1007/s00059-007-3046-4

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1026717583

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/17882371


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