Epatopatia e glucocorticoidi nella oftalmopatia basedowiana: un limite alla terapia? View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2008-06

AUTHORS

Maria Antonietta Altea, Eleonora Sisti, Aldo Pinchera, Claudio Marcocci, Michele Marinò

ABSTRACT

I glucocorticoidi (GC) per via endovenosa (ev) rappresentano lo strumento terapeutico più diffuso ed efficace per l’oftalmopatia basedowiana (OB). Tuttavia, l’osservazione di alcuni casi di danno epatico acuto (DEA) durante o dopo terapia con GC ev ha sollevato importanti interrogativi sulla sicurezza di questo tipo di terapia e sull’opportunità di effettuarla indiscriminatamente in tutti i pazienti con OB in cui sarebbe indicata. Un importante aspetto da considerare è se l’osservazione di DEA durante o dopo terapia con GC ev sia un evento casuale, o da mettere effettivamente in relazione con la terapia. A tale proposito, non esistono studi epidemiologici che consentano di confrontare la frequenza del DEA tra pazienti trattati con GC ev e popolazione generale. In questo articolo abbiamo analizzato in maniera retrospettiva i casi di DEA riportati in letteratura e gli studi su casistica disponibili, allo scopo di valutarne la frequenza e individuarne i possibili predisponenti. More... »

PAGES

48-53

References to SciGraph publications

Journal

TITLE

L'Endocrinologo

ISSUE

2

VOLUME

9

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf03344608

DOI

http://dx.doi.org/10.1007/bf03344608

DIMENSIONS

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