Stellenwert des Tumormarkers CA 19–9 in der Differentialdiagnose von Raumforderungen im Pankreaskopf View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1996-10

AUTHORS

T. Böttger, A. Haßdenteufel, J. Boddin, R. Küchle, T. Junginger, W. Prellwitz

ABSTRACT

Summary. In 96 patients (ductal pancreatic carcinoma, n = 34; periampullary carcinoma, n = 43; chronic pancreatitis, n = 19) the role of CA 19–9 in the diagnosis of lesions of the head of the pancreas were evaluated. The sensitivity for ductal pancreatic carcinoma was 73.3 %, for periampullary carcinoma 48.8 %, and specificity was 63.2 %. Carcinoembryonic antigen was elevated only in every fifth patient. Even when combining the two tumor markers no increase in sensitivity could be observed. The low specificity of 63 %, which decreased to 33 % in the case of obstructive jaundice, does not allow adequate preoperative differentiation between cancer patients and those with chronic pancreatitis. In cases of postoperatively elevated CA 19–9 level the prognosis is worse than in patients with normal tumor markers. More... »

PAGES

1007-1011

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/pl00002512

DOI

http://dx.doi.org/10.1007/pl00002512

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1054508111

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/9011418


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