Immune dysfunction in the elderly: Effect of thymic hormone administration on several in vivo and in vitro immune function parameters View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1990-12

AUTHORS

Umberto Fagiolo, A. Amadori, F. Borghesan, R. Zamarchi, M. L. Veronese, G. De Silvestro, E. Passarella, G. Crepaldi

ABSTRACT

The effects of short- term thymic hormone administration on age- associated immune function were evaluated. Two groups of individuals > 65 years of age were treated for 30 days with thymic extracts (TP1) or placebo; before and after this treatment a panel of in vitro and in vivo parameters was determined according to a very rigorous experimental protocol. In most individuals, TP1 treatment was associated with an improvement in cutaneous delayed- type response to PPD. Moreover, an increase in a circulating T cell subpopulation bearing the CD45R surface antigen (“virgin” T cells), and in NK cell cytotoxic activity was also observed in some subjects. Finally, lymphocyte responsiveness to PHA tended to increase, while no effect on lymphocyte ability to produce IL- 2 following mitogen stimulation was observed. These findings suggest that TP1 treatment may influence age- related alterations in immune function parameters in some subjects. (Again 2: 347–355, 1990) More... »

PAGES

347-355

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf03323947

DOI

http://dx.doi.org/10.1007/bf03323947

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1022354191

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2094375


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1107", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Immunology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged, 80 and over", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antigens", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antigens, Surface", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Division", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Membrane", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "HLA-DR Antigens", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hypersensitivity, Delayed", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immune System", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immune System Diseases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Interleukin-2", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Killer Cells, Natural", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mitogens", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Receptors, Interleukin-2", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Skin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Thymus Hormones", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tuberculin", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Institute of Internal Medicine, Via Giustiniani 2, 35128, Padova, Italy", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Institute of Internal Medicine, Via Giustiniani 2, 35128, Padova, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fagiolo", 
        "givenName": "Umberto", 
        "id": "sg:person.011273501214.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011273501214.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Oncology, University of Padova, Padova", 
          "id": "http://www.grid.ac/institutes/grid.5608.b", 
          "name": [
            "Institute of Oncology, University of Padova, Padova"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Amadori", 
        "givenName": "A.", 
        "id": "sg:person.0600652745.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0600652745.06"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Internal Medicine, Via Giustiniani 2, 35128, Padova, Italy", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Institute of Internal Medicine, Via Giustiniani 2, 35128, Padova, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Borghesan", 
        "givenName": "F.", 
        "id": "sg:person.01231067406.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01231067406.40"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Oncology, University of Padova, Padova", 
          "id": "http://www.grid.ac/institutes/grid.5608.b", 
          "name": [
            "Institute of Oncology, University of Padova, Padova"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zamarchi", 
        "givenName": "R.", 
        "id": "sg:person.0743025571.76", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0743025571.76"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Oncology, University of Padova, Padova", 
          "id": "http://www.grid.ac/institutes/grid.5608.b", 
          "name": [
            "Institute of Oncology, University of Padova, Padova"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Veronese", 
        "givenName": "M. L.", 
        "id": "sg:person.01101223120.68", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01101223120.68"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Central Laboratory Unit of Padova General Hospital, Padova", 
          "id": "http://www.grid.ac/institutes/grid.411474.3", 
          "name": [
            "Central Laboratory Unit of Padova General Hospital, Padova"
          ], 
          "type": "Organization"
        }, 
        "familyName": "De Silvestro", 
        "givenName": "G.", 
        "id": "sg:person.01211411447.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01211411447.44"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Serono Pharmaceutical, Milano, Italy", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Serono Pharmaceutical, Milano, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Passarella", 
        "givenName": "E.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institute of Internal Medicine, Via Giustiniani 2, 35128, Padova, Italy", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Institute of Internal Medicine, Via Giustiniani 2, 35128, Padova, Italy"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Crepaldi", 
        "givenName": "G.", 
        "id": "sg:person.01035716055.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01035716055.00"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf00917897", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006209808", 
          "https://doi.org/10.1007/bf00917897"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01561660", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033949208", 
          "https://doi.org/10.1007/bf01561660"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1990-12", 
    "datePublishedReg": "1990-12-01", 
    "description": "The effects of short- term thymic hormone administration on age- associated immune function were evaluated. Two groups of individuals > 65 years of age were treated for 30 days with thymic extracts (TP1) or placebo; before and after this treatment a panel of in vitro and in vivo parameters was determined according to a very rigorous experimental protocol. In most individuals, TP1 treatment was associated with an improvement in cutaneous delayed- type response to PPD. Moreover, an increase in a circulating T cell subpopulation bearing the CD45R surface antigen (\u201cvirgin\u201d T cells), and in NK cell cytotoxic activity was also observed in some subjects. Finally, lymphocyte responsiveness to PHA tended to increase, while no effect on lymphocyte ability to produce IL- 2 following mitogen stimulation was observed. These findings suggest that TP1 treatment may influence age- related alterations in immune function parameters in some subjects. (Again 2: 347\u2013355, 1990)", 
    "genre": "article", 
    "id": "sg:pub.10.1007/bf03323947", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1030201", 
        "issn": [
          "1594-0667", 
          "1720-8319"
        ], 
        "name": "Aging Clinical and Experimental Research", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "2"
      }
    ], 
    "keywords": [
      "immune function parameters", 
      "TP1 treatment", 
      "hormone administration", 
      "NK cell cytotoxic activity", 
      "delayed-type response", 
      "age-related alterations", 
      "cell cytotoxic activity", 
      "years of age", 
      "function parameters", 
      "immune dysfunction", 
      "thymic extract", 
      "lymphocytes' ability", 
      "immune function", 
      "surface antigen", 
      "mitogen stimulation", 
      "cell subpopulations", 
      "vivo parameters", 
      "treatment", 
      "administration", 
      "cytotoxic activity", 
      "group of individuals", 
      "most individuals", 
      "subjects", 
      "placebo", 
      "dysfunction", 
      "experimental protocol", 
      "antigen", 
      "individuals", 
      "stimulation", 
      "PPD", 
      "age", 
      "PHA", 
      "subpopulations", 
      "responsiveness", 
      "effect", 
      "vivo", 
      "alterations", 
      "days", 
      "group", 
      "years", 
      "findings", 
      "response", 
      "activity", 
      "extracts", 
      "increase", 
      "protocol", 
      "improvement", 
      "panel", 
      "rigorous experimental protocol", 
      "function", 
      "ability", 
      "IL", 
      "parameters", 
      "short- term thymic hormone administration", 
      "thymic hormone administration", 
      "age- associated immune function", 
      "cutaneous delayed- type response", 
      "CD45R surface antigen"
    ], 
    "name": "Immune dysfunction in the elderly: Effect of thymic hormone administration on several in vivo and in vitro immune function parameters", 
    "pagination": "347-355", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1022354191"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf03323947"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "2094375"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf03323947", 
      "https://app.dimensions.ai/details/publication/pub.1022354191"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-01-01T18:05", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220101/entities/gbq_results/article/article_240.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/bf03323947"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf03323947'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf03323947'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf03323947'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf03323947'


 

This table displays all metadata directly associated to this object as RDF triples.

264 TRIPLES      22 PREDICATES      107 URIs      97 LITERALS      27 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf03323947 schema:about N1bd2b5ea0def419c820fae023f8b8a5b
2 N1efaf4853ca047d58bcaa89da5cec488
3 N257e45ae471b4ec5a9927bd82302e951
4 N27b7832e2c8c4524808d20b725bbda06
5 N27ec604eefc64875a37280c4e9487643
6 N407f3768d3fd4ed39dc61f0c897f0198
7 N482b5c0eef5c485ab13c0b67b951bc3a
8 N4e4a706d92984cc5a7b663eb2355d211
9 N5ad52e8539d744f0a9639d392cb7b8b9
10 N5f2337a5a45449f28300aa9e956ec075
11 N6c63953edd7a4951aeb690cde9f1c3ba
12 N6e3deb0c3ebb4639a12d337381bf00bc
13 N89169b13b5c34260b976ac40d6d05f45
14 N962cca67778d4b8183b7100b2a57c439
15 Na6b8c2423d454d5e8461394d6b34caee
16 Naf5b00245f7d427d9d0970f690a285e1
17 Nd83c867240fb481a8607e5ab08238ed6
18 Nf3b5bcb363b14399bcdf1dc6e0e485bc
19 Nf49e92c197134e5ba73375a358cab360
20 Nfb3838786b3d4cac91108f4b6b5c52b2
21 anzsrc-for:11
22 anzsrc-for:1107
23 schema:author Na954dec747e649d1bc02afbed403d8ed
24 schema:citation sg:pub.10.1007/bf00917897
25 sg:pub.10.1007/bf01561660
26 schema:datePublished 1990-12
27 schema:datePublishedReg 1990-12-01
28 schema:description The effects of short- term thymic hormone administration on age- associated immune function were evaluated. Two groups of individuals > 65 years of age were treated for 30 days with thymic extracts (TP1) or placebo; before and after this treatment a panel of in vitro and in vivo parameters was determined according to a very rigorous experimental protocol. In most individuals, TP1 treatment was associated with an improvement in cutaneous delayed- type response to PPD. Moreover, an increase in a circulating T cell subpopulation bearing the CD45R surface antigen (“virgin” T cells), and in NK cell cytotoxic activity was also observed in some subjects. Finally, lymphocyte responsiveness to PHA tended to increase, while no effect on lymphocyte ability to produce IL- 2 following mitogen stimulation was observed. These findings suggest that TP1 treatment may influence age- related alterations in immune function parameters in some subjects. (Again 2: 347–355, 1990)
29 schema:genre article
30 schema:inLanguage en
31 schema:isAccessibleForFree false
32 schema:isPartOf Nee906931b4c04fababc27870926cd8d9
33 Nf280284b4fc54d35b19d3e372b43744f
34 sg:journal.1030201
35 schema:keywords CD45R surface antigen
36 IL
37 NK cell cytotoxic activity
38 PHA
39 PPD
40 TP1 treatment
41 ability
42 activity
43 administration
44 age
45 age- associated immune function
46 age-related alterations
47 alterations
48 antigen
49 cell cytotoxic activity
50 cell subpopulations
51 cutaneous delayed- type response
52 cytotoxic activity
53 days
54 delayed-type response
55 dysfunction
56 effect
57 experimental protocol
58 extracts
59 findings
60 function
61 function parameters
62 group
63 group of individuals
64 hormone administration
65 immune dysfunction
66 immune function
67 immune function parameters
68 improvement
69 increase
70 individuals
71 lymphocytes' ability
72 mitogen stimulation
73 most individuals
74 panel
75 parameters
76 placebo
77 protocol
78 response
79 responsiveness
80 rigorous experimental protocol
81 short- term thymic hormone administration
82 stimulation
83 subjects
84 subpopulations
85 surface antigen
86 thymic extract
87 thymic hormone administration
88 treatment
89 vivo
90 vivo parameters
91 years
92 years of age
93 schema:name Immune dysfunction in the elderly: Effect of thymic hormone administration on several in vivo and in vitro immune function parameters
94 schema:pagination 347-355
95 schema:productId N2555e54cf8cd434aac03ba47ded9f97b
96 N3d998c003b2246558d74049d88cd22be
97 Nb5c28b92560140d4af13dce16734e537
98 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022354191
99 https://doi.org/10.1007/bf03323947
100 schema:sdDatePublished 2022-01-01T18:05
101 schema:sdLicense https://scigraph.springernature.com/explorer/license/
102 schema:sdPublisher N0bdfce3ffa0340609a228152d561482e
103 schema:url https://doi.org/10.1007/bf03323947
104 sgo:license sg:explorer/license/
105 sgo:sdDataset articles
106 rdf:type schema:ScholarlyArticle
107 N0bdfce3ffa0340609a228152d561482e schema:name Springer Nature - SN SciGraph project
108 rdf:type schema:Organization
109 N17841cbb48004157a82607f789457028 schema:affiliation grid-institutes:None
110 schema:familyName Passarella
111 schema:givenName E.
112 rdf:type schema:Person
113 N1bd2b5ea0def419c820fae023f8b8a5b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Interleukin-2
115 rdf:type schema:DefinedTerm
116 N1efaf4853ca047d58bcaa89da5cec488 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Receptors, Interleukin-2
118 rdf:type schema:DefinedTerm
119 N2555e54cf8cd434aac03ba47ded9f97b schema:name dimensions_id
120 schema:value pub.1022354191
121 rdf:type schema:PropertyValue
122 N257e45ae471b4ec5a9927bd82302e951 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Immune System
124 rdf:type schema:DefinedTerm
125 N27b7832e2c8c4524808d20b725bbda06 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Immune System Diseases
127 rdf:type schema:DefinedTerm
128 N27ec604eefc64875a37280c4e9487643 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Male
130 rdf:type schema:DefinedTerm
131 N3d998c003b2246558d74049d88cd22be schema:name doi
132 schema:value 10.1007/bf03323947
133 rdf:type schema:PropertyValue
134 N407f3768d3fd4ed39dc61f0c897f0198 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Antigens, Surface
136 rdf:type schema:DefinedTerm
137 N411d744def9546e6a121f121ced5f5b5 rdf:first sg:person.01101223120.68
138 rdf:rest Ne07eb3bd2dc64daab0268c8210442a08
139 N45065d919e6a40519e77316370be8a02 rdf:first sg:person.0600652745.06
140 rdf:rest N83839a3d486f403c82bc49cf5038d0e8
141 N482b5c0eef5c485ab13c0b67b951bc3a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Killer Cells, Natural
143 rdf:type schema:DefinedTerm
144 N4e4a706d92984cc5a7b663eb2355d211 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Aged, 80 and over
146 rdf:type schema:DefinedTerm
147 N5ad52e8539d744f0a9639d392cb7b8b9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Mitogens
149 rdf:type schema:DefinedTerm
150 N5f196317866847939fe71c1b7573000e rdf:first sg:person.0743025571.76
151 rdf:rest N411d744def9546e6a121f121ced5f5b5
152 N5f2337a5a45449f28300aa9e956ec075 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Skin
154 rdf:type schema:DefinedTerm
155 N6c63953edd7a4951aeb690cde9f1c3ba schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Cell Division
157 rdf:type schema:DefinedTerm
158 N6e3deb0c3ebb4639a12d337381bf00bc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
159 schema:name Tuberculin
160 rdf:type schema:DefinedTerm
161 N83839a3d486f403c82bc49cf5038d0e8 rdf:first sg:person.01231067406.40
162 rdf:rest N5f196317866847939fe71c1b7573000e
163 N89169b13b5c34260b976ac40d6d05f45 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
164 schema:name Thymus Hormones
165 rdf:type schema:DefinedTerm
166 N962cca67778d4b8183b7100b2a57c439 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name Aged
168 rdf:type schema:DefinedTerm
169 Na6b8c2423d454d5e8461394d6b34caee schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name Hypersensitivity, Delayed
171 rdf:type schema:DefinedTerm
172 Na83a360ee18d41c0a44dfaa0b60d77ce rdf:first N17841cbb48004157a82607f789457028
173 rdf:rest Nad454a442e2146b38e096fbc88aa7806
174 Na954dec747e649d1bc02afbed403d8ed rdf:first sg:person.011273501214.58
175 rdf:rest N45065d919e6a40519e77316370be8a02
176 Nad454a442e2146b38e096fbc88aa7806 rdf:first sg:person.01035716055.00
177 rdf:rest rdf:nil
178 Naf5b00245f7d427d9d0970f690a285e1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
179 schema:name Antigens
180 rdf:type schema:DefinedTerm
181 Nb5c28b92560140d4af13dce16734e537 schema:name pubmed_id
182 schema:value 2094375
183 rdf:type schema:PropertyValue
184 Nd83c867240fb481a8607e5ab08238ed6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
185 schema:name Female
186 rdf:type schema:DefinedTerm
187 Ne07eb3bd2dc64daab0268c8210442a08 rdf:first sg:person.01211411447.44
188 rdf:rest Na83a360ee18d41c0a44dfaa0b60d77ce
189 Nee906931b4c04fababc27870926cd8d9 schema:issueNumber 4
190 rdf:type schema:PublicationIssue
191 Nf280284b4fc54d35b19d3e372b43744f schema:volumeNumber 2
192 rdf:type schema:PublicationVolume
193 Nf3b5bcb363b14399bcdf1dc6e0e485bc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
194 schema:name Cell Membrane
195 rdf:type schema:DefinedTerm
196 Nf49e92c197134e5ba73375a358cab360 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
197 schema:name Humans
198 rdf:type schema:DefinedTerm
199 Nfb3838786b3d4cac91108f4b6b5c52b2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
200 schema:name HLA-DR Antigens
201 rdf:type schema:DefinedTerm
202 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
203 schema:name Medical and Health Sciences
204 rdf:type schema:DefinedTerm
205 anzsrc-for:1107 schema:inDefinedTermSet anzsrc-for:
206 schema:name Immunology
207 rdf:type schema:DefinedTerm
208 sg:journal.1030201 schema:issn 1594-0667
209 1720-8319
210 schema:name Aging Clinical and Experimental Research
211 schema:publisher Springer Nature
212 rdf:type schema:Periodical
213 sg:person.01035716055.00 schema:affiliation grid-institutes:None
214 schema:familyName Crepaldi
215 schema:givenName G.
216 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01035716055.00
217 rdf:type schema:Person
218 sg:person.01101223120.68 schema:affiliation grid-institutes:grid.5608.b
219 schema:familyName Veronese
220 schema:givenName M. L.
221 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01101223120.68
222 rdf:type schema:Person
223 sg:person.011273501214.58 schema:affiliation grid-institutes:None
224 schema:familyName Fagiolo
225 schema:givenName Umberto
226 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011273501214.58
227 rdf:type schema:Person
228 sg:person.01211411447.44 schema:affiliation grid-institutes:grid.411474.3
229 schema:familyName De Silvestro
230 schema:givenName G.
231 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01211411447.44
232 rdf:type schema:Person
233 sg:person.01231067406.40 schema:affiliation grid-institutes:None
234 schema:familyName Borghesan
235 schema:givenName F.
236 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01231067406.40
237 rdf:type schema:Person
238 sg:person.0600652745.06 schema:affiliation grid-institutes:grid.5608.b
239 schema:familyName Amadori
240 schema:givenName A.
241 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0600652745.06
242 rdf:type schema:Person
243 sg:person.0743025571.76 schema:affiliation grid-institutes:grid.5608.b
244 schema:familyName Zamarchi
245 schema:givenName R.
246 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0743025571.76
247 rdf:type schema:Person
248 sg:pub.10.1007/bf00917897 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006209808
249 https://doi.org/10.1007/bf00917897
250 rdf:type schema:CreativeWork
251 sg:pub.10.1007/bf01561660 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033949208
252 https://doi.org/10.1007/bf01561660
253 rdf:type schema:CreativeWork
254 grid-institutes:None schema:alternateName Institute of Internal Medicine, Via Giustiniani 2, 35128, Padova, Italy
255 Serono Pharmaceutical, Milano, Italy
256 schema:name Institute of Internal Medicine, Via Giustiniani 2, 35128, Padova, Italy
257 Serono Pharmaceutical, Milano, Italy
258 rdf:type schema:Organization
259 grid-institutes:grid.411474.3 schema:alternateName Central Laboratory Unit of Padova General Hospital, Padova
260 schema:name Central Laboratory Unit of Padova General Hospital, Padova
261 rdf:type schema:Organization
262 grid-institutes:grid.5608.b schema:alternateName Institute of Oncology, University of Padova, Padova
263 schema:name Institute of Oncology, University of Padova, Padova
264 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...