Vascular disease in younger-onset diabetes: comparison of European, Asian and American Indian cohorts of the WHO multinational study of vascular ... View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2001-09

AUTHORS

E. T. Lee, M. Lu, P. H. Bennett, H. Keen, and the WHO Multinational Study Group

ABSTRACT

.Aims/hypothesis: This study compared the incidence of vascular disease in subjects with younger-onset diabetes from different ethnic groups. Methods: The incidence of vascular disease end-points has been studied in a sub-group (n = 994) of participants of the World Health Organization Multinational Study of Vascular Disease in Diabetes (WHO MSVDD) who had younger-onset diabetes (diagnosed before the age of 30 years). The study participants have been divided into European (n = 631), Asian (n = 84) and American Indian (n = 91) cohorts. Results: For Type I (insulin-dependent) and Type II (non-insulin-dependent) diabetes mellitus, American Indian men had a higher incidence of lower-extremity amputation and renal failure than the other cohorts, whereas European women had a higher incidence of angina than other cohorts. American Indians also had a higher incidence of any retinopathy, clinical proteinuria and albuminuria than the European and Asian cohorts. Conclusion/interpretation: This study confirms the high burden of large and small-vessel disease complications manifest in American Indian people with younger-onset diabetes. [Diabetologia (2001) 44 [Suppl 2]: S 78–S 81] More... »

PAGES

s78

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/pl00002943

DOI

http://dx.doi.org/10.1007/pl00002943

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https://app.dimensions.ai/details/publication/pub.1004447776

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11587054


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