Myasthenia gravis in the elderly: a rare cause of undernutrition View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2012-08

AUTHORS

Anne Petit, Thierry Constans, Dominique Chavanne, Julien Praline, Karl Mondon, Caroline Hommet

ABSTRACT

Myasthenia gravis is not a frequent disease in the elderly. The diagnosis of this neuromuscular junction disease in the elderly is difficult because of comorbidities and the broad differential diagnosis. We report here the case of a 86-year-old woman referred to hospital for loss of weight and difficulties in feeding. She was cachectic and had been suffering from dysphagia for several weeks. One week later, her clinical state worsened with the appearance of ptosis and oropharyngeal dysfunction, disturbing eating and talking. Myasthenia gravis was suspected and confirmed by a positive acetylcholine receptor antibody titer. The clinical state of the patient unfortunately worsened, with acute respiratory insufficiency, causing death. Myasthenia gravis must be suspected in a context of dysphagia, swallowing difficulties and loss of weight. This diagnosis leads to specific and symptomatic treatment and allows neuromuscular blockade-inducing drugs to be avoided. More... »

PAGES

398-399

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf03325271

DOI

http://dx.doi.org/10.1007/bf03325271

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1008101054

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/23238315


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