Stellenwert der hyperbaren Sauerstofftherapie bei chronischen Wunden View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2001-06

AUTHORS

Wolf Mutschler, Claus-Martin Muth, Frank Rösken

ABSTRACT

Chronic wounds are defined as long-lasting defects in which necrosis, hypoxia, and acidosis cannot be overcome, so that continuous inflammation is present. This in turn means that insufficient granulation tissue develops, or even none at all, and re-epithelialization is delayed or impossible. In such problem wounds as diabetic foot syndrome, infected traumatic soft tissue defects or decubital ulcers hyperbaric oxygen therapy (HBO) can be useful when there is a quantifiable problem with hypoxia, providing it is viewed as one option in an 8-step-algorithm including conservative and operative procedures. Indications, patient suitability criteria, transcutaneous O2 measurement technique, technical standards and costs are presented. Studies in cell cultures and experimental animals in addition to clinical studies (evidence class I and II) clearly demonstrate that HBO given as an adjunctive therapy reduces the rate of major amputations in diabetic foot syndrome and improves the wound healing rate in chronic varicose ulcers. In addition, after HBO graft or flap failure is less frequent in tissue that is poorly vascularized as a result of irradiation. HBO can no longer be described, as it was in the past, as “a therapy in search of diseases”. More... »

PAGES

s267-s271

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/pl00014725

DOI

http://dx.doi.org/10.1007/pl00014725

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1016198140


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