Septal innervation of mossy cells in the hilus of the rat dentate gyrus: an anterograde tracing and intracellular labeling study View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1997-05

AUTHORS

Joachim Lübke, Thomas Deller, M. Frotscher

ABSTRACT

Mossy cells in the hilus of the rat dentate gyrus are the main cells of origin of the dentate commissural and associational projections. They project along the septotemporal axis of the dentate gyrus and may thus influence the hippocampal signal flow in a longitudinal direction. To analyze the septal innervation of these hilar neurons, anterograde tracing with Phaseolus vulgaris leucoagglutinin (PHAL) was used in combination with intracellular labeling of mossy cells (Lucifer yellow). Anterogradely labeled septal fibers impinge on proximal and distal dendrites of hilar mossy cells but spare the cell body. In contrast, numerous aspiny hilar neurons, presumably GABAergic interneurons, receive a septal innervation on their somata and proximal primary dendrites. These data demonstrate that septal fibers show a specificity for the dendritic segments of hilar mossy cells. Since mossy cells project predominantly to adjacent hippocampal lamellae, the activity of adjacent portions of the dentate gyrus may be influenced by the septal input onto these neurons. More... »

PAGES

423-432

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/pl00005651

DOI

http://dx.doi.org/10.1007/pl00005651

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1013145137

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/9187278


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Neurosciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dendrites", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dentate Gyrus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fluorescent Dyes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Interneurons", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Isoquinolines", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Microinjections", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Nerve Fibers", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neurons", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phytohemagglutinins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats, Sprague-Dawley", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Septum Pellucidum", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Institute of Anatomy, University of Freiburg, P.O. Box 111 D-79001 Freiburg, Germany; Fax: +49\u2013761\u2013203\u20135054, DE", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Institute of Anatomy, University of Freiburg, P.O. Box 111 D-79001 Freiburg, Germany; Fax: +49\u2013761\u2013203\u20135054, DE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "L\u00fcbke", 
        "givenName": "Joachim", 
        "id": "sg:person.0622676353.75", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0622676353.75"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Anatomy, University of Freiburg, P.O. Box 111 D-79001 Freiburg, Germany; Fax: +49\u2013761\u2013203\u20135054, DE", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Institute of Anatomy, University of Freiburg, P.O. Box 111 D-79001 Freiburg, Germany; Fax: +49\u2013761\u2013203\u20135054, DE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Deller", 
        "givenName": "Thomas", 
        "id": "sg:person.01125311260.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01125311260.54"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Anatomy, University of Freiburg, P.O. Box 111 D-79001 Freiburg, Germany; Fax: +49\u2013761\u2013203\u20135054, DE", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Institute of Anatomy, University of Freiburg, P.O. Box 111 D-79001 Freiburg, Germany; Fax: +49\u2013761\u2013203\u20135054, DE"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Frotscher", 
        "givenName": "M.", 
        "id": "sg:person.0663133375.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0663133375.20"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "1997-05", 
    "datePublishedReg": "1997-05-01", 
    "description": "Abstract\u2002Mossy cells in the hilus of the rat dentate gyrus are the main cells of origin of the dentate commissural and associational projections. They project along the septotemporal axis of the dentate gyrus and may thus influence the hippocampal signal flow in a longitudinal direction. To analyze the septal innervation of these hilar neurons, anterograde tracing with Phaseolus vulgaris leucoagglutinin (PHAL) was used in combination with intracellular labeling of mossy cells (Lucifer yellow). Anterogradely labeled septal fibers impinge on proximal and distal dendrites of hilar mossy cells but spare the cell body. In contrast, numerous aspiny hilar neurons, presumably GABAergic interneurons, receive a septal innervation on their somata and proximal primary dendrites. These data demonstrate that septal fibers show a specificity for the dendritic segments of hilar mossy cells. Since mossy cells project predominantly to adjacent hippocampal lamellae, the activity of adjacent portions of the dentate gyrus may be influenced by the septal input onto these neurons.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/pl00005651", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1005581", 
        "issn": [
          "0014-4819", 
          "1432-1106"
        ], 
        "name": "Experimental Brain Research", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "114"
      }
    ], 
    "keywords": [
      "hilar mossy cells", 
      "mossy cells", 
      "rat dentate gyrus", 
      "dentate gyrus", 
      "Phaseolus vulgaris leucoagglutinin", 
      "septal innervation", 
      "hilar neurons", 
      "septal fibers", 
      "hippocampal lamellae", 
      "associational projections", 
      "GABAergic interneurons", 
      "distal dendrites", 
      "septotemporal axis", 
      "septal input", 
      "dendritic segments", 
      "cell bodies", 
      "innervation", 
      "gyrus", 
      "intracellular labeling", 
      "neurons", 
      "hilus", 
      "main cells", 
      "primary dendrites", 
      "cells", 
      "dendrites", 
      "interneurons", 
      "leucoagglutinin", 
      "labeling studies", 
      "adjacent portions", 
      "specificity", 
      "activity", 
      "labeling", 
      "study", 
      "fibers", 
      "contrast", 
      "body", 
      "segments", 
      "combination", 
      "data", 
      "portion", 
      "axis", 
      "projections", 
      "origin", 
      "signal flow", 
      "lamellae", 
      "flow", 
      "input", 
      "direction", 
      "longitudinal direction"
    ], 
    "name": "Septal innervation of mossy cells in the hilus of the rat dentate gyrus: an anterograde tracing and intracellular labeling study", 
    "pagination": "423-432", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1013145137"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/pl00005651"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "9187278"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/pl00005651", 
      "https://app.dimensions.ai/details/publication/pub.1013145137"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-05-10T09:44", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220509/entities/gbq_results/article/article_280.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/pl00005651"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/pl00005651'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/pl00005651'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/pl00005651'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/pl00005651'


 

This table displays all metadata directly associated to this object as RDF triples.

185 TRIPLES      21 PREDICATES      91 URIs      83 LITERALS      22 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/pl00005651 schema:about N16bc38c59a4c4040ab7aad343f5d694d
2 N24a233af03034795a08051b98eafa8cf
3 N2ad2038188ce4d7b8cda88c5d484d1bf
4 N33ecd915e8144895aba48a3d9ae74f75
5 N46b3f4866bfe47caa65639128a90a19e
6 N697258de27ab4f699d0a7e1f61bc20be
7 N7db9a1166a5b47dab3f6e079efcb3ddf
8 N853354c4526a47b99734782770bc3299
9 N8c8a65f3ebd24387bb7c64ba155633cf
10 N97f0f7feb81d4e9281640505cbaa851c
11 Nb03fd2f6d19242c79969507f44890616
12 Nb1fa15b7c4274c829fae9eb378887569
13 Nb4cad4c109c645d89acd9bdc51d623f2
14 Nde359a6f5013487782b0d796c6703536
15 Ne3840d18c4a54ebd8db47fccd52e56a1
16 anzsrc-for:11
17 anzsrc-for:1109
18 schema:author N12827ea77fa64d80bf49623bbaee3b11
19 schema:datePublished 1997-05
20 schema:datePublishedReg 1997-05-01
21 schema:description Abstract Mossy cells in the hilus of the rat dentate gyrus are the main cells of origin of the dentate commissural and associational projections. They project along the septotemporal axis of the dentate gyrus and may thus influence the hippocampal signal flow in a longitudinal direction. To analyze the septal innervation of these hilar neurons, anterograde tracing with Phaseolus vulgaris leucoagglutinin (PHAL) was used in combination with intracellular labeling of mossy cells (Lucifer yellow). Anterogradely labeled septal fibers impinge on proximal and distal dendrites of hilar mossy cells but spare the cell body. In contrast, numerous aspiny hilar neurons, presumably GABAergic interneurons, receive a septal innervation on their somata and proximal primary dendrites. These data demonstrate that septal fibers show a specificity for the dendritic segments of hilar mossy cells. Since mossy cells project predominantly to adjacent hippocampal lamellae, the activity of adjacent portions of the dentate gyrus may be influenced by the septal input onto these neurons.
22 schema:genre article
23 schema:inLanguage en
24 schema:isAccessibleForFree false
25 schema:isPartOf N8c0e909c20b34e67a8f66f12fdfb7e25
26 Nb1b397bd08d64f7d8a00946e26e784e7
27 sg:journal.1005581
28 schema:keywords GABAergic interneurons
29 Phaseolus vulgaris leucoagglutinin
30 activity
31 adjacent portions
32 associational projections
33 axis
34 body
35 cell bodies
36 cells
37 combination
38 contrast
39 data
40 dendrites
41 dendritic segments
42 dentate gyrus
43 direction
44 distal dendrites
45 fibers
46 flow
47 gyrus
48 hilar mossy cells
49 hilar neurons
50 hilus
51 hippocampal lamellae
52 innervation
53 input
54 interneurons
55 intracellular labeling
56 labeling
57 labeling studies
58 lamellae
59 leucoagglutinin
60 longitudinal direction
61 main cells
62 mossy cells
63 neurons
64 origin
65 portion
66 primary dendrites
67 projections
68 rat dentate gyrus
69 segments
70 septal fibers
71 septal innervation
72 septal input
73 septotemporal axis
74 signal flow
75 specificity
76 study
77 schema:name Septal innervation of mossy cells in the hilus of the rat dentate gyrus: an anterograde tracing and intracellular labeling study
78 schema:pagination 423-432
79 schema:productId N2f94c7a0db704cdd9691b244ccc845c4
80 N964b6a31f63e48fbaf890608e1b90524
81 N9da4b082f9c949d3b7025ed5f06ce124
82 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013145137
83 https://doi.org/10.1007/pl00005651
84 schema:sdDatePublished 2022-05-10T09:44
85 schema:sdLicense https://scigraph.springernature.com/explorer/license/
86 schema:sdPublisher Nbe5b36c8faac4f8ab9c03a5329a581e3
87 schema:url https://doi.org/10.1007/pl00005651
88 sgo:license sg:explorer/license/
89 sgo:sdDataset articles
90 rdf:type schema:ScholarlyArticle
91 N12827ea77fa64d80bf49623bbaee3b11 rdf:first sg:person.0622676353.75
92 rdf:rest Ndc4e5015f35340dba9204bde82105604
93 N16bc38c59a4c4040ab7aad343f5d694d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Dendrites
95 rdf:type schema:DefinedTerm
96 N24a233af03034795a08051b98eafa8cf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Dentate Gyrus
98 rdf:type schema:DefinedTerm
99 N2ad2038188ce4d7b8cda88c5d484d1bf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
100 schema:name Septum Pellucidum
101 rdf:type schema:DefinedTerm
102 N2f94c7a0db704cdd9691b244ccc845c4 schema:name dimensions_id
103 schema:value pub.1013145137
104 rdf:type schema:PropertyValue
105 N33ecd915e8144895aba48a3d9ae74f75 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Nerve Fibers
107 rdf:type schema:DefinedTerm
108 N46b3f4866bfe47caa65639128a90a19e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Rats
110 rdf:type schema:DefinedTerm
111 N6136e634e5bf4b8fb8ed12cb408733b1 rdf:first sg:person.0663133375.20
112 rdf:rest rdf:nil
113 N697258de27ab4f699d0a7e1f61bc20be schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Microinjections
115 rdf:type schema:DefinedTerm
116 N7db9a1166a5b47dab3f6e079efcb3ddf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Rats, Sprague-Dawley
118 rdf:type schema:DefinedTerm
119 N853354c4526a47b99734782770bc3299 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Fluorescent Dyes
121 rdf:type schema:DefinedTerm
122 N8c0e909c20b34e67a8f66f12fdfb7e25 schema:issueNumber 3
123 rdf:type schema:PublicationIssue
124 N8c8a65f3ebd24387bb7c64ba155633cf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Animals
126 rdf:type schema:DefinedTerm
127 N964b6a31f63e48fbaf890608e1b90524 schema:name doi
128 schema:value 10.1007/pl00005651
129 rdf:type schema:PropertyValue
130 N97f0f7feb81d4e9281640505cbaa851c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Phytohemagglutinins
132 rdf:type schema:DefinedTerm
133 N9da4b082f9c949d3b7025ed5f06ce124 schema:name pubmed_id
134 schema:value 9187278
135 rdf:type schema:PropertyValue
136 Nb03fd2f6d19242c79969507f44890616 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
137 schema:name Interneurons
138 rdf:type schema:DefinedTerm
139 Nb1b397bd08d64f7d8a00946e26e784e7 schema:volumeNumber 114
140 rdf:type schema:PublicationVolume
141 Nb1fa15b7c4274c829fae9eb378887569 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Female
143 rdf:type schema:DefinedTerm
144 Nb4cad4c109c645d89acd9bdc51d623f2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Neurons
146 rdf:type schema:DefinedTerm
147 Nbe5b36c8faac4f8ab9c03a5329a581e3 schema:name Springer Nature - SN SciGraph project
148 rdf:type schema:Organization
149 Ndc4e5015f35340dba9204bde82105604 rdf:first sg:person.01125311260.54
150 rdf:rest N6136e634e5bf4b8fb8ed12cb408733b1
151 Nde359a6f5013487782b0d796c6703536 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Male
153 rdf:type schema:DefinedTerm
154 Ne3840d18c4a54ebd8db47fccd52e56a1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
155 schema:name Isoquinolines
156 rdf:type schema:DefinedTerm
157 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
158 schema:name Medical and Health Sciences
159 rdf:type schema:DefinedTerm
160 anzsrc-for:1109 schema:inDefinedTermSet anzsrc-for:
161 schema:name Neurosciences
162 rdf:type schema:DefinedTerm
163 sg:journal.1005581 schema:issn 0014-4819
164 1432-1106
165 schema:name Experimental Brain Research
166 schema:publisher Springer Nature
167 rdf:type schema:Periodical
168 sg:person.01125311260.54 schema:affiliation grid-institutes:None
169 schema:familyName Deller
170 schema:givenName Thomas
171 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01125311260.54
172 rdf:type schema:Person
173 sg:person.0622676353.75 schema:affiliation grid-institutes:None
174 schema:familyName Lübke
175 schema:givenName Joachim
176 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0622676353.75
177 rdf:type schema:Person
178 sg:person.0663133375.20 schema:affiliation grid-institutes:None
179 schema:familyName Frotscher
180 schema:givenName M.
181 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0663133375.20
182 rdf:type schema:Person
183 grid-institutes:None schema:alternateName Institute of Anatomy, University of Freiburg, P.O. Box 111 D-79001 Freiburg, Germany; Fax: +49–761–203–5054, DE
184 schema:name Institute of Anatomy, University of Freiburg, P.O. Box 111 D-79001 Freiburg, Germany; Fax: +49–761–203–5054, DE
185 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...