Cys-tRNACys formation and cysteine biosynthesis in methanogenic archaea: two faces of the same problem? View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2004-10

AUTHORS

A. Ambrogelly, S. Kamtekar, A. Sauerwald, B. Ruan, D. Tumbula-Hansen, D. Kennedy, I. Ahel, D. Söll

ABSTRACT

Aminoacyl-tRNA (transfer RNA) synthetases are essential components of the cellular translation machinery as they provide the ribosome with aminoacyl-tRNAs. Aminoacyl-tRNA synthesis is generally well understood. However, the mechanism of Cys-tRNACys formation in three methanogenic archaea ( Methanocaldococcus jannaschii, Methanothermobacter thermautotrophicus and Methanopyrus kandleri) is still unknown, since no recognizable gene for a canonical cysteinyl-tRNA synthetase could be identified in the genome sequences of these organisms. Here we review the different routes recently proposed for Cys-tRNACys formation and discuss its possible link with cysteine biosynthesis in these methanogenic archaea. More... »

PAGES

2437-2445

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00018-004-4194-9

DOI

http://dx.doi.org/10.1007/s00018-004-4194-9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1031819156

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15526152


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RDF/XML is a standard XML format for linked data.

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