Ontology type: schema:ScholarlyArticle
2007-10
AUTHORSE. Fiore, E. Giustarini, C. Mammoli, F. Fragomeni, D. Campani, I. Muller, A. Pinchera, C. Giani
ABSTRACTA high incidence of anti-thyroid antibodies (TAb) has been found in patients with breast cancer (BC). The aim of this study was to evaluate the prognostic value of TAb in a group of 47 women submitted to mastectomy for high malignancy degree BC. All patients were evaluated for thyroid disorders after breast surgery and before any anti-tumoral adjuvant therapy. Five yr after BC diagnosis 31/47 (65.9%) patients were alive (survivors group: SG) and 16/47 (34.1%) were dead (deaths group: DG). The overall prevalence of TAb was 15/47 (31.9%): 14/31 (45.1%) in SG and 1/16 (6.2%) in DG (p=0.008). Five-yr mortality was 15/32 (46.9%) in TAb- and 1/15 (6.7%) in TAb+ patients (p=0.01). Eight out of 47 (17.0%) patients had Hashimoto's thyroiditis and 7 of them (87.5%) were in SG. Estrogen receptor (ER) was measured in 43/47 (91.5%) BC specimens. ER was detected in 19/30 (63.0%) patients in SG and 3/13 (23.1%) in DG (p=0.01). Five-yr mortality was 10/21 (47.6%) in ER- and 3/22 (13.6%) in ER+ patients (p=0.008). Absence of ER expression [odds ratio (OR) 6.54; p=0.006] and absence of TAb (OR 9.37; p=0.03) were related to a higher mortality rate. TAb were detected in 8/21 (38.1%) ER- and in 7/22 (31.8%) ER+ patients; no relation was found between ER expression and TAb positivity (p=ns). Patients with ER+ and TAb+ have a better prognosis and the absence of a significant relationship between these two parameters suggests an independent prognostic role in high malignancy degree BC women. More... »
PAGES734-738
http://scigraph.springernature.com/pub.10.1007/bf03350810
DOIhttp://dx.doi.org/10.1007/bf03350810
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1048677891
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/17993764
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Oncology and Carcinogenesis",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Adult",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Aged",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Antibodies, Anti-Idiotypic",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Autoimmunity",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Breast Neoplasms",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Carcinoma, Ductal",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Disease Progression",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Female",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Follow-Up Studies",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Kaplan-Meier Estimate",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Lymphatic Metastasis",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Middle Aged",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Multivariate Analysis",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Predictive Value of Tests",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Prognosis",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Prospective Studies",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Receptors, Estrogen",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Regression Analysis",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Thyroid Gland",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Thyrotropin",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Thyroxine",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "University of Pisa",
"id": "https://www.grid.ac/institutes/grid.5395.a",
"name": [
"Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy"
],
"type": "Organization"
},
"familyName": "Fiore",
"givenName": "E.",
"id": "sg:person.01131637346.25",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01131637346.25"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Pisa",
"id": "https://www.grid.ac/institutes/grid.5395.a",
"name": [
"Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy"
],
"type": "Organization"
},
"familyName": "Giustarini",
"givenName": "E.",
"id": "sg:person.01107237611.57",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01107237611.57"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Pisa",
"id": "https://www.grid.ac/institutes/grid.5395.a",
"name": [
"Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy"
],
"type": "Organization"
},
"familyName": "Mammoli",
"givenName": "C.",
"id": "sg:person.01251717056.77",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01251717056.77"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Pisa",
"id": "https://www.grid.ac/institutes/grid.5395.a",
"name": [
"Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy"
],
"type": "Organization"
},
"familyName": "Fragomeni",
"givenName": "F.",
"id": "sg:person.0613661765.24",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0613661765.24"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Pisa",
"id": "https://www.grid.ac/institutes/grid.5395.a",
"name": [
"Department of Oncology, Unit of Pathology, University of Pisa, Pisa, Italy"
],
"type": "Organization"
},
"familyName": "Campani",
"givenName": "D.",
"id": "sg:person.01341670152.67",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341670152.67"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Pisa",
"id": "https://www.grid.ac/institutes/grid.5395.a",
"name": [
"Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy"
],
"type": "Organization"
},
"familyName": "Muller",
"givenName": "I.",
"id": "sg:person.01263423373.00",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01263423373.00"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Pisa",
"id": "https://www.grid.ac/institutes/grid.5395.a",
"name": [
"Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy"
],
"type": "Organization"
},
"familyName": "Pinchera",
"givenName": "A.",
"id": "sg:person.01344402654.02",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01344402654.02"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Pisa",
"id": "https://www.grid.ac/institutes/grid.5395.a",
"name": [
"Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy"
],
"type": "Organization"
},
"familyName": "Giani",
"givenName": "C.",
"id": "sg:person.0674444215.05",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0674444215.05"
],
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1530/eje.1.02108",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001665209"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/78630",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011809905",
"https://doi.org/10.1038/78630"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/78630",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011809905",
"https://doi.org/10.1038/78630"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s1074-7613(02)00480-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012436194"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1023/a:1005769925670",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017679677",
"https://doi.org/10.1023/a:1005769925670"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.coi.2003.09.018",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020085222"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.coi.2003.09.018",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020085222"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/1097-0142(197507)36:1<1::aid-cncr2820360102>3.0.co;2-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028624131"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/1097-0142(19930301)71:5<1780::aid-cncr2820710512>3.0.co;2-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033073838"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1084/jem.188.2.409",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040423918"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/bcr609",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045423949",
"https://doi.org/10.1186/bcr609"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1089/thy.2005.15.1253",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049257632"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1210/endo-125-3-1211",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064262649"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1210/jc.83.8.2711",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064300339"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1210/jcem-72-1-209",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064316597"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1210/jcem.81.3.8772562",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1064320095"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1200/jco.1999.17.5.1474",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1074460868"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1074665592",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1076977971",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1079019530",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1083227937",
"type": "CreativeWork"
}
],
"datePublished": "2007-10",
"datePublishedReg": "2007-10-01",
"description": "A high incidence of anti-thyroid antibodies (TAb) has been found in patients with breast cancer (BC). The aim of this study was to evaluate the prognostic value of TAb in a group of 47 women submitted to mastectomy for high malignancy degree BC. All patients were evaluated for thyroid disorders after breast surgery and before any anti-tumoral adjuvant therapy. Five yr after BC diagnosis 31/47 (65.9%) patients were alive (survivors group: SG) and 16/47 (34.1%) were dead (deaths group: DG). The overall prevalence of TAb was 15/47 (31.9%): 14/31 (45.1%) in SG and 1/16 (6.2%) in DG (p=0.008). Five-yr mortality was 15/32 (46.9%) in TAb- and 1/15 (6.7%) in TAb+ patients (p=0.01). Eight out of 47 (17.0%) patients had Hashimoto's thyroiditis and 7 of them (87.5%) were in SG. Estrogen receptor (ER) was measured in 43/47 (91.5%) BC specimens. ER was detected in 19/30 (63.0%) patients in SG and 3/13 (23.1%) in DG (p=0.01). Five-yr mortality was 10/21 (47.6%) in ER- and 3/22 (13.6%) in ER+ patients (p=0.008). Absence of ER expression [odds ratio (OR) 6.54; p=0.006] and absence of TAb (OR 9.37; p=0.03) were related to a higher mortality rate. TAb were detected in 8/21 (38.1%) ER- and in 7/22 (31.8%) ER+ patients; no relation was found between ER expression and TAb positivity (p=ns). Patients with ER+ and TAb+ have a better prognosis and the absence of a significant relationship between these two parameters suggests an independent prognostic role in high malignancy degree BC women.",
"genre": "research_article",
"id": "sg:pub.10.1007/bf03350810",
"inLanguage": [
"en"
],
"isAccessibleForFree": false,
"isPartOf": [
{
"id": "sg:journal.1088396",
"issn": [
"0391-4097",
"1720-8386"
],
"name": "Journal of Endocrinological Investigation",
"type": "Periodical"
},
{
"issueNumber": "9",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "30"
}
],
"name": "Favorable predictive value of thyroid autoimmunity in high aggressive breast cancer",
"pagination": "734-738",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"e7e4731c773f9528378de7e46ee69271d3a1c3c970ccc8ec4e8df3c3f18d0e95"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"17993764"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"7806594"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/bf03350810"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1048677891"
]
}
],
"sameAs": [
"https://doi.org/10.1007/bf03350810",
"https://app.dimensions.ai/details/publication/pub.1048677891"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-10T19:51",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8681_00000483.jsonl",
"type": "ScholarlyArticle",
"url": "http://link.springer.com/10.1007/BF03350810"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf03350810'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf03350810'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf03350810'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf03350810'
This table displays all metadata directly associated to this object as RDF triples.
263 TRIPLES
21 PREDICATES
70 URIs
43 LITERALS
31 BLANK NODES