Liposarcoma: molecular targets and therapeutic implications View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2016-10

AUTHORS

Kate Lynn J. Bill, Lucia Casadei, Bethany C. Prudner, Hans Iwenofu, Anne M. Strohecker, Raphael E. Pollock

ABSTRACT

Liposarcoma (LPS) is the most common soft tissue sarcoma and accounts for approximately 20 % of all adult sarcomas. Current treatment modalities (surgery, chemotherapy, and radiotherapy) all have limitations; therefore, molecularly driven studies are needed to improve the identification and increased understanding of genetic and epigenetic deregulations in LPS if we are to successfully target specific tumorigenic drivers. It can be anticipated that such biology-driven therapeutics will improve treatments by selectively deleting cancer cells while sparing normal tissues. This review will focus on several therapeutically actionable molecular markers identified in well-differentiated LPS and dedifferentiated LPS, highlighting their potential clinical applicability. More... »

PAGES

3711-3718

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00018-016-2266-2

DOI

http://dx.doi.org/10.1007/s00018-016-2266-2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1005953719

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27173057


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Biomarkers, Tumor", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Disease Progression", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Liposarcoma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "MicroRNAs", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Targeted Therapy", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "The Ohio State University", 
          "id": "https://www.grid.ac/institutes/grid.261331.4", 
          "name": [
            "The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA", 
            "Division of Surgical Oncology, Department of Surgery, Wexner Medical Center, The Ohio State University, 410W 10th Ave., 43210, Columbus, OH, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bill", 
        "givenName": "Kate Lynn J.", 
        "id": "sg:person.01264315171.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01264315171.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The Ohio State University", 
          "id": "https://www.grid.ac/institutes/grid.261331.4", 
          "name": [
            "The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA", 
            "Division of Surgical Oncology, Department of Surgery, Wexner Medical Center, The Ohio State University, 410W 10th Ave., 43210, Columbus, OH, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Casadei", 
        "givenName": "Lucia", 
        "id": "sg:person.01202427250.67", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01202427250.67"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The Ohio State University", 
          "id": "https://www.grid.ac/institutes/grid.261331.4", 
          "name": [
            "The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA", 
            "Division of Surgical Oncology, Department of Surgery, Wexner Medical Center, The Ohio State University, 410W 10th Ave., 43210, Columbus, OH, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Prudner", 
        "givenName": "Bethany C.", 
        "id": "sg:person.01007034755.79", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01007034755.79"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The Ohio State University", 
          "id": "https://www.grid.ac/institutes/grid.261331.4", 
          "name": [
            "The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA", 
            "Department of Pathology, The Ohio State University, Columbus, OH, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Iwenofu", 
        "givenName": "Hans", 
        "id": "sg:person.0625462203.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625462203.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The Ohio State University", 
          "id": "https://www.grid.ac/institutes/grid.261331.4", 
          "name": [
            "The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA", 
            "Division of Surgical Oncology, Department of Surgery, Wexner Medical Center, The Ohio State University, 410W 10th Ave., 43210, Columbus, OH, USA", 
            "Department of Molecular Virology, Immunology, and Medical Genetics, The Ohio State University, Columbus, OH, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Strohecker", 
        "givenName": "Anne M.", 
        "id": "sg:person.0761236170.82", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0761236170.82"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The Ohio State University", 
          "id": "https://www.grid.ac/institutes/grid.261331.4", 
          "name": [
            "The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA", 
            "Division of Surgical Oncology, Department of Surgery, Wexner Medical Center, The Ohio State University, 410W 10th Ave., 43210, Columbus, OH, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pollock", 
        "givenName": "Raphael E.", 
        "id": "sg:person.07756432137.83", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07756432137.83"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/978-3-0348-9070-0_6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000059429", 
          "https://doi.org/10.1007/978-3-0348-9070-0_6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-0348-9070-0_6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000059429", 
          "https://doi.org/10.1007/978-3-0348-9070-0_6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-011-1794-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000475499", 
          "https://doi.org/10.1245/s10434-011-1794-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncb1596", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001718862", 
          "https://doi.org/10.1038/ncb1596"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/02841868309134353", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003663816"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.brs.0000251863.76595.a2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004763745"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.brs.0000251863.76595.a2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004763745"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrclinonc.2014.5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004935950", 
          "https://doi.org/10.1038/nrclinonc.2014.5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000478-197912000-00004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005237630"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000478-197912000-00004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005237630"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-007-9805-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005324061", 
          "https://doi.org/10.1245/s10434-007-9805-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/2159-8290.cd-11-0181", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006466734"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2015.63.3651", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006803515"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1535-7163.mct-14-0387", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007772039"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jor.22827", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008319491"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/labinvest.2010.185", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008419137", 
          "https://doi.org/10.1038/labinvest.2010.185"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.85.7.2215", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009128451"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3389/fgene.2013.00214", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010204225"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/oncsis.2013.10", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010887930", 
          "https://doi.org/10.1038/oncsis.2013.10"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/adpa.2000.8133", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010986560"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0165-4608(96)00436-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012233162"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/pap.0000000000000101", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013840161"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/pap.0000000000000101", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013840161"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/pap.0000000000000101", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013840161"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2353/ajpath.2008.070284", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014083519"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/labinvest.2010.53", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014675971", 
          "https://doi.org/10.1038/labinvest.2010.53"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.23150", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015592061"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2005.04.754", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017153509"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2008.18.0802", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017397932"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-11-0890", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018835959"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1096-9896(199806)185:2<188::aid-path53>3.0.co;2-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019205143"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1096-9896(199806)185:2<188::aid-path53>3.0.co;2-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019205143"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1096-9896(200004)190:5<531::aid-path579>3.0.co;2-w", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019280975"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1210836", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019311059", 
          "https://doi.org/10.1038/sj.onc.1210836"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/cco.0b013e32834796e6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019730037"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/cco.0b013e32834796e6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019730037"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/coh.0b013e32833ed177", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019907000"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/coh.0b013e32833ed177", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019907000"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/coh.0b013e32833ed177", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019907000"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cancergencyto.2004.08.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020596531"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/modpathol.3800326", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020628868", 
          "https://doi.org/10.1038/modpathol.3800326"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/modpathol.3800326", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020628868", 
          "https://doi.org/10.1038/modpathol.3800326"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2010.28.5635", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021222916"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000478-198703000-00001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021594770"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000478-198703000-00001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021594770"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-11-0193", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021904198"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/gcc.20906", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024119322"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.pharmthera.2012.08.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024872275"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbrc.2003.12.203", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026079079"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/labinvest.2015.62", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026771422", 
          "https://doi.org/10.1038/labinvest.2015.62"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1470-2045(04)01709-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027590690"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1586/14737140.2014.869173", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027674042"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1209414109", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028210372"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbrc.2010.08.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029173434"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1756-9966-31-38", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029533420", 
          "https://doi.org/10.1186/1756-9966-31-38"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijrobp.2008.04.044", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029900120"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijrobp.2006.09.025", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030092950"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1245/s10434-014-3643-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031185369", 
          "https://doi.org/10.1245/s10434-014-3643-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/emboj/18.1.188", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032202617"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00066-009-1873-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032253795", 
          "https://doi.org/10.1007/s00066-009-1873-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00066-009-1873-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032253795", 
          "https://doi.org/10.1007/s00066-009-1873-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ccr.2007.02.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032459379"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00066-009-2044-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034568446", 
          "https://doi.org/10.1007/s00066-009-2044-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00066-009-2044-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034568446", 
          "https://doi.org/10.1007/s00066-009-2044-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00066-009-2044-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034568446", 
          "https://doi.org/10.1007/s00066-009-2044-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00066-010-2110-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036068485", 
          "https://doi.org/10.1007/s00066-010-2110-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00066-010-2110-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036068485", 
          "https://doi.org/10.1007/s00066-010-2110-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00066-010-2095-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036447934", 
          "https://doi.org/10.1007/s00066-010-2095-4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/gcc.2870090309", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036786381"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.28657", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037053165"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/pas.0b013e3181e5dc49", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037615990"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/pas.0b013e3181e5dc49", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037615990"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/pas.0b013e3181e5dc49", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037615990"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(05)66954-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037998653"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0046-8177(97)90060-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038179190"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s12032-013-0531-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038190420", 
          "https://doi.org/10.1007/s12032-013-0531-x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jamcollsurg.2013.10.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038656420"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jor.23002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039814334"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/bjc.2015.253", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040791125", 
          "https://doi.org/10.1038/bjc.2015.253"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-08-3185", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041953362"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/gcc.21980", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042133616"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3389/fgene.2013.00142", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042400693"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2217/fon.14.90", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042530431"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-11-3027", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043301400"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/gcc.20012", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043319717"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0360-3016(02)03864-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045088465"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0360-3016(02)03864-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045088465"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ijc.28694", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045326685"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/s12943-015-0424-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048244696", 
          "https://doi.org/10.1186/s12943-015-0424-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.21933", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048692292"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/pas.0b013e3181dbf2f7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049840548"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/pas.0b013e3181dbf2f7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049840548"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/pas.0b013e3181dbf2f7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049840548"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0360-3016(99)00559-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051637003"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000478-199411000-00009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053187182"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000478-199411000-00009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053187182"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/path.2564", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053498221"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/path.2564", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053498221"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000478-199703000-00002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060122273"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000478-199703000-00002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060122273"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000478-199703000-00002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060122273"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.sla.0000086542.11899.38", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060331828"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.sla.0000086542.11899.38", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060331828"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.sla.0000086542.11899.38", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060331828"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.sla.0000086542.11899.38", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060331828"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.sla.0000086542.11899.38", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060331828"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-15-1522", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063225041"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3892/mmr.2011.426", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071520065"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074657437", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076569290", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077287869", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077346820", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082468201", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082883135", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2016-10", 
    "datePublishedReg": "2016-10-01", 
    "description": "Liposarcoma (LPS) is the most common soft tissue sarcoma and accounts for approximately 20\u00a0% of all adult sarcomas. Current treatment modalities (surgery, chemotherapy, and radiotherapy) all have limitations; therefore, molecularly driven studies are needed to improve the identification and increased understanding of genetic and epigenetic deregulations in LPS if we are to successfully target specific tumorigenic drivers. It can be anticipated that such biology-driven therapeutics will improve treatments by selectively deleting cancer cells while sparing normal tissues. This review will focus on several therapeutically actionable molecular markers identified in well-differentiated LPS and dedifferentiated LPS, highlighting their potential clinical applicability.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/s00018-016-2266-2", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2699159", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1295005", 
        "issn": [
          "1420-682X", 
          "1420-9071"
        ], 
        "name": "Cellular and Molecular Life Sciences", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "19", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "73"
      }
    ], 
    "name": "Liposarcoma: molecular targets and therapeutic implications", 
    "pagination": "3711-3718", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "1c5c4b95eaa2fc1ea47532feffaa5b7c193107bb17ae918d2f039088441e2b53"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "27173057"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9705402"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/s00018-016-2266-2"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1005953719"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/s00018-016-2266-2", 
      "https://app.dimensions.ai/details/publication/pub.1005953719"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T19:05", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8678_00000494.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/s00018-016-2266-2"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/s00018-016-2266-2'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/s00018-016-2266-2'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/s00018-016-2266-2'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/s00018-016-2266-2'


 

This table displays all metadata directly associated to this object as RDF triples.

409 TRIPLES      21 PREDICATES      122 URIs      28 LITERALS      16 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/s00018-016-2266-2 schema:about N182c2d47978145cd9eb66ccf1f9651d1
2 N3b20b15dba424879aa4b59608e344c11
3 N4eb0f52d511446f3a567bcd9c345cd6c
4 N699d3115ff574d889b40b85ed422addf
5 Nb451673383234509a8d47038b889252d
6 Nd8ea5d9910134d0aac17cf2c66f8ad3a
7 Neee2897bd47b49ceb97652861ffd208c
8 anzsrc-for:11
9 anzsrc-for:1112
10 schema:author N5854779902bc4435acb262e498dd8942
11 schema:citation sg:pub.10.1007/978-3-0348-9070-0_6
12 sg:pub.10.1007/s00066-009-1873-3
13 sg:pub.10.1007/s00066-009-2044-2
14 sg:pub.10.1007/s00066-010-2095-4
15 sg:pub.10.1007/s00066-010-2110-9
16 sg:pub.10.1007/s12032-013-0531-x
17 sg:pub.10.1038/bjc.2015.253
18 sg:pub.10.1038/labinvest.2010.185
19 sg:pub.10.1038/labinvest.2010.53
20 sg:pub.10.1038/labinvest.2015.62
21 sg:pub.10.1038/modpathol.3800326
22 sg:pub.10.1038/ncb1596
23 sg:pub.10.1038/nrclinonc.2014.5
24 sg:pub.10.1038/oncsis.2013.10
25 sg:pub.10.1038/sj.onc.1210836
26 sg:pub.10.1186/1756-9966-31-38
27 sg:pub.10.1186/s12943-015-0424-z
28 sg:pub.10.1245/s10434-007-9805-x
29 sg:pub.10.1245/s10434-011-1794-0
30 sg:pub.10.1245/s10434-014-3643-4
31 https://app.dimensions.ai/details/publication/pub.1074657437
32 https://app.dimensions.ai/details/publication/pub.1076569290
33 https://app.dimensions.ai/details/publication/pub.1077287869
34 https://app.dimensions.ai/details/publication/pub.1077346820
35 https://app.dimensions.ai/details/publication/pub.1082468201
36 https://app.dimensions.ai/details/publication/pub.1082883135
37 https://doi.org/10.1002/(sici)1096-9896(199806)185:2<188::aid-path53>3.0.co;2-2
38 https://doi.org/10.1002/(sici)1096-9896(200004)190:5<531::aid-path579>3.0.co;2-w
39 https://doi.org/10.1002/cncr.21933
40 https://doi.org/10.1002/cncr.23150
41 https://doi.org/10.1002/cncr.28657
42 https://doi.org/10.1002/gcc.20012
43 https://doi.org/10.1002/gcc.20906
44 https://doi.org/10.1002/gcc.21980
45 https://doi.org/10.1002/gcc.2870090309
46 https://doi.org/10.1002/ijc.28694
47 https://doi.org/10.1002/jor.22827
48 https://doi.org/10.1002/jor.23002
49 https://doi.org/10.1002/path.2564
50 https://doi.org/10.1016/j.bbrc.2003.12.203
51 https://doi.org/10.1016/j.bbrc.2010.08.015
52 https://doi.org/10.1016/j.cancergencyto.2004.08.005
53 https://doi.org/10.1016/j.ccr.2007.02.007
54 https://doi.org/10.1016/j.ijrobp.2006.09.025
55 https://doi.org/10.1016/j.ijrobp.2008.04.044
56 https://doi.org/10.1016/j.jamcollsurg.2013.10.009
57 https://doi.org/10.1016/j.pharmthera.2012.08.003
58 https://doi.org/10.1016/s0046-8177(97)90060-5
59 https://doi.org/10.1016/s0140-6736(05)66954-1
60 https://doi.org/10.1016/s0165-4608(96)00436-0
61 https://doi.org/10.1016/s0360-3016(02)03864-6
62 https://doi.org/10.1016/s0360-3016(99)00559-3
63 https://doi.org/10.1016/s1470-2045(04)01709-7
64 https://doi.org/10.1053/adpa.2000.8133
65 https://doi.org/10.1073/pnas.1209414109
66 https://doi.org/10.1073/pnas.85.7.2215
67 https://doi.org/10.1093/emboj/18.1.188
68 https://doi.org/10.1097/00000478-197912000-00004
69 https://doi.org/10.1097/00000478-198703000-00001
70 https://doi.org/10.1097/00000478-199411000-00009
71 https://doi.org/10.1097/00000478-199703000-00002
72 https://doi.org/10.1097/01.brs.0000251863.76595.a2
73 https://doi.org/10.1097/01.sla.0000086542.11899.38
74 https://doi.org/10.1097/cco.0b013e32834796e6
75 https://doi.org/10.1097/coh.0b013e32833ed177
76 https://doi.org/10.1097/pap.0000000000000101
77 https://doi.org/10.1097/pas.0b013e3181dbf2f7
78 https://doi.org/10.1097/pas.0b013e3181e5dc49
79 https://doi.org/10.1158/0008-5472.can-11-0890
80 https://doi.org/10.1158/0008-5472.can-11-3027
81 https://doi.org/10.1158/1078-0432.ccr-08-3185
82 https://doi.org/10.1158/1078-0432.ccr-11-0193
83 https://doi.org/10.1158/1078-0432.ccr-15-1522
84 https://doi.org/10.1158/1535-7163.mct-14-0387
85 https://doi.org/10.1158/2159-8290.cd-11-0181
86 https://doi.org/10.1200/jco.2005.04.754
87 https://doi.org/10.1200/jco.2008.18.0802
88 https://doi.org/10.1200/jco.2010.28.5635
89 https://doi.org/10.1200/jco.2015.63.3651
90 https://doi.org/10.1586/14737140.2014.869173
91 https://doi.org/10.2217/fon.14.90
92 https://doi.org/10.2353/ajpath.2008.070284
93 https://doi.org/10.3109/02841868309134353
94 https://doi.org/10.3389/fgene.2013.00142
95 https://doi.org/10.3389/fgene.2013.00214
96 https://doi.org/10.3892/mmr.2011.426
97 schema:datePublished 2016-10
98 schema:datePublishedReg 2016-10-01
99 schema:description Liposarcoma (LPS) is the most common soft tissue sarcoma and accounts for approximately 20 % of all adult sarcomas. Current treatment modalities (surgery, chemotherapy, and radiotherapy) all have limitations; therefore, molecularly driven studies are needed to improve the identification and increased understanding of genetic and epigenetic deregulations in LPS if we are to successfully target specific tumorigenic drivers. It can be anticipated that such biology-driven therapeutics will improve treatments by selectively deleting cancer cells while sparing normal tissues. This review will focus on several therapeutically actionable molecular markers identified in well-differentiated LPS and dedifferentiated LPS, highlighting their potential clinical applicability.
100 schema:genre research_article
101 schema:inLanguage en
102 schema:isAccessibleForFree false
103 schema:isPartOf N7a823d45369e441c8113da5eb726bd56
104 Nd146b482c3ad4838b3077c5a46d6d09e
105 sg:journal.1295005
106 schema:name Liposarcoma: molecular targets and therapeutic implications
107 schema:pagination 3711-3718
108 schema:productId N35cb098afc2e430ebc59dac774fe9cb6
109 N4b7f391a16c94f51b6dae7d8f4db46ab
110 N9ed37a24ced948639e2bd2878fabb3cb
111 N9ee321f67e6f4d9eb025415438dc621b
112 Nb85fb688834e4d10bb17e569aea3f28a
113 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005953719
114 https://doi.org/10.1007/s00018-016-2266-2
115 schema:sdDatePublished 2019-04-10T19:05
116 schema:sdLicense https://scigraph.springernature.com/explorer/license/
117 schema:sdPublisher N4a751f1ed6b54dc592922a4de5bd702d
118 schema:url http://link.springer.com/10.1007/s00018-016-2266-2
119 sgo:license sg:explorer/license/
120 sgo:sdDataset articles
121 rdf:type schema:ScholarlyArticle
122 N182c2d47978145cd9eb66ccf1f9651d1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Biomarkers, Tumor
124 rdf:type schema:DefinedTerm
125 N35cb098afc2e430ebc59dac774fe9cb6 schema:name doi
126 schema:value 10.1007/s00018-016-2266-2
127 rdf:type schema:PropertyValue
128 N3b20b15dba424879aa4b59608e344c11 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name MicroRNAs
130 rdf:type schema:DefinedTerm
131 N4a751f1ed6b54dc592922a4de5bd702d schema:name Springer Nature - SN SciGraph project
132 rdf:type schema:Organization
133 N4b7f391a16c94f51b6dae7d8f4db46ab schema:name pubmed_id
134 schema:value 27173057
135 rdf:type schema:PropertyValue
136 N4eb0f52d511446f3a567bcd9c345cd6c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Animals
138 rdf:type schema:DefinedTerm
139 N5854779902bc4435acb262e498dd8942 rdf:first sg:person.01264315171.21
140 rdf:rest N5e977ff2b68b4e83a8a97636438ae263
141 N5e977ff2b68b4e83a8a97636438ae263 rdf:first sg:person.01202427250.67
142 rdf:rest Naa513d7ba8034a4fbdddfb9503d6de71
143 N699d3115ff574d889b40b85ed422addf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Liposarcoma
145 rdf:type schema:DefinedTerm
146 N7a823d45369e441c8113da5eb726bd56 schema:volumeNumber 73
147 rdf:type schema:PublicationVolume
148 N9ed37a24ced948639e2bd2878fabb3cb schema:name dimensions_id
149 schema:value pub.1005953719
150 rdf:type schema:PropertyValue
151 N9ee321f67e6f4d9eb025415438dc621b schema:name nlm_unique_id
152 schema:value 9705402
153 rdf:type schema:PropertyValue
154 Na1636f25319745aeb33f5088cea5bebe rdf:first sg:person.0761236170.82
155 rdf:rest Nc2db6d1d060145f59609845034b2cd0f
156 Naa513d7ba8034a4fbdddfb9503d6de71 rdf:first sg:person.01007034755.79
157 rdf:rest Ne45505c870e94e13af6e6cf5390cf564
158 Nb451673383234509a8d47038b889252d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name Humans
160 rdf:type schema:DefinedTerm
161 Nb85fb688834e4d10bb17e569aea3f28a schema:name readcube_id
162 schema:value 1c5c4b95eaa2fc1ea47532feffaa5b7c193107bb17ae918d2f039088441e2b53
163 rdf:type schema:PropertyValue
164 Nc2db6d1d060145f59609845034b2cd0f rdf:first sg:person.07756432137.83
165 rdf:rest rdf:nil
166 Nd146b482c3ad4838b3077c5a46d6d09e schema:issueNumber 19
167 rdf:type schema:PublicationIssue
168 Nd8ea5d9910134d0aac17cf2c66f8ad3a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
169 schema:name Disease Progression
170 rdf:type schema:DefinedTerm
171 Ne45505c870e94e13af6e6cf5390cf564 rdf:first sg:person.0625462203.01
172 rdf:rest Na1636f25319745aeb33f5088cea5bebe
173 Neee2897bd47b49ceb97652861ffd208c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
174 schema:name Molecular Targeted Therapy
175 rdf:type schema:DefinedTerm
176 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
177 schema:name Medical and Health Sciences
178 rdf:type schema:DefinedTerm
179 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
180 schema:name Oncology and Carcinogenesis
181 rdf:type schema:DefinedTerm
182 sg:grant.2699159 http://pending.schema.org/fundedItem sg:pub.10.1007/s00018-016-2266-2
183 rdf:type schema:MonetaryGrant
184 sg:journal.1295005 schema:issn 1420-682X
185 1420-9071
186 schema:name Cellular and Molecular Life Sciences
187 rdf:type schema:Periodical
188 sg:person.01007034755.79 schema:affiliation https://www.grid.ac/institutes/grid.261331.4
189 schema:familyName Prudner
190 schema:givenName Bethany C.
191 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01007034755.79
192 rdf:type schema:Person
193 sg:person.01202427250.67 schema:affiliation https://www.grid.ac/institutes/grid.261331.4
194 schema:familyName Casadei
195 schema:givenName Lucia
196 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01202427250.67
197 rdf:type schema:Person
198 sg:person.01264315171.21 schema:affiliation https://www.grid.ac/institutes/grid.261331.4
199 schema:familyName Bill
200 schema:givenName Kate Lynn J.
201 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01264315171.21
202 rdf:type schema:Person
203 sg:person.0625462203.01 schema:affiliation https://www.grid.ac/institutes/grid.261331.4
204 schema:familyName Iwenofu
205 schema:givenName Hans
206 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625462203.01
207 rdf:type schema:Person
208 sg:person.0761236170.82 schema:affiliation https://www.grid.ac/institutes/grid.261331.4
209 schema:familyName Strohecker
210 schema:givenName Anne M.
211 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0761236170.82
212 rdf:type schema:Person
213 sg:person.07756432137.83 schema:affiliation https://www.grid.ac/institutes/grid.261331.4
214 schema:familyName Pollock
215 schema:givenName Raphael E.
216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07756432137.83
217 rdf:type schema:Person
218 sg:pub.10.1007/978-3-0348-9070-0_6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000059429
219 https://doi.org/10.1007/978-3-0348-9070-0_6
220 rdf:type schema:CreativeWork
221 sg:pub.10.1007/s00066-009-1873-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032253795
222 https://doi.org/10.1007/s00066-009-1873-3
223 rdf:type schema:CreativeWork
224 sg:pub.10.1007/s00066-009-2044-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034568446
225 https://doi.org/10.1007/s00066-009-2044-2
226 rdf:type schema:CreativeWork
227 sg:pub.10.1007/s00066-010-2095-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036447934
228 https://doi.org/10.1007/s00066-010-2095-4
229 rdf:type schema:CreativeWork
230 sg:pub.10.1007/s00066-010-2110-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036068485
231 https://doi.org/10.1007/s00066-010-2110-9
232 rdf:type schema:CreativeWork
233 sg:pub.10.1007/s12032-013-0531-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1038190420
234 https://doi.org/10.1007/s12032-013-0531-x
235 rdf:type schema:CreativeWork
236 sg:pub.10.1038/bjc.2015.253 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040791125
237 https://doi.org/10.1038/bjc.2015.253
238 rdf:type schema:CreativeWork
239 sg:pub.10.1038/labinvest.2010.185 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008419137
240 https://doi.org/10.1038/labinvest.2010.185
241 rdf:type schema:CreativeWork
242 sg:pub.10.1038/labinvest.2010.53 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014675971
243 https://doi.org/10.1038/labinvest.2010.53
244 rdf:type schema:CreativeWork
245 sg:pub.10.1038/labinvest.2015.62 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026771422
246 https://doi.org/10.1038/labinvest.2015.62
247 rdf:type schema:CreativeWork
248 sg:pub.10.1038/modpathol.3800326 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020628868
249 https://doi.org/10.1038/modpathol.3800326
250 rdf:type schema:CreativeWork
251 sg:pub.10.1038/ncb1596 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001718862
252 https://doi.org/10.1038/ncb1596
253 rdf:type schema:CreativeWork
254 sg:pub.10.1038/nrclinonc.2014.5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004935950
255 https://doi.org/10.1038/nrclinonc.2014.5
256 rdf:type schema:CreativeWork
257 sg:pub.10.1038/oncsis.2013.10 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010887930
258 https://doi.org/10.1038/oncsis.2013.10
259 rdf:type schema:CreativeWork
260 sg:pub.10.1038/sj.onc.1210836 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019311059
261 https://doi.org/10.1038/sj.onc.1210836
262 rdf:type schema:CreativeWork
263 sg:pub.10.1186/1756-9966-31-38 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029533420
264 https://doi.org/10.1186/1756-9966-31-38
265 rdf:type schema:CreativeWork
266 sg:pub.10.1186/s12943-015-0424-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1048244696
267 https://doi.org/10.1186/s12943-015-0424-z
268 rdf:type schema:CreativeWork
269 sg:pub.10.1245/s10434-007-9805-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1005324061
270 https://doi.org/10.1245/s10434-007-9805-x
271 rdf:type schema:CreativeWork
272 sg:pub.10.1245/s10434-011-1794-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000475499
273 https://doi.org/10.1245/s10434-011-1794-0
274 rdf:type schema:CreativeWork
275 sg:pub.10.1245/s10434-014-3643-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031185369
276 https://doi.org/10.1245/s10434-014-3643-4
277 rdf:type schema:CreativeWork
278 https://app.dimensions.ai/details/publication/pub.1074657437 schema:CreativeWork
279 https://app.dimensions.ai/details/publication/pub.1076569290 schema:CreativeWork
280 https://app.dimensions.ai/details/publication/pub.1077287869 schema:CreativeWork
281 https://app.dimensions.ai/details/publication/pub.1077346820 schema:CreativeWork
282 https://app.dimensions.ai/details/publication/pub.1082468201 schema:CreativeWork
283 https://app.dimensions.ai/details/publication/pub.1082883135 schema:CreativeWork
284 https://doi.org/10.1002/(sici)1096-9896(199806)185:2<188::aid-path53>3.0.co;2-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019205143
285 rdf:type schema:CreativeWork
286 https://doi.org/10.1002/(sici)1096-9896(200004)190:5<531::aid-path579>3.0.co;2-w schema:sameAs https://app.dimensions.ai/details/publication/pub.1019280975
287 rdf:type schema:CreativeWork
288 https://doi.org/10.1002/cncr.21933 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048692292
289 rdf:type schema:CreativeWork
290 https://doi.org/10.1002/cncr.23150 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015592061
291 rdf:type schema:CreativeWork
292 https://doi.org/10.1002/cncr.28657 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037053165
293 rdf:type schema:CreativeWork
294 https://doi.org/10.1002/gcc.20012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043319717
295 rdf:type schema:CreativeWork
296 https://doi.org/10.1002/gcc.20906 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024119322
297 rdf:type schema:CreativeWork
298 https://doi.org/10.1002/gcc.21980 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042133616
299 rdf:type schema:CreativeWork
300 https://doi.org/10.1002/gcc.2870090309 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036786381
301 rdf:type schema:CreativeWork
302 https://doi.org/10.1002/ijc.28694 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045326685
303 rdf:type schema:CreativeWork
304 https://doi.org/10.1002/jor.22827 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008319491
305 rdf:type schema:CreativeWork
306 https://doi.org/10.1002/jor.23002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039814334
307 rdf:type schema:CreativeWork
308 https://doi.org/10.1002/path.2564 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053498221
309 rdf:type schema:CreativeWork
310 https://doi.org/10.1016/j.bbrc.2003.12.203 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026079079
311 rdf:type schema:CreativeWork
312 https://doi.org/10.1016/j.bbrc.2010.08.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029173434
313 rdf:type schema:CreativeWork
314 https://doi.org/10.1016/j.cancergencyto.2004.08.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020596531
315 rdf:type schema:CreativeWork
316 https://doi.org/10.1016/j.ccr.2007.02.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032459379
317 rdf:type schema:CreativeWork
318 https://doi.org/10.1016/j.ijrobp.2006.09.025 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030092950
319 rdf:type schema:CreativeWork
320 https://doi.org/10.1016/j.ijrobp.2008.04.044 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029900120
321 rdf:type schema:CreativeWork
322 https://doi.org/10.1016/j.jamcollsurg.2013.10.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038656420
323 rdf:type schema:CreativeWork
324 https://doi.org/10.1016/j.pharmthera.2012.08.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024872275
325 rdf:type schema:CreativeWork
326 https://doi.org/10.1016/s0046-8177(97)90060-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038179190
327 rdf:type schema:CreativeWork
328 https://doi.org/10.1016/s0140-6736(05)66954-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037998653
329 rdf:type schema:CreativeWork
330 https://doi.org/10.1016/s0165-4608(96)00436-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012233162
331 rdf:type schema:CreativeWork
332 https://doi.org/10.1016/s0360-3016(02)03864-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045088465
333 rdf:type schema:CreativeWork
334 https://doi.org/10.1016/s0360-3016(99)00559-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051637003
335 rdf:type schema:CreativeWork
336 https://doi.org/10.1016/s1470-2045(04)01709-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027590690
337 rdf:type schema:CreativeWork
338 https://doi.org/10.1053/adpa.2000.8133 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010986560
339 rdf:type schema:CreativeWork
340 https://doi.org/10.1073/pnas.1209414109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028210372
341 rdf:type schema:CreativeWork
342 https://doi.org/10.1073/pnas.85.7.2215 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009128451
343 rdf:type schema:CreativeWork
344 https://doi.org/10.1093/emboj/18.1.188 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032202617
345 rdf:type schema:CreativeWork
346 https://doi.org/10.1097/00000478-197912000-00004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005237630
347 rdf:type schema:CreativeWork
348 https://doi.org/10.1097/00000478-198703000-00001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021594770
349 rdf:type schema:CreativeWork
350 https://doi.org/10.1097/00000478-199411000-00009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053187182
351 rdf:type schema:CreativeWork
352 https://doi.org/10.1097/00000478-199703000-00002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060122273
353 rdf:type schema:CreativeWork
354 https://doi.org/10.1097/01.brs.0000251863.76595.a2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004763745
355 rdf:type schema:CreativeWork
356 https://doi.org/10.1097/01.sla.0000086542.11899.38 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060331828
357 rdf:type schema:CreativeWork
358 https://doi.org/10.1097/cco.0b013e32834796e6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019730037
359 rdf:type schema:CreativeWork
360 https://doi.org/10.1097/coh.0b013e32833ed177 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019907000
361 rdf:type schema:CreativeWork
362 https://doi.org/10.1097/pap.0000000000000101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013840161
363 rdf:type schema:CreativeWork
364 https://doi.org/10.1097/pas.0b013e3181dbf2f7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049840548
365 rdf:type schema:CreativeWork
366 https://doi.org/10.1097/pas.0b013e3181e5dc49 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037615990
367 rdf:type schema:CreativeWork
368 https://doi.org/10.1158/0008-5472.can-11-0890 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018835959
369 rdf:type schema:CreativeWork
370 https://doi.org/10.1158/0008-5472.can-11-3027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043301400
371 rdf:type schema:CreativeWork
372 https://doi.org/10.1158/1078-0432.ccr-08-3185 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041953362
373 rdf:type schema:CreativeWork
374 https://doi.org/10.1158/1078-0432.ccr-11-0193 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021904198
375 rdf:type schema:CreativeWork
376 https://doi.org/10.1158/1078-0432.ccr-15-1522 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063225041
377 rdf:type schema:CreativeWork
378 https://doi.org/10.1158/1535-7163.mct-14-0387 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007772039
379 rdf:type schema:CreativeWork
380 https://doi.org/10.1158/2159-8290.cd-11-0181 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006466734
381 rdf:type schema:CreativeWork
382 https://doi.org/10.1200/jco.2005.04.754 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017153509
383 rdf:type schema:CreativeWork
384 https://doi.org/10.1200/jco.2008.18.0802 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017397932
385 rdf:type schema:CreativeWork
386 https://doi.org/10.1200/jco.2010.28.5635 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021222916
387 rdf:type schema:CreativeWork
388 https://doi.org/10.1200/jco.2015.63.3651 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006803515
389 rdf:type schema:CreativeWork
390 https://doi.org/10.1586/14737140.2014.869173 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027674042
391 rdf:type schema:CreativeWork
392 https://doi.org/10.2217/fon.14.90 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042530431
393 rdf:type schema:CreativeWork
394 https://doi.org/10.2353/ajpath.2008.070284 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014083519
395 rdf:type schema:CreativeWork
396 https://doi.org/10.3109/02841868309134353 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003663816
397 rdf:type schema:CreativeWork
398 https://doi.org/10.3389/fgene.2013.00142 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042400693
399 rdf:type schema:CreativeWork
400 https://doi.org/10.3389/fgene.2013.00214 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010204225
401 rdf:type schema:CreativeWork
402 https://doi.org/10.3892/mmr.2011.426 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071520065
403 rdf:type schema:CreativeWork
404 https://www.grid.ac/institutes/grid.261331.4 schema:alternateName The Ohio State University
405 schema:name Department of Molecular Virology, Immunology, and Medical Genetics, The Ohio State University, Columbus, OH, USA
406 Department of Pathology, The Ohio State University, Columbus, OH, USA
407 Division of Surgical Oncology, Department of Surgery, Wexner Medical Center, The Ohio State University, 410W 10th Ave., 43210, Columbus, OH, USA
408 The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA
409 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...