Ontology type: schema:ScholarlyArticle
2012-09-06
AUTHORSAkhilesh K. Yadav, N. Manika, Guru D. Bagchi, Madan M. Gupta
ABSTRACTA reverse-phase liquid chromatographic method has been established for analysis of oroxylin A, chrysin, baicalein, and hispidulin in the roots of Oroxylum indicum (Bignoneaceae). Under the optimized conditions, well-resolved separation of pure compounds with significantly different Rt values was achieved on chromolith C18 column (100 mm × 4.6 mm, 10 μm) using isocratic elution of acetonitrile and water (0.1 % trifluoroacetic acid); with acceptable validation results such as linearity, sensitivity, and recovery in terms of %RSD. The calibration curves were linear in the concentration range of 200–500 ng ml−1. Method was validated as per ICH guidelines. The developed reproducible and robust method may be applied for the quality assays of O. indicum and phytopreparations. More... »
PAGES2222-2227
http://scigraph.springernature.com/pub.10.1007/s00044-012-0214-8
DOIhttp://dx.doi.org/10.1007/s00044-012-0214-8
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