The Wiskott-Aldrich syndrome View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2004-09

AUTHORS

J. S. Orange, K. D. Stone, S. E. Turvey, K. Krzewski

ABSTRACT

The Wiskott-Aldrich Syndrome (WAS) is an inherited immunodeficiency caused by a variety of mutations in the gene encoding the WAS protein (WASp). WASp is expressed in hematopoetic cells and facilitates the reorganization of the actin cytoskeleton in response to many important cell stimuli. Extensive study of WAS and more recently WASp has given great insight into the relevance of this molecule and related molecules to both basic cell biology and human immune defenses. More... »

PAGES

2361-2385

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/s00018-004-4086-z

DOI

http://dx.doi.org/10.1007/s00018-004-4086-z

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1032626186

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15378206


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