Dengue virus life cycle: viral and host factors modulating infectivity View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2010-08

AUTHORS

Izabela A. Rodenhuis-Zybert, Jan Wilschut, Jolanda M. Smit

ABSTRACT

Dengue virus (DENV 1-4) represents a major emerging arthropod-borne pathogen. All four DENV serotypes are prevalent in the (sub) tropical regions of the world and infect 50-100 million individuals annually. Whereas the majority of DENV infections proceed asymptomatically or result in self-limited dengue fever, an increasing number of patients present more severe manifestations, such as dengue hemorrhagic fever and dengue shock syndrome. In this review we will give an overview of the infectious life cycle of DENV and will discuss the viral and host factors that are important in controlling DENV infection. More... »

PAGES

2773-2786

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/s00018-010-0357-z

    DOI

    http://dx.doi.org/10.1007/s00018-010-0357-z

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1009319554

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/20372965


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