Propionic acid production by whole cells of Propionibacterium freudenreichii View Full Text


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Article Info

DATE

1999-02

AUTHORS

K. Balamurugan, V. Venkata Dasu, T. Panda

ABSTRACT

The microbial production of propionic acid by Propionibacterium freudenreichii NCIM 2111, has been studied in this communication. Shake-flask studies were carried out to determine the optimum combination of various process parameters like stab age, inoculum age, inoculum level, medium constituents, temperature, and the initial pH for maximizing the production of propionic acid by using central composite design method. The system was found to exhibit product inhibition and hence the product inhibition kinetics was studied. A two parameter kinetic model, taking into account of the product inhibition, was proposed. Leudeking and Piret model was used to describe the production kinetics. The result from the shake-flask studies were compared with that obtained from mechanically stirred batch bioreactor and total recycle batch bioreactor. More... »

PAGES

109-116

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/pl00009039

DOI

http://dx.doi.org/10.1007/pl00009039

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1027585035


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