The elusive engine in Myxococcus xanthus gliding motility View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2007-07-26

AUTHORS

T. Mignot

ABSTRACT

.Bacterial motility is essential for chemotaxis, virulence and complex social interactions leading to biofilm and fruiting body formation. Although bacterial swimming in liquids with a flagellum is well understood, little is known regarding bacterial movements across solid surfaces. Gliding motility, one such mode of locomotion, has remained largely mysterious because cells move smoothly along their long axis in the absence of any visible organelle. In this review, I discuss recent evidence that focal adhesion systems mediate gliding motility in the social bacterium Myxococcus xanthus and combine this evidence with previous work to suggest a new working hypothesis inspired from knowledge in apicomplexan parasites. I then propose experimental directions to test the model and compare it to other pre-existing models. Finally, evidence on gliding mechanisms of selected organisms are presented to ask whether some features of the model have precedents in other bacteria and whether this complex biological process could be explained by a single mechanism or involves multiple distinct mechanisms. More... »

PAGES

2733-2745

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00018-007-7176-x

DOI

http://dx.doi.org/10.1007/s00018-007-7176-x

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1028646511

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/17653507


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